Sayaka Takeda, Y. Masuda, M. Kurokawa, Ryosuke Matsuoka, Ranko Marushima, M. Hasegawa, Y. Homma
{"title":"Effects of Mayonnaise Containing Plant Sterol on Blood Cholesterol in Borderline or Mildly Hypercholesterolemic Japanese Subjects","authors":"Sayaka Takeda, Y. Masuda, M. Kurokawa, Ryosuke Matsuoka, Ranko Marushima, M. Hasegawa, Y. Homma","doi":"10.11320/NINGENDOCK2005.21.29","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.29","url":null,"abstract":"Objective In a placebo-controlled, double-blind study, we examined the effects on blood lipids and safety of mayonnaise containing a plant sterol (PS) in Japanese subjects , 40 years and older. Methods Borderline or mildly hypercholesterolemic Japanese subjects (serum total cholesterol (TC)200 mg/dl ; 40 men and 20 women) were randomly divided into two groups and given 15 g of low-energy mayonnaise with 885 mg of PS IPS(+)-groupl or placebo-mayonnaise without PS [PS(-group] daily for 12 weeks. Every 4 weeks, fasting blood was tested and subjective symptoms were analyzed . Results There was no significant change in serum TC and LDL cholesterol (LDL-C) concentrations in the PS(—)-group during the study, while significant decreases were observed in the PS(+)-group at weeks 4, 8, and 12 post-compared with pre-ingestion. Further, changes in the serum apolipoprotein B concentration, as well as serum TC and LDL-C concentrations, in the PS(+)-group were significantly lower compared with those of the PS(—)-group at weeks 4, 8, and 12. There was no change in the serum concentrations of HDL cholesterol (HDL-C) and TG for the PS(+)-group during the study period, and blood tests indicated normal ranges. Conclusion The results indicated that PS-containing low-energy mayonnaise decreased serum TC and LDL-C concentrations in borderline or mildly hypercholesterolemic subjects ; therefore, the mayonnaise may be helpful in maintaining the health of the Japanese population. (Ningen. Dock 2007 ; 21 : 29-34)","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125413050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ningen Dock in Taiwan : Current Status and Future Perspectives","authors":"Ming-Fong Chen","doi":"10.11320/NINGENDOCK2005.21.6_37","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.6_37","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"40 7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116863012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Gotō, N. Nakano, K. Onodera, Shukuko Tanno, Emiko Takahashi, Atsuo Suzuki, Hitomi Takahashi, Yuki Takaide, Emiko Haga, R. Abiko, A. Shimoda, Makoto Kasamatu, Hideharu Komaba, K. Tsunoda
{"title":"Usefulness of Glycated Albumin for Diabetes Screening","authors":"Y. Gotō, N. Nakano, K. Onodera, Shukuko Tanno, Emiko Takahashi, Atsuo Suzuki, Hitomi Takahashi, Yuki Takaide, Emiko Haga, R. Abiko, A. Shimoda, Makoto Kasamatu, Hideharu Komaba, K. Tsunoda","doi":"10.11320/NINGENDOCK2005.21.11","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.11","url":null,"abstract":"Background In recent years, the measurement of glycated albumin (GA) , a glycation product of albumin, h as been used widely in clinical practice in Japan . Since the half-life of albumin is shorter than that of Hb and its rate of glycation is 10 times faster , GA is a more sensitive indicator than HbA lc in evaluating therapeutic effects. An easy-to-use reagent has been developed to measure GA using biochemical analyz ers. Thus, the measurement of GA, conducted in the same panel such as total cholesterol for health examinations, is expected to improve efficiency and reduce costs in primary screening for diabetes mellitus (DM). Methods We measured the serum GA value in 970 subjects receiving comprehensive health examinations to determine the optimal cut-off value of GA for diabetes screening . We also investigated the correlation among GA, fasting plasma glucose (FPG) , and 2h or peak values of the 75 g oral glucose tolerance test (OGTT). The subjects were divided into four groups, i.e., DM group, impaired fasting glycemia (IFG) group, impaired glucose tolerance (IGT) group, and normal glucose tolerance (NGT) group. Results The cut-off value for GA was determined to be 14.5%, at which detection sensitivity for DM was 78.5% and non-DM specificity was 69 .3%. DM and IGT detection sensitivity of GA were similar to those of HbAic. Conclusion We would like to recommend GA for the detection of diabetes together with blood glucose determination. (Ningen Dock 2007 ; 21 : 11 — 13)","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134126521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Albuminuria in General Health Screening in Japan : Relationship with Insulin Resistance and Atherosclerosis","authors":"Y. Ishizaka, N. Ishizaka, M. Yamakado","doi":"10.11320/NINGENDOCK2005.21.51","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.51","url":null,"abstract":"Background and Purpose The presence of microalbuminuria is a risk factor for advanced renal failure and atherosclerotic diseases. In the current study, we investigated the association between albuminuria , insulin resistance, and carotid atherosclerosis. Methods and Results We analyzed data from 3674 individuals (female 1 228 , male 2446) who underwent general health screening. Microalbuminuria was defined as a urine albumin to urine creatinine ratio, termed the albumin excretion index (AEI), of 30 and 299 mg/g ; macroalbuminuria was defined as an AEI >300 mg/g . The prevalence of microand macroalbuminuria was 11.7% and 1.5%, respectively. When compared to the lowest AEI quartile (AEI <4.5 mg/g), the highest AEI quartile (AEI>150 mg/g) was found to be associated with metabolic syndrome (MetS) with an odds ratio of 5.7 (95% CI 1.7-19.3) in women and 3.9 (95% CI 2.9-5.3) in men after adjusting for total cholesterol (TC) and smoking status. In addition, after adjusting for sex, age, TC, smoking status, systolic BP, and fasting glucose, the highest AEI quartile was associated with carotid plaque with an odds ratio of 1.33 (95% CI 1.06-1.67). Conclusion Our data show that the presence of albuminuria in individuals undergoing general health screening, even when it is below the cut-off value for \"micro-\" albuminuria, is a risk factor for MetS and carotid plaque. (Ningen Dock 2007 ; 21 : 51-55)","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131660726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"成功長寿のための抗老化ドック, オキナワ・プログラム","authors":"鈴木 信","doi":"10.11320/NINGENDOCK2005.21.1031","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.1031","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125197496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COPD(慢性閉塞性肺疾患)診断と治療のためのガイドライン","authors":"久道 相澤","doi":"10.11320/NINGENDOCK2005.21.1023","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.1023","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122691913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"健診(検診)における高齢者がんの実態","authors":"修一 三原","doi":"10.11320/NINGENDOCK2005.21.1135","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.1135","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129321376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"「高齢者に対する内視鏡治療(EMR/ESD)の安全性と有用性-胃がん-」","authors":"大三 斉藤","doi":"10.11320/NINGENDOCK2005.21.1145","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.1145","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133365027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"「Key Note Lecture― 本邦の診断基準」","authors":"島本 和明","doi":"10.11320/NINGENDOCK2005.21.1098A","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.1098A","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129667320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"生活習慣病の予防・改善のための運動療法―ベンチステツプ運動を用いた無作為化比較試験","authors":"英彦 山本, 麻衣 武友, 宏暁 田中, 吉田 るみ子, 誠 萱嶋, 敦子 小野, 省一 名取, 照人 橋口, 征郎 丸山","doi":"10.11320/NINGENDOCK2005.21.854","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.854","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124354035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}