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Single-molecule FRET for probing nanoscale biomolecular dynamics 用于探测纳米级生物分子动力学的单分子 FRET
IF 38.5 1区 物理与天体物理
Nature Reviews Physics Pub Date : 2024-09-12 DOI: 10.1038/s42254-024-00748-7
Daniel Nettels, Nicola Galvanetto, Miloš T. Ivanović, Mark Nüesch, Tianjin Yang, Benjamin Schuler
{"title":"Single-molecule FRET for probing nanoscale biomolecular dynamics","authors":"Daniel Nettels, Nicola Galvanetto, Miloš T. Ivanović, Mark Nüesch, Tianjin Yang, Benjamin Schuler","doi":"10.1038/s42254-024-00748-7","DOIUrl":"https://doi.org/10.1038/s42254-024-00748-7","url":null,"abstract":"<p>Single-molecule spectroscopy is a powerful method for studying the physics of molecular systems, particularly biomolecules, such as proteins and nucleic acids. By avoiding ensemble averaging, single-molecule techniques can resolve structural distributions and fluctuations even for complex and conformationally heterogeneous systems; they also reveal the close link between biological function and the statistical mechanics of the underlying processes. The combination of single-molecule fluorescence detection with Förster resonance energy transfer has become an essential tool for probing biomolecular dynamics on timescales ranging from nanoseconds to days. This Review briefly outlines the state of the art of single-molecule Förster resonance energy transfer spectroscopy and then highlights some of the most important physics-based developments that are expected to further expand the scope of the technique. Key areas of progress include improved time resolution, access to nonequilibrium dynamics and synergies with advances in data analysis and simulations. These developments create new opportunities for attaining a comprehensive understanding of the dynamics and functional mechanisms of biological processes at the nanoscale.</p>","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":null,"pages":null},"PeriodicalIF":38.5,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142204023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mapping the landscape for graphene commercialization 描绘石墨烯商业化前景
IF 38.5 1区 物理与天体物理
Nature Reviews Physics Pub Date : 2024-09-09 DOI: 10.1038/s42254-024-00754-9
Terrance Barkan, Chirag R. Ratwani, Dexter Johnson, Kishan Thodkar, Cary Hill
{"title":"Mapping the landscape for graphene commercialization","authors":"Terrance Barkan, Chirag R. Ratwani, Dexter Johnson, Kishan Thodkar, Cary Hill","doi":"10.1038/s42254-024-00754-9","DOIUrl":"https://doi.org/10.1038/s42254-024-00754-9","url":null,"abstract":"20 years on from the isolation of graphene, over 150,000 graphene-related patents have been filed. Yet despite early promises of integration into semiconducting and photonic devices, the biggest applications to date have been in energy storage and polymers. This article analyses graphene commercialization over the past two decades and discusses the role of graphene in applications towards net-zero carbon.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":null,"pages":null},"PeriodicalIF":38.5,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142204024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A model for changing land use 改变土地用途的模式
IF 44.8 1区 物理与天体物理
Nature Reviews Physics Pub Date : 2024-09-05 DOI: 10.1038/s42254-024-00761-w
Zoe Budrikis
{"title":"A model for changing land use","authors":"Zoe Budrikis","doi":"10.1038/s42254-024-00761-w","DOIUrl":"10.1038/s42254-024-00761-w","url":null,"abstract":"A paper in Royal Society Open Science presents an Ising-like model to describe changes in land use.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":null,"pages":null},"PeriodicalIF":44.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142137885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Farewells and hellos at Nature Reviews Physics 自然-物理评论》的告别与再见
IF 44.8 1区 物理与天体物理
Nature Reviews Physics Pub Date : 2024-09-05 DOI: 10.1038/s42254-024-00759-4
{"title":"Farewells and hellos at Nature Reviews Physics","authors":"","doi":"10.1038/s42254-024-00759-4","DOIUrl":"10.1038/s42254-024-00759-4","url":null,"abstract":"This month, we say farewell to our founding Chief Editor, Iulia Georgescu and greet our new Chief Editor, Nina Meinzer. We also thank our first Advisory Board members (2023–2024) and welcome our next Advisory Board.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":null,"pages":null},"PeriodicalIF":44.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s42254-024-00759-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142137892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
100 years of the Ising model 伊辛模型 100 年
IF 44.8 1区 物理与天体物理
Nature Reviews Physics Pub Date : 2024-09-05 DOI: 10.1038/s42254-024-00760-x
Zoe Budrikis
{"title":"100 years of the Ising model","authors":"Zoe Budrikis","doi":"10.1038/s42254-024-00760-x","DOIUrl":"10.1038/s42254-024-00760-x","url":null,"abstract":"In 1924, Ernst Ising thought he showed a simple model for ferromagnetism couldn''t work. 100 years later, that model, now named for him, is used across all of physics.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":null,"pages":null},"PeriodicalIF":44.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142137872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ising-like model predicts close elections 类等效应模型预测选举结果接近
IF 44.8 1区 物理与天体物理
Nature Reviews Physics Pub Date : 2024-09-05 DOI: 10.1038/s42254-024-00753-w
Zoe Budrikis
{"title":"Ising-like model predicts close elections","authors":"Zoe Budrikis","doi":"10.1038/s42254-024-00753-w","DOIUrl":"10.1038/s42254-024-00753-w","url":null,"abstract":"A model of voters, based on the Ising model, gives an explanation for why elections are often so close.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":null,"pages":null},"PeriodicalIF":44.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142137906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A fully connected Ising machine using standard technology 采用标准技术的全连接伊辛机床
IF 44.8 1区 物理与天体物理
Nature Reviews Physics Pub Date : 2024-09-05 DOI: 10.1038/s42254-024-00757-6
Zoe Budrikis
{"title":"A fully connected Ising machine using standard technology","authors":"Zoe Budrikis","doi":"10.1038/s42254-024-00757-6","DOIUrl":"10.1038/s42254-024-00757-6","url":null,"abstract":"A paper in Nature Electronics reports a proof-of-concept Ising machine with all-to-all connectivity.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":null,"pages":null},"PeriodicalIF":44.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142137882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measuring interactions in a circadian clock 测量昼夜节律时钟中的相互作用
IF 44.8 1区 物理与天体物理
Nature Reviews Physics Pub Date : 2024-09-05 DOI: 10.1038/s42254-024-00755-8
Zoe Budrikis
{"title":"Measuring interactions in a circadian clock","authors":"Zoe Budrikis","doi":"10.1038/s42254-024-00755-8","DOIUrl":"10.1038/s42254-024-00755-8","url":null,"abstract":"An article in Nature Communications uses an Ising-like model to determine the interactions between monomers in a component of the cyanobacterial circadian clock.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":null,"pages":null},"PeriodicalIF":44.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142137873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergent U(1) lattice gauge theory in Rydberg atom arrays 雷德贝格原子阵列中的新兴 U(1) 格规理论
IF 44.8 1区 物理与天体物理
Nature Reviews Physics Pub Date : 2024-08-27 DOI: 10.1038/s42254-024-00749-6
Yanting Cheng, Hui Zhai
{"title":"Emergent U(1) lattice gauge theory in Rydberg atom arrays","authors":"Yanting Cheng,&nbsp;Hui Zhai","doi":"10.1038/s42254-024-00749-6","DOIUrl":"10.1038/s42254-024-00749-6","url":null,"abstract":"Rydberg atom arrays have emerged as a novel platform exhibiting rich quantum many-body physics and offering promise for universal quantum computation. The Rydberg blockade effect plays an essential role in establishing many-body correlations in this system. Over the past 2 or 3 years, Rydberg arrays have been used to realize exotic ground states such as spin liquids, quantum many-body scar states violating quantum thermalization, and a confinement–deconfinement transition through quantum dynamics. In this Perspective, we use lattice gauge theory as a universal theoretical framework to describe the Rydberg blockade effect and the recent exciting developments in this system from equilibrium phases to quantum dynamics. Analysing Rydberg atom arrays through this theoretical framework can reveal their connection with other strongly correlated systems, such as the Fermi–Hubbard model and the lattice gauge model, which can inspire the discovery of new phenomena in this platform. The Rydberg atomic array is an emerging quantum many-body physics platform, exhibiting rich physical phenomena, such as quantum spin liquids and quantum scar states. This Perspective analyses the latest progress in this system through a unified theoretical framework — lattice gauge theory — providing new insights for quantum simulation.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":null,"pages":null},"PeriodicalIF":44.8,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142137907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The co-evolution of computational physics and high-performance computing 计算物理学与高性能计算的共同发展
IF 38.5 1区 物理与天体物理
Nature Reviews Physics Pub Date : 2024-08-23 DOI: 10.1038/s42254-024-00750-z
Jack Dongarra, David Keyes
{"title":"The co-evolution of computational physics and high-performance computing","authors":"Jack Dongarra, David Keyes","doi":"10.1038/s42254-024-00750-z","DOIUrl":"https://doi.org/10.1038/s42254-024-00750-z","url":null,"abstract":"<p>High-performance computational physics has been instrumental in advancing scientific research by regularly providing breakthroughs in speed, accuracy and modelling fidelity. This Perspective highlights the contributions of physicists to the development of high-performance computing infrastructure, algorithms and applications from the early days of computing to the exascale era. We recall the pioneering work of Fermi and von Neumann, who set directions and laid foundations for computational science and examine the ongoing impact of physicists in overcoming current challenges in high-performance computing, such as energy consumption and data storage. As we celebrate milestones such as exascale computing and generative artificial intelligence, it is inspiring to recognize the enduring influence of physicists in driving technological innovations and ensuring the future progress of computational science.</p>","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":null,"pages":null},"PeriodicalIF":38.5,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142204169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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