Nanoscience and Nanotechnology Letters最新文献_第10页

Applications of Field Effect Transistor Biosensors Integrated in Microfluidic Chips 集成场效应晶体管生物传感器在微流控芯片中的应用

Nanoscience and Nanotechnology Letters Pub Date : 2020-04-01 DOI: 10.1166/nnl.2020.3138

Lemeng Chao, Shi Huanhuan, Kaixuan Nie, Bo Dong, Jiafeng Ding, Mengqiu Long, Zhengchun Liu

引用次数: 7

Fracture Mechanism on Supercritical Carbon Dioxide Blasting in Low-Permeability Coal Under Various Crustal Stresses 不同地壳应力下低渗透煤超临界二氧化碳爆破破裂机理

Nanoscience and Nanotechnology Letters Pub Date : 2020-04-01 DOI: 10.1166/nnl.2020.3156

Liwei Xin

引用次数: 2

Effect of Protection Articles of Nanomaterial Combined with Comfort Care on Mental Health of Patients with Corona Virus Disease 2019 纳米材料防护用品与舒适护理相结合对2019冠状病毒病患者心理健康的影响

Nanoscience and Nanotechnology Letters Pub Date : 2020-04-01 DOI: 10.1166/nnl.2020.3143

Yantao Liu, Lita Yuan, Shao-Dun Wen, Man Liang

{"title":"Effect of Protection Articles of Nanomaterial Combined with Comfort Care on Mental Health of Patients with Corona Virus Disease 2019","authors":"Yantao Liu, Lita Yuan, Shao-Dun Wen, Man Liang","doi":"10.1166/nnl.2020.3143","DOIUrl":"https://doi.org/10.1166/nnl.2020.3143","url":null,"abstract":"The outbreak of corona virus disease 2019 (COVID-19) challenges medical systems in our country, and it also causes distress for infected patients Care is required by patients with COVID-19 Quality care is important for protecting the physical and mental health of patients with COVID-19 Owing to the extremely infectious nature of COVID-19, patients are more sensitive when it concerns to protective articles Safe and comfortable protection materials are conducive to the promotion of the physical and mental recovery of patients Protection articles of nanomaterial (PAN), a new type of protection article, possesses bactericidal ability, and can help patients in resisting the invasion of external adverse substances Hence, it is of great significance to probe into the effect of PAN combined with comfort care on the mental health of patients diagnosed with COVID-19 Comparisons between patients who use PAN and patients who used general articles were conducted in terms of negative emotions, self-efficacy, mental elasticity, coping style, and care evaluation These comparisons revealed that PAN can greatly reduce patients' anxiety, depression, and negative emotions, and can also improve patients' self-efficacy and mental elasticity Patients using PAN and patients using general protection articles were compared in terms of comfortable living, satisfaction with protection, and self-psychological evaluation prior to care All patients' scores were improved following care, yet the scores of patients using PAN were significantly higher than those who used general protective articles Hence, this study suggests that comfort care can effectively improve the mental health of patients Comfort care along with the usage of PAN possesses better synergistic promotion ability","PeriodicalId":18871,"journal":{"name":"Nanoscience and Nanotechnology Letters","volume":"12 1","pages":"490-497"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41870014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Clinical Effects of Sensor AR40E Intraocular Lenses in Cataract Patients with Prominent Myopia 传感器AR40E人工晶状体在重度近视白内障患者中的临床应用

Nanoscience and Nanotechnology Letters Pub Date : 2020-04-01 DOI: 10.1166/nnl.2020.3141

Wenying Wang, Zhixue Wang, Yu Liu, Yuanyuan Zou, Xiangning Ji, Yong Liang, Ze-Bang Sun

{"title":"Clinical Effects of Sensor AR40E Intraocular Lenses in Cataract Patients with Prominent Myopia","authors":"Wenying Wang, Zhixue Wang, Yu Liu, Yuanyuan Zou, Xiangning Ji, Yong Liang, Ze-Bang Sun","doi":"10.1166/nnl.2020.3141","DOIUrl":"https://doi.org/10.1166/nnl.2020.3141","url":null,"abstract":"Cataracts are a complex group of eye disorders. Many studies suggest that blood circulation around the eyes, and a rise in intraocular pressure play important roles in glaucoma. Sensor AR40E artificial crystalline bodies can adjust intraocular pressure, improve activity in the optic\u0000 nerve and increase blood flow to the eye fundus. BL1 can transport Yin and Yang. We designed a randomized, military blind, controlled clinical trial: Control group: (1) A Sensor only AR40E intraocular lens was applied to the skin of Qingming and retrobulbar acupoints on the rainy side, twice\u0000 per week for 20 min every time, for two consecutive weeks; (2) acupuncture group: treatment was same as for the control group, but the eye was needled into Jingming and retrobulbar acupoints to achieve Qi; (3) Sensor AR40E intraocular lens group: treatment was the same as that for the acupuncture\u0000 group, the main outcome measure was the change of intraocular pressure and the secondary outcome measure is the score change of WHOQOL ref (Taiwan version). Beneficial outcomes were realized in the right and left eye acupuncture groups and the Sensor AR40E intraocular lens group.","PeriodicalId":18871,"journal":{"name":"Nanoscience and Nanotechnology Letters","volume":"12 1","pages":"461-466"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46431899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Significance of MicroRNA-155-Regulated Autophagy and Apoptosis by Targeting Rictor/Fos in Gastric Cancer Progression microrna -155靶向Rictor/Fos调控胃癌自噬和凋亡的临床意义

Nanoscience and Nanotechnology Letters Pub Date : 2020-04-01 DOI: 10.1166/nnl.2020.3144

Gang Chen, Yumin Li, Zhijian Ren, Yanmei Gu, Futian Tang, Jie Mao, Junmin Zhu, Ling Wang, Yumin Li

{"title":"Clinical Significance of MicroRNA-155-Regulated Autophagy and Apoptosis by Targeting Rictor/Fos in Gastric Cancer Progression","authors":"Gang Chen, Yumin Li, Zhijian Ren, Yanmei Gu, Futian Tang, Jie Mao, Junmin Zhu, Ling Wang, Yumin Li","doi":"10.1166/nnl.2020.3144","DOIUrl":"https://doi.org/10.1166/nnl.2020.3144","url":null,"abstract":"MicroRNA-155 plays an important role in the pathogenesis, progression, and treatment of various cancers. It is abnormally expressed in gastric cancer, but its expression level, function, and significance remain controversial. Therefore, we studied these facets of microRNA-155 in gastric cancer. A total of 700 (miRDB) and 556 (TargetScan) target genes were obtained and 280 genes were identified by Venn mapping, 49 of which had a target score of 90 or higher. GO and KEGG analysis revealed that they were associated with the autophagy and apoptosis pathways. Rictor and Fos were selected for further study. Thirty-two cases exhibited high microRNA-155 expression (group H) and 11 cases showed low expression (group L). Twelve patients had high Rictor expression, whereas 31 patients exhibited low expression. Thirteen cases showed normal Fos expression and 30 cases had low or negative expression. Thirty-three cases had high Beclin1/LC3 expression, whereas 10 cases exhibited low expression. Ten cases had high caspase-3 and caspase-9 expression, whereas 33 cases had low expression. According to the results of immunohistochemistry and western blot analyses, Rictor, Fos, caspase-3, and caspase-9 were minimally expressed, whereas Beclin1 and LC3 were highly expressed in group H. However, all six genes exhibited no significant expression differences in group L. The abnormal expression of microRNA-155 may indicate the occurrence of gastric cancer and its expression level was negatively correlated with the clinical stage of cancer. Down-regulated expression of Rictor and Fos, enhancement of autophagy, and reduced apoptosis may be related to the overexpression of microRNA-155. MicroRNA-155 may promote the progression of gastric cancer by promoting autophagy and inhibiting apoptosis.","PeriodicalId":18871,"journal":{"name":"Nanoscience and Nanotechnology Letters","volume":"12 4","pages":"525-535"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147887606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Ophiopogon Saponin B Affects the Proliferation, Apoptosis, and Oxidative Stress of Osteosarcoma Cells by Regulating POU Class 3 Homeobox 3 Expression 麦冬皂苷B通过调控POU Class 3 Homeobox 3表达影响骨肉瘤细胞增殖、凋亡和氧化应激

Nanoscience and Nanotechnology Letters Pub Date : 2020-04-01 DOI: 10.1166/nnl.2020.3136

Zhengmao Guan, Yi Wang, Weifan Xu, Jianfeng Wu

{"title":"Ophiopogon Saponin B Affects the Proliferation, Apoptosis, and Oxidative Stress of Osteosarcoma Cells by Regulating POU Class 3 Homeobox 3 Expression","authors":"Zhengmao Guan, Yi Wang, Weifan Xu, Jianfeng Wu","doi":"10.1166/nnl.2020.3136","DOIUrl":"https://doi.org/10.1166/nnl.2020.3136","url":null,"abstract":"Osteosarcoma is characterized by early lung metastasis and a high recurrence rate. Research on anti-osteosarcoma drugs is progressing slowly, and patient survival rates have not been improved. Ophiopogon saponin B (OP-B), a steroidal saponin monomer extracted from the ophiopogon japonicus,\u0000 is effective in the treatment of many cancers. We explored the mechanism underlying the in vitro effects of OP-B on proliferation, apoptosis, and oxidative stress in cultured osteosarcoma U2OS cells. We observed significant reductions in optical density, clonal number, and expression\u0000 of superoxide dismutase, glutathione peroxidase, and POU Class 3 Homeobox 3 (POU3F3) in the presence of OP-B. OP-B also increased the apoptotic rate and malondialdehyde expression. Downregulation of POU3F3 inhibited U2OS proliferation and oxidative stress in osteosarcoma cells and promoted\u0000 apoptosis. OP-B reduced POU3F3 expression in U2OS cells, and overexpression of POU3F3 reversed the effects of OP-B on proliferation, apoptosis, and oxidative stress. We thus conclude that OP-B promotes apoptosis and inhibits proliferation and the oxidative stress response of osteosarcoma cells\u0000 by downregulating POU3F3 expression. These results suggest an avenue for the research and development of new drugs for osteosarcoma.","PeriodicalId":18871,"journal":{"name":"Nanoscience and Nanotechnology Letters","volume":"12 1","pages":"518-524"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47052968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Aedes albopictus Monitoring Methods and Dengue Risk Assessment in Central China 中部地区白纹伊蚊监测方法与登革热风险评估比较

Nanoscience and Nanotechnology Letters Pub Date : 2020-04-01 DOI: 10.1166/nnl.2020.3133

Chuanwei Chen, Huaiqing Zhang, Qiyong Liu, Yu Li, Ji-Qi Liu, Liu Xiaobo, Song Xiuping, Zhili Jiang, Jie Li, Ning Zhao, Li Zhu, Yang Shen, Yujuan Yue, Zhen-Qiang Tang, Chaoqun Gao, Yuhong Guo

{"title":"Comparison of Aedes albopictus Monitoring Methods and Dengue Risk Assessment in Central China","authors":"Chuanwei Chen, Huaiqing Zhang, Qiyong Liu, Yu Li, Ji-Qi Liu, Liu Xiaobo, Song Xiuping, Zhili Jiang, Jie Li, Ning Zhao, Li Zhu, Yang Shen, Yujuan Yue, Zhen-Qiang Tang, Chaoqun Gao, Yuhong Guo","doi":"10.1166/nnl.2020.3133","DOIUrl":"https://doi.org/10.1166/nnl.2020.3133","url":null,"abstract":"Dengue fever has been attracting more attention in recent years. Dengue fever is mainly transmitted to humans by the Aedes albopictus mosquito and disease patterns are influenced by its wide distribution and high density during the summer season in China. Dengue epidemics in central\u0000 China previously occurred exclusively in rural areas, while these recent outbreaks mostly occurred in urban areas in southern China. Until now, the presence of Aedes Albopictus in central China has been scarcely acknowledged. This study is a survey of Aedes and attempts to clarify this new\u0000 distribution pattern using the Breteau Index (BI) method and a polylactic-glycolic acid (PLGA) copolymer mosquito trap simultaneously in urban and rural areas. The BI can provide a direct value on Aedes density compared to CI. Rural areas are at a higher risk for dengue compared to urban areas\u0000 in central China. Our findings provide a basis for the prevention and control of dengue vectors, as well as providing information for control strategies for other infectious diseases transmitted by Aedes mosquitoes. Vector control strategy related to the management of diseases transmitted\u0000 by Aedes should be based on the distribution patterns of different vector species, particularly in the rural environments in central China.","PeriodicalId":18871,"journal":{"name":"Nanoscience and Nanotechnology Letters","volume":"12 1","pages":"446-454"},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44865345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feature Detection of Nanofibers Based on Nonlinear Mapping Pattern Recognition 基于非线性映射模式识别的纳米纤维特征检测

Nanoscience and Nanotechnology Letters Pub Date : 2020-04-01 DOI: 10.1166/nnl.2020.3145

Minhong Sun, Jiang Duan

引用次数: 0

Clinical Significance of MicroRNA-155 Regulated Autophagy and Apoptosis by targeting gene Rictor/Fos in Gastric Cancer Progression MicroRNA-155靶向Rictor/Fos基因调控胃癌自噬和凋亡的临床意义

Nanoscience and Nanotechnology Letters Pub Date : 2020-03-25 DOI: 10.21203/rs.3.rs-18875/v1

Gang Chen, Yu Li, Zhijian Ren, Yan-Mei Gu, Fu-Tian Tang, J. Mao, Jun-min Zhu, Ling Wang, Yumin Li

引用次数: 6

Reduction of Breast Cancer Lymph Node Metastasis by Nano-Carbon Absorption of 5-Fluorouracil 纳米碳吸收5-氟尿嘧啶减少乳腺癌淋巴结转移

Nanoscience and Nanotechnology Letters Pub Date : 2020-03-01 DOI: 10.1166/nnl.2020.3110

Junheng Bai, Ting Guo, Wenwen Dong, Ying Song, Ting Guo, Mengsheng Cui

{"title":"Reduction of Breast Cancer Lymph Node Metastasis by Nano-Carbon Absorption of 5-Fluorouracil","authors":"Junheng Bai, Ting Guo, Wenwen Dong, Ying Song, Ting Guo, Mengsheng Cui","doi":"10.1166/nnl.2020.3110","DOIUrl":"https://doi.org/10.1166/nnl.2020.3110","url":null,"abstract":"To observe the clinical effect of nano-carbon adsorption of 5-fluorouracil (5-FU) on Breast cancer lymph node metastasis in New Zealand rabbits. A breast cancer animal model was established by local injection of a VX2 tumor tissue suspension in thirty New Zealand rabbits. An observation\u0000 group, control group A, and control group B were established using a random number table, with ten rabbits in each group. Once tumors with a diameter ≥5 mm were identified in the lymph nodes, the animals received the intervention. The observation group had nano-carbon-5-FU suspension subcutaneously\u0000 injected, control group A had 5-FU subcutaneously injected through the ear margin, and control group B had 5-FU subcutaneously injected; all received a drug dose of 30 mg · kg–1. Half of the animals in the three groups were killed following treatment for thirty minutes,\u0000 while the rest of the animals were killed following treatment for seven days. Tumors and lymphatic metastases were removed. Tumor and lymphatic metastasis volume were compared. H&E stained sections were used to determine the ND of tumor cells. A dTUP TUNEL assay using Terminal Deoxynucleotidyl\u0000 Transferase (TdT) was used to assess tumor cell apoptosis. The expression level of casapase-3 mRNA in tumors and lymphoid tissues was determined using RT-PCR. After treatment for 30 mins, the observation group exhibited a significantly higher 5-FU concentration in lymph node metastases, and\u0000 significantly lower 5-FU concentrations in plasma and tumors. Nano-carbon can increase the 5-FU concentration in tumor tissue, as well as enhance the clinical effect of drugs on lymph node metastases.","PeriodicalId":18871,"journal":{"name":"Nanoscience and Nanotechnology Letters","volume":"12 1","pages":"407-412"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48086419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2