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Netherlands Journal of Medicine最新文献

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Case series of three adult patients with exceptional clinical presentations of haemophagocytic lymphohistiocytosis. 病例系列的三个成人患者的特殊临床表现的噬血细胞淋巴组织细胞增多症。
4区 医学
Netherlands Journal of Medicine Pub Date : 2020-04-01
M Khairoun, F Meynen, W Vercoutere, H L Leavis
{"title":"Case series of three adult patients with exceptional clinical presentations of haemophagocytic lymphohistiocytosis.","authors":"M Khairoun,&nbsp;F Meynen,&nbsp;W Vercoutere,&nbsp;H L Leavis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Macrophage activation syndrome (MAS) is a secondary form of haemophagocytic lymphohistiocytosis (HLH). MAS-HLH is an underrecognised and life-threatening condition associated with a heterogeneous group of diseases including connective tissue disease and inflammatory disorders. Here, we report three cases of adult patients with MAS-HLH triggered by different entities, including systemic lupus erythematosus, Griscelli syndrome type 2, and Adult onset Still's disease.</p>","PeriodicalId":18918,"journal":{"name":"Netherlands Journal of Medicine","volume":"78 3","pages":"136-141"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37869831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Splenic incidentaloma. 经由腹部超音波检查意外发现脾。
4区 医学
Netherlands Journal of Medicine Pub Date : 2020-04-01
H Fujikawa, T Matsushita
{"title":"Splenic incidentaloma.","authors":"H Fujikawa,&nbsp;T Matsushita","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18918,"journal":{"name":"Netherlands Journal of Medicine","volume":"78 3","pages":"142"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37869833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Care for adult non-ICU Covid-19 patients: early experiences from a Belgian tertiary care centre. 成人非icu Covid-19患者的护理:来自比利时三级护理中心的早期经验
4区 医学
Netherlands Journal of Medicine Pub Date : 2020-04-01
K van Halem, J Cox, P Messiaen, K Pat, C Declercq, A Meersman, D Ramaekers, R Cartuyvels, J van der Hilst
{"title":"Care for adult non-ICU Covid-19 patients: early experiences from a Belgian tertiary care centre.","authors":"K van Halem,&nbsp;J Cox,&nbsp;P Messiaen,&nbsp;K Pat,&nbsp;C Declercq,&nbsp;A Meersman,&nbsp;D Ramaekers,&nbsp;R Cartuyvels,&nbsp;J van der Hilst","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The current Covid-19 outbreak poses many challenges on hospital organisation and patient care. Our hospital lies at the epicentre of the Belgian epidemic. On April 1st, a total of 235 Covid-19 patients had been admitted to our hospital. This demanded an unprecedented adaptation of our hospital organisation, and we have met many clinical issues in the care for Covid-19 patients. In this article, we share our experience in the handling of some of the practical and organisational issues in the care for Covid-19 patients.</p>","PeriodicalId":18918,"journal":{"name":"Netherlands Journal of Medicine","volume":"78 3","pages":"111-115"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37869899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FSGS tip lesion in polyautoimmunity including Sjögren's syndrome. 多自身免疫包括Sjögren综合征的FSGS尖端病变。
4区 医学
Netherlands Journal of Medicine Pub Date : 2020-04-01
E A Lucassen, T Vlasveld, N Hommes
{"title":"FSGS tip lesion in polyautoimmunity including Sjögren's syndrome.","authors":"E A Lucassen,&nbsp;T Vlasveld,&nbsp;N Hommes","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We present a case with five auto-immune phenomena, including Sjögren's syndrome, for which we also diagnosed a tip lesion of focal segmental glomerulosclerosis (FSGS).v About one-third of Sjögren's syndrome patients have renal involvement, but FSGS is rarely reported. FSGS is thought to involve T-cell dysfunction and in this patient with multiple auto-immune phenomena, it may reflect a severe dysregulation of cellular immunity.</p>","PeriodicalId":18918,"journal":{"name":"Netherlands Journal of Medicine","volume":"78 3","pages":"133-135"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37869830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Answer to Photo Quiz A mobile abdominal mass. 图片测验的答案一个移动的腹部肿块。
4区 医学
Netherlands Journal of Medicine Pub Date : 2020-04-01
B Mostert, B P L Wijnhoven, J L C M van Saase
{"title":"Answer to Photo Quiz A mobile abdominal mass.","authors":"B Mostert,&nbsp;B P L Wijnhoven,&nbsp;J L C M van Saase","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18918,"journal":{"name":"Netherlands Journal of Medicine","volume":"78 3","pages":"145"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37869836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Answer to Photo Quiz White striae and erosions of the oral mucosa, but it is not oral lichen planus. 口腔黏膜出现白色条纹和糜烂，但不是口腔扁平苔藓。
4区 医学
Netherlands Journal of Medicine Pub Date : 2020-04-01
M Val, M Gobbo, M Rossi, M Ragazzo, L Guarda Nardini
{"title":"Answer to Photo Quiz White striae and erosions of the oral mucosa, but it is not oral lichen planus.","authors":"M Val,&nbsp;M Gobbo,&nbsp;M Rossi,&nbsp;M Ragazzo,&nbsp;L Guarda Nardini","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18918,"journal":{"name":"Netherlands Journal of Medicine","volume":"78 3","pages":"147"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37869839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interbellum. 细胞间。
4区 医学
Netherlands Journal of Medicine Pub Date : 2020-04-01
P L A van Daele
{"title":"Interbellum.","authors":"P L A van Daele","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18918,"journal":{"name":"Netherlands Journal of Medicine","volume":"78 3","pages":"95"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37869892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anaemia: A disease or symptom. 贫血:一种疾病或症状。
4区 医学
Netherlands Journal of Medicine Pub Date : 2020-04-01
D A Newhall, R Oliver, S Lugthart
{"title":"Anaemia: A disease or symptom.","authors":"D A Newhall,&nbsp;R Oliver,&nbsp;S Lugthart","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Anaemia is a common diagnosis for clinicians. This mini-review summarises criteria for diagnosing the cause of anaemia. Within the microcytic anaemias, iron-deficient anaemia is most common. In addition, we would like to raise awareness of thalassaemia as a differential diagnosis. A normocytic anaemia, such as anaemia of chronic disease, is a diagnosis of exclusion. A macrocytic anaemia scheme is provided and differentiates based on reticulocyte count. We aim to provide the readers a clear overview of anaemia and when to refer to haematologists.</p>","PeriodicalId":18918,"journal":{"name":"Netherlands Journal of Medicine","volume":"78 3","pages":"104-110"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37869896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperactive thyroid nodules treated by radiofrequency ablation: a Dutch single-centre experience. 射频消融治疗甲状腺结节过度活跃:荷兰单中心经验。
4区 医学
Netherlands Journal of Medicine Pub Date : 2020-03-01
H de Boer, W Bom, P Veendrick, E Bom, M van Borren, F Joosten
{"title":"Hyperactive thyroid nodules treated by radiofrequency ablation: a Dutch single-centre experience.","authors":"H de Boer,&nbsp;W Bom,&nbsp;P Veendrick,&nbsp;E Bom,&nbsp;M van Borren,&nbsp;F Joosten","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Hyperactive thyroid nodules (HTN) are usually treated with radioactive iodine (RAI). However, as RAI is associated with a 30-60% long-term risk of permanent hypothyroidism, radiofrequency ablation (RFA) may be a good alternative. Primary aim of this study was to assess the percentage of patients achieving euthyroidism after RFA.</p><p><strong>Patients and methods: </strong>Patients with a symptomatic HTN were treated by ultrasound-guided RFA, using the trans-isthmic approach and moving-shot technique, in an outpatient setting under local anaesthesia.</p><p><strong>Results: </strong>Twenty-one patients were included, ranging in age from 37-75 years. Follow-up was at least one year. All patients had a suppressed serum thyroid-stimulating hormone (TSH), with free thyroxine (FT4) and free triiodothyronine (FT3) concentrations mildly elevated in 33% and 43% of cases, respectively. RFA was not associated with clinically meaningful adverse effects. TSH normalisation was achieved in 11/21 patients (52%) after first RFA. A partial response, defined as a normalisation of FT4 and FT3, but incomplete improvement of TSH, was observed in 6/21 patients (29%). Three patients had no response (14%), and one patient developed mild, asymptomatic subclinical hypothyroidism. Five patients underwent a second RFA and this led to TSH normalisation in four, thereby raising the rate of complete remission to 71%. Recurrence of TSH suppression did not occur during the study period.</p><p><strong>Conclusion: </strong>These data suggest that RFA is a safe and promising treatment for symptomatic hyperactive thyroid nodules, with a low risk of permanent hypothyroidism. Long-term studies are needed to identify the recurrence risk of hyperthyroidism.</p>","PeriodicalId":18918,"journal":{"name":"Netherlands Journal of Medicine","volume":"78 2","pages":"64-70"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37869889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Answer to Photo Quiz Raccoon Sign. 浣熊标志图片测试的答案。
4区 医学
Netherlands Journal of Medicine Pub Date : 2020-03-01
M van der Huizen, E Jacobs
{"title":"Answer to Photo Quiz Raccoon Sign.","authors":"M van der Huizen,&nbsp;E Jacobs","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":18918,"journal":{"name":"Netherlands Journal of Medicine","volume":"78 2","pages":"91"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37869895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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