Minerva cardiology and angiology最新文献_第2页

Trends in coronary artery disease and dyslipidemia-related mortality in the USA from 1999-2020. 1999-2020年美国冠状动脉疾病和血脂异常相关死亡率趋势

IF 1.4 4区医学

Minerva cardiology and angiology Pub Date : 2025-04-11 DOI: 10.23736/S2724-5683.24.06664-X

Muhammad R Cheema, Faizan Ahmed, Farman Ali, Zulfiqar Q Baloch, Abdul M Minhas, Faisal Khosa, Nishant Shah

{"title":"Trends in coronary artery disease and dyslipidemia-related mortality in the USA from 1999-2020.","authors":"Muhammad R Cheema, Faizan Ahmed, Farman Ali, Zulfiqar Q Baloch, Abdul M Minhas, Faisal Khosa, Nishant Shah","doi":"10.23736/S2724-5683.24.06664-X","DOIUrl":"https://doi.org/10.23736/S2724-5683.24.06664-X","url":null,"abstract":"Background: This study examined trends and disparities in USA mortality rates associated with the co-occurrence of coronary artery disease (CAD) and dyslipidemia from 1999-2020.Methods: Data were obtained from the multiple cause of death files using CDC WONDER, spanning 1999-2020. ICD-10 codes (I20-I25 for CAD and E78 for dyslipidemia) identified CAD and dyslipidemia-related deaths in adults aged 25 and older. Statistical analyses examined demographic and regional mortality distributions. Joinpoint regression analysis determined trends in age-adjusted mortality rates (AAMR), estimating annual percentage changes (APC).Results: Between 1999 and 2020, 613,969 CAD and dyslipidemia-related deaths occurred in the USA. The AAMR per 100,000 increased from 6.2 in 1999 to 19.0 in 2020. The AAMR rose sharply from 1999-2005 (APC: 10.2; 95% CI: 9.1, 11.3), increased from 2005-2010 (APC: 3.3; 95% CI: 2.6, 5.0), stabilized through 2010-2016 (APC: 0.8; 95% CI: -0.5, 1.4), and increased again from 2016-2019 (APC: 3.0; 95% CI: 1.7, 4.7). Men accounted for 59.8% of deaths, with an AAMR of 18.2, compared to 8.7 for women. Non-Hispanic (NH) American Indian (13.4) and NH white populations (13.3) had the highest AAMRs, followed by NH black or African American (12), Hispanic or Latino (9.8), and NH Asian or Pacific Islanders (9.1). The Midwest had the highest AAMR (14.1), followed by the West (13.8), South (12.2), and Northeast (11.3). Nonmetropolitan areas had higher AAMRs (14.7) compared to metropolitan areas (12.4).Conclusions: Mortality due to concurrent CAD and dyslipidemia is increasing. Targeted interventions are needed to reduce mortality among vulnerable groups.","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Myocardial deformation analysis in cardiac amyloidosis: a feasible and clinical-oriented evaluation? 心肌淀粉样变的心肌变形分析：一种可行的临床评价方法？

IF 1.4 4区医学

Minerva cardiology and angiology Pub Date : 2025-04-11 DOI: 10.23736/S2724-5683.25.06821-8

Annagrazia Cecere, Martina Perazzolo Marra

引用次数: 0

Serum uric acid and drug-eluting stent implantation for coronary bifurcated lesions. 血清尿酸和药物洗脱支架植入术治疗冠状动脉分叉病变。

IF 1.4 4区医学

Minerva cardiology and angiology Pub Date : 2025-04-11 DOI: 10.23736/S2724-5683.24.06658-4

Hongjie Gao, Dongchao Liu, Zheng Xue, Jingxian Qi, Liang Yin, Bing Duan, Lin Wu, Kun Yang, Bulang Gao, Qinying Cao, Jie Mi

{"title":"Serum uric acid and drug-eluting stent implantation for coronary bifurcated lesions.","authors":"Hongjie Gao, Dongchao Liu, Zheng Xue, Jingxian Qi, Liang Yin, Bing Duan, Lin Wu, Kun Yang, Bulang Gao, Qinying Cao, Jie Mi","doi":"10.23736/S2724-5683.24.06658-4","DOIUrl":"https://doi.org/10.23736/S2724-5683.24.06658-4","url":null,"abstract":"Background: The aim of this study is to investigate the effect of hyperuricemia on prognosis of drug-eluting stent implantation for coronary bifurcated lesions and the value of uric acid levels in predicting the prognosis.Methods: Patients with coronary bifurcation lesions treated with drug-eluting stent implantation were retrospectively enrolled. The clinical, interventional and follow-up data were analyzed.Results: Totally, 308 patients were enrolled and were divided into three groups according to the uric acid levels: group Q1 (N.=105), Q2 (N.=101), and Q3 (N.=102). Before PCI, the stenosis rate was 0.85 (0.80, 0.90) for the main coronary artery and 0.50 (0.50, 0.50) for the branch artery. After PCI and stent deployment, the arterial stenosis rate was 0.20 (0.20, 0.20) for the main coronary artery and 0.50 (0.50, 0.50) for the branch artery. At 36-month follow-up, seven patients died of different reasons, with five patients in group Q1, one in group Q2, and one in group Q3, 96 patients were readmitted for treatment of angina pectoris, with 18 in Q1 group, 29 in Q2 group, and 49 in Q3 group. Twenty-seven patients experienced revascularization because of deterioration of the condition, including six patients in group Q1, seven in group Q2, and 14 in group Q3. After correction of the confounding factors, the readmission rate of angina pectoris was significantly (P<0.001) increased with the increase of the uric acid level: Q3 vs. Q1 (220.47/1000 vs. 66.69/1000 person years, HR 3.65, 95% CI 1.92-6.96) and Q2 vs. Q1 (113.76/1000 vs. 66.69/1000 person years, HR 2.20,95% CI 1.16-4.18).Conclusions: Increased uric acid level is an independent risk factor for cardiogenic readmission rather than for all-cause mortality and revascularization after drug-eluting stent implantation for patients with coronary bifurcation lesions.","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vascular dementia: at the crossroads of brain and heart health. 血管性痴呆：处于大脑和心脏健康的十字路口。

IF 1.4 4区医学

Minerva cardiology and angiology Pub Date : 2025-04-11 DOI: 10.23736/S2724-5683.25.06894-2

Ahmed Sayed, Gerardo Lo Russo

引用次数: 0

Intrinsic and extrinsic determinants of false positive exercise stress echocardiography results in master athletes with suspected coronary artery disease. 怀疑有冠状动脉疾病的运动应激超声心动图假阳性结果的内在和外在决定因素。

IF 1.4 4区医学

Minerva cardiology and angiology Pub Date : 2025-04-11 DOI: 10.23736/S2724-5683.25.06884-X

Andrea Sonaglioni, Michele Lombardo, Carmen Sommese, Claudio Anzà

引用次数: 0

Coronary interventions for circumflex artery: great skills required! 冠状动脉介入治疗：需要高超的技巧！

IF 1.4 4区医学

Minerva cardiology and angiology Pub Date : 2025-04-11 DOI: 10.23736/S2724-5683.25.06867-X

Ivan Ilić, Ana Goločevac

引用次数: 0

Takotsubo Syndrome, a challenging disease: a brief review. Takotsubo综合征，一种具有挑战性的疾病：简要回顾。

IF 1.4 4区医学

Minerva cardiology and angiology Pub Date : 2025-04-11 DOI: 10.23736/S2724-5683.25.06826-7

Giuliana Autiero, Elisabetta Grolla, Arianna Calonaci, Michele Dalla Vestra

{"title":"Takotsubo Syndrome, a challenging disease: a brief review.","authors":"Giuliana Autiero, Elisabetta Grolla, Arianna Calonaci, Michele Dalla Vestra","doi":"10.23736/S2724-5683.25.06826-7","DOIUrl":"https://doi.org/10.23736/S2724-5683.25.06826-7","url":null,"abstract":"Introduction: Takotsubo Syndrome (TTS) is characterized by acute transient left ventricular systolic dysfunction. Despite TTS has been described 30 years ago, its pathogenesis and pathophysiology remain poorly understood and the true prevalence remains uncertain because of its under-recognition.Evidence acquisition: To provide an update on the current understanding of the clinical features of Takotsubo Syndrome, we searched the PubMed databases by using the medical subject headings Takotsubo Syndrome. Exclusion criteria included case reports, conference abstracts, non-English literature and unrelated studies.Evidence synthesis: Patients with TTS classically present with acute-onset chest pain, dyspnea, and changes on the ECG occurring in association with an acute stressful event. This presentation mimicking other causes of acute myocardial injury often represents a clinical dilemma; moreover, the lack of evidence-based interventions to treat the acute episode, to prevent major adverse cardiovascular events and to avoid recurrences represents a difficult challenge for the physicians.Conclusions: At present TTS remains a poorly understood condition with substantial morbidity and mortality and without robust evidence or clinical trials available for the management that need to be addressed. The purpose of this review is to provide an update on the current understanding of the clinical features of this condition, to discuss the latest theories regarding its etiology and pathophysiology, and to highlight the need for future therapeutic interventions.","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic and prognostic significance of serum lncRNA MBNL1-AS1 expression in patients with atherosclerosis. 动脉粥样硬化患者血清 lncRNA MBNL1-AS1 表达的诊断和预后意义。

IF 1.4 4区医学

Minerva cardiology and angiology Pub Date : 2025-04-01 Epub Date: 2024-10-08 DOI: 10.23736/S2724-5683.24.06648-1

Zhao Wang, Liang Cheng, Zhengjie Zhao, Honglei Chen, Junzhi Wang, Jiafeng Niu, Youpei Wang, Xiaoge Zhang

{"title":"Diagnostic and prognostic significance of serum lncRNA MBNL1-AS1 expression in patients with atherosclerosis.","authors":"Zhao Wang, Liang Cheng, Zhengjie Zhao, Honglei Chen, Junzhi Wang, Jiafeng Niu, Youpei Wang, Xiaoge Zhang","doi":"10.23736/S2724-5683.24.06648-1","DOIUrl":"10.23736/S2724-5683.24.06648-1","url":null,"abstract":"Background: Atherosclerosis (AS) is the pathological basis of many cardiovascular and cerebrovascular diseases. To further the investigation of treatments for AS, this research analyzed the role of lncRNA MBNL1-AS1.Methods: MBNL1-AS1 expression in the serum of AS patients and healthy controls were detected by qPCR. Its diagnostic value in AS was assessed by receiver operating characteristic curve (ROC). Additionally, the link between MBNL1-AS1, carotid intima-media thickness (CIMT) and C-reactive protein (CRP) was examined using the Spearman correlation coefficient. The prognostic value of MBNL1-AS1 in AS was assessed using the Kaplan-Meier survival curve and univariate and multivariate Cox regression analysis.Results: The present study consisted of 103 patients with AS and 92 healthy patients (HC) and comparison of baseline data between the two groups revealed no remarkable difference (P>0.05) except for CRP (P<0.0001). The serum of AS patients exhibited a considerably higher expression of MBNL1-AS1 in comparison to the HC group. Furthermore, MBNL1-AS1 was highly expressed in patients following higher CIMT and CRP values, which was positively linked with both, respectively (r>0.5, P<0.001). Meanwhile. MBNL1-AS1 has enhanced diagnostic accuracy in AS patients (AUC=0.893) and can be utilized as an independent prognostic factor for AS. Patients with high MBNL1-AS1 expression have a higher likelihood of cardiovascular events. (log rang P=0.0025).Conclusions: Elevated MBNL1-AS1p can be used as a potential marker for the clinical diagnosis of AS and is linked to a poor prognosis of AS.","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":"129-135"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic value of combined detection of serum neuron-specific enolase and homocysteine in patients with coronary atherosclerosis. 联合检测冠状动脉粥样硬化患者血清神经元特异性烯醇化酶和同型半胱氨酸的诊断价值。

IF 1.4 4区医学

Minerva cardiology and angiology Pub Date : 2025-04-01 Epub Date: 2024-10-08 DOI: 10.23736/S2724-5683.24.06584-0

Fufang Liu, Zhihua Wang, Ling Ren, Junyue Xu

{"title":"Diagnostic value of combined detection of serum neuron-specific enolase and homocysteine in patients with coronary atherosclerosis.","authors":"Fufang Liu, Zhihua Wang, Ling Ren, Junyue Xu","doi":"10.23736/S2724-5683.24.06584-0","DOIUrl":"10.23736/S2724-5683.24.06584-0","url":null,"abstract":"Background: The aim of this paper was to investigate the diagnostic significance and severity assessment of serum neuron-specific enolase (NSE) combined with homocysteine (Hcy) for patients with coronary atherosclerosis (coronary artery disease, CAD).Methods: Two hundred sixty-three patients with coronary artery disease were selected as the research group, and 400 healthy individuals who underwent physical examination during the same period were taken as the control group. Electrochemiluminescence immunoassay and biochemical analyzer were employed to detect the serum NSE and Hcy levels of all subjects. The diagnostic value of combined and individual serum NSE and Hcy detection for the combined group was analyzed using the ROC curve.Results: The serum NSE (19.91±9.98 vs. 11.17±2.35) and Hcy levels (15.76±5.37 vs. 10.17±3.71) in the research group were significantly higher than those in the control group, with a statistically significant difference (P<0.05). The serum NSE (16.67±4.02 vs. 18.63±5.49 vs. 20.29±5.87) and Hcy levels (13.28±2.49 vs. 15.56±2.67 vs. 16.66±3.94) gradually increased across groups A, B, and C, and inter-group comparisons showed statistically significant differences (P<0.05). The AUC value of combined serum NSE and Hcy detection for CAD patients was higher (0.879 vs. 0.724 vs. 0.827) than individual NSE and Hcy testing. The specificity of Hcy for the diagnosis of CAD was the highest, reaching 90.3%. The sensitivity of combined NSE and Hcy (82.9%) was higher than the individual testing sensitivity of the two groups.Conclusions: The combined detection of serum NSE and Hcy has high diagnostic efficacy for CAD and provides reference value in assessing the severity of the disease.","PeriodicalId":18668,"journal":{"name":"Minerva cardiology and angiology","volume":" ","pages":"147-153"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atrial refractoriness, atrial fibrillation, and transcatheter aortic valve implantation: a dangerous trio? 心房难治性、心房颤动和经导管主动脉瓣置入术：危险的三人组？

IF 1.4 4区医学

Minerva cardiology and angiology Pub Date : 2025-04-01 DOI: 10.23736/S2724-5683.24.06778-4

Fortunato Iacovelli, Pierpaolo Caretto, Francesco Loizzi, Zefferino Palamà

引用次数: 0