Natural Polysaccharides in Drug Delivery and Biomedical Applications最新文献_第9页

Arrowroot and Cassava Mixed Starch Products Identification by Raman Analysis with Chemometrics 用化学计量学拉曼分析鉴别竹芋混合淀粉制品

Natural Polysaccharides in Drug Delivery and Biomedical Applications Pub Date : 2021-09-18 DOI: 10.3390/polysaccharides2030043

I. Macêdo, M. Cereda, C. D. Bet, J. F. S. S. Junior, M. Carvalho, E. Gil

{"title":"Arrowroot and Cassava Mixed Starch Products Identification by Raman Analysis with Chemometrics","authors":"I. Macêdo, M. Cereda, C. D. Bet, J. F. S. S. Junior, M. Carvalho, E. Gil","doi":"10.3390/polysaccharides2030043","DOIUrl":"https://doi.org/10.3390/polysaccharides2030043","url":null,"abstract":"Food frauds present a major problem in the foodstuff industry. Arrowroot and cassava may be targeted in adulteration and falsification processes. Raman analysis combined with chemometric techniques was proposed to identify the mixing and adulteration of these foodstuffs in commercial products. 67 cassava and 5 arrowroot samples were prepared in laboratory. 21 cassava and 5 arrowroot commercial samples were purchased in local stores. Raman assays were performed in the range of 400 to 2300 cm−1. Principal component analysis with K-means clustering was used to identify the adulteration of these products. It was possible to observe the separation of three different groups in the data, these groups labelled group 1, 2 and 3 were correspondent to cassava-like samples, mixed samples, and arrowroot-like samples, respectively. Despite the visual analysis related to sensory characteristics and the visual analysis of each Raman spectrum of cassava and arrowroot not being able to differentiate these foodstuffs, the chemometric approaches with the Raman specters data were able to identify which samples were pure arrowroot, pure cassava and which were mixed products. The proposed approach showed to be an effective tool in the investigation of fraud for arrowroot and cassava.","PeriodicalId":18775,"journal":{"name":"Natural Polysaccharides in Drug Delivery and Biomedical Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73801675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Polysaccharide Vaccines: A Perspective on Non-Typhoidal Salmonella 多糖疫苗:从非伤寒沙门氏菌的角度研究

Natural Polysaccharides in Drug Delivery and Biomedical Applications Pub Date : 2021-09-11 DOI: 10.3390/polysaccharides2030042

Sumudu R. Perera, A. Sokaribo, A. White

{"title":"Polysaccharide Vaccines: A Perspective on Non-Typhoidal Salmonella","authors":"Sumudu R. Perera, A. Sokaribo, A. White","doi":"10.3390/polysaccharides2030042","DOIUrl":"https://doi.org/10.3390/polysaccharides2030042","url":null,"abstract":"Polysaccharides are often the most abundant antigens found on the extracellular surfaces of bacterial cells. These polysaccharides play key roles in interactions with the outside world, and for many bacterial pathogens, they represent what is presented to the human immune system. As a result, many vaccines have been or currently are being developed against carbohydrate antigens. In this review, we explore the diversity of capsular polysaccharides (CPS) in Salmonella and other selected bacterial species and explain the classification and function of CPS as vaccine antigens. Despite many vaccines being developed using carbohydrate antigens, the low immunogenicity and the diversity of infecting strains and serovars present an antigen formulation challenge to manufacturers. Vaccines tend to focus on common serovars or have changing formulations over time, reflecting the trends in human infection, which can be costly and time-consuming. We summarize the approaches to generate carbohydrate-based vaccines for Salmonella, describe vaccines that are in development and emphasize the need for an effective vaccine against non-typhoidal Salmonella strains.","PeriodicalId":18775,"journal":{"name":"Natural Polysaccharides in Drug Delivery and Biomedical Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87469694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Composite Films of Thermoplastic Starch and CaCl2 Extracted from Eggshells for Extending Food Shelf-Life 从蛋壳中提取热塑性淀粉和CaCl2复合膜以延长食品保质期

Natural Polysaccharides in Drug Delivery and Biomedical Applications Pub Date : 2021-09-03 DOI: 10.3390/polysaccharides2030041

Jeovan A. Araujo, Y. J. Cortese, Marija Mojicevic, Margaret Brennan Fournet, Yuanyuan Chen

{"title":"Composite Films of Thermoplastic Starch and CaCl2 Extracted from Eggshells for Extending Food Shelf-Life","authors":"Jeovan A. Araujo, Y. J. Cortese, Marija Mojicevic, Margaret Brennan Fournet, Yuanyuan Chen","doi":"10.3390/polysaccharides2030041","DOIUrl":"https://doi.org/10.3390/polysaccharides2030041","url":null,"abstract":"Calcium chloride (CaCl2) has been widely used to maintain the quality of fresh-cut fruits and vegetables because it stabilizes and strengthens the membrane system against fungal attacks. It is mainly applied via spray coating and dip coating techniques. This study explored a method of incorporating calcium chloride extracted from eggshells in a packaging material, thermoplastic starch (TPS), via a hot-melt extrusion process. The composites were characterized by FTIR, DSC, SEM-EDX and tensile testing. FTIR confirmed the chemical reactions between CaCl2 and TPS. DSC results showed a significant decrease in the heat of fusion by adding 20 wt% of CaCl2 content in TPS, indicating a drop in the degree of crystallinity. The Young’s modulus of TPS was not significantly affected by the incorporation of 10 wt% CaCl2 (P = 0.968), but reduced notably with the addition of 20 wt% CaCl2 (P = 0.05), indicating the plasticizer effect of the CaCl2. Physiochemical analysis of fresh-cut apple slices was assessed. Samples placed on the surface of the TPS/CaCl2 composites displayed less pH reduction, reduced antioxidant activity, more weight loss and increased reducing sugar compared to the samples placed on the surface of virgin TPS films. CaCl2 released from the TPS/CaCl2 films was measured and their antimicrobial activity was confirmed by bacterial inhibitory growth assessment. Fungal growth was observed on apple slices placed on virgin TPS film by day 21 while apple slices placed on TPS/CaCl2 20 wt% composites did not support any fungal growth for 28 days. In summary, TPS and eggshell-extracted CaCl2 showed the ability to maintain the quality of fresh-cut apples, and TPS/CaCl2 10 wt% composite could be a good option as a packaging material for fresh-cut fruits due to active antimicrobial activity and maintained Young’s modulus.","PeriodicalId":18775,"journal":{"name":"Natural Polysaccharides in Drug Delivery and Biomedical Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75325725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Cinnamon Essential Oil Nanocellulose-Based Pickering Emulsions: Processing Parameters Effect on Their Formation, Stabilization, and Antimicrobial Activity 肉桂精油纳米纤维素酸洗乳剂:工艺参数对其形成、稳定性和抗菌活性的影响

Natural Polysaccharides in Drug Delivery and Biomedical Applications Pub Date : 2021-09-01 DOI: 10.3390/polysaccharides2030037

A. G. Souza, Rafaela Reis Ferreira, Elisa Silva Freire Aguilar, Leonardo Zanata, D. Rosa

{"title":"Cinnamon Essential Oil Nanocellulose-Based Pickering Emulsions: Processing Parameters Effect on Their Formation, Stabilization, and Antimicrobial Activity","authors":"A. G. Souza, Rafaela Reis Ferreira, Elisa Silva Freire Aguilar, Leonardo Zanata, D. Rosa","doi":"10.3390/polysaccharides2030037","DOIUrl":"https://doi.org/10.3390/polysaccharides2030037","url":null,"abstract":"This work aimed to prepare nanocellulose-based Pickering emulsions using cinnamon essential oil. Different formulations were investigated by varying the preparation time, homogenization speed, oil and nanocellulose concentration, and morphology. The emulsions were first characterized by droplet size, morphologies, and storage stability. The Design of Experiments (DoE) was used to evaluate the parameter’s effects on the emulsions’ stability, and the emulsions with optimum particle size and stability were evaluated by antimicrobial activity. The more stable emulsions required higher energy in the system to obtain efficient emulsification. The cellulose nanocrystal (CNC) emulsions showed a 30% oil volume as a constant to obtain a low creaming index (34.4% and 42.8%) and zeta potential values around −29 mV, indicating an electrostatic stabilization. The cellulose nanofiber (CNF) emulsions showed 100% stability after a month using a 20% oil volume as a constant and Zeta potential values around −15 mV, indicating a steric stabilization. CNF-emulsions’ inhibition halos for Bacilus subtilis were 30.1 ± 3.7% smaller than those found in CNC-emulsions (65 ± 2.9 mm), while Pseudomonasaeruginosas almost do not present differences in the inhibition halos. These results suggest that the nanocellulose morphology may promote a regulation on the EO migration to the medium, as well that this migration ratio does not affect the bacteria.","PeriodicalId":18775,"journal":{"name":"Natural Polysaccharides in Drug Delivery and Biomedical Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80686298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

The Influence of Intermolecular Interactions between Maleic Anhydride, Cellulose Nanocrystal, and Nisin-Z on the Structural, Thermal, and Antimicrobial Properties of Starch-PVA Plasticized Matrix 马来酸酐、纤维素纳米晶和Nisin-Z分子间相互作用对淀粉-聚乙烯醇增塑基质结构、热性能和抗菌性能的影响

Natural Polysaccharides in Drug Delivery and Biomedical Applications Pub Date : 2021-08-10 DOI: 10.3390/polysaccharides2030040

T. V. D. Oliveira, P. V. Freitas, Cicero C. Pola, L. Terra, J. O. Silva, A. T. Badaró, Nelson S. Junior, Marciano M Oliveira, R. R. Silva, N. Soares

{"title":"The Influence of Intermolecular Interactions between Maleic Anhydride, Cellulose Nanocrystal, and Nisin-Z on the Structural, Thermal, and Antimicrobial Properties of Starch-PVA Plasticized Matrix","authors":"T. V. D. Oliveira, P. V. Freitas, Cicero C. Pola, L. Terra, J. O. Silva, A. T. Badaró, Nelson S. Junior, Marciano M Oliveira, R. R. Silva, N. Soares","doi":"10.3390/polysaccharides2030040","DOIUrl":"https://doi.org/10.3390/polysaccharides2030040","url":null,"abstract":"On behalf of a circular economy, regular plastics have been replaced by biodegradable packagings. Besides, active films have been applied to improve the shelf-life and quality of foods. In this work, blends were developed using starch as a low-cost natural polymer, mixed with poly(vinyl alcohol) due to its physical-chemical and biodegradable properties. Moreover, maleic anhydride (MaAh), cellulose-nanocrystal (CN), and nisin-z (N-Z) were added, respectively, as a compatibilizer, a mechanical-reinforce, and antimicrobial agents. The thermal stability of the films was analyzed, which blends’ melting temperature occurred around 200–207 °C, and it was influenced by CN, N-Z, and MaAh amounts. N-Z and MaAh acted against S. aureus and P. aeruginosa by compound diffusion (inhibition-halo around 1.85 and 2.18 cm); while S. Choleraesuis and E. coli were inhibited by contact. Therefore, these blends presented the potential to be used as active biodegradable packaging in the food industry.","PeriodicalId":18775,"journal":{"name":"Natural Polysaccharides in Drug Delivery and Biomedical Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89161656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Rheological Characterization of the Influence of Pomegranate Peel Extract Addition and Concentration in Chitosan and Gelatin Coatings 石榴皮提取物添加量及浓度对壳聚糖和明胶涂层流变性能的影响

Natural Polysaccharides in Drug Delivery and Biomedical Applications Pub Date : 2021-08-07 DOI: 10.3390/polysaccharides2030039

Mirella Romanelli Vicente Bertolo, Rafael Leme, Virginia da Conceição Amaro Martins, A. M. de Guzzi Plepis, S. Bogusz Junior

{"title":"Rheological Characterization of the Influence of Pomegranate Peel Extract Addition and Concentration in Chitosan and Gelatin Coatings","authors":"Mirella Romanelli Vicente Bertolo, Rafael Leme, Virginia da Conceição Amaro Martins, A. M. de Guzzi Plepis, S. Bogusz Junior","doi":"10.3390/polysaccharides2030039","DOIUrl":"https://doi.org/10.3390/polysaccharides2030039","url":null,"abstract":"In this study, the effects of an agro-industrial residue with active properties, pomegranate peel extract (PPE), were evaluated on the rheological properties of potential coatings based on chitosan (C) and gelatin (G). For this, rheological properties of the polymeric solutions were investigated in relation to PPE concentration (2 or 4 mg PPE g−1 solution), and to its incorporation order into the system (in C or in CG mixture). All solutions were more viscous than elastic (G″ > G′), and the change in PPE concentration had a greater influence accentuating the viscous character of the samples in which PPE was added to the CG mixture (CGPPE2 and CGPPE4). PPE addition to the CG mixture increased the angular frequency at the moduli crossover, indicating the formation of a more resistant polymeric network. This tendency was also observed in flow results, in which PPE addition decreased the pseudoplastic behavior of the solutions, due to a greater cross-linking between the polymers and the phenolic compounds. In general, all the studied solutions showed viscosities suitable for the proposed application, and it was possible to state the importance of standardizing the addition order of the components during the preparation of a coating.","PeriodicalId":18775,"journal":{"name":"Natural Polysaccharides in Drug Delivery and Biomedical Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89307884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Polysaccharide-Based Nanoparticles for Colon-Targeted Drug Delivery Systems 用于结肠靶向药物递送系统的多糖纳米颗粒

Natural Polysaccharides in Drug Delivery and Biomedical Applications Pub Date : 2021-08-07 DOI: 10.3390/polysaccharides2030038

Y. De Anda-Flores, E. Carvajal‐Millan, A. Campa-Mada, J. Lizardi‐Mendoza, A. Rascón-Chu, J. Tánori-Córdova, A. Martínez-López

引用次数: 20

Application of Antioxidants as an Alternative Improving of Shelf Life in Foods 抗氧化剂在提高食品保质期中的应用

Natural Polysaccharides in Drug Delivery and Biomedical Applications Pub Date : 2021-07-12 DOI: 10.3390/POLYSACCHARIDES2030036

C. Leyva‐Porras, M. Román-Aguirre, Pedro Cruz-Alcantar, J. Pérez-Urizar, M. Z. Saavedra-Leos

引用次数: 9

Physical and Biodegradation Properties of Graphene Derivatives/Thermoplastic Starch Composites 石墨烯衍生物/热塑性淀粉复合材料的物理和生物降解性能

Natural Polysaccharides in Drug Delivery and Biomedical Applications Pub Date : 2021-07-06 DOI: 10.3390/POLYSACCHARIDES2030035

W. H. Ferreira, C. T. Andrade

{"title":"Physical and Biodegradation Properties of Graphene Derivatives/Thermoplastic Starch Composites","authors":"W. H. Ferreira, C. T. Andrade","doi":"10.3390/POLYSACCHARIDES2030035","DOIUrl":"https://doi.org/10.3390/POLYSACCHARIDES2030035","url":null,"abstract":"Development of biodegradable materials for packaging is an issue of the utmost importance. These materials are an alternative to petroleum-based polymers, which contribute to environment pollution after disposal. In this work, graphene oxide (GO) and glucose-reduced graphene oxide (rGO-g) were incorporated to thermoplastic starch (TPS) by melt extrusion. The TPS/GO and TPS/rGO-g composites had their physical properties and biodegradability compared. X-ray diffraction (XRD) showed that the type of graphene used led to different dispersion levels of graphene sheets, and to changes in the crystalline structure of TPS. Tensile tests carried out for the compression-molded composites indicated that TPS/rGO-g composites presented better mechanical performance. The Young’s modulus (E) increased from E = (28.6 ± 2.7) MPa, for TPS, to E = (110.6 ± 9.5) MPa and to (144.2 ± 11.2) MPa for TPS with rGO-g incorporated at 1.0 and 2.0 mass% content, respectively. The acid groups from graphene derivatives promoted glycosidic bond breakage of starch molecules and improved biodegradation of the composites. GO is well-dispersed in the TPS matrix, which contributes to biodegradation. For TPS/rGO-g materials, biodegradation was influenced by rGO-g dispersion level.","PeriodicalId":18775,"journal":{"name":"Natural Polysaccharides in Drug Delivery and Biomedical Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89957853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Application of Bacterial Cellulose in the Textile and Shoe Industry: Development of Biocomposites 细菌纤维素在纺织和制鞋工业中的应用:生物复合材料的开发

Natural Polysaccharides in Drug Delivery and Biomedical Applications Pub Date : 2021-07-02 DOI: 10.3390/POLYSACCHARIDES2030034

M. Fernandes, A. P. Souto, F. Dourado, M. Gama

{"title":"Application of Bacterial Cellulose in the Textile and Shoe Industry: Development of Biocomposites","authors":"M. Fernandes, A. P. Souto, F. Dourado, M. Gama","doi":"10.3390/POLYSACCHARIDES2030034","DOIUrl":"https://doi.org/10.3390/POLYSACCHARIDES2030034","url":null,"abstract":"Several studies report the potential of bacterial cellulose (BC) in the fashion and leather industries. This work aimed at the development of BC-based composites containing emulsified acrylated epoxidized soybean oil (AESO) that are polymerized with the redox initiator system hydrogen peroxide (H2O2) and L-ascorbic acid and ferrous sulfate as a catalyst. BC was fermented under static culture. The polymerization of the emulsified organic droplets was tested before and after their incorporation into BC by exhaustion. The composites were then finished with an antimicrobial agent (benzalkonium chloride) and dyed. The obtained composites were characterized in terms of wettability, water vapor permeability (WVP), mechanical, thermal and antimicrobial properties. When AESO emulsion was polymerized prior to the exhaustion process, the obtained composites showed higher WVP, tensile strength and thermal stability. Meanwhile, post-exhaustion polymerized AESO conferred the composite higher hydrophobicity and elongation. The composites finished with the antimicrobial agent showed activity against S. aureus. Finally, intense colors were obtained more uniformly when they were incorporated simultaneously with the emulsified AESO with all the dyes tested.","PeriodicalId":18775,"journal":{"name":"Natural Polysaccharides in Drug Delivery and Biomedical Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84916381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16