{"title":"本邦健康成人集団における検診時前立腺特異抗原(PSA)スクリーニング検査に関する検討(第1報) : 健康成人集団におけるPSA陽性率と前立腺がん検出率","authors":"公宏 草場, 逸馬 鴨井, 淳 田北, 信夫 高橋, 一徳 森田, 昌隆 庄田","doi":"10.11320/ningendock.27.23","DOIUrl":"https://doi.org/10.11320/ningendock.27.23","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129672994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of Customer Satisfaction with Ningen Dock Health Check-ups","authors":"T. Shiga, Y. Moriyoshi","doi":"10.11320/NINGENDOCK.27.103","DOIUrl":"https://doi.org/10.11320/NINGENDOCK.27.103","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114912798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trend of Incidence in Positive Cervical Smears from 2002-2010 in Ningen Dock, a Special Japanese Health Check-up System","authors":"A. Imai, K. Matsunami, H. Takagi, S. Ichigo","doi":"10.11320/NINGENDOCK.26.923","DOIUrl":"https://doi.org/10.11320/NINGENDOCK.26.923","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122607550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"指定発言:“テーラーメードの人間ドック健診”の確立をめざして","authors":"清明 渡辺","doi":"10.11320/NINGENDOCK.26.795","DOIUrl":"https://doi.org/10.11320/NINGENDOCK.26.795","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124141602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuki Ohmoto‐Sekine, M. Ishihara, K. Amakawa, Hsieh Shiun Dong, M. Hashimoto, C. Okuda, Hisahito Kato, Kyoko Ogawa, M. Tanabe, S. Hara, Takashi Yamamoto, H. Tsuji, Y. Arase
{"title":"A Case of Acquired Immunodeficiency Syndrome with Pneumocystis Carinii Pneumonia Detected in Health Check-up","authors":"Yuki Ohmoto‐Sekine, M. Ishihara, K. Amakawa, Hsieh Shiun Dong, M. Hashimoto, C. Okuda, Hisahito Kato, Kyoko Ogawa, M. Tanabe, S. Hara, Takashi Yamamoto, H. Tsuji, Y. Arase","doi":"10.11320/NINGENDOCK.26.959","DOIUrl":"https://doi.org/10.11320/NINGENDOCK.26.959","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128161927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of \"AminoIndex Technology\" for Cancer Screening","authors":"N. Okamoto","doi":"10.11320/NINGENDOCK.26.911","DOIUrl":"https://doi.org/10.11320/NINGENDOCK.26.911","url":null,"abstract":"Amino acids are usually considered protein subunits or nutrients. However, recent advances in the metabolomics of amino acids and high-throughput analytical techniques have shown that amino acids in the body (e.g. in the blood) can be used as biomarkers for evaluating disease risk or progression and for selecting proper treatment. For example, one study has reported that the risk of developing diabetes mellitus can be predicted from the metabolite profiles of a combination of 3–5 amino acids in the blood1. These new biomarkers, which are derived from combinations of amino acid concentrations, allow prediction of the risk of developing diabetes mellitus even when adjusted for conventional insulin resistance-related indices such as fasting insulin levels, homeostatic model assessment of risk of insulin resistance, and a 75-g oral glucose tolerance test. Amino acid metabolism indices differ from conventional biochemical indices and therefore may be regulated by a different paradigm. I anticipate that further research into amino acid metabolism will provide new information about disease risk and progression. Advances in analytical techniques are among the most important reasons why novel findings concerning amino acid metabolism, such as the ability to predict the risk of developing diabetes, have been reported over the last several years. Plasma amino acid concentrations have conventionally been measured using an amino acid autoanalyzer that combines ionexchange chromatography and a ninhydrin reaction. However, this method is so time-consuming that it has been used only for specific purposes, such as clinical studies with limited blood samples or in the diagnosis of inborn errors of metabolism. Progress From the Department of Epidemiology, Kanagawa Cancer Center, Yokohama, Japan. Address for Reprints : Takahiko Muramatsu, Institute for Innovation, Ajinomoto, Co., Inc., Kawasaki, Japan. 1-1 Suzuki-cho, Kawasaki-ku, Kawasaki, 210-8681, Japan. Tel: +81-44-210-5845; Fax: +81-44-210-5871 E-mail: takahiko_muramatsu@ajinomoto.com Received February 10, 2012 ; Accepted February 10, 2012 Naoyuki Okamoto","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128866773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relationship between Exercise-induced QRS Axis Shift and Multiple Risk Factors for Coronary Heart Disease","authors":"Kuroda Kenji, Ogawa Takanori, K. Shinji, Wakimoto Toshihiro, Seki Akiho, Fujii Masafumi","doi":"10.11320/NINGENDOCK.26.945","DOIUrl":"https://doi.org/10.11320/NINGENDOCK.26.945","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124487387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Obora Akihiro, K. Takao, K. Takahiro, Endo Mio, Miyawaki Kiichiro, Fukuta Nobuhiro, B. Naomi, Hamaguchi Masahide
{"title":"Associations between Bright Pancreas and Features of Metabolic Syndrome","authors":"Obora Akihiro, K. Takao, K. Takahiro, Endo Mio, Miyawaki Kiichiro, Fukuta Nobuhiro, B. Naomi, Hamaguchi Masahide","doi":"10.11320/NINGENDOCK.26.935","DOIUrl":"https://doi.org/10.11320/NINGENDOCK.26.935","url":null,"abstract":"Abdominal ultrasonography can detect increased echogenicity of the pancreas in the health check-ups of disease-free individuals. We previously defined this finding as ʻbright pancreasʼ and reported on its clinical importance1. Marks et al.2 reported that increased pancreatic echogenicity on abdominal ultrasonography might represent a fatty change of the pancreas and suggested that the increased echogenicity, or ʻbright pancreas,ʼ represents fatty pancreas. Bright pancreas is usually accompanied by fatty liver1,3. Also, it is widely recognized that many patients with fatty liver have type 2 diabetes mellitus, dyslipidemia, obesity, and/or hypertension1. Diagnostic criteria4 for metabolic syndrome were established by the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) in 2001, and a close association has been shown between nonalcoholic fatty liver disease (NAFLD) and the metabolic syndrome5-7. However, bright pancreas has not yet been recognized as an abnormal feature of the pancreas, and even when we detect bright pancreas in examinees, no medication is recommended. To assess the etiology of bright pancreas and evaluate its clinical importance, we performed From the 1)Department of Gastroenterology, Murakami Memorial Hospital, Asahi University, 2)Medical Health Check-up Center of Murakami Memorial Hospital, Asahi University, and 3)Immunology Frontier Research Center at Osaka University. Address for Reprints : Akihiro Obora, Department of Gastroenterology, Murakami Memorial Hospital, Asahi University. 3-23 Hashimoto-cho, Gifu 500-8523, Japan. Tel. +81-58-253-8001 Fax. +81-58-253-3299 E-mail. a-obora@murakami.asahi-u.ac.jp Received July 11, 2011 ; Accepted November 2, 2011 Akihiro Obora1,2), Takao Kojima1,2), Takahiro Kato1), Mio Endo1), Kiichiro Miyawaki1), Nobuhiro Fukuta1), Naomi Ban1), Masahide Hamaguchi3)","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131440158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Usefulness of Measuring Serum High-molecular-weight Adiponectin Level by Recently-developed Chemiluminescence Enzyme Immunoassay in Health Check-up","authors":"H. Hirose, H. Kawabe, I. Saito","doi":"10.11320/NINGENDOCK.26.951","DOIUrl":"https://doi.org/10.11320/NINGENDOCK.26.951","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115593823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kiyoko Amir, Mariko Watanabe, M. Yokotsuka, Y. Kobayashi
{"title":"Changes in Serum Fatty Acids and Effects of Metabolic Syndrome Induced by Intermittent Flaxseed-oil Supplementation","authors":"Kiyoko Amir, Mariko Watanabe, M. Yokotsuka, Y. Kobayashi","doi":"10.11320/NINGENDOCK.26.927","DOIUrl":"https://doi.org/10.11320/NINGENDOCK.26.927","url":null,"abstract":"Recently, metabolic syndrome (MetS) and type 2 diabetes have been increasing rapidly1, and improvement of MetS has become a major concern. In Western countries, several studies have been done on the general effect of supplementation in reducing MetS risk factors2,3 and on supplementation of flaxseed-oil4 rich in α-linolenic acid (ALA). Flaxseed-oil is produced from flax seeds and contains 57% ALA5 which is a precursor of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA)6-8. However, few studies have been concerned with the effect of flaxseed-oil supplementation on MetS. The purpose of this study was to investigate changes in serum fatty acids and the effects on risk factors of MetS due to intermittent flaxseed-oil supplementation.","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129087529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}