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Orthotopic vascularized lymph node transfer in breast cancer-related lymphedema treatment: Functional and life quality outcomes 乳腺癌相关淋巴水肿治疗中的异位血管淋巴结转移:功能和生活质量结果
IF 2.1 3区 医学
Microsurgery Pub Date : 2024-02-01 DOI: 10.1002/micr.31147
Federico Lo Torto MD, PhD, Juste Kaciulyte MD, Filippo Di Meglio MD, Marco Marcasciano MD, PhD, Manfredi Greco MD, Diego Ribuffo MD, PhD
{"title":"Orthotopic vascularized lymph node transfer in breast cancer-related lymphedema treatment: Functional and life quality outcomes","authors":"Federico Lo Torto MD, PhD,&nbsp;Juste Kaciulyte MD,&nbsp;Filippo Di Meglio MD,&nbsp;Marco Marcasciano MD, PhD,&nbsp;Manfredi Greco MD,&nbsp;Diego Ribuffo MD, PhD","doi":"10.1002/micr.31147","DOIUrl":"10.1002/micr.31147","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Breast cancer-related lymphedema (BCRL) is a chronic disease that occurs up to 65% of breast cancer survivors. Traditional treatment is conservative, but new surgeries as lymphaticovenous anastomosis (LVA) and vascularized lymph node transfer (VLNT) are at disposal. This study aims to investigate the orthotopic VLNT efficacy in BCRL. Results in terms of limbs' reduction rates and quality of life improvement are compared with the outcomes reported in Literature.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients and Methods</h3>\u0000 \u0000 <p>During patients' selection, inclusion criteria were monolateral ISL stage II or III BCRL with pathologic lymphoscintigraphy imaging and a minimum of previous 6 months of unsuccessful conservative treatment. Bilateral lymphedema, local recurrence or systemic metastasis, acute infection of the limb and deep venous trombosis were exclusion criteria. Surgery consisted in VLNT from the gastroepiploic region to the axilla with axillary scar dissection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>From August 2019 to December 2021, 25 patients were included. At the preoperative scintigraphy exam, mean lymph transport index (TI) was 30 (range; 22.7–29.3). Nine of them (36%) were ISL stage II and 16 (64%) were stage III. Average follow-up was 13.5 months (range; 12–19 months). VLN flaps' survival rate was 100%. One year after surgery, the mean Circumferential Reduction Rate (CRR) resulted 44.62 (range; 27.4–60.3). Infections' rates presented a statistically significant reduction, from an average of 2.4 (range; 1–4) to 0.2 (range; 0–1) episodes per year. Life quality index measured with the LYMQOL questionnaire showed significant improvement after 1 year, from a mean score of 3.28 (range; 2–5) to 8.12 (range; 7–9).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>When compared with Literature evidence, the results of the current study are in line with both VLN inset ways related to BCRL treatment. An optimal therapeutic choice should consider benefits and drawbacks of each orthotopic and heterotopic VLNT, taking into account surgeon's preference and experience and patients' related factors and expectations.</p>\u0000 </section>\u0000 </div>","PeriodicalId":18600,"journal":{"name":"Microsurgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139657714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Orthotopic forelimb transplantation in a Yucatan minipig model: Anatomic and in vivo study 尤卡坦小型猪模型的异位前肢移植:解剖和活体研究
IF 2.1 3区 医学
Microsurgery Pub Date : 2024-01-29 DOI: 10.1002/micr.31136
Brian A. Figueroa MD, Carlos X. Ordenana MD, Majid Rezaei DDS, MSc, Sayf A. Said MD, MPH, Vahe Fahradyan MD, Edoardo Dalla Pozza MD, Lynn M. Orfahli MD, Maria Madajka PhD, Varun Kopparthy PhD, Frank Papay MD, Antonio Rampazzo MD, PhD, Bahar Bassiri Gharb MD, PhD
{"title":"Orthotopic forelimb transplantation in a Yucatan minipig model: Anatomic and in vivo study","authors":"Brian A. Figueroa MD,&nbsp;Carlos X. Ordenana MD,&nbsp;Majid Rezaei DDS, MSc,&nbsp;Sayf A. Said MD, MPH,&nbsp;Vahe Fahradyan MD,&nbsp;Edoardo Dalla Pozza MD,&nbsp;Lynn M. Orfahli MD,&nbsp;Maria Madajka PhD,&nbsp;Varun Kopparthy PhD,&nbsp;Frank Papay MD,&nbsp;Antonio Rampazzo MD, PhD,&nbsp;Bahar Bassiri Gharb MD, PhD","doi":"10.1002/micr.31136","DOIUrl":"https://doi.org/10.1002/micr.31136","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Above elbow transplants represent 19% of the upper extremity transplants. Previous large-animal models have been too distal or heterotopic, did not use immunosuppression and had short survival. We hypothesize that an orthotopic forelimb transplant model, under standard immunosuppression, is feasible and can be used to address questions on peri-transplant ischemia reperfusion injury, and post-transplantation vascular, immunologic, infectious, and functional outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and methods</h3>\u0000 \u0000 <p>Four forelimbs were used for anatomical studies. Four mock transplants were performed to establish technique/level of muscle/tendon repairs. Four donor and four recipient female Yucatan minipigs were utilized for in-vivo transplants (endpoint 90-days). Forelimbs were amputated at the midarm and preserved through ex vivo normothermic perfusion (EVNP) utilizing an RBC-based perfusate. Hourly perfusate fluid-dynamics, gases, electrolytes were recorded. Contractility during EVNLP was graded hourly using the Medical Research Council scale. EVNP termination criteria included systolic arterial pressure ≥115 mmHg, compartment pressure ≥30 mmHg (at EVNP endpoint), oxygen saturation reduction of 20%, and weight change ≥2%. Indocyanine green (ICG) angiography was performed after revascularization. Limb rejection was evaluated clinically (rash, edema, temperature), and histologically (BANFF classification) collecting per cause and protocol biopsies (POD 1, 7, 30, 60 and endpoint). Systemic infections were assessed by blood culture and tissue histology. CT scan was used to confirm bone bridging at endpoint.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Animals 2, 4 reached endpoint with grade 0-I rejection. Limbs 1, 3 presented grade III rejection on days 6, 61. CsA troughs averaged 461 ± 189 ng/mL. EVNLP averaged 4.3 ± 0.52 h. Perfusate lactate, PO<sub>2</sub>, and pH were 5.6 ± 0.9 mmol/L, 557 ± 72 mmHg and 7.5 ± 0.1, respectively. Muscle contractions were 4 [1] during EVNLP. Transplants 2, 3, 4 showed bone bridging on CT.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>We present preliminary evidence supporting the feasibility of an orthotopic, mid-humeral forelimb allotransplantation model under standard immunosuppression regimen. Further research should validate the immunological, infectious, and functional outcomes of this model.</p>\u0000 </section>\u0000 </div>","PeriodicalId":18600,"journal":{"name":"Microsurgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/micr.31136","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139655469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single-stage versus two-stage bone flap reconstruction in chronic osteomyelitis: Multicenter outcomes comparison 慢性骨髓炎的单阶段骨瓣重建与两阶段骨瓣重建:多中心结果比较
IF 2.1 3区 医学
Microsurgery Pub Date : 2023-12-27 DOI: 10.1002/micr.31139
Alice Piccato MD, Alessandro Crosio MD, Andrea Antonini MD, Bruno Battiston MD, PhD, Paolo Titolo MD, Pierluigi Tos MD, PhD, Davide Ciclamini MD
{"title":"Single-stage versus two-stage bone flap reconstruction in chronic osteomyelitis: Multicenter outcomes comparison","authors":"Alice Piccato MD,&nbsp;Alessandro Crosio MD,&nbsp;Andrea Antonini MD,&nbsp;Bruno Battiston MD, PhD,&nbsp;Paolo Titolo MD,&nbsp;Pierluigi Tos MD, PhD,&nbsp;Davide Ciclamini MD","doi":"10.1002/micr.31139","DOIUrl":"10.1002/micr.31139","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Chronic osteomyelitis is an invalidating disease, and its severity grows according to the infection's particular features. The Cierny-Maiden criteria classify it according to the anatomical aspects (I to IV) and also by physiological class (A host being in good immune condition and B hosts being locally (L) or systemically (S) compromised). The surgical approach to chronic osteomyelitis involves radical debridement and dead space reconstruction. Two-stage management with delayed reconstruction is the most common surgical management, while one-stage treatment with concomitant reconstruction is a more aggressive approach with less available literature. Which method gives the best results is unclear. The purpose of this study is to compare single and two-stage techniques.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The authors carried out a retrospective multicentric cohort study to compare two primary outcomes (bone union and infection healing) in one versus two-stage reconstructions with vascularized bone flaps in 23 cases of limb osteomyelitis (22 patients, 23 extremities). Thirteen subjects (56.5%) sustained a single-stage treatment consisting of a single surgery of radical debridement, concomitant soft tissue coverage, and bone reconstruction. Ten cases (43.5%) sustained a two-stage approach: radical debridement, simultaneous primary soft tissue closure, and antibiotic PMMA spacers implanted in 7 patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>No statistical differences were observed between one- and two-stage approaches in bone union rate and infection recurrence risk. Even though bone union seems to be higher and faster in the two-stage than in the one-stage group, and all infection relapses occurred in the one-stage group, data did not statistically confirm these differences. Two of the six cases (33.3%) of bone nonunion occurred in compromised hosts (representing only 17.4% of our sample). The B-hosts bone union rate was 50.0%, while it reached 78.9% in A-hosts, but the difference was not statistically significant (<i>p</i> = .5392). Infection recurrence was higher in B-hosts than in A-hosts (<i>p</i> = .0086) and in <i>Pseudomonas aeruginosa</i> sustained infections (<i>p</i> = .0208), but in the latter case, the treatment strategy did not influence the outcome (<i>p</i> = .4000).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Bone union and infection healing rates are comparable between one and two-stage approaches. <i>Pseudomonas aeruginosa</i> infections have a higher risk of infection ","PeriodicalId":18600,"journal":{"name":"Microsurgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/micr.31139","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139040245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comments on “Revolutionizing patient education: ChatGPT outperforms Google in answering patient queries on free flap reconstruction” 关于 "患者教育的革命:ChatGPT 在回答患者关于游离皮瓣重建的询问方面优于谷歌"。
IF 2.1 3区 医学
Microsurgery Pub Date : 2023-12-27 DOI: 10.1002/micr.31140
Amnuay Kleebayoon PhD, Viroj Wiwanitkit MD
{"title":"Comments on “Revolutionizing patient education: ChatGPT outperforms Google in answering patient queries on free flap reconstruction”","authors":"Amnuay Kleebayoon PhD,&nbsp;Viroj Wiwanitkit MD","doi":"10.1002/micr.31140","DOIUrl":"10.1002/micr.31140","url":null,"abstract":"","PeriodicalId":18600,"journal":{"name":"Microsurgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139040244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A long-term follow up of the laparoscopically harvested free omental flap for breast reconstruction 腹腔镜下游离网膜瓣用于乳房再造的长期随访。
IF 2.1 3区 医学
Microsurgery Pub Date : 2023-12-27 DOI: 10.1002/micr.31137
Anouk A. E. Claessens MD, Martijn A. van Onna MD, Sabrina Maaskant MD, PhD, Coralien L. Broekhuysen MD
{"title":"A long-term follow up of the laparoscopically harvested free omental flap for breast reconstruction","authors":"Anouk A. E. Claessens MD,&nbsp;Martijn A. van Onna MD,&nbsp;Sabrina Maaskant MD, PhD,&nbsp;Coralien L. Broekhuysen MD","doi":"10.1002/micr.31137","DOIUrl":"10.1002/micr.31137","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>There are different types of reconstruction after mastectomy and breast-conserving surgery. Autologous reconstructions are nowadays more often preferred over implant-based reconstructions for many reasons. A more natural looking breast with a durable long-term result is one of the advantages. The greater omentum is frequently used in the general field of reconstructive surgery but has not been widely adopted in breast surgery. This report is the first larger series of patients who underwent a breast reconstruction using the laparoscopically harvested omental free flap (LHOFF). The aim of this report is to provide information about indication, surgical technique, short- and long-term complications, and patient satisfaction with aesthetic outcomes and health-related quality of life (HR-QoL).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Patients underwent a breast reconstruction with the LHOFF from 2014 to 2021 in Máxima Medical Center, Veldhoven, the Netherlands. All patients underwent a diagnostic laparoscopy prior to the reconstruction to examine whether the volume of omentum was deemed sufficient. Outcome measures included the Breast-Q for HR-QoL, patient satisfaction, short- and long-term complications, and abdominal complaints related to the transplanted omentum. Surgical data were retrieved retrospectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty-six patients were included in this article. Patients were 40 to 71 years old with a mean BMI of 21.5 (range 17.0–25.0). Mean weight of the omental free flap was 228 g (range 112–395). Four out of 26 cases underwent surgery due to venous congestion. There was one case of flap failure due to venous thrombosis. Mean time of follow-up was 54 months (range 8–179). Secondary corrections include a nipple reconstruction (<i>n</i> = 11), lipofilling (<i>n</i> = 11), a contralateral breast reduction (<i>n</i> = 3) or a breast implant (<i>n</i> = 2). Patients reported improvement in HR-QoL and good satisfaction with aesthetic outcomes. No abdominal complications were reported during the follow-up period.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The LHOFF is an autologous breast reconstruction technique that results in a soft, small breast with natural ptosis and minimal donor site morbidities. Patients report satisfactory aesthetic outcomes and good quality of life. The main limitation of this technique is the limited amount of volume of the omentum and the possible need for secondary corrections. No abdominal complications were reported. In the future, larger prospective studies are required to support implementation of the LHOFF rec","PeriodicalId":18600,"journal":{"name":"Microsurgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139048936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical utility of the modified frailty index in predicting adverse outcomes in patients undergoing lower extremity free flap reconstruction 改良虚弱指数在预测下肢游离皮瓣重建术患者不良预后方面的临床实用性。
IF 2.1 3区 医学
Microsurgery Pub Date : 2023-12-20 DOI: 10.1002/micr.31135
Romina Deldar MD, Samuel S. Huffman BS, John D. Bovill BS, Nisha Gupta MS, Brian N. Truong BS, Zoë K. Haffner BS, Adaah A. Sayyed BS, Kenneth L. Fan MD, Karen K. Evans MD
{"title":"Clinical utility of the modified frailty index in predicting adverse outcomes in patients undergoing lower extremity free flap reconstruction","authors":"Romina Deldar MD,&nbsp;Samuel S. Huffman BS,&nbsp;John D. Bovill BS,&nbsp;Nisha Gupta MS,&nbsp;Brian N. Truong BS,&nbsp;Zoë K. Haffner BS,&nbsp;Adaah A. Sayyed BS,&nbsp;Kenneth L. Fan MD,&nbsp;Karen K. Evans MD","doi":"10.1002/micr.31135","DOIUrl":"10.1002/micr.31135","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Identifying at-risk patients for complications remains challenging in patients with chronic lower extremity (LE) wounds receiving free tissue transfer (FTT) for limb salvage. The modified-5 frailty index (mFI-5) has been utilized to predict postoperative complications, yet it has not been studied in this population. The aim of this study was to determine the utility of the mFI-5 in predicting adverse postoperative outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Patients ≥60 years, who underwent LE FTT reconstruction at a single institution from 2011 to 2022, were retrospectively reviewed. Patient characteristics, mFI-5, and postoperative outcomes were collected. Cohorts were divided by an mFI-5 score of &lt;2 or ≥2.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 115 patients were identified, of which 71.3% (<i>n</i> = 82) were male, 64.3% (<i>n</i> = 74) had a mFI-5 score of ≥2, and 35.7% (<i>n</i> = 41) had a score &lt;2. The average age and body mass index were 67.8 years and 28.7 kg/m<sup>2</sup>, respectively. The higher mFI-5 cohort had lower baseline albumin levels (3.0 vs. 4.0 g/dL, <i>p</i> = .015) and higher hemoglobin A1c levels (7.4 vs. 5.8%, <i>p</i> &lt; .001). The postoperative length of stay was longer in the higher mFI-5 cohort (18 vs. 13.4 days, <i>p</i> = .003). The overall flap success was 96.5% (<i>n</i> = 111), with no difference between cohorts (<i>p</i> = .129). Postoperative complications were comparable between cohorts (<i>p</i> = .294). At a mean follow-up of 19.8 months, eight patients (7.0%) underwent amputation, and 91.3% (<i>n</i> = 105) were ambulatory.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>High microsurgical success rates can be achieved in comorbid patients with high frailty indexes who undergo FTT for limb salvage. A multidisciplinary team approach may effectively mitigate negative outcomes in elderly, frail patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":18600,"journal":{"name":"Microsurgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138830455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Soft tissue reconstruction of the trunk with pedicled perforator and musculocutaneous flaps: A single-center comparative retrospective study 带蒂穿支皮瓣和肌皮瓣重建躯干软组织:一项单中心回顾性比较研究。
IF 2.1 3区 医学
Microsurgery Pub Date : 2023-11-27 DOI: 10.1002/micr.31131
Emanuele Cammarata MD, Francesca Toia MD, PhD, Martina Maltese MD, Matteo Rossi MD, PhD, Massimiliano Tripoli MD, Adriana Cordova MD
{"title":"Soft tissue reconstruction of the trunk with pedicled perforator and musculocutaneous flaps: A single-center comparative retrospective study","authors":"Emanuele Cammarata MD,&nbsp;Francesca Toia MD, PhD,&nbsp;Martina Maltese MD,&nbsp;Matteo Rossi MD, PhD,&nbsp;Massimiliano Tripoli MD,&nbsp;Adriana Cordova MD","doi":"10.1002/micr.31131","DOIUrl":"10.1002/micr.31131","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Soft tissue trunk reconstruction is often challenging. Although free microvascular flaps are a feasible option in case of extensive defects involving deep structures, pedicled flaps represent a good alternative, especially if harvested and dissected with a “microsurgical” approach. The aim of this study is to evaluate the feasibility of trunk reconstruction with the use of pedicled flaps, according to the application of our reconstructive algorithm, and to compare it to other reconstructive methods.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients and Methods</h3>\u0000 \u0000 <p>From January 2017 to December 2021, we retrospectively analyzed patients who underwent soft tissue reconstruction of the trunk with pedicled flaps at the authors' institution. Patient's demographic, clinical and surgical characteristics and postoperative complications were recorded and analyzed by descriptive statistics. A comparative analysis was made between the study group and two other groups who underwent reconstruction of trunk defects with free flaps and skin grafts, respectively, at the authors' institution.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty-seven patients were included in the study. Patients' age ranged between 36 and 82 years (mean: 57.8 years). Twenty-eight patients were male, while 19 patients were female. In 76.6% of patients (36 out of 47), reconstructive procedures were performed to repair defects resulting from cancer resection. Reconstruction of superficial defects was always achieved with perforator flaps (<i>n</i> = 25). In case of full-thickness defects, reconstruction was carried out with musculocutaneous flaps (<i>n</i> = 22); latissimus dorsi and vastus lateralis were the most used flaps for chest and abdominal wall reconstruction, respectively. In our series, we observed only one case of total flap loss requiring re-operation under general anesthesia. Minor complications occurred in 8.5% of cases (4 out of 47 patients). We observed two cases of partial flap necrosis and two cases of wound dehiscence. In the skin grafts group (<i>n</i> = 53), the mean age was 54.5 years (range 39–85) and 56% of patients were male (<i>n</i> = 30). In 66% of cases (<i>n</i> = 30) the defect resulted from oncological resection. The overall complication rate was 18.8% (<i>n</i> = 10). In the free flaps group (<i>n</i> = 10), the mean age was 49.0 years (range 29–77) and 60% of patients (<i>n</i> = 6) were male. In 70% of cases (<i>n</i> = 7) the defect was caused by oncological resection. Complications occurred in two patients (20%).</p>\u0000 \u0000 <p>No statistically significant differences were found in terms of ov","PeriodicalId":18600,"journal":{"name":"Microsurgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/micr.31131","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138445439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the outcomes of split thickness skin graft versus thickness skin graft for closure of the radial forearm free flap donor site: A systematic review 裂片厚皮移植与厚皮移植用于前臂桡骨游离皮瓣供区闭合的效果比较:系统综述。
IF 2.1 3区 医学
Microsurgery Pub Date : 2023-11-22 DOI: 10.1002/micr.31126
Camilo Mosquera DDS, Ashleigh Weyh MD, DMD, MPH, Michael Malik MD, DDS, Rui Fernandes MD, DMD, Anthony Bunnell MD, DMD, Stacey Nedrud MD, DMD
{"title":"Comparison of the outcomes of split thickness skin graft versus thickness skin graft for closure of the radial forearm free flap donor site: A systematic review","authors":"Camilo Mosquera DDS,&nbsp;Ashleigh Weyh MD, DMD, MPH,&nbsp;Michael Malik MD, DDS,&nbsp;Rui Fernandes MD, DMD,&nbsp;Anthony Bunnell MD, DMD,&nbsp;Stacey Nedrud MD, DMD","doi":"10.1002/micr.31126","DOIUrl":"10.1002/micr.31126","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Radial forearm free flap (RFFF) donor site closure is traditionally performed with split thickness skin grafts (STSG), which can be associated with poor aesthetics, wrist stiffness, paresthesia, reduced strength, and tendon exposure. Full thickness skin grafts (FTSG) are potentially beneficial as they provide a more durable coverage, and the skin graft donor site can be closed primarily, which is more aesthetic. The aim of this systematic review is to compare the outcomes of STSG versus FTSG for closure of the RFFF donor site.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic review was performed, following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The primary objective was to answer: do subjects undergoing RFFF harvest, utilizing FTSG to close the RFFF donor site, compared to STSG, achieve superior aesthetics at the RFFF donor site? Included papers compared FTSG and STSG with statistical data. Means were compared with <i>t</i>-test and proportions with Fisher's exact test.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The initial search resulted in 1851 studies. After applying the inclusion/exclusion criteria, the search resulted in eight studies, with 366 total skin grafts, 197 STSG and 169 FTSG. Six studies evaluated aesthetics utilizing a Likert scale, with the scaled average aesthetic score for FTSG being 7.9/10 compared to 6.9/10 for STSG (<i>p</i> &lt; .001). Tendon exposure was measured in five studies, with a rate of 13.1% for STSG versus 10.6% for FTSG (<i>p</i> = .555). No significant difference in function was observed, however, methods to quantify function were heterogeneous.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>FTSG compared to STSG, resulted in statistically significant improved aesthetics, with comparable rates of tendon exposure and function.</p>\u0000 </section>\u0000 </div>","PeriodicalId":18600,"journal":{"name":"Microsurgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138291369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cannabis use and flap reconstruction: A propensity score matched analysis 大麻使用和皮瓣重建:倾向评分匹配分析
IF 2.1 3区 医学
Microsurgery Pub Date : 2023-11-15 DOI: 10.1002/micr.31038
Olachi O. Oleru MD, Nargiz Seyidova MD, MHQS, Davis Mai MD, MPH, Peter J. Taub MD, MS
{"title":"Cannabis use and flap reconstruction: A propensity score matched analysis","authors":"Olachi O. Oleru MD,&nbsp;Nargiz Seyidova MD, MHQS,&nbsp;Davis Mai MD, MPH,&nbsp;Peter J. Taub MD, MS","doi":"10.1002/micr.31038","DOIUrl":"10.1002/micr.31038","url":null,"abstract":"","PeriodicalId":18600,"journal":{"name":"Microsurgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107591692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Technical pearls and pitfalls of the posterior auricular artery free flap in facial reconstruction 耳后动脉游离皮瓣在面部重建中的技术要点与缺陷。
IF 2.1 3区 医学
Microsurgery Pub Date : 2023-11-12 DOI: 10.1002/micr.31132
Pedro Ciudad MD, PhD, Steven Kirschbaum-Rubin MD, Oscar J. Manrique MD, FACS, Hung-Chi Chen MD, PhD
{"title":"Technical pearls and pitfalls of the posterior auricular artery free flap in facial reconstruction","authors":"Pedro Ciudad MD, PhD,&nbsp;Steven Kirschbaum-Rubin MD,&nbsp;Oscar J. Manrique MD, FACS,&nbsp;Hung-Chi Chen MD, PhD","doi":"10.1002/micr.31132","DOIUrl":"10.1002/micr.31132","url":null,"abstract":"","PeriodicalId":18600,"journal":{"name":"Microsurgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2023-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89718828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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