Neurointervention最新文献

{"title":"Adjustment of Malpositioned Woven EndoBridge Device Using Gooseneck Snare: Complication Management Technique.","authors":"Krishna Amuluru,&nbsp;Fawaz Al-Mufti,&nbsp;Daniel H Sahlein,&nbsp;John Scott,&nbsp;Andrew Denardo","doi":"10.5469/neuroint.2021.00318","DOIUrl":"https://doi.org/10.5469/neuroint.2021.00318","url":null,"abstract":"<p><p>The Woven EndoBridge (WEB) is an intrasaccular flow-disrupting device for the treatment of wide-necked saccular cerebral aneurysms. As with any neuroendovascular device, complications in the form of malpositioning and migration must be managed quickly and safely. Few studies have reported complication management techniques in instances of dislocated or migrated WEB devices. We retrospectively describe a case of a malpositioned WEB device that was successfully adjusted with the use of a gooseneck snare. Multiple other intra-procedural bailout strategies for management of WEB malposition and migration were considered, and are herein discussed. Operators should be aware of the causes of WEB malposition and a variety of bailout strategies.</p>","PeriodicalId":19140,"journal":{"name":"Neurointervention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/76/1a/neuroint-2021-00318.PMC8561038.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39505981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ten Years of Clinical Evaluation of the Woven EndoBridge: A Safe and Effective Treatment for Wide-Neck Bifurcation Aneurysms.","authors":"Laurent Pierot","doi":"10.5469/neuroint.2021.00395","DOIUrl":"https://doi.org/10.5469/neuroint.2021.00395","url":null,"abstract":"<p><p>Intrasaccular flow disruption is an innovative approach for the endovascular treatment of intracranial aneurysms. As of now, only one device is currently available worldwide: the Woven EndoBridge (WEB) device (MicroVention, Aliso Viejo, CA, USA). After 10 years of clinical use and careful clinical evaluation of the WEB device by multiple prospective, multicenter studies, this article is summarizing the current knowledge regarding this endovascular technique; indications, modalities, safety and efficacy of the WEB procedure are described.</p>","PeriodicalId":19140,"journal":{"name":"Neurointervention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7b/93/neuroint-2021-00395.PMC8561039.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39540729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silk® Flow Diverter Device for Intracranial Aneurysm Treatment: A Systematic Review and Meta-Analysis.","authors":"William A Florez,&nbsp;Ezequiel Garcia-Ballestas,&nbsp;Gabriel Alexander Quiñones-Ossa,&nbsp;Tariq Janjua,&nbsp;Subhas Konar,&nbsp;Amit Agrawal,&nbsp;Luis Rafael Moscote-Salazar","doi":"10.5469/neuroint.2021.00234","DOIUrl":"https://doi.org/10.5469/neuroint.2021.00234","url":null,"abstract":"<p><p>Flow diverters have become a critical instrument for complex aneurysms treatment. However, limited data are currently available regarding short and long-term outcomes for the Silk flow diverter. The objective of the study is to determine neurological prognosis and mortality rates for the Silk flow diversion device used in intracranial aneurysms. A systematic review with meta-analysis was performed using databases. The following descriptors were used for the search: \"SILK\", \"Flow Diverter\", \"Mortality\", and \"Prognosis\". The following data were extracted: mortality, good functional outcome, Glasgow outcome scale, complete or near-complete occlusion rates, rate of retreatment, and complications (thromboembolic and hemorrhagic complications). A total of 14 studies were selected. Among the 14 studies, 13 were retrospective observational cohort studies and 1 was a prospective observational cohort study. The mortality rate was 2.84%. The clinical good outcomes rate was 93.3%. The poor outcome rate was 6.6%. The overall thromboembolic complication rate was 6.06% (95% confidence interval [CI] 0.00-6.37, P=0.12, I2=3.13%). The total hemorrhagic complication rate was 1.62% (95% CI 0.00-5.34, P=0.28, I2=1.56%). The complete aneurysm occlusion rate was 80.4% (95% CI 8.65-9.38, P<0.0001, I2=9.09%). The Silk diverter device has a good safety and efficacy profile for treating intracranial aneurysms with high complete occlusion rates.</p>","PeriodicalId":19140,"journal":{"name":"Neurointervention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ab/fc/neuroint-2021-00234.PMC8561040.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39431767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethic Statement Correction: Peri-Aneurysmal Brain Edema in Native and Treated Aneurysms: The Role of Thrombosis.","authors":"Valeria Onofrj,&nbsp;Donatella Tampieri,&nbsp;Alessandro Cianfoni,&nbsp;Elisa Ventura","doi":"10.5469/neuroint.2020.00255.e1","DOIUrl":"https://doi.org/10.5469/neuroint.2020.00255.e1","url":null,"abstract":"","PeriodicalId":19140,"journal":{"name":"Neurointervention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/41/d2/neuroint-2020-00255-e1.PMC8561034.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38831602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unruptured Intracranial Aneurysm: Screening, Prevalence and Risk Factors.","authors":"Bum-Soo Kim","doi":"10.5469/neuroint.2021.00451","DOIUrl":"https://doi.org/10.5469/neuroint.2021.00451","url":null,"abstract":"Subarachnoid hemorrhage (SAH) due to ruptured intracranial aneurysm is life-threatening, and screening for unruptured intracranial aneurysm (UIA) in selected patients and providing treatment before rupture of selected aneurysms are medically and economically beneficial. Therefore, screening for UIA must be tailored to specific populations in order to balance the prevalence and risk of UIA, cost-effectiveness of screening tests, and the availability of effective and safe treatment. Of these, estimating the prevalence and risk factor of UIA by epidemiological study is methodologically challenging, requiring an optimal cohort for prospective studies with a large amount of data. In the last issue, Kim and colleagues evaluated the prevalence (3.77%) and risk factors (female predominance and hypertension) of UIAs from healthy individuals who underwent brain magnetic resonance angiography using 3T magnetic resonance imaging as part of a routine health examination. There have been several other studies evaluating the prevalence and risk factors of UIA in the literature. The studies were variable with regards to the population studied, indication for imaging, and method of detection (Table 1). The reported prevalence of UIA in the literature ranged 1.8–8.8%, and was 3.2% according to combined results from a systematic review and meta-analyses, which was also similar to the result (3.77%) from Kim et al. In evaluating the risk factors of UIA, it was more common in women, older age, smokers, patients with hypertension, autosomal dominant polycystic kidney disease (ADPKD), or in individuals with family history of intracranial aneurysm of SAH. Consequently, Korean Clinical Practice Guidelines for UIA currently recommended that UIA should be screened according to the following three categories; 1) patients who have 2 or more first-degree relatives with an intracranial aneurysm; 2) patients with ADPKD; and 3) regular screening tests for new aneurysms for patients previously treated with aneurysmal SAH. Although the current guidelines do not support widespread screening for intracranial aneurysms in the general population, additional screening may be considered in patients with other genetic or medical conditions associated with intracranial aneurysms. Recently, according to the data from Korean National Health Insurance Service (NHIS), the number of treatments for UIA has increased because of the increased detection rate as well as increase in number of hospitals capable Correspondence to: Bum-soo Kim, MD Department of Radiology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Korea Tel: +82-2-2258-9639 Fax: +82-2-599-6771 E-mail: bkim.neurorad@gmail.com","PeriodicalId":19140,"journal":{"name":"Neurointervention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/9d/neuroint-2021-00451.PMC8561037.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39551049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monitoring Radiation Doses during Diagnostic and Therapeutic Neurointerventional Procedures: Multicenter Study for Establishment of Reference Levels.","authors":"Yon-Kwon Ihn,&nbsp;Bum-Soo Kim,&nbsp;Hae Woong Jeong,&nbsp;Sang Hyun Suh,&nbsp;Yoo Dong Won,&nbsp;Young-Jun Lee,&nbsp;Dong Joon Kim,&nbsp;Pyong Jeon,&nbsp;Chang-Woo Ryu,&nbsp;Sang-Il Suh,&nbsp;Dae Seob Choi,&nbsp;See Sung Choi,&nbsp;Sang Heum Kim,&nbsp;Jun Soo Byun,&nbsp;Jieun Rho,&nbsp;Yunsun Song,&nbsp;Woo Sang Jeong,&nbsp;Noah Hong,&nbsp;Sung Hyun Baik,&nbsp;Jeong Jin Park,&nbsp;Soo Mee Lim,&nbsp;Jung-Jae Kim,&nbsp;Woong Yoon","doi":"10.5469/neuroint.2021.00437","DOIUrl":"https://doi.org/10.5469/neuroint.2021.00437","url":null,"abstract":"Purpose To assess patient radiation doses during diagnostic and therapeutic neurointerventional procedures from multiple centers and propose dose reference level (RL). Materials and Methods Consecutive neurointerventional procedures, performed in 22 hospitals from December 2020 to June 2021, were retrospectively studied. We collected data from a sample of 429 diagnostic and 731 therapeutic procedures. Parameters including dose-area product (DAP), cumulative air kerma (CAK), fluoroscopic time (FT), and total number of image frames (NI) were obtained. RL were calculated as the 3rd quartiles of the distribution. Results Analysis of 1160 procedures from 22 hospitals confirmed the large variability in patient dose for similar procedures. RLs in terms of DAP, CAK, FT, and NI were 101.6 Gy·cm2, 711.3 mGy, 13.3 minutes, and 637 frames for cerebral angiography, 199.9 Gy·cm2, 3,458.7 mGy, 57.3 minutes, and 1,000 frames for aneurysm coiling, 225.1 Gy·cm2, 1,590 mGy, 44.7 minutes, and 800 frames for stroke thrombolysis, 412.3 Gy·cm2, 4,447.8 mGy, 99.3 minutes, and 1,621.3 frames for arteriovenous malformation (AVM) embolization, respectively. For all procedures, the results were comparable to most of those already published. Statistical analysis showed male and presence of procedural complications were significant factors in aneurysmal coiling. Male, number of passages, and procedural combined technique were significant factors in stroke thrombolysis. In AVM embolization, a significantly higher radiation dose was found in the definitive endovascular cure group. Conclusion Various RLs introduced in this study promote the optimization of patient doses in diagnostic and therapeutic interventional neuroradiology procedures. Proposed 3rd quartile DAP (Gy·cm2) values were 101.6 for diagnostic cerebral angiography, 199.9 for aneurysm coiling, 225.1 for stroke thrombolysis, and 412.3 for AVM embolization. Continual evolution of practices and technologies requires regular updates of RLs.","PeriodicalId":19140,"journal":{"name":"Neurointervention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/28/2f/neuroint-2021-00437.PMC8561028.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39556453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Embolization Tactics of Spinal Epidural Arteriovenous Fistulas.","authors":"Abdulrahman Hamad Al-Abdulwahhab,&nbsp;Yunsun Song,&nbsp;Boseong Kwon,&nbsp;Dae Chul Suh","doi":"10.5469/neuroint.2021.00220","DOIUrl":"https://doi.org/10.5469/neuroint.2021.00220","url":null,"abstract":"<p><strong>Purpose: </strong>Spinal epidural arteriovenous fistulas (SEDAVFs) show an epidural venous sac often with venous congestive myelopathy (VCM) due to intradural reflux at a remote level to which a transarterial approach would be difficult. We present 12 cases of SEDAVF with VCM and describe 3 main tactics for effective transarterial embolization.</p><p><strong>Materials and methods: </strong>Among 152 patients with spinal vascular malformations diagnosed in our tertiary hospital between 1993 and 2019, 12 SEDAVF patients with VCM were included. Three different transarterial embolization tactics were applied according to the vascular configuration and microcatheter accessibility. We evaluated treatment results and clinical outcomes before and after treatment.</p><p><strong>Results: </strong>Transarterial embolization with glue (20-30%) was performed in all patients. The embolization tactics applied in 12 patients were preferential flow (n=2), plug-and-push (n=6), and filling of the venous sac (n=4). Total occlusion of the SEDAVF, including intradural reflux, was achieved in 11 (91.7%) of 12 patients, and partial occlusion was achieved in 1 patient. No periprocedural complications were reported. Spinal cord edema was improved in all patients for an average of 18 months after treatment. Clinical functional outcome in terms of the pain, sensory, motor, and sphincter scale and modified Rankin scores improved during a mean 25-month follow-up (6.3 vs. 3.3, P=0.002; 3.6 vs. 2.3, P=0.002, respectively).</p><p><strong>Conclusion: </strong>Endovascular treatment for 12 SEDAVF patients with VCM achieved a total occlusion rate of 91.7% without any periprocedural complication. The combined embolization tactics can block intradural reflux causing VCM, resulting in overall good clinical outcomes.</p>","PeriodicalId":19140,"journal":{"name":"Neurointervention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c9/b0/neuroint-2021-00220.PMC8561027.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39337367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct Superior Ophthalmic Vein Approach to Treat Anterior Condylar Confluence Dural Arteriovenous Fistula.","authors":"Rasmiranjan Padhi,&nbsp;Sathish Kandasamy,&nbsp;Balasenthil Kumaran,&nbsp;Naci Kocer,&nbsp;Harshith Karmadhari","doi":"10.5469/neuroint.2021.00367","DOIUrl":"https://doi.org/10.5469/neuroint.2021.00367","url":null,"abstract":"<p><p>Dural arteriovenous fistulas (DAVFs) are acquired pathological arteriovenous connections involving vessels that usually supply the meninges. A DAVF in the region of the hypoglossal canal is a rare form of fistula that involves the anterior condylar confluence or anterior condylar vein. We report a case of hypoglossal canal DAVF that was successfully embolized transvenously through a superior ophthalmic vein (SOV) approach. After failed attempts through jugular access, our patient was treated by a unique percutaneous direct puncture approach through the SOV, achieving complete obliteration of the fistula. A step-by-step description of the endovascular technique was described. The clinical course was uneventful without any new neurologic deficit. The eye symptoms and third nerve palsy had completely resolved at the 3-month follow-up visit. Hypoglossal canal DAVFs are rare and may exhibit complex venous drainage patterns. Knowledge of the complex venous anatomy is essential for planning an alternative transvenous route if the standard approach is not feasible. Xper CT (Philips Healthcare, Best, The Netherlands) is an excellent tool for identifying the exact site of the fistula as well as for confirming a safe position of the catheter tip for successful occlusion of this complex dural AV fistula.</p>","PeriodicalId":19140,"journal":{"name":"Neurointervention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ed/63/neuroint-2021-00367.PMC8561036.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39554243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PulseRider Treated Aneurysm with Significant Artifact on Postoperative Magnetic Resonance Angiography: A Case Report and Literature Review.","authors":"Anthony V Nguyen,&nbsp;Laura K Reed,&nbsp;Walter S Lesley","doi":"10.5469/neuroint.2021.00241","DOIUrl":"https://doi.org/10.5469/neuroint.2021.00241","url":null,"abstract":"<p><p>The PulseRider is a neuroendovascular adjunct for wide-necked intracranial aneurysms. The decreased metal burden of the PulseRider theoretically reduces artifact on radiologic imaging. However, we report here on a case of a patient who underwent PulseRider-assisted stent-coiling of a basilar tip aneurysm. He returned 19 months later for intermittent diplopia and darkening of vision but was neurologically intact on exam. Both contrast-enhanced and time-of-flight magnetic resonance angiography (MRA) demonstrated absence of signal in the basilar artery in the proximal anchors of the PulseRider. Given his lack of reproducible symptoms and high functional status, it is presumed that the imaging reflected artifact and not thrombosis/stenosis. Although the PulseRider is a useful treatment option for wide-necked intracranial aneurysms, the clinician should be aware that even contrast-enhanced MRA can produce artifact that resembles thrombosis/stenosis. Non-angiogram radiologic imaging modalities may be appropriate for evaluation for residual aneurysm but not patency of the parent artery.</p>","PeriodicalId":19140,"journal":{"name":"Neurointervention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9b/cb/neuroint-2021-00241.PMC8561032.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39337365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CaRotid Artery Filtering Technique (CRAFT): A Technique for Carotid Artery Stenting with Intrinsic Embolic Protection.","authors":"Michelle Foo,&nbsp;Yifan Ren,&nbsp;Jay Gajera,&nbsp;Christen D Barras,&nbsp;Hong Kuan Kok,&nbsp;Ashu Jhamb,&nbsp;Hussein Abbouchie,&nbsp;Julian Maingard,&nbsp;Duncan Mark Brooks,&nbsp;Hamed Asadi","doi":"10.5469/neuroint.2021.00353","DOIUrl":"https://doi.org/10.5469/neuroint.2021.00353","url":null,"abstract":"<p><strong>Purpose: </strong>Carotid artery stenting (CAS) is an established treatment for symptomatic carotid artery stenosis as an alternative to carotid endarterectomy. A variety of techniques and devices have been devised to minimise periprocedural stroke risk using either proximal or distal embolic protection. This study presents a method of embolic protection during CAS-the CaRotid Artery Filtering Technique (CRAFT).</p><p><strong>Materials and methods: </strong>The CRAFT technique employs aspects of both proximal and distal embolic protection. The CASPER RX stent (MicroVention, Tustin, CA, USA), which is a double-layered, closed-cell, micromesh nitinol stent, is deployed across the carotid artery stenosis with the assistance of a FlowGate balloon guide catheter (Stryker Neurovascular, Fremont, CA, USA). The partially deployed stent acts as a distal filter while the balloon guide is deflated midway during stent deployment to prevent distal plaque embolisation, followed by completion of stent deployment and angioplasty.</p><p><strong>Results: </strong>A total of 94 patients underwent CAS using the CRAFT technique between June 2016 and March 2021. Successful stent deployment was achieved in all patients. Preliminary results demonstrated acute stent occlusion in 6 patients (6.4%) and distal embolic stroke in 5 patients (5.3%). The median procedural fluoroscopy time was 34 minutes with an interquartile range of 22 to 55 minutes.</p><p><strong>Conclusion: </strong>The CRAFT technique of CAS presented by this study can be applied in the treatment of symptomatic carotid artery stenosis in both emergency and elective procedure settings with a high technical success and low distal embolic stroke risk.</p>","PeriodicalId":19140,"journal":{"name":"Neurointervention","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/58/59/neuroint-2021-00353.PMC8561041.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39551048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}