A. Coulibaly, P. Sombié, R. Hashim, S. Sulaiman, O. Sulaiman, L. Ang, M. Kiendrebeogo, O. Nacoulma
{"title":"GC-MS Analysis and Antibacterial Activities of Feretia apodanthera Del. (Rubiaceae) and Ozoroa insignis Del. (Anacardiaceae)","authors":"A. Coulibaly, P. Sombié, R. Hashim, S. Sulaiman, O. Sulaiman, L. Ang, M. Kiendrebeogo, O. Nacoulma","doi":"10.11648/J.JDMP.20190503.12","DOIUrl":"https://doi.org/10.11648/J.JDMP.20190503.12","url":null,"abstract":"Two medicinal plants, Feretia apodanthera and Ozoroa insignis, used in west African folk medicine to treat infectious diseases, were investigated for their antibacterial potential and their biocidal components. Two extractions were processed in water and aqueous-acetone (70%) and further fractionated by column-chromatography. Both extracts and fractions exhibited selective activity against human pathogenic bacteria as assayed by disc diffusion and microdilution methods. The aqueous-acetone extract of F. apodanthera was active against all the Gram-negative and Gram-positive bacteria (d ≥ 8 mm; MIC ≤ 2.5 mg/ml) while the same extract from O. insignis got markedly activity on Gram-negative bacteria E. coli and K. pneumonia (d ≥ 11 mm). However, the fractions (20µg) of both two plant species were selectively more active on Gram-negative bacteria (d ≥ 11 mm). Tetramethyl silicate, trifluoroamine oxide and neophytadiene were identified by GC-MS as the main volatile compounds present that enhance the antibacterial effects in synergy with others.","PeriodicalId":186601,"journal":{"name":"Journal of Diseases and Medicinal Plants","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123622009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Analysis of Agronomic Characters and Saponins Amount of Ginseng in Four Main Agricultural Areas in Yanbian Prefecture","authors":"Xue Fang, Jinlei Liu, Xiang-guo Li","doi":"10.11648/J.JDMP.20190503.11","DOIUrl":"https://doi.org/10.11648/J.JDMP.20190503.11","url":null,"abstract":"The farmland ginseng cultivation in Yanbian Prefecture is the main direction in the future. This paper investigates and studies the two main cities and counties in Yanbian Prefecture. The results show that there is no significant difference in root weight and root diameter between the two-year-old farmland, the three-year-old rooting heavy Wang-qing experimental site is significantly higher than other experimental sites, and the three-year-rooting-rough-dunning experimental site is significantly higher than the other three experimental sites. Position. The correlation analysis of the two-year-old soil indicators with root traits and total saponin content showed that total saponin content only showed a significant positive correlation with total phosphorus content; available phosphorus showed a significant positive correlation with root weight and root diameter; root diameter had a significant positive correlation with electrical conductivity. The content of total saponins and total phosphorus showed a highly significant positive correlation, and a highly significant positive correlation with total nitrogen; root weight and pH showed a highly significant positive correlation; root diameter and available phosphorus showed a highly significant positive correlation, and nitrate nitrogen showed a significant positive correlation. The total saponins content of ginseng in two-year-old farmland showed a significant negative correlation with root weight and root diameter, while the total saponins content in three-year-old farmland showed a very significant negative correlation with root diameter, but no significant correlation with other traits.","PeriodicalId":186601,"journal":{"name":"Journal of Diseases and Medicinal Plants","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132563722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Documentation of Major Poisonous Plant on Livestock in Ethiopia","authors":"T. Getahun, Wondimu Debash Beze","doi":"10.11648/J.JDMP.20190502.13","DOIUrl":"https://doi.org/10.11648/J.JDMP.20190502.13","url":null,"abstract":"The review was conducted with the objective of documenting potentially poisonous plants in Ethiopia. One of the major causes of economic loss in the livestock industry is Poisonous plants especially in the developing country including Ethiopia. In each year poisonous plant affect 3 to 5 percent of the cattle, sheep, goat, and horses that graze ranges. Major loss caused by these plants result from death of livestock, abortions, photosensitization, decreased production, emaciation, and birth defects and also they have other losses due to increased management costs associated with such things as fencing to prevent access of animals to these plants , altered grazing programs, and loss of forage due to removal of these plants. Livestock mostly exposed to toxic plants in dry and early rainy season when feed is in short supply. In this documentation 71 different plants identified from four different area of the country were collected from different governmental and non-governmental organizations and published papers. A more extensive survey is required to document all poisonous plants in the rangelands and to identify the major toxic principles in the different species possibly pharmacological activity. This documentation review the current knowledge on the identity of plants known to have poisoned livestock and research conducted into these toxic plants.","PeriodicalId":186601,"journal":{"name":"Journal of Diseases and Medicinal Plants","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114336537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Laser Irradiation Induces DNA Polymorphism and Alters Phytochemicals Compositions as well as Growth and Yield of Curcuma longa","authors":"F. El-Sherif, Y. Yap, H. Ibrahim","doi":"10.11648/J.JDMP.20190502.12","DOIUrl":"https://doi.org/10.11648/J.JDMP.20190502.12","url":null,"abstract":"Curcuma longa , commonly known as curcuma or turmeric is a perennial herbaceous plant native to Indian subcontinent and Southeast Asia. Its underground part, referred as rhizome, is used for vegetative propagation and source for remedies for various illnesses. Curcuminoid and volatile oils are the major active components found in turmeric, the yellow power obtained from the ground rhizome. He-Ne laser irradiation has been used as biostimulator device to enhance plant growth. In this study, we have pre-treated the curcuma rhizomes with 5, 10- or 15-min He-Ne laser irradiation. Laser pre-treated and non-treated rhizomes were then cultivated in greenhouse for 8 months. The growth parameters, photosynthetic pigment contents, rhizomes yield were measured. The phytochemical compositions of rhizomes from different treatment groups were measured by gas chromatography mass spectrometry and compared. Effects of laser on DNA polymorphism was assessed by ISSR markers. Our results indicated that laser pre-treatments on rhizomes enhanced curcuma plant height, number of roots and rhizomes, rhizomes diameters, and dried weight of leaves and rhizomes, as well as photosynthetic pigments. The enhancement effects are more prominent in 10 min treatment groups. In addition, laser treatment also alters the phytochemical compositions of ethanol extract from the rhizomes. Interestingly, our study has revealed that laser treatment had resulted in DNA polymorphism as shown from the analysis by ISSR markers.","PeriodicalId":186601,"journal":{"name":"Journal of Diseases and Medicinal Plants","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127423383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Mao, Xiaochun Zhou, Yidao Jiang, L. Wan, Z. Tao
{"title":"Indole-3-Carbinol Inhibits Laryngeal Cancer Growth Through Cell Cycle Arrest","authors":"C. Mao, Xiaochun Zhou, Yidao Jiang, L. Wan, Z. Tao","doi":"10.11648/J.JDMP.20190502.11","DOIUrl":"https://doi.org/10.11648/J.JDMP.20190502.11","url":null,"abstract":"The growth of a variety of tumors are inhibited by indole-3-carbinol (I3C) obviously. But, its role in laryngeal cancer is not clear. The goal of this study was to research the probable roles that laryngeal cancer cell apoptosis and proliferation Hep-2 was influenced by I3C. I3C dose-dependently therapy obviously inhibited Hep-2cell proliferation, and, I3C promoted apoptosis and induced cell morphological changes at 100, 200, 300, 400 μM doses. We discovered that I3C shows anticancer effect through various signal pathways after Hep-2 cells I3C therapy. In Hep-2laryngeal cancer cell line, through decreasing cell cycle-related proteins that include cyclin D1, CDK6, CDK4, and pRb, G1 arrest was induced by I3C. Apart from this, BALB/c nude mice constructed tumor-bearing mouse models. BALB/c nude mice were divided into three groups: treated with I3C, untreated control group and pretreated with I3C. After 8 weeks treatment, the untreated control group developed bigger tumors compared to mice treated or pretreated with I3C, and in the tumors such as cyclin D1, CDK6, CDK4 and pRb cell cycle-related proteins were obviously decreased. Further, the study result showed there was no harmful side effect in the heart, liver and kidney of the I3C-treated nude mice. In conclusion, both in vivo and in vitro I3C inhibited proliferation and induced the Hep-2 cells apoptosis, and showed low toxicity to normal cells. By suppressing the expression of cyclin families and CDK, we deduce that I3C can inhibit the Hep-2 cells growth in vitro. On normal organs and tissues, the I3C had no toxic effects and was safe.","PeriodicalId":186601,"journal":{"name":"Journal of Diseases and Medicinal Plants","volume":"191 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131742470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phytochemical Analysis of Telfaria Occidentals and Ocimum Gratissimum Samples Collected from Gwarimpa Abuja Nigeria","authors":"A. Haruna, Mohammed Mairo, Mariya Akilu","doi":"10.11648/J.JDMP.20190501.13","DOIUrl":"https://doi.org/10.11648/J.JDMP.20190501.13","url":null,"abstract":"This study aims at determining the presence of phytochemical constituents in Telfaria occidentalis and Ocimum gratissimum collected from a location in Abuja, FCT. Standard laboratory procedures were employed to achieve the set objectives. To ascertain the phytochemical components responsible for the ethno medicinal properties, a qualitative and quantitative screening of the extracts of the sampled plants was conducted. Telfaria occidentalis and Ocimum gratissimum leaves were collected from the Kado-Bimko market, Gwarinpa-Abuja in October 2016. Phytochemical screening of the plant materials revealed some differences in the phytochemical constituents of the plants tested but showed the presence of Flavonoids, Alkaloids, Anthraquinones, Saponins, and Tannins. The present data suggest that these extracts could be potential sources phytochemicals that could be of great importance for the treatment of various diseases. It is expected that the important phytochemicals recognised in the study of the medicinal plant sample extracts will be very useful in the curing of various diseases in Nigeria.","PeriodicalId":186601,"journal":{"name":"Journal of Diseases and Medicinal Plants","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115100196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Mao, Xiaochun Zhou, Yidao Jiang, L. Wan, Z. Tao
{"title":"Phenethyl Isothiocyanate Inhibits Nasopharyngeal Carcinoma Cell Growth and Invasion","authors":"C. Mao, Xiaochun Zhou, Yidao Jiang, L. Wan, Z. Tao","doi":"10.11648/J.JDMP.20190501.12","DOIUrl":"https://doi.org/10.11648/J.JDMP.20190501.12","url":null,"abstract":"The dietary compound phenethyl isothiocyanate (PEITC), is an active component of cruciferous vegetables and markedly inhibits the growth of a variety of tumors. However, its role in human nasopharyngeal carcinoma (NPC) is obscure. The aim of the present study was to elucidate the possible mechanisms whereby PEITC exhibited anticancer properties in human nasopharyngeal carcinoma NPC-TW01 cells in vitro. The experiment results exhibited that in a dose- and time-dependent manner treatment of NPC-TW01 cells with PEITC significantly inhibited cell proliferation, promoted apoptosis with concurrent G2/M cell cycle arrest and inhibited cell invasion in a dose-dependent manner. These effects were accompanied by significant alterations in the expression levels of key proteins associated with pro-survival signaling pathways, including PI3K, Akt, ERK, NF-κB, Bcl, Bax, cyclin B, CDK4 and CDK6. Significantly, these effects were not reflected in 16HBE normal human bronchial epithelial cells, indicating a safe range of treatment concentrations between 0 and 10 μM PEITC. In conclusion, PEITC exhibited significant anticancer effects against human nasopharyngeal carcinoma cells in vitro with low toxicological impact on normal bronchial epithelial cells. This was achieved through dysregulation of key proteins involved in the occurrence and development of tumors, and this approach may be applied to the clinical treatment of NPC and in drug screening.","PeriodicalId":186601,"journal":{"name":"Journal of Diseases and Medicinal Plants","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128996951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phyllanthus emblica Linn. (Amla) - A Natural Gift to Humans: An Overview","authors":"Firuz Fatema Pria, M. S. Islam","doi":"10.11648/J.JDMP.20190501.11","DOIUrl":"https://doi.org/10.11648/J.JDMP.20190501.11","url":null,"abstract":"Medicinal plants are the precious gift of nature which plays vital role in healthcare system of developing nation and potent source of medicament to heal various diseases in the world. It plays a vital role to preserve our health. Medicinal plants are believed to be much safer. These days, the use of herbal products has become the foremost option for human all over the world because of curing treatment without any side effect. Ayurveda, the oldest health system in the world, provokes the uses amla to treat a host of diseases and promote positive health. It is a well-known fact that all parts of amla are useful in the treatment of various diseases. Among all, the most important part is fruit. Amla fruit is the richest source of vitamin C. Chemical composition of the amla fruit contains more than 80% of water. It also contains protein, carbohydrates, fiber, amino acids and minerals such as calcium, phosphorus, iron, niacin, carotene, thiamine, riboflavin etc. The chemical constituents present in the plant include tannins, gallic acid, ellagic acid, emblicol, phyllembin, lupeol, essential oil, fixed oil etc. Amla fruit is widely used as diuretic, laxative, liver tonic, antipyretic, hair tonic, ulcer preventive and for common cold, fever as alone or in combination with other plants. Research reports on amla reveals its analgesic, anti-tussive, cardioprotective, cytoprotective, immunomodulatory, chemopreventive, antioxidant, memory enhancing, anticancer, antidiabetic and some others properties. In this article, we review the morphology, distribution, nutritional value, chemical constituents, medicinal uses of amla.","PeriodicalId":186601,"journal":{"name":"Journal of Diseases and Medicinal Plants","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134031772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atikur Rahaman, Syed Ali Azmal, Shiekh M. A. Matin, Md Nazmul Haque, Md. Ruhul Amin, Md. Ahsanul Kabir
{"title":"Effect of Neem and Tamarind Leaves as Anthelmintic in Cattle","authors":"Atikur Rahaman, Syed Ali Azmal, Shiekh M. A. Matin, Md Nazmul Haque, Md. Ruhul Amin, Md. Ahsanul Kabir","doi":"10.11648/j.jdmp.20220801.12","DOIUrl":"https://doi.org/10.11648/j.jdmp.20220801.12","url":null,"abstract":"","PeriodicalId":186601,"journal":{"name":"Journal of Diseases and Medicinal Plants","volume":"197 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114344158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}