Nature chemistry最新文献_第2页

The radical-radical cross-coupling of alkyl carboxylic acids and organoborons 烷基羧酸与有机硼的自由基-自由基交叉偶联

IF 21.8 1区化学

Nature chemistry Pub Date : 2026-10-05 DOI: 10.1038/s41557-026-02237-z

Jessica Zhong, Maxime Boudjelel, Jake M. Evans, Ian Vanswearingen, Christian A. Malapit

{"title":"The radical-radical cross-coupling of alkyl carboxylic acids and organoborons","authors":"Jessica Zhong, Maxime Boudjelel, Jake M. Evans, Ian Vanswearingen, Christian A. Malapit","doi":"10.1038/s41557-026-02237-z","DOIUrl":"https://doi.org/10.1038/s41557-026-02237-z","url":null,"abstract":"Carbon–carbon bond-forming reactions are fundamental in organic synthesis. Radical–radical cross-coupling stands out as a key strategy for carbon–carbon bond formation, especially for C(sp3)–C(sp3) bonds, to construct complex, three-dimensional, value-added molecules. Existing approaches for direct radical–radical cross-coupling involve a persistent radical and a transient radical to leverage the persistent radical effect. Kolbe electrolysis is one of the few methods that directly cross-couples two transient radicals via electro-oxidative activation of carboxylic acids. However, the direct cross-coupling of transient radicals from two distinct radical precursors, such as carboxylic acids and boronic acids, remains challenging. Here we integrate redox-matched alternating-polarity electrolysis with controlled activation of redox-active species to enable the cross-coupling of alkyl carboxylic acids with alkyl boronic acids. In addition, we demonstrate the synthetic utility and versatility of this transformation by showcasing homocoupling reactions and net carboxylic acid–alkene cross-coupling via in situ alkene hydroboration, as well as tandem processes with Suzuki coupling and Buchwald–Hartwig amination.","PeriodicalId":18909,"journal":{"name":"Nature chemistry","volume":"1 1","pages":""},"PeriodicalIF":21.8,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149087780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A precursor-degassing approach for accessing boron allotropes. 一种获取硼同素异形体的前体脱气方法。

IF 24.5 1区化学

Nature chemistry Pub Date : 2026-10-05 DOI: 10.1038/s41557-026-02281-9

引用次数: 0

A crystalline uranium Fischer-type carbyne 一种结晶铀费雪型碳

IF 21.8 1区化学

Nature chemistry Pub Date : 2026-10-02 DOI: 10.1038/s41557-026-02260-0

John A. Seed, Jhen-Kuei Yu, Florian Meurer, Adam Brookfield, Floriana Tuna, Ashley J. Wooles, Michael Bodensteiner, Max M. Hansmann, Stephen T. Liddle

{"title":"A crystalline uranium Fischer-type carbyne","authors":"John A. Seed, Jhen-Kuei Yu, Florian Meurer, Adam Brookfield, Floriana Tuna, Ashley J. Wooles, Michael Bodensteiner, Max M. Hansmann, Stephen T. Liddle","doi":"10.1038/s41557-026-02260-0","DOIUrl":"https://doi.org/10.1038/s41557-026-02260-0","url":null,"abstract":"Since their discovery in 1973, transition metal Fischer carbynes have become a foundational class of metal–carbon triple bond in organometallic chemistry. However, even though the uranium Fischer carbyne bonding motif has been a fundamental target in f-element chemistry, its isolation has remained challenging. Here we report the synthesis and characterization of the uranium Fischer-type carbyne complex [N″3U(μ-CNN)UN″3] (N″ = N(SiMe3)2). Single-crystal X-ray diffraction analysis reveals a uranium–carbyne distance of 2.379(15) Å, and density functional theory calculations combined with experimental quantum crystallography Hirshfeld atom refinement reveal the presence of two-electron C→U σ-donation, weak two-electron C→U π-donations and two orthogonal one-electron U→C π-back-bonds, demonstrating σ2π1π1 Fischer-type carbyne bonding overall. This work redefines the range of bonding modes for the diazomethanediide ligand and reveals a uranium–carbon triple-bond interaction that is related, yet distinct from transition metal Fischer carbynes, providing a basis to develop and understand f-element carbyne chemistry.","PeriodicalId":18909,"journal":{"name":"Nature chemistry","volume":"24 1","pages":""},"PeriodicalIF":21.8,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149087898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The many lives of a universal solvent 万能溶剂的多寿命

IF 24.5 1区化学

Nature chemistry Pub Date : 2026-09-30 DOI: 10.1038/s41557-026-02254-y

Yasir S. Raouf

引用次数: 0

Bug bites 蚊虫叮咬

IF 24.5 1区化学

Nature chemistry Pub Date : 2026-09-30 DOI: 10.1038/s41557-026-02255-x

Michelle Francl

引用次数: 0

Linking vibrational energetics to carbon isotope separation in CO₂ electrolysis. 二氧化碳电解中振动能量学与碳同位素分离的联系。

IF 24.5 1区化学

Nature chemistry Pub Date : 2026-09-29 DOI: 10.1038/s41557-026-02262-y

引用次数: 0

Molecular engineering stabilizes the commensurate charge density wave state in 1T-TaS₂/arginine hybrid superlattices. 分子工程稳定了1T-TaS2/精氨酸杂化超晶格中的相应电荷密度波态。

IF 24.5 1区化学

Nature chemistry Pub Date : 2026-09-29 DOI: 10.1038/s41557-026-02241-3

Jingyuan Zhou, Boxuan Zhou, Chih-En Hsu, Katherine Pettersen, Jingxuan Zhou, Zhong Wan, Xingxu Yan, Huaying Ren, Qi Qian, Ao Zhang, Bosi Peng, Ranning Tang, Xiaoqing Pan, Zdenek Sofer, Hung-Chung Hsueh, Zhenglu Li, Yu Huang, Xiangfeng Duan

{"title":"Molecular engineering stabilizes the commensurate charge density wave state in 1T-TaS2/arginine hybrid superlattices.","authors":"Jingyuan Zhou, Boxuan Zhou, Chih-En Hsu, Katherine Pettersen, Jingxuan Zhou, Zhong Wan, Xingxu Yan, Huaying Ren, Qi Qian, Ao Zhang, Bosi Peng, Ranning Tang, Xiaoqing Pan, Zdenek Sofer, Hung-Chung Hsueh, Zhenglu Li, Yu Huang, Xiangfeng Duan","doi":"10.1038/s41557-026-02241-3","DOIUrl":"https://doi.org/10.1038/s41557-026-02241-3","url":null,"abstract":"The commensurate charge density wave (CCDW) phase in 1T-TaS2 is a prototypical correlated state tied to diverse emergent quantum phenomena. However, its stability is intrinsically limited to cryogenic temperatures. Tailoring correlated electronic states and stabilizing the CCDW phase at room temperature offer new opportunities to investigate and control emergent phenomena under ambient conditions. Here we report a molecular engineering strategy to modulate the charge density wave (CDW) phases in 1T-TaS2/arginine hybrid superlattices. We show that the intercalated arginine molecules exhibit strong non-covalent interactions with the 1T-TaS2 atomic layers, effectively modulating the correlated electronic phase and increasing the CCDW stabilization temperature to 330 K. In contrast, other weakly interacting amino acids produce a less pronounced modulation of the CDW phase transitions. Computational modelling reveals that arginine molecules reshape the CDW energy landscape, enhancing both the thermodynamic stability and kinetic robustness against thermal fluctuations. These findings establish a versatile molecular engineering strategy for tailoring correlated states and electronic orders in van der Waals materials.","PeriodicalId":18909,"journal":{"name":"Nature chemistry","volume":" ","pages":""},"PeriodicalIF":24.5,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep reduction in electrosynthesis 电合成中的深度还原。

IF 24.5 1区化学

Nature chemistry Pub Date : 2026-09-28 DOI: 10.1038/s41557-026-02249-9

Mickaël E. Avanthay, John R. Box, Alastair J. J. Lennox

{"title":"Deep reduction in electrosynthesis","authors":"Mickaël E. Avanthay, John R. Box, Alastair J. J. Lennox","doi":"10.1038/s41557-026-02249-9","DOIUrl":"10.1038/s41557-026-02249-9","url":null,"abstract":"Electrochemical reduction is solidifying its role as an increasingly important and practical alternative to the use of conventional stoichiometric chemical reductants. Not only can this technique be sustainable, safe and scalable, but it provides a facile approach to accessing deep reduction potentials (approximately <–2.5 V versus Fc+/Fc) that may be inaccessible using common reductants or accessible only using highly reactive and potentially unsafe reagents. Hence, over recent years substantial efforts have been made to develop electrochemical deep reduction to enable safer access to new areas of chemical space. While hazardous reagents have been replaced and novel transformations have been invented, the technique also comes with its challenges. In this review, we provide context to the issues that can arise when applying very reducing potentials and offer examples of mitigating strategies by describing selected transformations that are enabled or improved by deep electrochemical reduction. Deep electrochemical reduction offers a safe and sustainable route to reduction potentials beyond the reach of many conventional reagents. In this Review, the authors detail how these conditions can enable new reactivity and transformations, and strategies to mitigate the challenges of extreme reducing environments.","PeriodicalId":18909,"journal":{"name":"Nature chemistry","volume":"18 10","pages":"1694-1707"},"PeriodicalIF":24.5,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unmasking phenylalanine interactions through bioorthogonal decaging. 通过生物正交老化揭示苯丙氨酸相互作用。

IF 24.5 1区化学

Nature chemistry Pub Date : 2026-09-25 DOI: 10.1038/s41557-026-02277-5

引用次数: 0

Avoiding the path of LIESST resistance 避免了LIESST阻力的路径

IF 24.5 1区化学

Nature chemistry Pub Date : 2026-09-25 DOI: 10.1038/s41557-026-02259-7

Conor T. Kelly, Grace G. Morgan

引用次数: 0