Minerva medica最新文献_第5页

Incidence and risk factors for non-cardiac syncope in a cohort of patients addressing an accredited Arterial Hypertension Center: the Innocent Study. 在经认可的动脉高血压中心就诊的一组患者中，非心源性晕厥的发生率和风险因素：无辜者研究。

IF 4.7 4区医学

Minerva medica Pub Date : 2024-04-01 DOI: 10.23736/S0026-4806.24.09200-0

F. Numeroso, Luca Bottaro, Ali Younes, Andrea Ungar, A. Cabassi

{"title":"Incidence and risk factors for non-cardiac syncope in a cohort of patients addressing an accredited Arterial Hypertension Center: the Innocent Study.","authors":"F. Numeroso, Luca Bottaro, Ali Younes, Andrea Ungar, A. Cabassi","doi":"10.23736/S0026-4806.24.09200-0","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09200-0","url":null,"abstract":"BACKGROUND\u0000Hypotensive susceptibility in hypertensive patients could facilitate orthostatic hypotension, syncope and fall. The aim of this study was to identify incidence, clinical form, complications and risk factors for non-cardiac syncope in a cohort of hypertensive patients.\u0000\u0000\u0000METHODS\u0000This is an observational, case-controlled, retrospective study carried out on 168 patients, evaluated at the Hypertension Center of the University Hospital of Parma (Italy). Based on the presence of episodes of syncope during the six months prior to enrolment, we identified cases and controls and then we compared them to personal data, comorbidities, current drug regimens, presence of orthostatic hypotension, office and ambulatory blood pressure monitoring (ABPM) blood pressure (BP) values.\u0000\u0000\u0000RESULTS\u0000In patients with previous syncopal episodes (29.8% of total), we more frequently found female gender, comorbidities associated with autonomic dysfunction, diuretics and non-CV drugs potentially associated with hypotension in their current drug regimen, orthostatic hypotension and lower office and ABPM BP values.\u0000\u0000\u0000CONCLUSIONS\u0000To identify hypertensive patients at higher risk for syncope and falls, physicians should focus on comorbidities and current drug regimens, systematically perform an active standing test to identify orthostatic hypotension, employ ABPM to compare BP values with the pre-established target and highlight systolic BP drops and abnormalities suggesting concomitant autonomic dysfunction. The modulation of antihypertensive therapy is an effective tool to counteract the risk of non-cardiac syncope, with possible trauma or other negative influences.","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":"107 ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140758877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical efficacy of comprehensive rehabilitation therapy for postoperative elbow joint dysfunction in upper limb fracture. 综合康复治疗对上肢骨折术后肘关节功能障碍的临床疗效。

IF 4.7 4区医学

Minerva medica Pub Date : 2024-02-01 Epub Date: 2023-06-29 DOI: 10.23736/S0026-4806.23.08729-3

Yao Pang, Yu Gu, Jianfeng Wang

引用次数: 0

Clinical efficacy and mechanism exploration of Tianma Gouteng decoction in improving gestational hypertension by regulating IL-6, NF-kB, and AngII. 天麻钩藤汤通过调节IL-6、NF-kB和AngII改善妊娠高血压的临床疗效及机制探讨

IF 4.7 4区医学

Minerva medica Pub Date : 2024-02-01 Epub Date: 2023-07-24 DOI: 10.23736/S0026-4806.23.08788-8

Shujun Zhao, Xiao Sun, Rui Xu, Yaqin Wang, Muchen Zhang, Yuchen Sun, Yan Zhang

引用次数: 0

The effect of cognitive behavioral therapy on disease recovery and medication adherence in first-episode schizophrenia patient. 认知行为疗法对首发精神分裂症患者疾病康复和坚持服药的影响。

IF 4.7 4区医学

Minerva medica Pub Date : 2024-02-01 Epub Date: 2023-06-20 DOI: 10.23736/S0026-4806.23.08751-7

Ziming Xu, Shengyi Rao, Pei Xu, Tiancheng Jia, Jianfang Li, Ye Zheng

引用次数: 0

Clinical study on the efficacy of self-designed elimination soup in the accumulation of qi stagnation and blood stasis based on transient elasticity of liver and spleen. 基于肝脾瞬时弹性的自拟消积汤对气滞血瘀证疗效的临床研究。

IF 4.7 4区医学

Minerva medica Pub Date : 2024-02-01 Epub Date: 2023-07-13 DOI: 10.23736/S0026-4806.23.08787-6

Xinfeng Huang, Lina Xu, Yurong Li, Mingyue Song, Dongwang Zhan

引用次数: 0

Blood gas analysis changes and body position in patients with pneumonia due to SARS-CoV-2. SARS-COV-2 肺炎患者的血气分析变化和体位：一项试验性研究。

IF 4.7 4区医学

Minerva medica Pub Date : 2024-02-01 Epub Date: 2021-02-22 DOI: 10.23736/S0026-4806.21.07171-8

Alessandro DI Marco Berardino, Federica Sambuco, Francesco Travaglino, Antonina Re, Emanuele Gilardi

引用次数: 0

Pulmonary artery denervation significantly improves right ventricular longitudinal strain in pulmonary hypertension induced by dehydromonocrotaline. 肺动脉去神经化能明显改善脱水木菠萝碱诱发的肺动脉高压的右心室纵向应变。

IF 4.7 4区医学

Minerva medica Pub Date : 2024-02-01 Epub Date: 2022-07-05 DOI: 10.23736/S0026-4806.22.08259-3

Jing Dong, Xiao-Min Jiang, Juan Zhang, Du-Jiang Xie, Jie Luo, Hong Ran, Lin Li, Miao Li, Ling Zhou, Ping-Yang Zhang

引用次数: 0

Clinical efficacy and application value of comprehensive internal fixation surgery for complex ankle fracture patients. 复杂踝关节骨折患者综合内固定手术的临床疗效和应用价值。

IF 4.7 4区医学

Minerva medica Pub Date : 2024-02-01 Epub Date: 2023-08-03 DOI: 10.23736/S0026-4806.23.08813-4

Xingzhou Zhang, Peng Xu, Bing Li, Wenke Zhu, Junfeng Bao, Chuan Jia, Zhipeng Qian, Yabing Yuan

引用次数: 0

Application of fiberoptic bronchoscopy assisted local injection of budesonide in improving the prognosis of severe pneumonia. 应用纤维支气管镜辅助局部注射布地奈德改善重症肺炎的预后。

IF 4.7 4区医学

Minerva medica Pub Date : 2024-02-01 Epub Date: 2021-06-28 DOI: 10.23736/S0026-4806.21.07609-6

Linjuan Tian, Yunping Wu, Dong Wang, Wei Liu, Yongding Wei, Zhihe Zhou, Dongyue Zhang

引用次数: 0

Antiandrogen agents in COVID-19: a meta-analysis of randomized trials. COVID-19中的抗雄激素药物：随机试验荟萃分析。

IF 4.7 4区医学

Minerva medica Pub Date : 2024-02-01 Epub Date: 2023-05-19 DOI: 10.23736/S0026-4806.23.08538-5

Yuki Kotani, Giovanni Landoni, Tommaso Scquizzato, Nadia Mohamed, Martina Baiardo Redaelli, Rosaria Sofia, Stefano Fresilli, Alberto Zangrillo, Maria L Azzolini

{"title":"Antiandrogen agents in COVID-19: a meta-analysis of randomized trials.","authors":"Yuki Kotani, Giovanni Landoni, Tommaso Scquizzato, Nadia Mohamed, Martina Baiardo Redaelli, Rosaria Sofia, Stefano Fresilli, Alberto Zangrillo, Maria L Azzolini","doi":"10.23736/S0026-4806.23.08538-5","DOIUrl":"10.23736/S0026-4806.23.08538-5","url":null,"abstract":"Introduction: Antiandrogen therapy can reduce the expression of transmembrane protease 2, which is essential for severe acute respiratory syndrome coronavirus-2 to enter the host cells. Prior trials suggested the efficacy of antiandrogen agents in patients with COVID-19. We investigated whether antiandrogen agents reduce mortality compared to placebo or usual care.Evidence acquisition: We searched for randomized controlled trials comparing antiandrogen agents with placebo or usual care alone in adults with COVID-19 in PubMed, EMBASE, the Cochrane Library, the reference lists of retrieved articles, and publications by manufacturers of antiandrogen agents. The primary outcome was mortality at the longest follow-up available. The secondary outcomes included clinical worsening, the need for invasive mechanical ventilation, admission to the intensive care unit, hospitalization, and thrombotic events. We registered this systematic review and meta-analysis in PROSPERO International Prospective Register of Systematic Reviews (CRD42022338099).Evidence synthesis: We included 13 randomized controlled trials enrolling 1934 COVID-19 patients. We found that antiandrogen agents reduced mortality at the longest follow-up available (91/1021 [8.9%] vs. 245/913 [27%]; risk ratio =0.40; 95% confidence interval, 0.25-0.65; P=0.0002; I2=54%). Antiandrogen therapy also reduced clinical worsening (127/1016 [13%] vs. 298/911 [33%]; risk ratio =0.44; 95% confidence interval, 0.27-0.71; P=0.0007; I2=70%) and hospitalization (97/160 [4.4%] vs. 24/165 [15%]; risk ratio =0.24; 95% confidence interval, 0.10-0.58; P=0.002; I2=44%). There was no significant difference in the other outcomes between the two treatment groups.Conclusions: Antiandrogen therapy reduced mortality and clinical worsening in adult patients with COVID-19.","PeriodicalId":18671,"journal":{"name":"Minerva medica","volume":" ","pages":"37-44"},"PeriodicalIF":4.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9480688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0