Netherlands Heart Journal最新文献

{"title":"An old drug, a classic signature.","authors":"Francisco Rodrigues Dos Santos, Mariana Duarte Almeida, Davide Moreira, João Miguel Santos, Inês Fiúza Pires","doi":"10.1007/s12471-026-02064-4","DOIUrl":"10.1007/s12471-026-02064-4","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"323-324"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An old drug, a classic signature.","authors":"Francisco Rodrigues Dos Santos, Mariana Duarte Almeida, Davide Moreira, João Miguel Santos, Inês Fiúza Pires","doi":"10.1007/s12471-026-02065-3","DOIUrl":"10.1007/s12471-026-02065-3","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"325-326"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148584996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optical coherence tomography-guided orbital atherectomy for calcified coronary lesions: rationale and design of the CROWN study.","authors":"Eleni Ntantou, Alexandros A Siskos, Nicolas M van Mieghem, Joost Daemen, Isabella Kardys, Koen Teeuwen, Gioel G Secco, Jan-Malte Sinning, Daniele Forlani, Wijnand K den Dekker","doi":"10.1007/s12471-026-02055-5","DOIUrl":"10.1007/s12471-026-02055-5","url":null,"abstract":"<p><strong>Background: </strong>The Orbital Atherectomy System (OAS) has demonstrated high procedural success, with excellent stent deliverability and low complication rates. The effects of orbital atherectomy (OA) and its impact on calcified coronary plaques are not yet fully understood, highlighting the need for a larger and more comprehensive study.</p><p><strong>Objective: </strong>Calcium Reduction by Orbital Atherectomy in Western Europe (CROWN) is an ongoing study that aims to evaluate the effects of OA in treating de novo, severely calcified coronary lesions before stent placement using optical coherence tomography (OCT), and to assess stent expansion by measuring the OCT-derived minimum stent area (MSA).</p><p><strong>Methods: </strong>The CROWN study is a prospective, multicenter, international, single-arm observational study. We will enroll 100 patients with severely calcified coronary lesions undergoing OCT-guided orbital atherectomy and stent placement. All patients will undergo peri-procedural OCT imaging, with assessments conducted before and after OA, as well as following stent placement. Patients will be enrolled at a maximum of 6 sites in the Netherlands, Germany, and Italy. The primary endpoint is to assess the proportion of patients achieving stent expansion, defined as an OCT-derived MSA ≥ 5.5 mm².</p><p><strong>Conclusion: </strong>The CROWN study will evaluate the impact of OA on calcified plaques, potentially refine operator practices, and provide additional insights on device selection for treating severely calcified lesions (clinicaltrials.gov NCT06035783).</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"299-305"},"PeriodicalIF":2.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When atrial \"smoke\" signals bioprosthetic mitral valve thrombosis.","authors":"Marta Catarina Almeida, Francisco Sampaio, Gustavo Pires-Morais, Bruno Melica, Ricardo Fontes-Carvalho","doi":"10.1007/s12471-026-02070-6","DOIUrl":"https://doi.org/10.1007/s12471-026-02070-6","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148818817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiology in numbers: coronary artery disease in the Netherlands.","authors":"Maaike M Roefs, Giovanni Amoroso, Cyril Camaro, Edgar J Daeter, Maik J Grundeken, Arnoud W J van 't Hof, Robert A F de Lind van Wijngaarden, Erik Lipsic, Martijn Meuwissen, Pim van der Harst, Dennis van Veghel","doi":"10.1007/s12471-026-02058-2","DOIUrl":"10.1007/s12471-026-02058-2","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"283-284"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13376289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148412509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical value of computed tomography in suspected prosthetic valve dysfunction.","authors":"Marco Voortman, Clemens von Birgelen, Daan Ties, Tomasz Plonek, Alexander R van Rosendael, Carine J M Doggen, Lodewijk J Wagenaar","doi":"10.1007/s12471-026-02052-8","DOIUrl":"10.1007/s12471-026-02052-8","url":null,"abstract":"<p><strong>Background: </strong>Prosthetic valve dysfunction (PVD) is potentially life-threatening, yet often challenging to diagnose. We aimed to determine the negative and positive predictive value (NPV, PPV) of cardiac computed tomography (CT) in clinically suspected PVD.</p><p><strong>Methods: </strong>Consecutive patients with prosthetic heart valves (PHVs), who underwent clinically indicated CT for suspected PVD between January 2017 and June 2024, were retrospectively assessed. CT scans with adequate image quality were evaluated and classified (abnormal: periprosthetic masses; structural valve deterioration (SVD); restricted leaflet motion). Valve-related adverse events and follow-up imaging were assessed to evaluate the diagnostic performance.</p><p><strong>Results: </strong>Of all 64 patients (58.6 ± 16.9 years, 42.2% female), 68.8% had mechanical, 18.8% bioprosthetic, and 12.5% transcatheter PHV. CT findings were normal in 34 (53.1%) patients, with an NPV of 94% for ruling out device-related adverse events within a follow-up of 1 year. Among 30 (46.9%) patients with abnormal CT findings, a periprosthetic mass was identified in 21 (70%), including pannus (n = 10), thrombus (n = 6), vegetations (n = 3). SVD was observed in 2 patients (6.7%). Among 23 patients with mechanical PHVs, 18 (78.3%) exhibited restricted leaflet motion. Surgical interventions confirmed CT abnormalities in 7/10 patients, yielding a 70% PPV.</p><p><strong>Conclusion: </strong>This study is the first to demonstrate the high negative predictive value of CT for ruling out significant PVD-related complications, reinforcing its role as a reliable modality for ruling out major adverse events. While the PPV for identifying underlying PVD pathologies was moderate, CT effectively identified structural abnormalities that required intervention, supporting its clinical usefulness for comprehensive assessment of suspected PVD.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"265-273"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13376089/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148369325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative pericardial effusion on routine echocardiography: A review of incidence, progression, and management : To dissolve or to be resolved.","authors":"Stefan van Dinter, Laurens Wollersheim, Wilson Li, Rogier Donders, Niels van Royen, Hendrik-Jan Dieker, Ad Verhagen","doi":"10.1007/s12471-026-02054-6","DOIUrl":"10.1007/s12471-026-02054-6","url":null,"abstract":"<p><p>Postoperative pericardial effusion (PPE) is a common finding after cardiac surgery, with reported incidences ranging widely from 2% to 85%. While most effusions resolve spontaneously, a subset progresses to cardiac tamponade requiring urgent intervention. This systematic review evaluated the true incidence of PPE and PPE-related reinterventions based on routine echocardiographic screening, and explored temporal evolution, symptomatology, and perioperative risk factors. A comprehensive search of Embase, PubMed, and Web of Science through May 2025 identified 26 eligible studies including 8,495 patients. Data extraction followed PRISMA guidelines and quality assessment with the JBI checklist. Random-effects meta-analysis demonstrated a pooled PPE incidence of 36% (95% confidence interval (CI) 25-49%), whereas only 3% (95% CI 2-4%) required reintervention, ranging from 2% after CABG to 6% after aortic surgery. Large effusions (> 2 cm) were associated with a substantially higher likelihood of intervention (54% [14-90%]), although spontaneous resolution remained common. Preventive strategies such as posterior pericardiotomy and posterior chest tube placement significantly reduced both PPE incidence and reintervention rates. Despite these findings, interpretation is limited by substantial heterogeneity in study design, definitions, and follow-up protocols. Standardized definitions, structured echocardiographic follow-up, and prospective studies are needed to improve risk stratification and guide clinical decision-making.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"254-264"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148163656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinician-assessed NYHA and EHRA symptom classifications only moderately reflect patient-reported quality of life in heart failure and atrial fibrillation.","authors":"Jeroen A A van de Pol, Frederique J Hafkamp, Pepijn H van der Voort, Johannes C Post, Sylvie F A M S de Jong, Monica Monroy, Sabine C M Eijsbouts, Ruud F Spee, Arjen R T van de Ven, Boudewijn Klop","doi":"10.1007/s12471-026-02051-9","DOIUrl":"10.1007/s12471-026-02051-9","url":null,"abstract":"<p><strong>Background: </strong>Clinician-assessed symptoms are expected to agree with patient-perceived symptoms. However, patients may value the impact of symptoms on their health-related quality of life (HRQoL) differently from clinicians. This study aimed to evaluate the relationship between patient-perceived HRQoL and clinician-assessed symptom severity in patients with Heart Failure (HF) and Atrial Fibrillation (AF).</p><p><strong>Methods: </strong>Newly diagnosed HF and AF patients were prospectively included. Information on symptoms and HRQoL was collected at diagnosis and after 12 months during routine HF- and AF-outpatient clinic visits. Symptom severity was assessed by clinicians using the NYHA classification for HF and EHRA score for AF. HRQoL was assessed using the CaReQol-CHF (HF) and AFEQT (AF).</p><p><strong>Results: </strong>Complete baseline and 12-month follow-up information was available for 254 HF patients and 765 AF patients. Moderate correlations were observed between NYHA classification and CaReQoL-CHF at diagnosis and follow-up (Spearman's ρ: HF_social: 0.202 and 0.426, HF_physical: 0.317 and 0.421, respectively), and between EHRA score and AFEQT (Spearman's ρ: -0.363 and -0.305). Clinician-assessed improvement in HF or AF symptoms from diagnosis to 12 months was associated with patient-reported improvement in HRQoL (HF_social: F(250.2) = 3.11, p < 0.046; HF_physical: F(251.2) = 11.19, p < 0.001; and AF: F(762.2) = 25.86, p < 0.001). When clinicians reported unchanged or worsening symptoms, no significant HRQoL changes were reported by patients.</p><p><strong>Conclusion: </strong>Clinician-assessed symptoms correlate moderately with patient-reported HRQoL, with large inter-individual variation in HRQoL. NYHA and EHRA classifications may not accurately reflect patient-perceived burden of disease over time. Incorporating patient-reported outcomes into routine care may better guide treatment, improve the identification of patients' needs, and support informed clinical and shared decision-making.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"274-282"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148397496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breaking free: Lung herniation following epicardial lead placement.","authors":"Mariana Pereira Santos, David Sá-Couto, Diana Ribeiro, Maria João Sousa, Vítor Monteiro, Victor Sanfins, Catarina Gomes, Patrícia Rodrigues","doi":"10.1007/s12471-026-02053-7","DOIUrl":"10.1007/s12471-026-02053-7","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"285-286"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147931617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introducing cardiology in numbers.","authors":"Pim van der Harst","doi":"10.1007/s12471-026-02060-8","DOIUrl":"10.1007/s12471-026-02060-8","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"243"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13376316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148430123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}