Journal of Child Psychology and Psychiatry最新文献

{"title":"Reward-network connectivity in childhood predicts multi-domain dysregulation in adolescence.","authors":"Eugenia Giampetruzzi,Parmis Khosravi,Katharina Kircanski,Chase Antonacci,Daniel S Pine,Ian H Gotlib","doi":"10.1111/jcpp.70143","DOIUrl":"https://doi.org/10.1111/jcpp.70143","url":null,"abstract":"BACKGROUNDMulti-domain dysregulation in adolescence, indexed by co-occurring affective, cognitive, and behavioural difficulties, is a robust transdiagnostic risk factor. However, its developmental course and neural antecedents are poorly understood. Given heightened emotional reactivity and impulsivity in adolescence, alterations in reward-network connectivity may represent an early neural marker of risk.METHODSAdolescents completed four assessments approximately two years apart between ages 9-13 and 15-18 years. Multi-domain dysregulation was assessed at each wave using the Youth Self-Report Dysregulation Profile (YSR-DP), computed as the sum of the anxious/depressed, aggressive behaviour, and attention problems subscales. Resting-state fMRI was acquired at baseline (Mage = 11.34 years). Piecewise linear mixed-effects models (N = 211) characterized trajectories of YSR-DP scores across adolescence. Principal component scores indexing a Latent Dysregulation Factor were used to derive residualised change in dysregulation, and regression analyses (N = 94) tested whether baseline reward-network connectivity predicted this change.RESULTSYSR-DP scores declined from late childhood to early adolescence, increased from early to mid-adolescence, and then stabilized in late adolescence. Weaker connectivity within the reward network in late childhood predicted greater increases in the latent dysregulation factor from early to mid-adolescence, above and beyond baseline dysregulation. Connectivity in seven large-scale control networks did not predict changes in dysregulation.CONCLUSIONSMulti-domain dysregulation follows a nonlinear trajectory across adolescence, and weaker reward-network connectivity in childhood prospectively predicts subsequent escalation of this phenotype. Prevention and intervention efforts may benefit from targeting reward processing and regulatory skills in late childhood and early adolescence.","PeriodicalId":187,"journal":{"name":"Journal of Child Psychology and Psychiatry","volume":"99 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147329557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time-dependent association between prenatal hair glucocorticoid levels and child behavior problems.","authors":"Richard G Künzel, Yinxian Chen, Marta B Rondon, Diana Juvinao-Quintero, Laramie E Duncan, Sixto E Sanchez, Luz G Nateros, Archana Basu, Amantia Ametaj, Clemens Kirschbaum, Elizabeth J Levey, Bizu Gelaye","doi":"10.1111/jcpp.70131","DOIUrl":"10.1111/jcpp.70131","url":null,"abstract":"<p><strong>Background: </strong>Child internalizing and externalizing behavioral problems are highly prevalent psychiatric symptoms worldwide, for which maternal prenatal stress is a known risk factor. However, underlying neuroendocrine mechanisms remain largely unclear. We investigated whether maternal hair cortisol (HCC) and cortisone concentration (HCNC) are associated with offspring's internalizing and externalizing behavior problems in a prospective pre-birth cohort study from Perú.</p><p><strong>Methods: </strong>N = 271 mother-child dyads were included in this analysis. Recruitment and data collection took place at the Instituto Nacional Materno Perinatal in Lima, Perú. HCC and HCHC were obtained from hair segments representing up to 3 months pre-pregnancy and first trimester, respectively, and were quantified via liquid chromatography tandem mass spectrometry. The Child Behavior Checklist was used to assess internalizing and externalizing behavioral problems of children (mean age at follow-up = 6.98 years (SD = 1.05)). Marginal structural models estimated population average associations between HCC, HCNC, and internalizing and externalizing problems, adjusting for established covariates.</p><p><strong>Results: </strong>At pre-pregnancy, logHCNC was positively associated with offspring internalizing (β = 2.21, 95% CI: 0.46; 3.96, p = .013) and externalizing problems (β = 1.87, 95% CI: 0.34; 3.40, p = .016). At the first trimester, logHCNC was negatively associated with internalizing (β = -2.51, 95%CI: -4.37; -0.64, p = .008), and externalizing problems (β = -2.73, 95% CI: -4.18; -1.28, p < .001). Associations were stronger for females and not apparent for logHCC.</p><p><strong>Conclusions: </strong>We found time-dependent associations between stress-related prenatal hair glucocorticoid concentration and offspring behavioral problems. Modeling biomarker data time-dependently may prove critical to identifying the underlying mechanisms of transgenerational stress transmission.</p>","PeriodicalId":187,"journal":{"name":"Journal of Child Psychology and Psychiatry","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147281604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parent-led CBT delivered via online and telephone support alongside usual school practice versus usual school practice only for young children identified as at risk for anxiety disorders through screening in schools: a cluster randomised controlled trial.","authors":"Tessa Reardon, Obioha C Ukoumunne, Helen Dodd, Gemma Halliday, Claire Hill, Bec Jasper, Benjamin Jones, Peter J Lawrence, Fran Morgan, Anna Placzek, Ronald M Rapee, Mara Violato, Shuye Yu, Cathy Creswell","doi":"10.1111/jcpp.70119","DOIUrl":"https://doi.org/10.1111/jcpp.70119","url":null,"abstract":"<p><strong>Background: </strong>Providing accessible CBT for young children identified as at risk for anxiety disorders through screening in schools could reduce later problems. This study aimed to evaluate the effectiveness of parent-led CBT delivered via online and telephone call support alongside usual school provision, compared to usual school provision only for young children identified through screening as having at least one risk.</p><p><strong>Methods: </strong>We conducted a pragmatic, parallel group, superiority cluster randomised controlled trial in 95 primary/infant schools in England. Parents of children (aged 4-7) in sampled classes completed screening, and children who screened positive for one or more risks (anxiety symptoms/inhibition/parent anxiety) were eligible for the trial. Schools (clusters) were randomised (1:1) to intervention or usual school practice, stratified by school-level deprivation. Schools in both arms continued with usual provision, and parents in intervention schools were offered parent-led CBT via online and telephone support. The primary outcome was the presence of an anxiety disorder diagnosis at 12 months, assessed via the ADIS-P administered by independent assessors. Secondary clinical outcomes included parent-reported child anxiety symptoms, related interference, externalising symptoms, additional risks and intervention targets at 12 weeks and 12 months. Primary analyses were conducted on the full intention-to-treat population. The trial was prospectively registered with ISRCTN 82398107.</p><p><strong>Results: </strong>In total, 2,328 children were screened; 1,172 were eligible; 865 enrolled. Forty-eight schools (434 children) were assigned to intervention and 47 schools (431 children) to usual school practice. At 12 months, the overall frequency of anxiety disorders was low, 6.8% (21/310) of children in the intervention arm compared to 11.5% (36/312) in the usual school practice arm; this difference was not statistically significant (adjusted odds ratio 0.67 [0.37 to 1.21], p = .19). However, the intervention was superior to usual school practice across all secondary outcomes (standardised mean difference: 0.15 to 0.47 at 12 weeks; 0.19 to 0.41 at 12 months). No serious adverse events were reported.</p><p><strong>Conclusions: </strong>Although the intervention did not significantly reduce anxiety disorders at 12 months, improvements across all other assessed outcomes indicate this approach brings wider immediate benefits and reduces known risks for future anxiety disorders. Future research needs to consider longer-term preventative effects.</p>","PeriodicalId":187,"journal":{"name":"Journal of Child Psychology and Psychiatry","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146224904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indirect genetic effects of siblings","authors":"Mathias Valstad, Espen Moen Eilertsen, Ziada Ayorech, Rosa Cheesman, Perline Demange, Nikolai Haahjem Eftedal, Alexandra Havdahl, Eivind Ystrom","doi":"10.1111/jcpp.70130","DOIUrl":"https://doi.org/10.1111/jcpp.70130","url":null,"abstract":"Background Within‐family designs are increasingly used to decompose genotype–trait associations into direct and indirect genetic effects. Many such designs, including trio designs or within‐sibship designs, assume an absence of sibling indirect genetic effects. Methods We expand two well‐known molecular genetic within‐family designs, one variance component (genome‐based restricted maximum likelihood) and one trait‐based (structural equation modeling with polygenic indices), to estimate sibling indirect genetic effects, along with direct genetic effects. We link the Norwegian Mother, Father, and Child Cohort Study (MoBa) to Norway's national education database to model genetic effects on national standardized testing results at ages 10, 13, and 14, and on parent‐rated attention‐deficit hyperactivity disorder (ADHD) symptoms at ages 3 and 8 in up to 15,971 genotyped and phenotyped siblings. Results Estimates of direct and indirect genetic effects from the genome‐based restricted maximum likelihood and the structural equation modeling with polygenic indices approaches converge, albeit with the variance component estimates typically an order of magnitude greater than the trait‐based estimates. We observe no indirect genetic effects of siblings on educational performance at any age, and only slightly negative indirect genetic effects of siblings on ADHD symptoms at age 3. We argue that the latter effect might reflect parental contrasting ratings. Conclusions The results suggest that within‐family models of educational performance are unlikely to be drastically biased by an assumption of absent sibling indirect genetic effects. Combining trait‐based analyses with variance component analyses can benefit understanding of indirect genetic effects, especially when the effects are not specific to a particular mechanism.","PeriodicalId":187,"journal":{"name":"Journal of Child Psychology and Psychiatry","volume":"101 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146169425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal associations between violence exposure and adolescent conduct problems in a high‐adversity, South African setting","authors":"Susan Swingler, Qing Han, Alexis E. Cullen, Stefani du Toit, Sarah Skeen, Jane Barlow, Mark Tomlinson","doi":"10.1111/jcpp.70132","DOIUrl":"https://doi.org/10.1111/jcpp.70132","url":null,"abstract":"Background Violence exposure is a well‐established risk factor for adolescent conduct problems, yet longitudinal research in high‐adversity, low‐ and middle‐income countries (LMICs) remains limited. This study investigated whether early adolescent violence exposure predicts concurrent and longer‐term conduct problems, and explored potential bidirectional associations and sex differences in a peri‐urban South African community with high rates of poverty and violence. Methods Data were drawn from the Thula Sana birth cohort ( <jats:italic>n</jats:italic> = 357; 51.5% female), a longitudinal intervention study in Khayelitsha, South Africa. Adolescents were assessed at early (ages 12–14) and late adolescence (ages 16–19). Violence exposure was measured using adolescent self‐report. Conduct problems were measured using adolescent and caregiver report in early adolescence and adolescent self‐report in late adolescence. Multiple linear regressions tested cross‐sectional associations, and cross‐lagged panel models examined longitudinal and bidirectional associations, adjusting for contextual adversity and intervention status. Missing data were addressed using multiple imputation, and findings were confirmed through sensitivity analyses. Results Violence exposure was associated with higher concurrent conduct problems in early adolescence (β = .15–.19, <jats:italic>p</jats:italic> &lt; .01) and predicted higher conduct problems in late adolescence (β = .12–.14, <jats:italic>p</jats:italic> &lt; .05). The reverse pathway, from conduct problems to subsequent violence exposure, was not significant (β = .08–.11, <jats:italic>p</jats:italic> &gt; .05). Interaction analyses did not provide evidence that associations differed by sex. Conclusions Violence exposure in early adolescence represents a prospective risk factor for conduct problems in a high‐adversity South African setting. Findings highlight the importance of early, contextually grounded violence prevention and the need for further research to test sex‐specific pathways and inform the development of gender‐responsive intervention strategies.","PeriodicalId":187,"journal":{"name":"Journal of Child Psychology and Psychiatry","volume":"96 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146153677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The randomized controlled trial Fast Track multilevel intervention for children with early-emerging conduct problems breaks intergenerational transmission of violence across three generations.","authors":"Laura Gorla, W Andrew Rothenberg, Jennifer Godwin","doi":"10.1111/jcpp.70133","DOIUrl":"10.1111/jcpp.70133","url":null,"abstract":"<p><strong>Background: </strong>Domestic violence mechanisms are frequently transmitted across generations, representing a global issue demanding particular attention. This study investigates the intergenerational transmission of intimate partner violence (IPV) and parent-to-child violence (PCV) and whether participating in a multilevel preventive intervention (Fast Track) breaks this transmission.</p><p><strong>Methods: </strong>In high-risk elementary schools located in the United States, children considered at high risk for aggressive behavior based on teachers' and parents' screen scores were assigned to either a 10-year intervention or a control group based on their school. The Fast Track trial was registered at clinicaltrials.gov (NCT01653535) and was focused on parenting practices and children's intrapersonal, interpersonal, and academic skills. From the original 891 children, 374 participants with children aged less than 18 years (n = 191 intervention group, n = 183 control group) reported at age 34 their experience with domestic violence and their children's psychological adjustment.</p><p><strong>Results: </strong>The intergenerational mediating pathway from high IPV in the first generation to high PCV in the second generation to greater total mental health difficulties in the third generation was statistically significant in the control group but not in the intervention group.</p><p><strong>Conclusions: </strong>IPV was intergenerationally transmitted by influencing PCV, with a negative effect on the third generation's mental health. Nevertheless, participation in the Fast Track intervention disrupted this cycle. These findings suggest the importance of policies to support preventive childhood interventions.</p>","PeriodicalId":187,"journal":{"name":"Journal of Child Psychology and Psychiatry","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146155401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of parent-child interaction therapy dosage on child and parent outcomes: differentiating child-directed interaction and parent-directed interaction session impacts in child welfare-involved families.","authors":"Xiaolan Liao, Julia P Ruggiero, David E Bard, Adon F G Rosen, Elizabeth A Skowron","doi":"10.1111/jcpp.70106","DOIUrl":"10.1111/jcpp.70106","url":null,"abstract":"<p><strong>Background: </strong>Parent-child interaction therapy (PCIT) improves parenting and child behavior, yet little is known about how dosage of its two phases, warm relationship building focused child-directed interaction (CDI) sessions and safe, effective discipline skills-focused parent-directed interaction (PDI) sessions, contributes to outcomes, particularly in child welfare-involved families. Understanding these dose-response patterns can clarify the pathways through which PCIT produces change.</p><p><strong>Methods: </strong>In a sample of 204 child welfare families with young children, we examined the dose-response relationship between each PCIT phase and key intervention outcomes of positive and negative parenting skills and disruptive child behavior problems. We also used sequential mediation models to test time-ordered intervention dosage effects (i.e., number of CDI sessions completed and subsequent number of PDI sessions completed) on the parent and child outcomes.</p><p><strong>Results: </strong>Sequential mediation models showed that the PCIT intervention exerted significant indirect effects on increased positive parenting skills and decreased negative parenting behaviors and child behavior problems through higher dosage of relationship-enhancing CDI sessions followed by higher dosage of safe discipline-focused PDI sessions. Further, CDI dosage interacted with PDI dosage to predict greater gains in positive parenting skills outcomes.</p><p><strong>Conclusions: </strong>These results contribute new insights into the pathways through which PCIT shapes outcomes in a sample of child welfare-involved families. Findings also highlight the significant unique contribution that limit-setting-oriented PDI, a relatively understudied phase of PCIT, plays in enhancing positive parenting skills and mitigating child behavior problems.</p>","PeriodicalId":187,"journal":{"name":"Journal of Child Psychology and Psychiatry","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146111660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psycho-social factors associated with disagreement between prospective and retrospective measures of childhood maltreatment.","authors":"Oonagh Coleman,Jessie R Baldwin,Louise Arseneault,Helen L Fisher,Terrie E Moffitt,Andrea Danese","doi":"10.1111/jcpp.70129","DOIUrl":"https://doi.org/10.1111/jcpp.70129","url":null,"abstract":"BACKGROUNDProspective and retrospective measures of childhood maltreatment often identify different individuals and are differentially associated with psychopathology. This study examines psycho-social factors that may explain discrepancies between these measures.METHODSData were drawn from the Environmental Risk Longitudinal Twin Study, a nationally representative birth cohort of 2,232 children born in 1994-1995 across England and Wales and followed to age 18 (93% retention). Childhood maltreatment was assessed through: (a) prospective assessments from caregivers, researchers, and clinicians at ages 5-12, and (b) retrospective self-reports at age 18 using the Childhood Trauma Questionnaire (for maltreatment occurring up to age 12). For the analyses, we focused on participants identified as maltreated from either measure (n = 290) and an a-priori selected array of potential explanatory variables assessed between ages 5-18. We conducted two sets of analyses: comparing individuals with only prospectively identified maltreatment to those identified by both prospective and retrospective measures to understand why some participants did not retrospectively report or recall maltreatment; and comparing individuals with only retrospective self-reports to those identified by both prospective and retrospective measures to understand why maltreatment had not been detected prospectively.RESULTSParticipants in the prospective-only group reported greater social support over the life course and lower psychopathology at age 18 compared to those identified through both prospective and retrospective measures. Individuals in the retrospective-only group had higher socioeconomic status, higher self-reported adult involvement at age 12, and less exposure to domestic violence compared to those identified through both prospective and retrospective measures.CONCLUSIONSOur findings suggest that perceptions of social support and better mental health may buffer retrospective recall of childhood maltreatment in those with prospective measures. Furthermore, more positive family functioning and socioeconomic factors may hamper prospective detection of childhood maltreatment in those who retrospectively report it.","PeriodicalId":187,"journal":{"name":"Journal of Child Psychology and Psychiatry","volume":"82 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146089143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resource profiles and suicide attempts in youth with disabilities.","authors":"Minhae Cho,C Hyung Keun Park,Misa Kayama,Sujin Seo,Jungjoon Ihm","doi":"10.1111/jcpp.70122","DOIUrl":"https://doi.org/10.1111/jcpp.70122","url":null,"abstract":"BACKGROUNDThe issue of suicide among youth with disabilities transitioning into adulthood is a serious public health issue. In navigating this transition, youth with disabilities encounter unique obstacles that require careful consideration and support. This study aims to identify resource profiles among youth with disabilities and their association with suicide attempts in early adulthood.METHODSUsing data from the National Longitudinal Study of Adolescent Health (Add Health), this study included 1,472 youth with disabilities. A Gaussian finite mixture model (GMM) was employed to identify underlying distinct groups of youth with disabilities based on their available resources.RESULTSFour latent classes emerged: (1) Socioeconomically Advantaged and Socially Supportive (37%); (2) Socioeconomically Advantaged, but Socially Isolated (28%); (3) Socioeconomically Disadvantaged and Socially Isolated (20%); and (4) Socioeconomically Disadvantaged, but Socially Supportive (15%). Results from the generalized linear mixed model (GLMM) considering a longer transition period into adulthood up to age 32 and relevant time-varying factors found that youth in Socioeconomically Advantaged, but Socially Isolated and Socioeconomically Disadvantaged, but Socially Supportive had a significantly lower likelihood of suicide attempts compared to those in Socioeconomically Advantaged and Socially Supportive. The likelihood of suicide attempts for youth with learning disabilities was significantly lower than for those with physical disabilities, while a history of suicide attempts in adolescence and experience with a death by suicide of family members or friends increased the odds of suicide attempts.CONCLUSIONSThe study highlights the heterogeneity of youth with disabilities, demonstrating how demographic characteristics, disability-specific needs, family and school environments and social support systems intersect to influence suicide attempt prevention.","PeriodicalId":187,"journal":{"name":"Journal of Child Psychology and Psychiatry","volume":"30 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146073062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyzing transdiagnostic internalizing symptoms in a global sample of trauma‐exposed children using pooled individual participant data: a latent transition analysis","authors":"Yaara Sadeh, Leila Graham, Marthe R. Egberts, Lonneke I.M. Lenferink, Nancy Kassam‐Adams","doi":"10.1111/jcpp.70113","DOIUrl":"https://doi.org/10.1111/jcpp.70113","url":null,"abstract":"Background Children often experience both posttraumatic stress (PTS) and depression after potentially traumatic events (PTEs). Latent class analyses (LCAs) identify subgroups with different co‐occurring symptoms, but little is known about what predicts transitions between these symptom classes over time. Analyzing these transitions could reveal factors that influence the shift to classes with fewer internalizing symptoms. Methods Using harmonized individual participant data ( <jats:italic>n</jats:italic> = 787) from nine studies (United States, United Kingdom, Australia, and Switzerland) included in the Prospective studies of Acute Child Trauma and Recovery Data Archive (PACT/R), internalizing symptom classes (using PTS and depression items) were identified using LCAs for T1 (0–2 months posttrauma) and T2 (3–15 months posttrauma) separately. Latent transition analysis was used to examine predictors of transitions across symptom classes over time. Included predictors were age, gender, minority status, and trauma type. Results Five classes were identified at both time points: ‘low internalizing’ class (T1: 20%; T2: 40%), ‘low PTS/moderate‐high depression’ class (T1: 20%; T2: 27%), ‘moderate internalizing’ class (T1: 25%; T2: 12%), ‘moderate PTS/high depression’ class (T1: 17%, T2: 14%), and ‘high internalizing’ class (T1: 16%, T2: 6%). ‘Low internalizing’ was the most common and stable response (87% stayed in this class). At both time points, 40% of all children were classified into either a ‘low PTS/moderate‐high depression’ class or a ‘moderate PTS/high depression’ class. Children belonging to minority groups in their country of residence and children exposed to interpersonal PTEs were less likely to transition from the ‘high internalizing’ class to lower symptom classes. Conclusions Most children show low PTS and depression symptoms after PTEs. When symptoms do develop, they usually involve both high depression and PTS, rather than high PTS with low depression. This underscores the importance of assessing both conditions and developing interventions that target multiple disorders. Minority children exposed to interpersonal trauma require special focus in research and treatment.","PeriodicalId":187,"journal":{"name":"Journal of Child Psychology and Psychiatry","volume":"180 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146071502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}