多自身免疫包括Sjögren综合征的FSGS尖端病变。

4区医学 Q3 Medicine

Netherlands Journal of Medicine Pub Date : 2020-04-01

E A Lucassen, T Vlasveld, N Hommes

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引用次数: 0

摘要

我们提出了一个病例，有五种自身免疫现象，包括Sjögren综合征，我们也诊断了局灶节段性肾小球硬化(FSGS)的尖端病变。v大约三分之一的Sjögren综合征患者有肾脏受累，但FSGS很少报道。FSGS被认为与t细胞功能障碍有关，在该患者中存在多种自身免疫现象，可能反映了细胞免疫的严重失调。

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FSGS tip lesion in polyautoimmunity including Sjögren's syndrome.

We present a case with five auto-immune phenomena, including Sjögren's syndrome, for which we also diagnosed a tip lesion of focal segmental glomerulosclerosis (FSGS).v About one-third of Sjögren's syndrome patients have renal involvement, but FSGS is rarely reported. FSGS is thought to involve T-cell dysfunction and in this patient with multiple auto-immune phenomena, it may reflect a severe dysregulation of cellular immunity.

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来源期刊

Netherlands Journal of Medicine 医学-医学：内科

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The Netherlands Journal of Medicine publishes papers in all relevant fields of internal medicine. In addition to reports of original clinical and experimental studies, reviews on topics of interest or importance, case reports, book reviews and letters to the editor are welcomed.