{"title":"Fluoro-deoxy-glucose-Positron Emission Tomographyがん検診により発見された悪性リンパ腫5例の検討","authors":"毅 吉田, マミ 北川, 暉人 古賀, 尚志 小林, 礼次 落合, 研 小野","doi":"10.11320/NINGENDOCK2005.22.19","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.22.19","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121222284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"非アルコール性脂肪肝における高脂血症,高血圧,空腹時高血糖の合併とインスリン抵抗性の検討","authors":"悦子 磯野, 嗣彦 泉, 潤子 西田, 理絵 荒木, 和子 望月, 陽 吉村, 市川 健一郎, 祥行 西山, 恭嗣 万代","doi":"10.11320/NINGENDOCK2005.22.46","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.22.46","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126943931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Kato, Lukui Chen, H. Sano, Sadayoshi Watanabe, M. Yoneda, M. Hayakawa, A. Sadato, K. Irie, M. Negoro, T. Kanno
{"title":"Combined Microsurgical and Endovascular Modalities for Complex Intracranial Aneurysms","authors":"Y. Kato, Lukui Chen, H. Sano, Sadayoshi Watanabe, M. Yoneda, M. Hayakawa, A. Sadato, K. Irie, M. Negoro, T. Kanno","doi":"10.11320/NINGENDOCK2005.21.5","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.5","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115628178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Local Differences in Japanese Children's Physical Development Over 55 Years Using Body Mass Index Cross-Sectional Analysis","authors":"E. Sakihara, Rie Kinjo, Tatsuya Tamashiro, Junko Inoha, Emiko Goya, Haruka Uehara","doi":"10.11320/NINGENDOCK2005.21.23","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.23","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127550402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ningen Dock and World Welfare","authors":"H. Akiyama","doi":"10.11320/NINGENDOCK2005.21.1","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.1","url":null,"abstract":"Ningen Dock, our general health check-up system, has a long history. In 1938, one of the leading figures in the Japanese government decided to be hospitalized at the Sakaguchi Internal Medicine Department of the University of Tokyo for a health check-up, in order to dispel a rumor that he had been seriously ill. Journalists likened the hospitalization to a dry dock for ship repair, and the term \"Ningen Dock\" came into being. Later, in 1954, Ningen Dock, or human dry dock practice began to be offered regularly for the first time at The First Tokyo National Hospital and later at St. Luke's International Hospital (current Honorary Chairman of the Board : Shigeaki Hinohara). Since then, a large number of hospitals and medical centers around Japan including those belonging to Japan Hospital Association have followed suit. Ningen Dock programs were originally very expensive and intended mainly for VIPs, but, automatic blood analyzers and other medical testing equipment advanced markedly. Also, after Japan Society of Ningen Dock (current President : Masaharu Nara) was set up in 1959 and expanded, Ningen Dock programs became an established, powerful health management method even for ordinary people around Japan. At present, more than 11 million people have a medical check-up annually using some kind of Ningen Dock service (Fig. 1)1, which contributes to making Japan a nation whose citizens have the longest life expectancy in the world.","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122361484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Significance of Measuring Fasting Immunoreactive Insulin and Homeostasis Model Assessment of Insulin Resistance in Ningen Dock for the Prevention of Lifestyle Related Disease","authors":"T. Fukui","doi":"10.11320/NINGENDOCK2005.21.57","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.57","url":null,"abstract":"Background It has been widely recognized that insulin resistance not only plays an important role in the pathophysiology of diabetes but in all lifestyle related disease that are closely associated with cardiovascular disease. Methods Measurement of fasting immunoreactive insulin (F-IRI) was performed to examine its signifi cance and usefulness as an index of insulin resistance in subjects in Ningen Dock . Results The value of F-IRI increased as the number of risk factors for atherosclerosis increased , and we observed a stronger correlation between the value of F-IRI and BW than the degree of diabetes . We also found that there was a very strong correlation (correlation coefficient exceeding 0 .9) between F-IRI and homeostasis model assessment of insulin resistance (HOMA-IR), which is the index of insulin resistance used most widely at present. Furthermore, we identified that the value of F-IRI changes in correlation with changes in the BW and that visceral fat accumulation is one of the independent factors affecting FIRI. Finally, we examined the effect of lifestyle itself, namely exercise, drinking, and smoking, on the value of F-IRI, and found that exercise and drinking are independent factors associated with F-IRI. Conclusions These results indicate the significance of measuring F-IRI as the most convenient index of insulin resistance, and also indicate its usefulness for the guidance of subjects in Ningen Dock from the viewpoint of the prevention of lifestyle related disease. (Ningen Dock 2007 ; 21 : 57 — 62)","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127955784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Niimi, A. Maeda, M. Shigemoto, R. Misaka, M. Kawana
{"title":"Clinical Significance of Serum p53 Antibodies as a Tumor Screening Marker","authors":"A. Niimi, A. Maeda, M. Shigemoto, R. Misaka, M. Kawana","doi":"10.11320/NINGENDOCK2005.21.15","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.15","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130250897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Nakamura, K. Funatsu, T. Yamashita, E. Miyajima, M. Homma, Kyouko Mouri, Youko Kageyama
{"title":"Clinical Significance of C-Reactive Protein among Japanese for Predicting Atherosclerotic Events","authors":"H. Nakamura, K. Funatsu, T. Yamashita, E. Miyajima, M. Homma, Kyouko Mouri, Youko Kageyama","doi":"10.11320/NINGENDOCK2005.21.41","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.41","url":null,"abstract":"There is growing evidence that local and systemic inflammation plays a role in the initiation and progression of atherosclerosis. Patients with acute coronary syndrome have increased CRP levels before onset . However, the significance of CRP measurement has not been confirmed in healthy Japanese subjects and patients with atherosclerotic diseases . Since 2000, we have started to measure hs-CRP using BN-II (Dade-Behring Co ., IL, USA) in more than 3000 subjects annually. The upper-limit of the normal range of hs-CRP is 1.0 mg/1 in Japanese. Careful consideration is required in interpreting hs-CRP values. Aging, obesity, and smoking increase the values, while weight reduction, and a moderate intake of alcohol reduce the values . The accumulation of numbers with regard to each component of metabolic syndrome indicates the elevation of hs-CRP in a stepwise manner. Patients with arrhythmia such as atrial fibrillation show elevated values. A prospective study on Japanese in the Tokyo area indicated a 22% increase in cardiovascular events in high hs-CRP subjects compared to normal hs-CRP groups. The usefulness of the determination of hsCRP with plasma lipids is confirmed when predicting high-risk subjects. (Ninge;i Dock 2007 ; 21 : 41-45)","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115835713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Carotid Ultrasonography in General Health Screening :Non-Invasive Assessment of Early Atherosclerosis","authors":"N. Ishizaka","doi":"10.11320/NINGENDOCK2005.21.47","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.47","url":null,"abstract":"As carotid ultrasonography is an easy , immediate, and non-invasive diagnosing modality that does not involve radiation exposure, it has gained considerable recognition for use in the screening of carotid atherosclerosis even in asymptomatic subjects . Carotid plaque may be defined when the maximum of the IMT measured at the several arterial segments surpasses a certain cut-off value, and, although not always, has a focal protrusion. The size, number , surface morphology, and echogenicity of such carotid plaque may provide useful information for estimating the likelihood of future ischemic cerebrovascular events. Although significant luminal narrowing ( 70% stenosis) of carotid arteries that may increase the incidence of stroke will rarely be encountered in the setting of Ningen Dock , the presence of carotid atherosclerosis may also indicate an increased likelihood of the presence of coronary artery stenosis or future cardiac events. In addition, visualization of the presence of plaque may also increase the subjects' motivation for making lifestyle modifications, such as smoking cessation . Due to its non-invasive nature, carotid ultrasonography has become reasonable and feasible modality for the diagnosis of early atherosclerosis in the setting of general health screening or Ningen Dock. (Ningen Dock 2007 21 : 47 — 49)","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125489654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kui-cheng Zheng, H. Todoriki, Y. Katsumata, Gao Wei-min, P. Keohavong
{"title":"Analysis of p53 and K-Ras Gene Mutations in Patients with Chronic Bronchitis Using Laser Capture Microdissection Microscope and Mutation Detection","authors":"Kui-cheng Zheng, H. Todoriki, Y. Katsumata, Gao Wei-min, P. Keohavong","doi":"10.11320/NINGENDOCK2005.21.19","DOIUrl":"https://doi.org/10.11320/NINGENDOCK2005.21.19","url":null,"abstract":"","PeriodicalId":189743,"journal":{"name":"Ningen dock : official journal of the Japanese Society of Human Dry Dock","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132395447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}