Monatshefte Fur Chemie最新文献_第7页

The evaluation of alternative method of ferrous ions assessment in pharmaceutical preparations. 药物制剂中亚铁离子评价替代方法的评价。

IF 1.8 4区化学

Monatshefte Fur Chemie Pub Date : 2018-01-01 Epub Date: 2018-02-13 DOI: 10.1007/s00706-018-2147-5

Anna Lisik, Anna Prescha, Levent E Cavlaz, Halina Grajeta, Witold Musiał

{"title":"The evaluation of alternative method of ferrous ions assessment in pharmaceutical preparations.","authors":"Anna Lisik, Anna Prescha, Levent E Cavlaz, Halina Grajeta, Witold Musiał","doi":"10.1007/s00706-018-2147-5","DOIUrl":"10.1007/s00706-018-2147-5","url":null,"abstract":"Abstract: The atomic absorption spectrometry (AAS) method is one of the most accessible procedures for ferrous ions testing in various compositions including pharmaceutical preparations. The aim of the study was to develop and partially validate analytical method which could be an excellent alternative to the routine procedure performed within dissolution studies. Electric conductivity is simple, fast, and hassle-free method. The samples during dissolution process were measured using conductivity probe in entire dissolution assessment protocol. The conductivity results were compared to data obtained from AAS. The dissolution studies were performed according to modified pharmacopoeial standards, in 900 cm3 of purified water as an acceptor medium, at 37 °C, until the achievement of an equilibrium state for every tested composition. Validity study of the developed method confirmed acceptable linearity of obtained calibration plots (r2 > 0.9553). Linearity at 100% level was found to be 100.59, 97.49, and 94.82, respectively, for drug compositions A, B, and C. Precision results were 100.45, 95.97, and 95.73, respectively, for A, B, and C, with RSD below 2% between all samples in all above mentioned formulations. The drug composition D hindered the proper validation of the method due to the high variability between samples. The method has acceptable performance features for evaluation of three of four solid drug composition containing ferrous ions.Graphical abstract: ","PeriodicalId":18766,"journal":{"name":"Monatshefte Fur Chemie","volume":"149 5","pages":"931-937"},"PeriodicalIF":1.8,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00706-018-2147-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36064556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Regiospecific formation of the nitromethyl-substituted 3-phenyl-4,5-dihydroisoxazole via [3 + 2] cycloaddition. 硝基甲基取代的3-苯基-4,5-二氢异恶唑的区域特异性形成 + 2] 环加成。

IF 1.8 4区化学

Monatshefte Fur Chemie Pub Date : 2018-01-01 Epub Date: 2018-08-20 DOI: 10.1007/s00706-018-2227-6

Barbara Mirosław, Dmytro Babyuk, Agnieszka Łapczuk-Krygier, Agnieszka Kącka-Zych, Oleg M Demchuk, Radomir Jasiński

引用次数: 19

Modifications of quinolones and fluoroquinolones: hybrid compounds and dual-action molecules. 喹诺酮类和氟喹诺酮类药物的修饰：杂化化合物和双作用分子。

IF 1.8 4区化学

Monatshefte Fur Chemie Pub Date : 2018-01-01 Epub Date: 2018-06-07 DOI: 10.1007/s00706-018-2215-x

Joanna Fedorowicz, Jarosław Sączewski

引用次数: 0

Progress in the synthesis of δ-sultones. δ-硫酮的合成研究进展。

IF 1.8 4区化学

Monatshefte Fur Chemie Pub Date : 2018-01-01 Epub Date: 2017-07-15 DOI: 10.1007/s00706-017-2010-0

Christina Gaunersdorfer, Mario Waser

引用次数: 3

Novel naphthylpyridines from cobalt-catalyzed cyclotrimerization of a chiral diyne. 由钴催化手性二炔环三聚反应合成的新型萘基吡啶。

IF 1.8 4区化学

Monatshefte Fur Chemie Pub Date : 2018-01-01 Epub Date: 2017-11-28 DOI: 10.1007/s00706-017-2083-9

Volkmar Trommer, Fabian Fischer, Marko Hapke

引用次数: 6

Palladium complexes containing imino phenoxide ligands: synthesis, luminescence, and their use as catalysts for the ring-opening polymerization of rac-lactide. 含有亚氨基苯氧配体的钯配合物：合成、发光及其用作 rac-内酰胺开环聚合的催化剂。

IF 1.8 4区化学

Monatshefte Fur Chemie Pub Date : 2018-01-01 Epub Date: 2017-12-12 DOI: 10.1007/s00706-017-2119-1

Mrinmay Mandal, Manuela List, Ian Teasdale, Günther Redhammer, Debashis Chakraborty, Uwe Monkowius

引用次数: 0

Complementary use of GCxGC-TOF-MS and statistics for differentiation of variety in biosolid samples. 互补使用GCxGC-TOF-MS和统计学对生物固体样品的多样性进行鉴别。

IF 1.8 4区化学

Monatshefte Fur Chemie Pub Date : 2018-01-01 Epub Date: 2018-08-09 DOI: 10.1007/s00706-018-2221-z

Hubert Byliński, Tomasz Dymerski, Jacek Gębicki, Jacek Namieśnik

引用次数: 12

Rapid assessment of the authenticity of limequat fruit using the electronic nose and gas chromatography coupled with mass spectrometry. 利用电子鼻和气相色谱-质谱联用技术快速鉴定枸杞果实的真伪。

IF 1.8 4区化学

Monatshefte Fur Chemie Pub Date : 2018-01-01 Epub Date: 2018-08-09 DOI: 10.1007/s00706-018-2242-7

Martyna Lubinska-Szczygeł, Dominika Pudlak, Tomasz Dymerski, Jacek Namieśnik

{"title":"Rapid assessment of the authenticity of limequat fruit using the electronic nose and gas chromatography coupled with mass spectrometry.","authors":"Martyna Lubinska-Szczygeł, Dominika Pudlak, Tomasz Dymerski, Jacek Namieśnik","doi":"10.1007/s00706-018-2242-7","DOIUrl":"https://doi.org/10.1007/s00706-018-2242-7","url":null,"abstract":"Abstract: Citrus fruits are very popular food products. There are many species and varieties of them. There are also documented cases of some citrus fruits causing a severe allergic reaction. Some species of the citrus fruits, especially hybrid ones show a reduced allergenic effect due to the lack of seeds. There is a need for rapid methods for evaluation of citrus' botanical origin. During research, the headspace of three citrus fruits Citrus Aurantifolia, Citrus japonica, and Citrus × floridana was analysed using electronic nose based on ultrafast gas chromatography and gas chromatography with mass spectrometry. In the paper, two approaches were compared. The usefulness of an electronic nose to control the quality of hybrids was demonstrated. The results obtained during ultrafast gas chromatography analyses were subjected to statistical analysis. Four chemometric methods namely: principal component analysis (PCA), discriminant function analysis (DFA), soft independent modeling of class analogies (SIMCA), statistical quality control (SQC) were used to distinguish between limequat and its parent fruits. Electronic nose combined with chemometrics is a novel analytical tool for hybrid fruits' classification due to their botanical origin. It can supplement established techniques by providing results in a short time and at a low cost.Graphical abstract: ","PeriodicalId":18766,"journal":{"name":"Monatshefte Fur Chemie","volume":"149 9","pages":"1605-1614"},"PeriodicalIF":1.8,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00706-018-2242-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36455426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Analysis of volatile fraction of sweetie (Citrus maxima × Citrus paradisi) and its parent fruit using proton transfer reaction mass spectrometry. 质子转移反应质谱法分析甜桔及其亲本果实挥发性成分。

IF 1.8 4区化学

Monatshefte Fur Chemie Pub Date : 2018-01-01 Epub Date: 2018-08-09 DOI: 10.1007/s00706-018-2229-4

Anna Różańska, Dorota Sieńska, Tomasz Dymerski, Jacek Namieśnik

{"title":"Analysis of volatile fraction of sweetie (Citrus maxima × Citrus paradisi) and its parent fruit using proton transfer reaction mass spectrometry.","authors":"Anna Różańska, Dorota Sieńska, Tomasz Dymerski, Jacek Namieśnik","doi":"10.1007/s00706-018-2229-4","DOIUrl":"https://doi.org/10.1007/s00706-018-2229-4","url":null,"abstract":"Abstract: The quality of the fruit is affected by several main ingredients and the aroma plays a fundamental role during the selection of fruit by consumers. In the case where several fruit have similar aromas and only one of them has specific health properties, it is very important to find the differences in the volatile organic compounds (VOCs) composition to distinguish these samples. Such situations are often found for hybrid fruit. Sweetie is a hybrid of grapefruit and pummelo. Sweetie fruit is characterized by high antioxidant potential and a positive effect on human health. The aim of this study was to verify the unique volatile compositional traits of three species of citrus fruit. Proton transfer reaction Time-of-Flight mass spectrometry (PTR-TOF-MS) was utilized to obtain the mass-resolved fingerprints of VOCs. The chemical formula of these VOC masses was tentatively identified. Principal component analysis was performed to evaluate the differences between the groups.Graphical abstract: ","PeriodicalId":18766,"journal":{"name":"Monatshefte Fur Chemie","volume":"149 9","pages":"1629-1634"},"PeriodicalIF":1.8,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00706-018-2229-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36455428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Low temperature heat capacities and thermodynamic functions described by Debye-Einstein integrals. 用德拜-爱因斯坦积分描述的低温热容和热力学函数。

IF 1.8 4区化学

Monatshefte Fur Chemie Pub Date : 2018-01-01 Epub Date: 2018-01-25 DOI: 10.1007/s00706-017-2117-3

Ernst Gamsjäger, Manfred Wiessner

{"title":"Low temperature heat capacities and thermodynamic functions described by Debye-Einstein integrals.","authors":"Ernst Gamsjäger, Manfred Wiessner","doi":"10.1007/s00706-017-2117-3","DOIUrl":"https://doi.org/10.1007/s00706-017-2117-3","url":null,"abstract":"Abstract: Thermodynamic data of various crystalline solids are assessed from low temperature heat capacity measurements, i.e., from almost absolute zero to 300 K by means of semi-empirical models. Previous studies frequently present fit functions with a large amount of coefficients resulting in almost perfect agreement with experimental data. It is, however, pointed out in this work that special care is required to avoid overfitting. Apart from anomalies like phase transformations, it is likely that data from calorimetric measurements can be fitted by a relatively simple Debye-Einstein integral with sufficient precision. Thereby, reliable values for the heat capacities, standard enthalpies, and standard entropies at T = 298.15 K are obtained. Standard thermodynamic functions of various compounds strongly differing in the number of atoms in the formula unit can be derived from this fitting procedure and are compared to the results of previous fitting procedures. The residuals are of course larger when the Debye-Einstein integral is applied instead of using a high number of fit coefficients or connected splines, but the semi-empiric fit coefficients keep their meaning with respect to physics. It is suggested to use the Debye-Einstein integral fit as a standard method to describe heat capacities in the range between 0 and 300 K so that the derived thermodynamic functions are obtained on the same theory-related semi-empiric basis. Additional fitting is recommended when a precise description for data at ultra-low temperatures (0-20 K) is requested.Graphical abstract: ","PeriodicalId":18766,"journal":{"name":"Monatshefte Fur Chemie","volume":"149 2","pages":"357-368"},"PeriodicalIF":1.8,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00706-017-2117-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35876773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20