Minerva ginecologica最新文献

{"title":"The role of the sentinel lymph node in vulvar cancer.","authors":"Andrea Giannini,&nbsp;Ottavia D'''''Oria,&nbsp;Giusi Santangelo,&nbsp;Carlo M Allegrini,&nbsp;Giuseppe Caruso,&nbsp;Anna Di Pinto,&nbsp;Giorgia Perniola,&nbsp;Innocenza Palaia,&nbsp;Marco Monti,&nbsp;Ludovico Muzii,&nbsp;Pierluigi Benedetti Panici,&nbsp;Violante Di Donato","doi":"10.23736/S0026-4784.20.04601-8","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04601-8","url":null,"abstract":"<p><p>The aim of this study was to update clinical practice applications and technical procedures regarding sentinel lymph node (SLN) biopsy in vulvar cancer considering European experts' opinions from this field. Systematic data search performed using PubMed/medline database up to May 20, 2020. Focus was only for English language publications of original studies on SLN biopsy in vulvar cancer. Given the basis of published evidence and the consensus of European experts, this study provides an updated overview on clinical applications and technical procedures of SLN biopsy in vulvar cancer. In early-stage vulvar cancer patients with a negative sentinel node the groin recurrence rate is low, survival is excellent, and treatment-related morbidity is minimal. We advise that sentinel node dissection, performed by a quality-controlled multidisciplinary team, should be part of the standard treatment in selected patients with early-stage vulvar cancer.</p>","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 6","pages":"361-366"},"PeriodicalIF":1.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38170977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pelvic floor ultrasonography for the evaluation of the rectum-vaginal septum before and after prolapse native-tissue repair.","authors":"Marta Barba,&nbsp;Matteo Frigerio,&nbsp;Stefano Manodoro","doi":"10.23736/S0026-4784.20.04620-1","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04620-1","url":null,"abstract":"","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 6","pages":"426-428"},"PeriodicalIF":1.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38221759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinicopathological effects of body composition measurements for patients with endometrial cancer.","authors":"Christopher G Smith,&nbsp;Deepti Sharma,&nbsp;Hagen Smith,&nbsp;Shelley Zippay,&nbsp;Liza Bastin,&nbsp;Luis Acosta-Briceno,&nbsp;James Lee,&nbsp;Brent Shelton,&nbsp;Justin Gorski,&nbsp;Anthony Mcdowell,&nbsp;Brian Burgess,&nbsp;Tricia Fredericks,&nbsp;Rachel Miller,&nbsp;Christopher Desimone,&nbsp;Charles Dietrich,&nbsp;Holly Gallion,&nbsp;Frederick Ueland,&nbsp;Edward Pavlik,&nbsp;John Vannagell,&nbsp;Lauren Baldwin","doi":"10.23736/S0026-4784.20.04629-8","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04629-8","url":null,"abstract":"","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 6","pages":"430-435"},"PeriodicalIF":1.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38199306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fertility and pregnancy outcomes following hysteroscopic metroplasty of uterine septa: an update.","authors":"J. Carugno, L. Alonso","doi":"10.23736/S0026-4784.20.04724-3","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04724-3","url":null,"abstract":"The septate uterus is still a matter of debate and discussion today in different medical forums. The controversy is divided between 2 different quite divergent opinions, on the one hand that of those who promote its surgical correction and on the other that of those who advocate expectant management with no recommended surgical intervention. It is extremely difficult to determine the association between septum and infertility. Infertility is a multifactorial condition, furthermore, the mechanism by which the septate uterus is associated with infertility is still unknown, although the most probable causes seem to be related to implantation alterations. There is lack of high quality randomized controlled studies with an adequate number of patients demonstrating the efficacy of the surgical treatment of patients with septated uterus. However, the limited available data based on observational studies, support minimally invasive treatment using hysteroscopy as the method of choice for the treatment of patients with septated uterus and history of infertility or poor obstetrical outcomes.","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49661141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of SARS-CoV-2 infection in the obstetric population before the hospital admission.","authors":"Massimo Franchi,&nbsp;Mariachiara Bosco,&nbsp;Beatrice Barbieri,&nbsp;Erica Diani,&nbsp;Giuliana Lo Cascio,&nbsp;Antonio S Laganà,&nbsp;Jvan Casarin,&nbsp;Simone Garzon,&nbsp;Marina Sangaletti","doi":"10.23736/S0026-4784.20.04654-7","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04654-7","url":null,"abstract":"","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 6","pages":"429-430"},"PeriodicalIF":1.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38413959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors associated with bladder injury at the time of cesarean hysterectomy for placenta accreta.","authors":"Felice Crocetto,&nbsp;Sonia Migliorini,&nbsp;Elena Cancelliere,&nbsp;Enrica Mastantuoni,&nbsp;Gabriele Saccone,&nbsp;Gennaro Cancelmo,&nbsp;Francesco Trama,&nbsp;Paolo Verrazzo,&nbsp;Antonia Giudicepietro,&nbsp;Fulvio Zullo","doi":"10.23736/S0026-4784.20.04611-0","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04611-0","url":null,"abstract":"","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 6","pages":"425-426"},"PeriodicalIF":1.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38221757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of sentinel lymph node mapping in endometrial carcinoma.","authors":"Alejandro Soderini,&nbsp;Valeria Depietri,&nbsp;Martin Crespe,&nbsp;Yanina Rodriguez,&nbsp;Alejandro Aragona","doi":"10.23736/S0026-4784.20.04626-2","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04626-2","url":null,"abstract":"<p><p>Endometrial cancer is the most commonly diagnosed gynecological malignancy in developing countries, and the second malignancy after cervical cancer in developing countries. The primary treatment is based on surgical and pathologic staging including extrafascial type A radical hysterectomy bilateral salpingo-oophorectomy and pelvic and latero-aortic lymphadenectomy. Minimally invasive surgery is the most widely used technique. Sentinel node biopsy is part of this concept and has reached the management of endometrial cancer. The aim of this review was to describe the history, the different injection techniques and results of sentinel node biopsy, and analyze the future role of this technique in endometrial carcinoma.</p>","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 6","pages":"367-383"},"PeriodicalIF":1.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38471913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sentinel lymph node in cervical cancer: a literature review on the use of conservative surgery techniques.","authors":"Francesco Plotti,&nbsp;Giuseppe Messina,&nbsp;Corrado Terranova,&nbsp;Roberto Montera,&nbsp;Carlo De Cicco Nardone,&nbsp;Federica Guzzo,&nbsp;Daniela Luvero,&nbsp;Alessandra Gatti,&nbsp;Teresa Schirò,&nbsp;Gianmarco Rossini,&nbsp;Cristiana De Luca,&nbsp;Fernando Ficarola,&nbsp;Laura Feole,&nbsp;Roberto Angioli","doi":"10.23736/S0026-4784.20.04634-1","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04634-1","url":null,"abstract":"<p><strong>Introduction: </strong>Sentinel lymph node detection is a surgical procedure that allow to avoid systematic lymphadenectomy in those tumors in early stage where lymph node spread is not sure. If the sentinel lymph node is not involved by tumor in 98-99% of case other lymph nodes are clean. The reason why less radical surgery is chosen is linked to the lower postoperative morbidity rate, the risk of lower limb lymphedema decreases. The aim of this review was to summarize what is the state of art of using the sentinel lymph node dissection (SLD) technique and what are the future goals to improve the safety and the reliability.</p><p><strong>Evidence acquisition: </strong>We have conducted a review of the literature of the past 10 years to understand the attitudes of oncologist gynecologists in the world to the conservative treatment of cervical cancer. We only selected articles from 2010 onwards, which meet the inclusion criteria.</p><p><strong>Evidence synthesis: </strong>The detection rate varies from 83% to 100%. The bilateral detection rate, on the other hand, varies from 42% to 100%. The false negative rate ranges from 4% to 12%. Sensitivity varies from 20.7% (considering the frozen section) to 100%.</p><p><strong>Conclusions: </strong>Indocyanine green is the most reliable and performing tracer for the search of the sentinel lymph node; that the false intraoperative negative rate is too high to be sure not to subject the patient to an incorrect therapeutic procedure; data concerning the safety and survival of conservative lymphadenectomy (SLND) compared to systematic lymphadenectomy are still lacking in the literature and therefore we are awaiting the results of the two ongoing randomized clinical trials that will allow us to have more significant scientific data.</p>","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 6","pages":"391-398"},"PeriodicalIF":1.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38341345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High grade cervical intraepithelial neoplasia positive biopsy: the importance of accurate pre-operative workup.","authors":"Cecilia Bussani,&nbsp;Francesca Malentacchi,&nbsp;Karin L Andersson,&nbsp;Massimiliano Fambrini,&nbsp;Chiara Coco,&nbsp;Dora Pavone,&nbsp;Giulia Fantappiè,&nbsp;Irene Turrini,&nbsp;Valeria Dubini,&nbsp;Felice Petraglia,&nbsp;Flavia Sorbi","doi":"10.23736/S0026-4784.20.04587-6","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04587-6","url":null,"abstract":"<p><strong>Background: </strong>In cervical cancer screening programs, women with abnormal cytology and confirmation by biopsy are referred for colposcopy for histological evaluation.</p><p><strong>Methods: </strong>We characterized the presence and the genotype of HPV by Linear Array HPV genotyping assay in cytological samples collected from about 400 women undergoing conization, with reported high CIN grade after biopsy.</p><p><strong>Results: </strong>The most prevalent genotype was HPV 16, with an increasing presence depending on the severity of the CIN and with the highest incidence in the 26-35 age range. In the group of younger women (<25) we found the highest percentage of CIN3 (39.3%) and the lowest of CIN1 (17.9%). An increase of CIN1 with increasing age was observed. A different distribution of HPV presence was observed depending on CIN grade (P<0.001): CIN1 HPV negative samples were 46.3%, CIN2: 5.8% and CIN3: 1.4%. Interesting, in the analyzed cohort, we observed the presence of 30% of CIN1. Moreover, within CIN1, 85% of them were associated to negative HPV detection, this observation suggested that the detection of HPV presence may be useful to identify low CIN grade that should be reconsidered for surgical treatment.</p><p><strong>Conclusions: </strong>These findings suggest implementing the protocol for the management of women with high risk precancer lesions, with a further HPV test before surgical treatment. The evaluation of HPV presence and genotype before conization might represent a useful tool in reducing or postpone the conization treatment.</p>","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 6","pages":"413-419"},"PeriodicalIF":1.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38792197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy of hysteroscopy, ultrasound and magnetic resonance imaging in detecting congenital uterine anomalies.","authors":"L. Alonso, J. Carugno, L. Nappi","doi":"10.23736/S0026-4784.20.04723-1","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04723-1","url":null,"abstract":"","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46382684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}