Minerva ginecologica最新文献_第3页

The role of sentinel lymph node mapping in lower genital tract melanoma. 下生殖道黑色素瘤前哨淋巴结定位的作用。

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Minerva ginecologica Pub Date : 2020-12-01 Epub Date: 2020-08-03 DOI: 10.23736/S0026-4784.20.04628-6

Salvatore Lopez, Rocco Guerrisi, Claudia Brusadelli, Giorgio Bogani, Antonino Ditto, Francesco Raspagliesi

{"title":"The role of sentinel lymph node mapping in lower genital tract melanoma.","authors":"Salvatore Lopez, Rocco Guerrisi, Claudia Brusadelli, Giorgio Bogani, Antonino Ditto, Francesco Raspagliesi","doi":"10.23736/S0026-4784.20.04628-6","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04628-6","url":null,"abstract":"Introduction: Vulvar and vaginal melanomas are rare cancers of the female genital tract and account for 1% to 3% of all melanomas diagnosed in women. Due to the rarity of the disease, few data are available on the clinical and pathologic features of these cancers. Furthermore, treatment options are generally based on extrapolations of the information available for the more common cutaneous counterparts. Surgery represents the mainstay of treatment for lower genital tract melanoma. Moreover, the role of sentinel lymph node (SLN) assessment is controversial because no prospective data are available.Evidence acquisition: Data were collected from Medline, Embase, Web of Sciences and Scopus databases. On July 10, 2020, we used the search comprising the terms \"vulvar melanoma,\" \"genital melanoma\" and \"vulvovaginal melanoma\" including only studies in which SLN biopsy was performed.Evidence synthesis: Ten retrospective studies have been found. No randomized trials have been reported. The studies included 132 patients while only 63 (47%) undergone SLN. 99mTC with or without blue dye followed by ultrastaging was highly accurate and is currently the gold standard. Mean detection rate was 98.3%. No clear evidence supported the execution of back lymphadenectomy (after SLN mapping), in fact, extrapolating data from cutaneous melanomas of other sites, completion of lymphadenectomy does not confer a melanoma-specific survival advantage.Conclusions: Although the small amount of available data, sentinel lymph node procedure is feasible and capable of identifying patients who have occult lymph node metastases. However, the potential role of the sentinel lymph node procedure as an alternative method of lymph node staging in patients with vulvar or vaginal melanoma needs further investigation.","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 6","pages":"384-390"},"PeriodicalIF":1.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38229836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Update on new imaging technologies in sentinel node detection. 前哨淋巴结检测新成像技术的最新进展。

IF 1

Minerva ginecologica Pub Date : 2020-12-01 Epub Date: 2020-12-11 DOI: 10.23736/S0026-4784.20.04707-3

Silvia Pelligra, Giuseppe Scaletta, Stefano Cianci, Salvatore Gueli Alletti, Stefano Restaino, Anna Fagotti, Giovanni Scambia, Francesco Fanfani

{"title":"Update on new imaging technologies in sentinel node detection.","authors":"Silvia Pelligra, Giuseppe Scaletta, Stefano Cianci, Salvatore Gueli Alletti, Stefano Restaino, Anna Fagotti, Giovanni Scambia, Francesco Fanfani","doi":"10.23736/S0026-4784.20.04707-3","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04707-3","url":null,"abstract":"In most cancers, lymph node status is the most critical factor impacting the evolution of the disease and the overall survival. Identifying potential nodal metastasis allows the oncologist to adjust the stage and, consequently, the patient's treatment. For this reason, a precise evaluation of the regional nodes is mandatory. In gynecological cancers, pelvic, paraaortic, and inguinal nodes are the region most frequently interested by metastasis. In the past years, comprehensive lymphadenectomy was the standard of care for endometrial, cervical, ovarian, and vulvar cancers. However, after introducing the sentinel lymph node (SNL) biopsy in breast cancers, this technique has gained much more interest in gynecology oncology. Several studies have shown that SLN allows an evaluation of the node status without the complications related to the lymphadenectomy that impacts the patient's quality of life. In this review, we discuss the role of SNL biopsy in gynecological cancers and the technique's evolution over the years. Moreover, we debate the OSNA method for SLN analysis that is recently introduced for uterine cancer.","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 6","pages":"404-412"},"PeriodicalIF":1.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38703089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The role of sentinel-node biopsy in ovarian cancer. 前哨淋巴结活检在卵巢癌中的作用。

IF 1

Minerva ginecologica Pub Date : 2020-12-01 Epub Date: 2020-11-03 DOI: 10.23736/S0026-4784.20.04691-2

Pawel Mach, Rainer Kimmig, Paul Buderath

{"title":"The role of sentinel-node biopsy in ovarian cancer.","authors":"Pawel Mach, Rainer Kimmig, Paul Buderath","doi":"10.23736/S0026-4784.20.04691-2","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04691-2","url":null,"abstract":"Lymph node involvement is an important prognostic factor in early and advanced epithelial ovarian cancer (EOC). However, to date there is no reliable method of detecting lymph node involvement, apart from surgical staging. Thus, pelvic and paraaortic lymphadenectomy (LNE) are still part of standard surgery of early ovarian cancer. There is conflicting evidence about the therapeutic value of systematic LNE in early EOC. Thus, the developmemt of a method to predict nodal status accurately, without extensive LNE, is the subject of ongoing research. Sentinel lymphadenectomy (SLN) has become a standard procedure in oncological surgery. However, SLN is not yet an established and widely accepted procedure for EOC. This review aimed at summarizing available evidence on its feasibility and reliability in EOC. Overall, evidence of SLN in early EOC is still scarce. So far, only small series of patients with a variety of tracers and injection sites were published. From the available literature, the most promising technique seems to be injection into the infundibulopelvic, as well as the proper ovarian ligament. Indocyanine green seems to be an excellent tracer for successful SLN of ovarian tumors, which can be used during laparoscopic or robotic surgery. The detection rates and true positive rates of studies support further investigation of the technique. Results from prospective studies, e.g. the ongoing SELLY trial, are necesssary to implement SLN into the standard treatment of early EOC.","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":"72 6","pages":"399-403"},"PeriodicalIF":1.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38664041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The role of sentinel node in gynecologic malignancies. 前哨淋巴结在妇科恶性肿瘤中的作用。

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Minerva ginecologica Pub Date : 2020-12-01 Epub Date: 2020-09-03 DOI: 10.23736/S0026-4784.20.04637-7

Francesco Plotti, Roberto Angioli

引用次数: 0

Tailoring parametrectomy for early cervical cancer (Stage IA-IIA FIGO): a review on surgical, oncologic outcome and sexual function. 早期癌症的定制子宫旁切除术（IA-IIA阶段FIGO）：手术、肿瘤结果和性功能的回顾。

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Minerva ginecologica Pub Date : 2020-11-30 DOI: 10.23736/S0026-4784.20.04683-3

F. Plotti, F. Ficarola, G. Messina, C. Terranova, R. Montera, F. Guzzo, C. De Cicco Nardone, Gianmarco Rossini, T. Schiró, Alessandra Gatti, D. Luvero, L. Feole, R. Angioli

{"title":"Tailoring parametrectomy for early cervical cancer (Stage IA-IIA FIGO): a review on surgical, oncologic outcome and sexual function.","authors":"F. Plotti, F. Ficarola, G. Messina, C. Terranova, R. Montera, F. Guzzo, C. De Cicco Nardone, Gianmarco Rossini, T. Schiró, Alessandra Gatti, D. Luvero, L. Feole, R. Angioli","doi":"10.23736/S0026-4784.20.04683-3","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04683-3","url":null,"abstract":"INTRODUCTION\u0000Cervical cancer is currently one of the most common cancers afflicting the female population worldwide and in industrialized countries the presence of screening and a specific diagnostic and therapeutic process has favored early diagnosis of cervical cancer. In literature have found that reducing the radicality on the parametria in early cervical cancer (ECC), reduces complications without impacting oncological outcomes, but the data in the literature are not yet clear.\u0000\u0000\u0000EVIDENCE ACQUISITION\u0000Searching on Pubmed we included 1473 articles from January 1974 to 2020. We identified all the studies that compared different type of radical hysterectomy in the primary surgical treatment of ECC. 16 articles were elected for the review.\u0000\u0000\u0000EVIDENCE SYNTHESIS\u0000Modified radical hysterectomy (Piver II /Querleu-Morrow Type B) in ECC, if compared to CRH (Piver III / Querleu-Morrow Type C2), is not associated with worse cancer outcome and patient survival, but it is associated with a minor operating time, lower blood loss and minor bladder dysfunction. Nerve sparing radical hysterectomy approach (NSRH/ Querleu-Morrow Type C1) compared to CRH (Piver III / Type C2) in the ECC, with our data we can confirm a noninferiority regarding the oncological outcome.\u0000\u0000\u0000CONCLUSIONS\u0000Reduced radicality on the parametrium offers positive effects on the quality of life (sexual life and bladder function) of patients without impacting on survival, oncological outcome.","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2020-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44729643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Pregnant woman infected by Coronavirus Disease (COVID-19) and calcifications of the fetal bowel and gallbladder: a case report. 孕妇感染冠状病毒疾病（新冠肺炎）和胎儿肠道和胆囊钙化：病例报告。

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Minerva ginecologica Pub Date : 2020-11-30 DOI: 10.23736/S0026-4784.20.04717-6

F. G. Sileo, A. Tramontano, Chiara Leone, M. Meacci, W. Gennari, G. Ternelli, A. La Marca, L. Lugli, A. Berardi, F. Facchinetti, E. Bertucci

{"title":"Pregnant woman infected by Coronavirus Disease (COVID-19) and calcifications of the fetal bowel and gallbladder: a case report.","authors":"F. G. Sileo, A. Tramontano, Chiara Leone, M. Meacci, W. Gennari, G. Ternelli, A. La Marca, L. Lugli, A. Berardi, F. Facchinetti, E. Bertucci","doi":"10.23736/S0026-4784.20.04717-6","DOIUrl":"https://doi.org/10.23736/S0026-4784.20.04717-6","url":null,"abstract":"INTRODUCTION\u0000COVID-19 was declared pandemic due to the rapid increase of cases around the world, including the number of pregnant women. Data about vertical transmission of Covid-19 are still limited and controversial: in most cases, although a positive mother, the virus could not be isolated in amniotic fluid, cord blood, breast milk or neonatal throat swab in these patients. No data have been published about possible intrauterine sonographic signs of infection.\u0000\u0000\u0000CASE PRESENTATION\u0000A pregnant woman was diagnosed with SARS-CoV2 at 35+5 weeks of gestation and managed conservatively at home. At transabdominal ultrasound at 38+3 weeks, fetal bowel and gallbladder calcifications were noted. CMV and other infectious agents were ruled out; an iterative Caesarean Section was performed at 38+5 weeks without complications. Placenta resulted negative for SARS-CoV-2; the umbilical cord blood sample was IgG positive and IgM negative as per maternal infection. The baby developed respiratory distress syndrome requiring endotracheal surfactant administration and nasal-CPAP for one day but nasopharyngeal swabs at birth and after 48 hours were SARS-Cov2 negative. Neonatal abdominal ultrasound showed normal liver, acalculous gallbladder with mild parietal thickening. The baby was discharged in good conditions.\u0000\u0000\u0000CONCLUSIONS\u0000although gallbladder calcifications and echogenic bowel are highly suspicious of viral infection and were thought to be due to the vertical transmission of SARS-CoV-2, these findings were not corroborated by the results of our diagnostic tests; these sonographic findings might represent a false positive of fetal infection in mother affected by COVID-19 since vertical transmission appears to be rare.","PeriodicalId":18745,"journal":{"name":"Minerva ginecologica","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2020-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49572080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

STAN: a reappraisal of its clinical usefulness. STAN:对其临床用途的重新评估。

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Minerva ginecologica Pub Date : 2020-11-30 DOI: 10.23736/S0026-4784.20.04690-0

G. Cagninelli, A. Dall'asta, E. di Pasquo, G. Morganelli, V. Degennaro, S. Fieni, T. Frusca, T. Ghi

引用次数: 1

Greetings from the new Editor-in-Chief. 新任总编辑向您问好。

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Minerva ginecologica Pub Date : 2020-11-30 DOI: 10.23736/S0026-4784.20.04746-2

A. La Marca

引用次数: 0

Hysteroscopic approach to uterine cervical canal stenosis. 宫腔镜入路治疗宫颈管狭窄。

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Minerva ginecologica Pub Date : 2020-11-30 DOI: 10.23736/S0026-4784.20.04729-2

B. Zizolfi, V. Foreste, A. Cammarota, A. Manzi, A. Gallo, A. Di Spiezio Sardo

引用次数: 0

Obstetric anal sphincter injuries: strategies for prevention, diagnosis, and management. 产科肛门括约肌损伤：预防、诊断和管理策略。

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Minerva ginecologica Pub Date : 2020-11-30 DOI: 10.23736/S0026-4784.20.04668-7

A. Seidenari, D. Cuicchi, A. Youssef, Emily A. Oliver, E. Montaguti, F. Bellussi

引用次数: 1