Neuromodulation最新文献

{"title":"IS014 PHYSIOLOGICAL EFFECTS AND MECHANISMS OF ACTION OF SPINAL CORD STIMULATION TO TREAT PAIN: INSIGHTS FROM COMPUTATIONAL MODELS AND QUANTITATIVE SENSORY TESTING","authors":"Scott Lempka (Associate Professor)","doi":"10.1016/j.neurom.2024.09.023","DOIUrl":"10.1016/j.neurom.2024.09.023","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 1","pages":"Page S8"},"PeriodicalIF":3.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143164116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IS047 POSTSURGICAL MORBIDITY AND MORTALITY FAVORABLY INFORMS DEEP BRAIN STIMULATION FOR NEW INDICATIONS INCLUDING SCHIZOPHRENIA AND SCHIZOAFFECTIVE DISORDER","authors":"Judith Gault PhD , Patrick Hosokawa MSc , Daniel Kramer MD , Elyn Saks PhD , Paul Appelbaum MD , John Thompson PhD , Ann Olincy MD , Nicola Cascella MD , Akira Sawa MD , Wayne Goodman MD , Nidal Moukaddam MD , Sameer A. Sheth MD , William Anderson MD , Rachel A. Davis MD","doi":"10.1016/j.neurom.2024.09.056","DOIUrl":"10.1016/j.neurom.2024.09.056","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 1","pages":"Page S25"},"PeriodicalIF":3.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IS007 NON-INVASIVE BRAIN STIMULATION IN REHABILITATION: WHERE ARE WE AND WHERE ARE WE GOING?","authors":"Dylan Edwards (Director, Moss Rehabilitation Re)","doi":"10.1016/j.neurom.2024.09.016","DOIUrl":"10.1016/j.neurom.2024.09.016","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 1","pages":"Page S4"},"PeriodicalIF":3.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IS039 NEUROMODULATION FOR REFRACTORY EPILEPSY: PROGRESS TOWARDS LESS INVASIVE APPROACHES","authors":"Andreas Schulze-Bonhage MD","doi":"10.1016/j.neurom.2024.09.048","DOIUrl":"10.1016/j.neurom.2024.09.048","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 1","pages":"Page S21"},"PeriodicalIF":3.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143097393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Working Mechanism of Transcranial Direct Current Stimulation","authors":"Emma Lescrauwaet MSc ,&nbsp;Mathieu Sprengers MD, PhD ,&nbsp;Evelien Carrette PhD ,&nbsp;Chloé Algoet MD ,&nbsp;Ann Mertens MD, PhD ,&nbsp;Debby Klooster PhD ,&nbsp;Steven Beumer MSc ,&nbsp;Rob Mestrom PhD ,&nbsp;Robrecht Raedt PhD ,&nbsp;Paul Boon MD, PhD ,&nbsp;Kristl Vonck MD, PhD","doi":"10.1016/j.neurom.2024.05.002","DOIUrl":"10.1016/j.neurom.2024.05.002","url":null,"abstract":"<div><h3>Background</h3><div>Transcranial direct current stimulation (tDCS) is used to modulate neuronal activity, but the exact mechanism of action (MOA) is unclear. This study investigates tDCS-induced modulation of the corticospinal excitability and the underlying MOA. By anesthetizing the scalp before applying tDCS and by stimulating the cheeks, we investigated whether stimulation of peripheral and/or cranial nerves contributes to the effects of tDCS on corticospinal excitability.</div></div><div><h3>Materials and Methods</h3><div>In a randomized cross-over study, four experimental conditions with anodal direct current stimulation were compared in 19 healthy volunteers: 1) tDCS over the motor cortex (tDCS-MI), 2) tDCS over the motor cortex with a locally applied topical anesthetic (TA) on the scalp (tDCS-MI + TA), 3) DCS over the cheek region (DCS-C), and 4) sham tDCS over the motor cortex(sham). tDCS was applied for 20 minutes at 1 mA. Motor evoked potentials (MEPs) were measured before tDCS and immediately, 15, 30, 45, and 60 minutes after tDCS. A questionnaire was used to assess the tolerability of tDCS.</div></div><div><h3>Results</h3><div>A significant MEP amplitude increase compared with baseline was found 30 minutes after tDCS-MI, an effect still observed 60 minutes later; no time∗condition interaction effect was detected. In the other three conditions (tDCS-MI + TA, DCS-C, sham), no significant MEP modulation was found. The questionnaire indicated that side effects are significantly lower when the local anesthetic was applied before stimulation than in the other three conditions.</div></div><div><h3>Conclusions</h3><div>The significant MEP amplitude increase observed from 30 minutes on after tDCS-MI supports the modulatory effect of tDCS on corticospinal neurotransmission. This effect lasted one hour after stimulation. The absence of a significant modulation when a local anesthetic was applied suggests that effects of tDCS are not solely established through direct cortical stimulation but that stimulation of peripheral and/or cranial nerves also might contribute to tDCS-induced modulation.</div></div>","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 1","pages":"Pages 68-75"},"PeriodicalIF":3.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141327711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IS075 ARTIFICIAL INTELLIGENCE (AI) BRAIN IMAGING FOR SURGICAL TARGETING","authors":"Noam Harel PhD","doi":"10.1016/j.neurom.2024.09.084","DOIUrl":"10.1016/j.neurom.2024.09.084","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 1","pages":"Page S40"},"PeriodicalIF":3.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143097752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2025 Calendar of Events - January","authors":"","doi":"10.1016/S1094-7159(24)01255-8","DOIUrl":"10.1016/S1094-7159(24)01255-8","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 1","pages":"Page 190"},"PeriodicalIF":3.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143099420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IS015 MECHANISM OF PERIPHERAL NERVE STIMULATION (PNS), SPINAL CORD STIMULATION (SCS): SUPRASPINAL MECHANISMS AND MECHANISMS OF ACTION (MOA)","authors":"Eellan Sivanesan MD","doi":"10.1016/j.neurom.2024.09.024","DOIUrl":"10.1016/j.neurom.2024.09.024","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 1","pages":"Page S8"},"PeriodicalIF":3.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IS012 SURROUND INHIBITION MECHANISM OF ACTION","authors":"Warren Grill (Professor)","doi":"10.1016/j.neurom.2024.09.021","DOIUrl":"10.1016/j.neurom.2024.09.021","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 1","pages":"Page S7"},"PeriodicalIF":3.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IS050 BIOHYBRID REGENERATIVE INTERFACE","authors":"Damiano Barone MD, PhD","doi":"10.1016/j.neurom.2024.09.059","DOIUrl":"10.1016/j.neurom.2024.09.059","url":null,"abstract":"","PeriodicalId":19152,"journal":{"name":"Neuromodulation","volume":"28 1","pages":"Page S27"},"PeriodicalIF":3.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143102180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}