{"title":"Evaluasi SPO Pengujian Produk Jadi Pre-Marketing terhadap Mutu Sediaan COL (Cairan Obat Luar) Tradisional di Salah Satu Industri X","authors":"Komang Tri Farmani, N. K. Warditiani","doi":"10.24843/ijlfs.2022.v12.i02.p01","DOIUrl":"https://doi.org/10.24843/ijlfs.2022.v12.i02.p01","url":null,"abstract":"Introduction: The traditional medicine industry (TMI) is an industry that can produce all types of traditional medicinal preparations including EML (external medicine liquid). In the process of making traditional medicine (TM), TMI is obliged to follow the rules of GMPTM (good manufacturing practices traditional medicines) which aims to ensure the quality of the preparations produced. In the process, an SOP (standard operating procedure) is needed which contains the steps that must be taken to realize the goals and product quality (specifications) that have been determined. Pre-marketing finished product testing is part of the production process, so it also requires an SOP. One of the IOT X that has made CML has been established long time, of course it already has a Finished Products Pre-Marketing EML Preparations Testing SOP. Objective: to evaluate the SOP of Pre-Marketing Finished Product Testing on the quality of COL preparations, based on quality standards finished products which are regulated in BPOM Regulation No. 32 of 2019 concerning the Safety and Quality Requirements for Traditional Medicine and 1996 SNI (Indonesian National Standard), and GMPTM 2021. Methods: literature study and observational description with a qualitative approach in the form of interviews Results: SOP is in accordance with existing EML quality standards, its implementation has also been implemented well (during the production of COL X products never happened not eligible), and there has never been a recall of EML products during the production period. Conclusion: The SOP for testing finished products in the pre-marketing phase has been implemented properly in accordance with applicable regulations.","PeriodicalId":185562,"journal":{"name":"Indonesian Journal of Legal and Forensic Sciences (IJLFS)","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131896772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of the Proximity Between Perpretator and Victims of Sexual Violence in Forensic Patients’ Clinic at Dr. Soeradji Tirtonegoro Hospital, Klaten, Indonesia: A Cross-Sectional Study from 2019-2021","authors":"Niufti Ayu Dewi Mahila","doi":"10.24843/ijlfs.2022.v12.i02.p05","DOIUrl":"https://doi.org/10.24843/ijlfs.2022.v12.i02.p05","url":null,"abstract":"Background: Violence against women and children is a global problem with a serious impact because it causes a decrease in the quality of health both physically and psychologically for victims. Only some reported sexual violence due to fear and negative stigma in society. Klaten is among the highest cases of violence in Central Java from January-March 2021. The purpose of this study is to determine the level and close relationship between perpretrators and victims of sexual violence. Method: A cross-sectional study was conducted using accidental sampling methods from medical record data and Visum et Repertum of sexual violence at Dr. Soeradji Tirtonegoro Hospital, Klaten from January 2019 – December 202. Results: There were 60 cases of sexual violence, the majority aged <18 years amounted to 57 cases (95%), then 18-65 years 3 cases (5%), the majority of victims were women totaling 55 cases (91.66%) and men 5 cases (8.33%). There is no significant correlation between the relationship from perpetrator and the victim on acts of sexual violence, with a very weak correlation strength and the direction of the correlation being in the same direction. Conclusions: Although the results of this study show a weak correlation between the proximity of perpetrators and victims of sexual violence, the risk of sexual violence can occur to anyone regardless of gender and perpetrators can come from anywhere.","PeriodicalId":185562,"journal":{"name":"Indonesian Journal of Legal and Forensic Sciences (IJLFS)","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133001073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sexual Dimorphism of the first Lumbar vertebra in the Malaysian Population.","authors":"Afiana Rohmani","doi":"10.24843/ijlfs.2022.v12.i01.p05","DOIUrl":"https://doi.org/10.24843/ijlfs.2022.v12.i01.p05","url":null,"abstract":"Sex determination is one of the main steps in the identification of human skeletal remains. The vertebrae are weight-bearing structures in the human body that may provide variety of information from an individual. The aim of this study is to assess the sexual dimorphism of the first lumbar (L1) vertebrae using three-dimensional (3D) computed tomography (CT) imaging to develop population-specific equations for sex identification in the Malay population. Thirteen linear measurements of the first lumbar (L1) vertebrae were taken from 50 males and 50 females’ patients in the Radiology Department of Universiti Kebangsaan Malaysia Medical Centre, using images of the Computed Tomography (CT) scan. Independent T-test and discriminant function analysis (DFA) were performed for analysis. By using independent T-test analysis, there were eight measurements showed statistically significant difference between men and women (p<0.001). Using stepwise method of discriminant analysis showed three measurements predicted sex with the accuracy 93.0% : (a) lower end-plate width (EPWI), (b) lower end-plate depth (EPDI), and posterior height of the vertebral body (VBHp). This study provides discriminant equation for forensic identification of sex from the first lumbar vertebrae among Malaysia population with the accuracy 93.0%.","PeriodicalId":185562,"journal":{"name":"Indonesian Journal of Legal and Forensic Sciences (IJLFS)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124466165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liauw Djai Yen, A. Renate, Evelyn Tena Farrand, Fransisca Theresia, M. Stefani, Sherly Liem, Verdy Dharmawan Thamrin, Veronika Wijaya Ali, Vincentia Melly Putri Lunita
{"title":"Uji Kelalaian Medis: Sebuah Kajian Literatur","authors":"Liauw Djai Yen, A. Renate, Evelyn Tena Farrand, Fransisca Theresia, M. Stefani, Sherly Liem, Verdy Dharmawan Thamrin, Veronika Wijaya Ali, Vincentia Melly Putri Lunita","doi":"10.24843/ijlfs.2022.v12.i01.p02","DOIUrl":"https://doi.org/10.24843/ijlfs.2022.v12.i01.p02","url":null,"abstract":"Medical negligence is a constant issue in medical practice in which its occurrence is constantly increasing, putting patients’ safety at risk. In Indonesia, medical negligence dispute settlement is done by the methods of litigation and non-litigation. However, there is currently no explicit law regarding medical malpractice, medical negligence and medical risk in Indonesia, hence, cases of medical risk are often mistakenly regarded as malpractice. In essence, there are several tests used as benchmarks to regard cases as medical negligence; that includes the Bolam test, Bolitho test and Montgomery test. This literature review aims to present an overview of each test currently used for medical negligence dispute settlement, whereas its application could aid in solving medical disputes in Indonesia.","PeriodicalId":185562,"journal":{"name":"Indonesian Journal of Legal and Forensic Sciences (IJLFS)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127309580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intercanine Distance (ICD) Measurement Using Metric Analysis And Digital Imaging in Bite Mark Gender Identification","authors":"Eko Prastyo","doi":"10.24843/ijlfs.2022.v12.i01.p04","DOIUrl":"https://doi.org/10.24843/ijlfs.2022.v12.i01.p04","url":null,"abstract":"This study aims to determine a gender using Intercanine Distance (ICD) measurement on bite marks with digital imaging and metric analysis. This is a Narrative Literature Review on 11 articles that meet the research requirements, and articles obtained from PubMed, Science Direct, and Wiley databases. It was found that the ICD of men and women measured with metric analysis and digital imaging was significantly different. Therefore, it was suggested that metric analysis is an excellent method to identify gender on bite marks compared to digital imaging, this method is practical, low budget, quick, and accurate.","PeriodicalId":185562,"journal":{"name":"Indonesian Journal of Legal and Forensic Sciences (IJLFS)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134281828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. B. Putra, I. F. Amin, M. Fauzan, Oktavinda Safitry
{"title":"Meluruskan Kesalahpahaman Matematika pada Rasio Casper’s Dictum","authors":"A. B. Putra, I. F. Amin, M. Fauzan, Oktavinda Safitry","doi":"10.24843/ijlfs.2022.v12.i01.p01","DOIUrl":"https://doi.org/10.24843/ijlfs.2022.v12.i01.p01","url":null,"abstract":"Berdasarkan tanatologi, tubuh yang telah mati akan mengalami perubahan. Salah satunya adalah melalui proses penguraian (decomposition). Proses dekomposisi dapat bervariasi antar individu dan antar lingkungan. Terdapat old rule-of-thumb yang menyebutkan pembusukan di udara dua kali lebih cepat daripada di air, dan delapan kali lebih cepat daripada di tanah. Beberapa referensi mencoba menuliskan prinsip tersebut dalam rasio kecepatan pembusukan di tanah:air:udara adalah 1:2:8. Meskipun sama-sama disandarkan pada bunyi Casper’s dictum, terdapat perbedaan perbandingan rasio antara “durasi pembusukan” dan “laju pembusukan”. Oleh karena itu, tinjauan ini dibuat untuk menemukan pernyataan asli dari Casper’s dictum sebagai sumber rujukan rasio dan menjelaskan letak kesalahpahaman rasio perhitungan matematika berdasarkan pernyataan asli tersebut. Dari hasil penelusuran dan analisis didapatkan “durasi pembusukan” memiliki rasio 1:2:8 (udara:air:tanah). Sementara itu, “laju pembusukan” ternyata memiliki rasio yang belum pernah disebutkan dalam berbagai buku teks, yaitu 1:4:8 (tanah:air:udara).","PeriodicalId":185562,"journal":{"name":"Indonesian Journal of Legal and Forensic Sciences (IJLFS)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130412640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pertanggungjawaban Kesalahan Pemberian Obat yang Mengakibatkan Cedera Pada Pasien (Studi Kasus Pn 2258/Pid.Sus/2020/Pn Mdn)","authors":"Immanuel Natanael Tarigan, Anhari Achadi","doi":"10.24843/ijlfs.2022.v12.i01.p06","DOIUrl":"https://doi.org/10.24843/ijlfs.2022.v12.i01.p06","url":null,"abstract":"Pelayanan resep obat di apotek merupakan bentuk pelayanan kefarmasian oleh apoteker. Pelayanan kefarmasian juga dilakukan oleh tenaga teknis kefarmasian (TTK) yang membantu apoteker. Masih ditemukan beberapa kasus kesalahan pemberian obat di apotek. Pada kasus dilaporkan sebuah kesalahan pemberian obat di apotek yang dilakukan oleh tenaga non kefarmasian tanpa pengawasan oleh apoteker dan TTK. Dua orang TTK didakwakan dengan pasal 361 KUHP dengan dakwaan karena kelalaiannya menyebabkan kesakitan pada pasien. Pada analisis ditemukan bahwa kelalaian pemberian obat dilakukan oleh tenaga non kefarmasian tanpa pengawasan. Selain itu, pada apotek pada kasus, juga didapati adanya tanggung jawab yang sama atas pelayanan resep obat pasien oleh semua pegawai, baik TTK atau tenaga non kefarmasian. Analisis kasus dilakukan dengan membandingkan kasus dengan aturan yang berlaku. Berdasarkan peraturan yang berlaku, seorang apoteker dapat dimintakan pertanggung jawabannya atas kelalaian yang dilakukan seseorang yang bekerja di bawahnya dengan dasar vicarious liability. Kedua TTK dinyatakan tidak dapat dibuktikan secara sah dan meyakinkan melakukan tindak pidana sebagaimana didakwakan.”. \u0000Kata kunci: resep; obat; apoteker; apotek; kelalaian \u0000 \u0000Prescription services at pharmacies is a form of pharmacy service by pharmacists. Pharmaceutical services are also carried out by pharmaceutical technical staff who assist pharmacists. There are several cases of errors in drug administration in pharmacies. In this case, it was reported that an error in drug administration at the pharmacy was carried out by a non-pharmaceutical staff without supervision by the pharmacist and pharmaceutical technical staff. Two pharmaceutical technical staffs were charged with Article 361 KUHP regarding negligence that caused harm to the patient. Based on analysis it was found that negligence in administering the drugs was carried out by non-pharmaceutical personnel without supervision. In addition, in this pharmacy, it was also found that both pharmaceutical technical staff or non-pharmaceutical staff were responsible for prescribing the drugs. This case was analized by comparing cases with applicable laws. Based on the law, a pharmacist can be held responsible for the negligence of someone who works under them on the basis of vicarious liability. The two pharmaceutical technical staffs were declared unable to be legally and convincingly proven to have committed a criminal act as charged. \u0000Keywords: recipe; drug; pharmacist; pharmacy; negligence","PeriodicalId":185562,"journal":{"name":"Indonesian Journal of Legal and Forensic Sciences (IJLFS)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114636055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"STUDY OF IMPLEMENTATION OF PHARMACEUTICAL DESTRUCTION IN PHARMACIES IN DENPASAR CITY","authors":"Farah Adilla","doi":"10.24843/ijlfs.2022.v12.i01.p03","DOIUrl":"https://doi.org/10.24843/ijlfs.2022.v12.i01.p03","url":null,"abstract":"Destruction of pharmaceutical preparations is one of pharmaceutical cares in Pharmacy which regulated in Permenkes RI No. 73 of 2016. The aim of this study is to describe the implementation of pharmaceutical care standard about destruction of pharmaceutical preparations in several pharmacies in Denpasar City. This study uses descriptive qualitative research through interviews. Data was collected by survey in 12 pharmacies in Denpasar City with 12 respondents on June 2020. This study uses total sampling technique in which the entire populations are used. Based on the identification results, the destruction of pharmaceutical preparations in majority of pharmacies are not in accordance with applicable regulation.","PeriodicalId":185562,"journal":{"name":"Indonesian Journal of Legal and Forensic Sciences (IJLFS)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115466181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Taufik Suryadi, Muhammad Jundi Ramadhanif, R. Sari, Ayu Wulandari, Farah Kamila
{"title":"IDENTIFIKASI PADA JENAZAH YANG DITEMUKAN DI PINGGIR PANTAI","authors":"Taufik Suryadi, Muhammad Jundi Ramadhanif, R. Sari, Ayu Wulandari, Farah Kamila","doi":"10.24843/ijlfs.2021.v11.i02.p06","DOIUrl":"https://doi.org/10.24843/ijlfs.2021.v11.i02.p06","url":null,"abstract":"Identifikasi merupakan suatu upaya membantu penyidik dalam menentukan identitas serta sebab kematian seseorang. Pada beberapa kasus pemeriksaan identifikasi jenazah dilakukan pada jenazah yang sudah dikuburkan, sehingga pemeriksaan forensik setelah ekshumasi menjadi cara terakhir untuk mendapatkan data terkait identitas dan penyebab kematian korban. Pada artikel ini dilaporkan proses identifikasi sesosok jenazah tanpa identitas dengan anggota tubuh yang tidak lengkap yang ditemukan oleh nelayan di pinggir pantai Pulo Aceh, Propinsi Aceh dalam keadaan telungkup di bawah boat. Jenazah sudah dikuburkan oleh warga, namun setelah terdapat informasi bahwa jenazah kemungkinan warga negara asing, penyidik melakukan prosedur ekshumasi pada jenazah tersebut untuk dilakukan identifikasi. Pada pemeriksaan luar ditemukan jenazah tidak utuh, tanpa kepala, berjenis kelamin laki-laki dengan perkiraan tinggi badan berdasarkan dengan panjang tulang humerus dan radius adalah sekitar 150,83-159,15 cm dan perkiraan tinggi badan dengan menggunakan panjang tulang femur dan tibia adalah sekitar 151,32 – 157,79 cm, usia korban tidak dapat ditentukan. Untuk mendukung proses identifikasi dikirimkan sampel tulang radius dan ulna kiri guna pemeriksaan DNA. Penyebab kematian korban tidak dapat ditentukan karena sudah terjadi adiposera dan perkiraan waktu kematian korban lebih dari satu bulan.","PeriodicalId":185562,"journal":{"name":"Indonesian Journal of Legal and Forensic Sciences (IJLFS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131204153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siti Eliza Hasningsih, Niken Satuti Nur Handayani, P. T. Widodo
{"title":"Determination of Time of Death Based on Blood Ring Formation and RNA Degradation","authors":"Siti Eliza Hasningsih, Niken Satuti Nur Handayani, P. T. Widodo","doi":"10.24843/ijlfs.2021.v11.i02.p03","DOIUrl":"https://doi.org/10.24843/ijlfs.2021.v11.i02.p03","url":null,"abstract":"Time of death (TOD) determination is crucial in criminal cases. The method used to determine the TOD so far is only based on the state of the corpse found, therefore a new method is needed to improve the accuracy of the TOD determination. This study aims to determine the TOD based on a new method, namely the formation of blood rings and RNA degradation. Blood is commonly found in crime scenes. Blood consists of liquid part that is plasma and cellular part consisting of erythrocytes, leukocyte, and thrombocytes. The composition of blood as a liquid that contains dissolved solids makes the drops of dried blood forming “coffee ring effect”, which is a ring-like form on the perimeter of a blood drop. Coffee ring effect is used as an indicator of time by looking at the thickness of the ring formed from the perimeter of the blood drop to the middle which increases with time. RNA degradation was observed using Peptidylprolyl isomerase A (PPIA) gene. The PPIA gene is found in leukocyte and is used to see the degradation of RNA per 30 minutes period using the RT-PCR and qPCR methods. Degradation was observed by comparing the cycle threshold (ct) value of the standard curve with the ct value of the samples per unit time. TOD could be determined by the percentage of the blood ring thickness up until 120th minutes, and by observing the degradation of RNA until the 60th minute, after that the RNA had completely degraded.","PeriodicalId":185562,"journal":{"name":"Indonesian Journal of Legal and Forensic Sciences (IJLFS)","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114596592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}