Nature chemistry最新文献_第2页

Protocells by spontaneous reaction of cysteine with short-chain thioesters 半胱氨酸与短链硫酯的自发反应产生原电池

IF 21.8 1区化学

Nature chemistry Pub Date : 2024-10-30 DOI: 10.1038/s41557-024-01666-y

Christy J. Cho, Taeyang An, Yei-Chen Lai, Alberto Vázquez-Salazar, Alessandro Fracassi, Roberto J. Brea, Irene A. Chen, Neal K. Devaraj

{"title":"Protocells by spontaneous reaction of cysteine with short-chain thioesters","authors":"Christy J. Cho, Taeyang An, Yei-Chen Lai, Alberto Vázquez-Salazar, Alessandro Fracassi, Roberto J. Brea, Irene A. Chen, Neal K. Devaraj","doi":"10.1038/s41557-024-01666-y","DOIUrl":"https://doi.org/10.1038/s41557-024-01666-y","url":null,"abstract":"All known forms of life are composed of cells, whose boundaries are defined by lipid membranes that separate and protect cell contents from the environment. It is unknown how the earliest forms of life were compartmentalized. Several models have suggested a role for single-chain lipids such as fatty acids, but the membranes formed are often unstable, particularly when made from shorter alkyl chains (≤C8) that were probably more prevalent on prebiotic Earth. Here we show that the amino acid cysteine can spontaneously react with two short-chain (C8) thioesters to form diacyl lipids, generating protocell-like membrane vesicles. The three-component reaction takes place rapidly in water using low concentrations of reactants. Silica can catalyse the formation of protocells through a simple electrostatic mechanism. Several simple aminothiols react to form diacyl lipids, including short peptides. The protocells formed are compatible with functional ribozymes, suggesting that coupling of multiple short-chain precursors may have provided membrane building blocks during the early evolution of cells.<figure></figure>","PeriodicalId":18909,"journal":{"name":"Nature chemistry","volume":"41 1","pages":""},"PeriodicalIF":21.8,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142541270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Remote chirality transfer in low-dimensional hybrid metal halide semiconductors 低维混合金属卤化物半导体中的远程手性转移

IF 21.8 1区化学

Nature chemistry Pub Date : 2024-10-25 DOI: 10.1038/s41557-024-01662-2

Md Azimul Haque, Andrew Grieder, Steven P. Harvey, Roman Brunecky, Jiselle Y. Ye, Bennett Addison, Junxiang Zhang, Yifan Dong, Yi Xie, Matthew P. Hautzinger, Heshan Hewa Walpitage, Kai Zhu, Jeffrey L. Blackburn, Zeev Valy Vardeny, David B. Mitzi, Joseph J. Berry, Seth R. Marder, Yuan Ping, Matthew C. Beard, Joseph M. Luther

{"title":"Remote chirality transfer in low-dimensional hybrid metal halide semiconductors","authors":"Md Azimul Haque, Andrew Grieder, Steven P. Harvey, Roman Brunecky, Jiselle Y. Ye, Bennett Addison, Junxiang Zhang, Yifan Dong, Yi Xie, Matthew P. Hautzinger, Heshan Hewa Walpitage, Kai Zhu, Jeffrey L. Blackburn, Zeev Valy Vardeny, David B. Mitzi, Joseph J. Berry, Seth R. Marder, Yuan Ping, Matthew C. Beard, Joseph M. Luther","doi":"10.1038/s41557-024-01662-2","DOIUrl":"https://doi.org/10.1038/s41557-024-01662-2","url":null,"abstract":"In hybrid metal halide perovskites, chiroptical properties typically arise from structural symmetry breaking by incorporating a chiral A-site organic cation within the structure, which may limit the compositional space. Here we demonstrate highly efficient remote chirality transfer where chirality is imposed on an otherwise achiral hybrid metal halide semiconductor by a proximal chiral molecule that is not interspersed as part of the structure yet leads to large circular dichroism dissymmetry factors (gCD) of up to 10−2. Density functional theory calculations reveal that the transfer of stereochemical information from the chiral proximal molecule to the inorganic framework is mediated by selective interaction with divalent metal cations. Anchoring of the chiral molecule induces a centro-asymmetric distortion, which is discernible up to four inorganic layers into the metal halide lattice. This concept is broadly applicable to low-dimensional hybrid metal halides with various dimensionalities (1D and 2D) allowing independent control of the composition and degree of chirality.<figure></figure>","PeriodicalId":18909,"journal":{"name":"Nature chemistry","volume":"11 1","pages":""},"PeriodicalIF":21.8,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142489266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Supramolecular crystals for hydrogen storage 用于储氢的超分子晶体

IF 21.8 1区化学

Nature chemistry Pub Date : 2024-10-23 DOI: 10.1038/s41557-024-01661-3

引用次数: 0

The chemical sciences need introverts too 化学科学也需要内向的人

IF 19.2 1区化学

Nature chemistry Pub Date : 2024-10-23 DOI: 10.1038/s41557-024-01657-z

Bruce C. Gibb

引用次数: 0

The original caretakers of salvinorin A and recognizing Indigenous contributions to science 丹参素 A 的原始守护者，承认土著人对科学的贡献

IF 19.2 1区化学