Jeroen A A van de Pol, Frederique J Hafkamp, Pepijn H van der Voort, Johannes C Post, Sylvie F A M S de Jong, Monica Monroy, Sabine C M Eijsbouts, Ruud F Spee, Arjen R T van de Ven, Boudewijn Klop
{"title":"Clinician-assessed NYHA and EHRA symptom classifications only moderately reflect patient-reported quality of life in heart failure and atrial fibrillation.","authors":"Jeroen A A van de Pol, Frederique J Hafkamp, Pepijn H van der Voort, Johannes C Post, Sylvie F A M S de Jong, Monica Monroy, Sabine C M Eijsbouts, Ruud F Spee, Arjen R T van de Ven, Boudewijn Klop","doi":"10.1007/s12471-026-02051-9","DOIUrl":"10.1007/s12471-026-02051-9","url":null,"abstract":"<p><strong>Background: </strong>Clinician-assessed symptoms are expected to agree with patient-perceived symptoms. However, patients may value the impact of symptoms on their health-related quality of life (HRQoL) differently from clinicians. This study aimed to evaluate the relationship between patient-perceived HRQoL and clinician-assessed symptom severity in patients with Heart Failure (HF) and Atrial Fibrillation (AF).</p><p><strong>Methods: </strong>Newly diagnosed HF and AF patients were prospectively included. Information on symptoms and HRQoL was collected at diagnosis and after 12 months during routine HF- and AF-outpatient clinic visits. Symptom severity was assessed by clinicians using the NYHA classification for HF and EHRA score for AF. HRQoL was assessed using the CaReQol-CHF (HF) and AFEQT (AF).</p><p><strong>Results: </strong>Complete baseline and 12-month follow-up information was available for 254 HF patients and 765 AF patients. Moderate correlations were observed between NYHA classification and CaReQoL-CHF at diagnosis and follow-up (Spearman's ρ: HF<sub>social</sub>: 0.202 and 0.426, HF<sub>physical</sub>: 0.317 and 0.421, respectively), and between EHRA score and AFEQT (Spearman's ρ: -0.363 and -0.305). Clinician-assessed improvement in HF or AF symptoms from diagnosis to 12 months was associated with patient-reported improvement in HRQoL (HF<sub>social</sub>: F(250.2) = 3.11, p < 0.046; HF<sub>physical</sub>: F(251.2) = 11.19, p < 0.001; and AF: F(762.2) = 25.86, p < 0.001). When clinicians reported unchanged or worsening symptoms, no significant HRQoL changes were reported by patients.</p><p><strong>Conclusion: </strong>Clinician-assessed symptoms correlate moderately with patient-reported HRQoL, with large inter-individual variation in HRQoL. NYHA and EHRA classifications may not accurately reflect patient-perceived burden of disease over time. Incorporating patient-reported outcomes into routine care may better guide treatment, improve the identification of patients' needs, and support informed clinical and shared decision-making.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"274-282"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148397496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Voortman, Clemens von Birgelen, Daan Ties, Tomasz Plonek, Alexander R van Rosendael, Carine J M Doggen, Lodewijk J Wagenaar
{"title":"Clinical value of computed tomography in suspected prosthetic valve dysfunction.","authors":"Marco Voortman, Clemens von Birgelen, Daan Ties, Tomasz Plonek, Alexander R van Rosendael, Carine J M Doggen, Lodewijk J Wagenaar","doi":"10.1007/s12471-026-02052-8","DOIUrl":"10.1007/s12471-026-02052-8","url":null,"abstract":"<p><strong>Background: </strong>Prosthetic valve dysfunction (PVD) is potentially life-threatening, yet often challenging to diagnose. We aimed to determine the negative and positive predictive value (NPV, PPV) of cardiac computed tomography (CT) in clinically suspected PVD.</p><p><strong>Methods: </strong>Consecutive patients with prosthetic heart valves (PHVs), who underwent clinically indicated CT for suspected PVD between January 2017 and June 2024, were retrospectively assessed. CT scans with adequate image quality were evaluated and classified (abnormal: periprosthetic masses; structural valve deterioration (SVD); restricted leaflet motion). Valve-related adverse events and follow-up imaging were assessed to evaluate the diagnostic performance.</p><p><strong>Results: </strong>Of all 64 patients (58.6 ± 16.9 years, 42.2% female), 68.8% had mechanical, 18.8% bioprosthetic, and 12.5% transcatheter PHV. CT findings were normal in 34 (53.1%) patients, with an NPV of 94% for ruling out device-related adverse events within a follow-up of 1 year. Among 30 (46.9%) patients with abnormal CT findings, a periprosthetic mass was identified in 21 (70%), including pannus (n = 10), thrombus (n = 6), vegetations (n = 3). SVD was observed in 2 patients (6.7%). Among 23 patients with mechanical PHVs, 18 (78.3%) exhibited restricted leaflet motion. Surgical interventions confirmed CT abnormalities in 7/10 patients, yielding a 70% PPV.</p><p><strong>Conclusion: </strong>This study is the first to demonstrate the high negative predictive value of CT for ruling out significant PVD-related complications, reinforcing its role as a reliable modality for ruling out major adverse events. While the PPV for identifying underlying PVD pathologies was moderate, CT effectively identified structural abnormalities that required intervention, supporting its clinical usefulness for comprehensive assessment of suspected PVD.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"265-273"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13376089/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148369325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana Pereira Santos, David Sá-Couto, Diana Ribeiro, Maria João Sousa, Vítor Monteiro, Victor Sanfins, Catarina Gomes, Patrícia Rodrigues
{"title":"Breaking free: Lung herniation following epicardial lead placement.","authors":"Mariana Pereira Santos, David Sá-Couto, Diana Ribeiro, Maria João Sousa, Vítor Monteiro, Victor Sanfins, Catarina Gomes, Patrícia Rodrigues","doi":"10.1007/s12471-026-02053-7","DOIUrl":"10.1007/s12471-026-02053-7","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"285-286"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147931617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Introducing cardiology in numbers.","authors":"Pim van der Harst","doi":"10.1007/s12471-026-02060-8","DOIUrl":"10.1007/s12471-026-02060-8","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"243"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13376316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148430123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexander Hirsch, Leo H B Baur, Peter Damman, Marco Guglielmo, Maarten A H van Leeuwen, Sanne Ruigrok, Maik J Grundeken
{"title":"2024 European Society of Cardiology guidelines for the management of chronic coronary syndromes : Statement of endorsement by the NVVC.","authors":"Alexander Hirsch, Leo H B Baur, Peter Damman, Marco Guglielmo, Maarten A H van Leeuwen, Sanne Ruigrok, Maik J Grundeken","doi":"10.1007/s12471-026-02059-1","DOIUrl":"10.1007/s12471-026-02059-1","url":null,"abstract":"<p><p>This article discusses the updated 2024 European Society of Cardiology guidelines on chronic coronary syndromes and situates them within the context of Dutch clinical practice. A working group was appointed by the Netherlands Society of Cardiology (Nederlandse Vereniging voor Cardiologie). It consisted of a general cardiologist, interventional cardiologists, cardiovascular imaging cardiologists, and a representative of the Dutch Heart Foundation (Nederlandse Hartstichting). This document summarizes the key recommendations and includes additional guidance tailored to clinical practice in the Netherlands, focusing on the risk-factor-weighted clinical likelihood model, the choice of non-invasive imaging modality, functional assessment of epicardial artery stenosis during invasive coronary angiography, and angina and ischemia with non-obstructive coronary arteries. It is intended for all healthcare professionals involved in the care of patients with chronic coronary syndromes and has been approved by the Netherlands Society of Cardiology and the Dutch Heart Foundation.</p>","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"244-253"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13376111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148422717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Where is the tachycardia? Cardiac tamponade in severe hypothyroidism.","authors":"Ilire Imeri, Edgard Prihadi","doi":"10.1007/s12471-026-02068-0","DOIUrl":"https://doi.org/10.1007/s12471-026-02068-0","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148536174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beyond the catheter: patient selection and pathways in complex interventional cardiology.","authors":"Pim van der Harst","doi":"10.1007/s12471-026-02056-4","DOIUrl":"10.1007/s12471-026-02056-4","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"199"},"PeriodicalIF":2.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13216354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147974173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Sofia Nogueira Fernandes, Rui Pedro Files Flores, Sérgia Andreia Alves Rodrigues da Rocha Costa
{"title":"Exercise-induced ventricular tachycardia in a young adult: what lies beneath?","authors":"Ana Sofia Nogueira Fernandes, Rui Pedro Files Flores, Sérgia Andreia Alves Rodrigues da Rocha Costa","doi":"10.1007/s12471-026-02037-7","DOIUrl":"10.1007/s12471-026-02037-7","url":null,"abstract":"","PeriodicalId":18952,"journal":{"name":"Netherlands Heart Journal","volume":" ","pages":"236-237"},"PeriodicalIF":2.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13216372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147645720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}