M. Mahriani, Rosita Dewi Wulandari, Susantin Fajariyah
{"title":"EFFECT OF PERIWINKLE (CATHARANTHUS ROSEUS) LEAF EXTRACT ON LIVER HISTOLOGY OF MICE (MUS MUSCULUS L) AFTER ASPARTAME INDUCE","authors":"M. Mahriani, Rosita Dewi Wulandari, Susantin Fajariyah","doi":"10.31289/biolink.v8i2.5161","DOIUrl":"https://doi.org/10.31289/biolink.v8i2.5161","url":null,"abstract":"Aspartame is an artificial sweetener in foods and beverages. Continuous use of aspartame will result in oxidative stress in the liver. So we need antioxidants from outside the body such as periwinkle leaves.This study aims to determine the effect of periwinkle leaves (Catharanthus roseus L) on aspartame-induced liver histology. This study used 24 male mice divided into 4 groups, namely negative control (K-) without treatment; Positive control (K +) treatment of aspartame; D1: treatment of aspartame and periwinkle extract doses of 0.42 mg/kg. D2: aspartame and periwinkle extract doses of 0.84 mg/kgbb. Administration of aspartame dose of 0.2 mg /kgbb by intraperitoneal for 14 days followed by gavage administration of periwinkle leaf extract for 12 days. The liver was taken on the 27th day by surgery, then made slide histology with Hematoxylin-Eosin staining. The results show that the administration of Catharanthus roseus leaf extract at a dose of 0.84 mg/kgbw in aspartame-induced mice was effective in reducing hepatocyte damage, namely hydrophilic degeneration and necrosis.","PeriodicalId":186452,"journal":{"name":"BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan)","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127337959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ISOLATION, IDENTIFICATION, AND METAL RESISTANCE TESTING OF SOIL FUNGI (RHIZOSPHERE) FROM BANGKA TIN POST-MINING","authors":"Mutiara Darlingga, Rahmad Lingga, A. Kurniawan","doi":"10.31289/biolink.v8i2.5512","DOIUrl":"https://doi.org/10.31289/biolink.v8i2.5512","url":null,"abstract":"The ecological impacts of tin mining activities in the Bangka island is the presence of heavy metal contamination that accumulated in the environment. One of the heavy metals that was often found in post-tin mining areas is lead (Pb). Mycoremediation is a method that can be used to reduce lead pollution in post-tin mining areas. This study aimedto isolate, resistance test and identify to Pb-resistant soil fungi (rhizosphere) in the post-tin area of Bangka. The research methods included isolation, test of fungal resistance to Pb metal (Control, 150ppm, 250ppm, 350ppm, 500ppm, 1,000ppm, 5,000ppm and 10,000ppm), macroscopic and microscopic identification. The results showed that 9 isolates tested, there were 6 isolates that were resistant to Pb up to the concentration of 5,000 ppm, namely isolates I1(Rhizoctonia), I2(Penicilllium sp1), I5(Papulaspora), I6(Penicillium sp2), I7(Penicillium sp3) and I9 (Sclerotium). Three isolates of soil fungus were not resistant to Pb up to a concentration of 5,000 ppm, namely isolates I4 (Sclerotium), I8(Microsporum), and I10(Cladosporium). All isolates did not grow anymore at a concentration of 10,000 ppm of Pb.","PeriodicalId":186452,"journal":{"name":"BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan)","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125115349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. K. Bakri, Raihanul Akmal, A. Vonna, L. S. Desiyana, Fitrah Sari
{"title":"CORRELATION BETWEEN ADHERENCE OF ANTIHYPERTENSIVE DRUGS USE AND BLOOD PRESSURE CONTROL IN PATIENTS WITH ESRD UNDERGOING HEMODIALYSIS","authors":"T. K. Bakri, Raihanul Akmal, A. Vonna, L. S. Desiyana, Fitrah Sari","doi":"10.31289/biolink.v8i2.6028","DOIUrl":"https://doi.org/10.31289/biolink.v8i2.6028","url":null,"abstract":"Antihypertensive therapy used in patients with End-Stage Renal Disease undergoing hemodialysis is objected to decrease mortality related to ESRD complications. Nonadherence to antihypertensive therapy can lead to uncontrolled blood pressure. This study aims to determine the level of adherence to antihypertensive drugs and its correlation to blood pressure control in ESRD patients undergoing hemodialysis. It was an observational analytic study based on the cross-sectional method. Sixty person subjects were involved using the quota sampling technique. The level of adherence was examined using the Modified Morisky Scale questionnaire. Blood pressure data were obtained from mean values of respectively pre, during, and post-hemodialysis blood pressure within four hemodialysis visitations. The data was examined bivariately using the Chi-square test with a 95% confidence interval. The results show most patients have high level of adherence to antihypertensive treatments (55%) yet have uncontrolled levels of blood pressure (95%). The Chi-square analysis found there is no significant relationship between the level of adherence to antihypertensive therapy and the average blood pressure level of ESRD patients who undergo hemodialysis (p-value 0,301). This finding suggests a consideration in monitoring the effectivity of hypertension management that adherence is not a single significant factor affecting the successfulness of medication.","PeriodicalId":186452,"journal":{"name":"BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan)","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130003081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE REMOVAL EFFICIENCY OF ORGANIC LOADING, PHOSPHATES AND DETERGENTS IN WASTEWATER OF CAR WASH SERVICE BY CONSTRUCTED WETLAND SYSTEM","authors":"Theofilus Stm, H. Sutanto, G. Prihatmo","doi":"10.31289/biolink.v8i2.5796","DOIUrl":"https://doi.org/10.31289/biolink.v8i2.5796","url":null,"abstract":"The car wash wastewater has a proportion of detergent and it can cause considerable impacts to pollute the environment and health if they are not processed in well. SSVF CW is one of an alternative wastewater treatment, because it has the advantage such as wastewater flowing below the surface of the media so it reduces the smell of wastewater. The objective of this study was to determine the removal efficiency of reducing pollutants in the wastewater of treated car wash by Constructed Wetland and the influence of Chrysopogon zizanioides rhizosphere depth in supplying DO distribution. This experimental laboratory scale study used 2 PVC for reactor. Each pipe has 4 sampling points. The DO was measured from different depth, while the other parameters were from the effluent. The ratio of the media used was 1:3:2:4 from the top to the bottom. The SSVF CW system had high TSS removal efficiency of 94.74%, while the removal efficiency of COD, Detergent, and Phosphate was76.21%, 54.54%, 30.65%, respectively. DO distribution at a depth of 84 cm in both pipes increased even though the root zone was only 26.5 cm. ","PeriodicalId":186452,"journal":{"name":"BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123254132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE EFFECTIVENESS TEST OF ALOE VERA EXTRACT INHIBITING THE GROWTH OF STAPHYLOCOCCUS AUREUS BACTERIA","authors":"Nurhidayanti Nurhidayanti","doi":"10.31289/biolink.v8i2.5942","DOIUrl":"https://doi.org/10.31289/biolink.v8i2.5942","url":null,"abstract":"Staphylococcus aureus bacteria are resistant to several kinds of antibiotics, so there is a need for natural antibiotics derived from plants, namely aloe vera. The objective of this study was to determine the effect of aloe vera leaf extract in inhibiting the growth of Staphylococcus aureus bacteria. The type of research used was experimental using the disc diffusion method with a total of 25 samples with five concentrations of 20%, 40%, 60%, 80% and 100% then the data were analyzed using the One Way ANOVA test. The result is that aloe vera extract can inhibit the growth of Staphylococcus aureus bacteria, it is proven by the presence of a disc zone at 100% concentration with a diameter of 11.5 mm. The results of statistical analysis with the One Way ANOVA test, in a value of 0.000, meaning that there was a significant difference. The conclusion obtained is that aloe vera extract can slow down the growth of Staphylococcus aureus bacteria but based on the standard value of sensitivity of an aloe vera extract bacteria with the highest concentration it cannot be used as an antibiotic because it is less than the standard value of 14 mm.","PeriodicalId":186452,"journal":{"name":"BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127778752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE EFFECT OF PASTEURIZATION STAGE ON THE PRODUCTION OF STRAW MUSHROOM (VOLVARIELLA VOLVACEA, BULL. EX. FR./SING.)","authors":"J. Bermuli, Wahyu Irawati, Reisky Megawati Tammu","doi":"10.31289/biolink.v8i2.6167","DOIUrl":"https://doi.org/10.31289/biolink.v8i2.6167","url":null,"abstract":"God created Indonesia with a tropical climate that is very appropriate to support the development of straw mushroom cultivation (Volvariella volvaceae). One of the stages of mushroom cultivation sequentially is pasteurization. This study aims to determine the effect of pasteurization stages, the accuracy of the pasteurization temperature, and the factors that influence the growth of straw mushrooms. The method in this study was carried out using livestock manure, with a composition of 400 gr goat manure and 500 gr rabbit manure. The pasteurization stage is maintained at a temperature of 60-700C with a humidity of 80-90%. The watering interval at the observation stage was 4 days with a frequency of 40% in experiment 1 and every day or a frequency of 100% in experiment 2. The results showed that the pasteurization stage was very influential on the mushroom growing media. Inaccuracy in pasteurization resulted in many weeds that thrived, thus inhibiting the growth of straw mushrooms. The optimal temperature in the pasteurization stage is 60-900C. The factors that influence the growth of mushroom are the selection of materials as fertilizers for mushroom cultivation, temperature, humidity include interval and frequency of watering, pasteurization process, weeding the contaminants, and time of observation.","PeriodicalId":186452,"journal":{"name":"BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan)","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127349706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ISOLATION AND CHARACTERIZATION OF IAA-PRODUCING RIZOSPHERE BACTERIA FROM RICE PLANTS (ORYZA SATIVA L.) IN KEDUNGPANI URBAN VILLAGE, SEMARANG CITY","authors":"S. Sutrisno","doi":"10.31289/BIOLINK.V8I1.4556","DOIUrl":"https://doi.org/10.31289/BIOLINK.V8I1.4556","url":null,"abstract":"Rhizosphere bacteria live in the soil around plant roots. Various rhizosphere bacteria are able to produce the hormone Indole-3-Acetic Acid (IAA) which stimulates plant growth. This study aims to isolate and characterize IAA-producing rhizosphere bacteria in rice plants in the rice fields of Kedungpani urban village, Semarang city. Bacterial enumeration was carried out using the total plate count (TPC) method. The isolates obtained were characterized by observation of colony and cell morphology, gram staining, endospore staining, catalase test, and sugar fermentation test. The ability to produce the IAA hormone was tested using Salkowski's reagent. The enumeration results showed that the total bacteria in the sample was 2.9 x 105 CFU / g. A total of 10 isolates were obtained and were able to produce the IAA hormone with various concentrations. Isolates KP1, KP2, KP3, KP4, KP5, KP6, KP9, KP13, KP14, and KP15 produced IAA with concentrations of 3.389, 5.111, 3.000, 1.667, 1.944, 5.056, 5.444, 4.500, 5.056, and 10.833 ppm, respectively. The results showed that there were 5 isolates with the highest IAA concentrations, namely KP2, KP6, KP9, KP14, and KP15 which had the potential to be used as biostimulant agents for plants.","PeriodicalId":186452,"journal":{"name":"BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan)","volume":"192 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125721034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE STUDY OF TREE LEVEL IN ANGGOMATE WATERSHED AREA , SOUTHEAST SULAWESI","authors":"Ikbal Ikbal, Aqmal Khaery, F. Fachruddin","doi":"10.31289/BIOLINK.V8I1.4581","DOIUrl":"https://doi.org/10.31289/BIOLINK.V8I1.4581","url":null,"abstract":"Anggomate River has ecological and economic value for the local community. Massive community activities in utilizing land in the Anggomate watershed area for plantation, inhabitation, and sand mining lands can cause the tree vegetation decline, even flood often occurs in Andowia region annually. The research method used was a quantitative method. Sampling was performed through a plot-transect method. The plots were placed on the downstream (Labungga Village river area), middle (Laronaga Village river area), and upstream (Andowia Village river area) regions. The study results showed that there are 35 tree species with the individual number of 64. The highest importance value index was obtained from Ficus benjamina L. at 29.38%, Anthocephalus cadamba (Roxb.) Miq) at 25.64%, and Lansium domesticum Corr. at 16.81%. The dominance index of the tree species in the Anggomate river area was 0.971, which indicates that one of the tree species dominated this area, namely, Anthocephalus cadamba (Roxb.) Miq) (Roxb.) Miq). The diversity index in the Anggomate watershed area includes in high category (H’= 3.402 atau H’ > 3). The distribution index includes in the evenly distribution category due to obtaining closely approaching the value of 1 (E= 0.818).","PeriodicalId":186452,"journal":{"name":"BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan)","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132053215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PROFILE OF PULMONARY AND EXTRA PULMONARY TUBERCULOSIS USE GENEXPER AT THE PIRNGADI HOSPITAL MEDAN","authors":"Eva Sartika Daposang, Fenny Hasanah, Dewi Silaban","doi":"10.31289/BIOLINK.V8I1.4638","DOIUrl":"https://doi.org/10.31289/BIOLINK.V8I1.4638","url":null,"abstract":"Mycobacterium tuberculosis as the bacteria that causes TB disease where the healing process takes a long time, using boredom and drug blockages in TB sufferers. This is one reason germs become resistant to several types of anti-tuberculosis drugs known as TB Multi Drug Resistance (MDR TB). The molecular rapid test (TCM) method using GenExper can quickly determine ATD resistance. This study aims to see the results of TCM examination using GenExper in patients with pulmonary tuberculosis and extra pulmonary tuberculosis at dr. Pirngadi Medan. This study used a cross-sectional method by taking laboratory data from the GenExper examination contained in the medical records of patients diagnosed with tuberculosis at Pirngadi Hospital, Medan. Samples obtained from patients using GenExper from January to December 2018 obtained 354 patients with 68.1% more TB incidence in male patients (241/354) than women by 31.9% (113/354). The patients most affected by TB were elderly people aged 56-65 years with a proportion of 23.7%. The largest population affected by TB is self-employed 30.5% and the highest level of education diagnosed is high school graduates 60.5%. Most patients suffered from pulmonary TB at 86.4%.","PeriodicalId":186452,"journal":{"name":"BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan)","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134181013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yennita Dwi April Liana, Hari Sulistiyowati, A. Siddiq
{"title":"DISTRIBUTION PATTERN OF THE EXOTIC PLANT (SYNEDRELLA NODIFLORA (L) GAERTN) IN THE REHABILITATION ZONE, RESORT OF WONOASRI, MERU BETIRI NATIONAL PARK","authors":"Yennita Dwi April Liana, Hari Sulistiyowati, A. Siddiq","doi":"10.31289/BIOLINK.V8I1.4876","DOIUrl":"https://doi.org/10.31289/BIOLINK.V8I1.4876","url":null,"abstract":"Exotic plants are plants that are intentionally or unintentionally included in an area. Based on the results of the 2020 survey, one of the exotic plants found in the Donglo Block Rehabilitation Zone area of Meru Betiri National Park (MBNP) is cinderella weed (Synedrella nodiflora). The objective of this study is to determine the distribution pattern and area of cover of exotic S. nodiflora plants in the research location. Data were collected using a combination method of systematic plot transects measuring 2 x 2 meters which were placed along the transect with a total of 415 plots. The data recorded were the coordinate position of each individual S. nodiflora and the area of the cover. Analysis of distribution pattern data using the Morisita index and visualized with a spatial distribution map using Geographic Information System (GIS). Coverage area analysis was carried out by calculating the percent cover of S. nodiflora. The results of the analysis of the Morisita index showed the value of Iδ = 7.13, which indicates that the distribution pattern of the plants is clustered. In addition, the presence of this species in the study area was occupied 41.7% or 0.85 ha of the total area of 2.04 ha. It shows that this species still did not dominate the area, so it can be said that this species has not yet become an invasive species category in the research location.","PeriodicalId":186452,"journal":{"name":"BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan)","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134374512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}