Nanoscience and Nanotechnology Letters最新文献_第6页

The Researches and Applications of Reverse Engineering in the Protection and Inheritance of National Handcrafts 逆向工程在民族手工艺保护与传承中的研究与应用

Nanoscience and Nanotechnology Letters Pub Date : 2020-09-01 DOI: 10.1166/NNL.2020.3215

Dehai Zhang, Junheng Li, Huimin Zhu, Shujun Liu, K. Yu, Z. Guo, Liang Fu

{"title":"The Researches and Applications of Reverse Engineering in the Protection and Inheritance of National Handcrafts","authors":"Dehai Zhang, Junheng Li, Huimin Zhu, Shujun Liu, K. Yu, Z. Guo, Liang Fu","doi":"10.1166/NNL.2020.3215","DOIUrl":"https://doi.org/10.1166/NNL.2020.3215","url":null,"abstract":"National handcrafts are well-known at home and Abroad for their fine ingredients, exquisite blending of colors, and excellent skilled shaping and painting. What is more, they have great value and are deeply popular with people around the world. National handcrafts, as a cultural crystallization,\u0000 must be protected. In order to better realize the protection, we try to apply the technology of reverse engineering to the protection. This article mainly takes a handcraft, Yan Zi YU (meaning “swallow fish”), as an example to expound and demonstrate the process of reverse engineering\u0000 technology. During this process, by using scanning technology of reverse engineering, the collection and splicing of the point cloud data, the theoretical analysis of the NURBS surface in the reconstruction phase, and other practical operations in other stages, reverse engineering can be used\u0000 to regenerate 3D modal data of the swallow fish and to inspect and analyse the errors in it through Geomagic Quality to ensure that the new model meets the precision requirements. Therefore, the reverse engineering technology can be completely applied to the protection of national handcrafts\u0000 so that they can fully demonstrate their own value and function. If the precision of reverse engineering detection can reach nanometric level, a breakthrough will promote the protection of cultural relics.","PeriodicalId":18871,"journal":{"name":"Nanoscience and Nanotechnology Letters","volume":"12 1","pages":"1063-1069"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48258605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Optimization Design of Electrochemical Biosensors Based on Gold Nanomaterials 基于金纳米材料的电化学生物传感器优化设计

Nanoscience and Nanotechnology Letters Pub Date : 2020-09-01 DOI: 10.1166/NNL.2020.3219

Haitao Hao

引用次数: 0

Study on Chitosan-Based Nanocomposite Hydrogel in Soft Tissue Defect of Hand 壳聚糖基纳米复合水凝胶修复手部软组织缺损的研究

Nanoscience and Nanotechnology Letters Pub Date : 2020-09-01 DOI: 10.1166/NNL.2020.3217

Jian Zhang, Zhao-xia Gao, Yao Zhang, J. Tian

引用次数: 3

The Effect of Immune-Related Genes on Colonic Adenocarcinoma Prognosis 免疫相关基因对结肠癌预后的影响

Nanoscience and Nanotechnology Letters Pub Date : 2020-09-01 DOI: 10.1166/NNL.2020.3209

M. Hou, Jiakang Ma, Xiaoyan Lin, Jun Ma

引用次数: 0

Cognitive Diagnostic Assessment of Power Supply Magnetic Components Design Based on Bayesian Network 基于贝叶斯网络的电源磁性元件设计认知诊断评估

Nanoscience and Nanotechnology Letters Pub Date : 2020-08-01 DOI: 10.1166/NNL.2020.3202

Yi Kuang, Bin Duan, Mengping Lv, Junfeng Wu

{"title":"Cognitive Diagnostic Assessment of Power Supply Magnetic Components Design Based on Bayesian Network","authors":"Yi Kuang, Bin Duan, Mengping Lv, Junfeng Wu","doi":"10.1166/NNL.2020.3202","DOIUrl":"https://doi.org/10.1166/NNL.2020.3202","url":null,"abstract":"The power electronics engineering education is aimed at helping students in becoming qualified electronics engineers. However, the existing evaluation method cannot reflect the students’ performance in knowledge-structure and skillsets objectively and accurately. To address these\u0000 issues and improve the effectiveness of the current evaluation method in the field, we propose a Bayesian network model-based cognitive diagnostic assessment method and demonstrate it to evaluate students’ knowledge and skills condition with the switched-mode power supply (SMPS) magnetic\u0000 components design task. The paper starts with a brief introduction to the SMPS inductor design. It continues with the Bayesian network model-based inductor proficiency model, inductor evidence model, and the task model for power magnetics volume and weight in the aerospace SMPS. Then we identify\u0000 the parameters in the graded response model, relations among variables, and calculate the conditional probability between variables. Finally, we use Markov Chain Monte Carlo estimation method to get the posterior probability distribution of proficiency variables by OpenBUGS. The results show\u0000 that this cognitive diagnostic assessment system can effectively reflect the students’ study performances, scientifically advise their future study plans, and effectively achieve the education goals.","PeriodicalId":18871,"journal":{"name":"Nanoscience and Nanotechnology Letters","volume":"12 1","pages":"1044-1053"},"PeriodicalIF":0.0,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42627361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Curcumin Coated with Polymethyl Methacrylate Nanoparticles on Lung Cancer Cells 聚甲基丙烯酸甲酯纳米颗粒包被姜黄素对肺癌细胞的影响

Nanoscience and Nanotechnology Letters Pub Date : 2020-08-01 DOI: 10.1166/NNL.2020.3205

Ximiao Ma, F. Fu

{"title":"Effect of Curcumin Coated with Polymethyl Methacrylate Nanoparticles on Lung Cancer Cells","authors":"Ximiao Ma, F. Fu","doi":"10.1166/NNL.2020.3205","DOIUrl":"https://doi.org/10.1166/NNL.2020.3205","url":null,"abstract":"Lung cancer is a malignant tumor with an extremely high incidence and mortality rate in clinical practice and its pathogenesis remains unclear at present. Currently, the methods for treating this disease have relatively high limitations. However, with the gradual maturity and application\u0000 of nanotechnology, a number of studies have pointed out that polymethyl methacrylate nanoparticles (PMMA-NPs) encapsulated with curcumin (Cur) possibly becomes a new and effective scheme for treating lung cancer. First of all, Cur-PMMA-NPs were prepared. Their sizes were determined by characterization\u0000 techniques, and their effects on lung cancer cells A549 were detected by Cell proliferation experiment and flow cytometry. The expression of apoptosis-related proteins in the cells was detected by Western blotting. The results showed that polyacrylic acid (PAA)-Cur-PMMA-NPs had a particle\u0000 size of (215.00±6.00) nm. The drug loading rate and the encapsulation rate of nanospheres were remarkably higher than those of free Cur (P < 0.05). After the intervention of PAA-Cur-PMMA-NPs in the cells, the cell proliferation and the Bcl-2 expression reduced, while the apoptotic\u0000 rate and the expression of Bax, Caspase-3, and Caspase-9 increased (P < 0.05). Accordingly, Cur-PMMA-NPs can inhibit lung cancer cells from growth and induce their apoptosis, so they are expected to become an effective intervention measure to improve the therapeutic effect on lung\u0000 cancer in the future.","PeriodicalId":18871,"journal":{"name":"Nanoscience and Nanotechnology Letters","volume":"12 1","pages":"1015-1021"},"PeriodicalIF":0.0,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45576290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Some Results on Recurrent Fractal Interpolation Function 关于循环分形插值函数的一些结果

Nanoscience and Nanotechnology Letters Pub Date : 2020-08-01 DOI: 10.1166/NNL.2020.3198

Wadia Faid Hassan Al-shameri

引用次数: 0

Study on the Wear and Abrasion Effect of Metal Nano-Coating Plug Connectors Under Atmospheric Corrosion Conditions 大气腐蚀条件下金属纳米涂层插头接头磨损磨损效果研究

Nanoscience and Nanotechnology Letters Pub Date : 2020-08-01 DOI: 10.1166/NNL.2020.3203

Peng-zhu Wang, Liang Xu

{"title":"Study on the Wear and Abrasion Effect of Metal Nano-Coating Plug Connectors Under Atmospheric Corrosion Conditions","authors":"Peng-zhu Wang, Liang Xu","doi":"10.1166/NNL.2020.3203","DOIUrl":"https://doi.org/10.1166/NNL.2020.3203","url":null,"abstract":"The plug connector is the most widely used type of separable connector; however, the sliding friction that occurs during the plug-in process causes wear and wiping effects. Wear is a form of damage that occurs to the anti-corrosion coating during the sliding process, and wiping refers\u0000 to the cleaning effect of corrosion products during the sliding process. Both have negative and positive effects on electrical contact reliability in corrosive environments. Therefore, wear and wiping are key factors in studying the life and reliability of connectors in atmospheric corrosion\u0000 environments. Atmospheric corrosion is the main mechanism leading to connector contact failure. There have been many related studies on simple connector atmospheric corrosion, but research on the influence of wear and wipe on atmospheric corrosion and the influence of contact resistance degradation\u0000 is still not comprehensive. To study the influence of wear and wiping on contact reliability during the plug connector-mating process, this work evaluates the metal nano-coating connector plugging process as the object, and the contact resistance degradation model under atmospheric corrosion\u0000 as the basis, and the effect of wear and wiping on corrosion degradation as the research tool. Ultimately, the influence of wear and wiping on contact resistance is studied in detail. Finally, combined with the actual usage of the plug-in connector, the contact reliability of metal nano-coating\u0000 plug connectors under the action of abrasion and wiping is studied.","PeriodicalId":18871,"journal":{"name":"Nanoscience and Nanotechnology Letters","volume":"12 1","pages":"1006-1014"},"PeriodicalIF":0.0,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43221661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regulating Age-Related Hearing Loss with Bisphenol A via the Long Non-Coding RNA X Inactive Specific Transcript and MicroRNA-34a-5p Pathways 双酚A通过长非编码RNA X非活性特异性转录物和MicroRNA-34a-5p途径调节年龄相关性听力损失

Nanoscience and Nanotechnology Letters Pub Date : 2020-08-01 DOI: 10.1166/NNL.2020.3200

Shifei Wang, C. Rao, Xin-Qiong Huang, Tianhong Xie, Linling Su, Huan Li

{"title":"Regulating Age-Related Hearing Loss with Bisphenol A via the Long Non-Coding RNA X Inactive Specific Transcript and MicroRNA-34a-5p Pathways","authors":"Shifei Wang, C. Rao, Xin-Qiong Huang, Tianhong Xie, Linling Su, Huan Li","doi":"10.1166/NNL.2020.3200","DOIUrl":"https://doi.org/10.1166/NNL.2020.3200","url":null,"abstract":"Age-related hearing loss (AHL) is a common, high-incidence, perceptual disease in the elderly population worldwide. Since bisphenol A (BPA) has been reported to associate with cell apoptosis, we hypothesize that BPA can inhibit the neuronal apoptosis in AHL. Forty Wistar rats were recruited\u0000 to model AHL; they were then treated with different doses of BPA. We used auditory brainstem response testing to measure the BPA-induced improvement in the rats’ hearing. We examined the proliferation and apoptosis of the auditory cortical neurons in the rats with MTT assay and flow\u0000 cytometry. Also, to delineate the underlying mechanism of BPA’s effect on AHL, we quantitated the expression level of long non-coding RNA X inactive specific transcript (lncRNA XIST) and miR-34a-5p in the rats’ auditory cortex with a novel method called nanoparticle PCR. We found\u0000 that BPA intervention improved the hearing of AHL model rats, enhanced neuronal cell proliferation, restricted neuronal cell apoptosis, upregulated miR-34a-5p levels, and downregulated lncRNA XIST levels. The dual-luciferase reporter (DLR) assay revealed that BPA inhibited the apoptosis of\u0000 auditory cortex neurons by targeting miR-34a-5p with lncRNA XIST and regulated the process of AHL. Therefore, we come to a conclusion that BPA contributes to the improvement of AHL, which may be achieved by upregulating miR-34a-5p and inhibiting the apoptosis of auditory cortex neurons via\u0000 lncRNA XIST.","PeriodicalId":18871,"journal":{"name":"Nanoscience and Nanotechnology Letters","volume":"12 1","pages":"987-995"},"PeriodicalIF":0.0,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44684606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship Between cAMP Responsive Element Binding Protein and Its Phosphorylated Form in Cardiac Myxoma with DNA Mutation of Protein Kinase cAMP-Dependent Type I Regulatory Subunit Alpha 心脏黏液瘤中cAMP响应元件结合蛋白及其磷酸化形式与蛋白激酶cAMP依赖性I型调节亚基α DNA突变的关系

Nanoscience and Nanotechnology Letters Pub Date : 2020-08-01 DOI: 10.1166/NNL.2020.3199

Yang Sun, Qianlong Chen, Yujing Zhang, Wenke Li, Kun Zhao, Qingzhi Wang, Hongyue Wang, Zhou Zhou

{"title":"The Relationship Between cAMP Responsive Element Binding Protein and Its Phosphorylated Form in Cardiac Myxoma with DNA Mutation of Protein Kinase cAMP-Dependent Type I Regulatory Subunit Alpha","authors":"Yang Sun, Qianlong Chen, Yujing Zhang, Wenke Li, Kun Zhao, Qingzhi Wang, Hongyue Wang, Zhou Zhou","doi":"10.1166/NNL.2020.3199","DOIUrl":"https://doi.org/10.1166/NNL.2020.3199","url":null,"abstract":"Considering the lack of information regarding the role and mechanism of low expression of PRKAR1α in cardiac myxoma, we investigated the relationship between the low expression of PRKAR1α and the cAMP responsive element binding protein (CREB) and the\u0000 expression of its phosphorylated form (p-CREB) in cardiac myxoma tissue. For this purpose, we conducted a retrospective analysis of 130 cases of CM tissue obtained by surgical resection, from which paraffin-fixed tissue DNA was extracted, followed by detection of PRKAR1A DNA\u0000 mutation by Sanger sequencing and detection of CREB, p-CREB, and PKAR1α protein expression by immunohistochemical SP method. Mutations in the PRKAR1A gene coding region were detected in 35 (46.05%) of 76 sporadic CM tissues, of which 48.57% (17/35 cases) had more\u0000 than two mutations, and 28.57% (10/35 cases) had exon4: C.349-4-C.349-5insertTmutation. Compared with the surrounding normal tissues, 55.26% (42/76 cases) of PKAR1α protein was not expressed or weakly expressed, CREB was not expressed in myxoma and myocardial tissues, p-CREB\u0000 was expressed in 51 (67.11%) CM-positive tissues, and PKAR1α and p-CREB expression demonstrated no correlation (P > 0.05). These results indicate the presence of a high level of CREB phosphorylation in cardiac myxoma tissue; however, its phosphorylation\u0000 is not associated with mutations in the PRKAR1A gene coding region and PKAR1α expression.","PeriodicalId":18871,"journal":{"name":"Nanoscience and Nanotechnology Letters","volume":"12 1","pages":"979-986"},"PeriodicalIF":0.0,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64673216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0