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HUBUNGAN USIA DAN JUMLAH PARITAS DENGAN TIPE KARSINOMA ENDOMETRIUM DI RSUD PROF. DR. MARGONO SOEKARJO 年龄和公理关系与子宫内膜致癌类型
Medical and Health Science Journal Pub Date : 2023-08-11 DOI: 10.20884/1.mhj.2023.3.1.8741
Arifah Pelangi Nusa, Gita Nawangtantrini, Aditiyono Aditiyono, Dody Novrial, M Yamsum
{"title":"HUBUNGAN USIA DAN JUMLAH PARITAS DENGAN TIPE KARSINOMA ENDOMETRIUM DI RSUD PROF. DR. MARGONO SOEKARJO","authors":"Arifah Pelangi Nusa, Gita Nawangtantrini, Aditiyono Aditiyono, Dody Novrial, M Yamsum","doi":"10.20884/1.mhj.2023.3.1.8741","DOIUrl":"https://doi.org/10.20884/1.mhj.2023.3.1.8741","url":null,"abstract":"Latar Belakang: Kanker endometrium menempati urutan ke-15 dengan jumlah kasus baru terbanyak pada tahun 2020 di dunia. Masih terdapat perbedaan hasil penelitian tentang hubungan usia dan dan jumlah paritas dengan karsinoma endometrium. Tujuan: Untuk mengetahui hubungan usia dan jumlah paritas dengan tipe kersinoma endometrium di RSUD Prof. Dr. Margono Soekarjo. Metode: Penelitian ini merupakan penelitian analitik observasional dengan studi cross sectional. Teknik pengambilan sampel menggunakan total sampling. Jumlah subjek dalam penelitian ini sebanyak 129 pasien karsinoma endometrium di RSUD Prof. Dr. Margono Soekarjo pada tahun 2017-2022. Data yang diambil merupakan data sekunder dari rekam medik RSUD Prof. Dr. Margono Soekarjo. Variabel usia dan jumlah paritas merupakan data yang tercantum di dokumen rekam medis. Data dianalisis menggunakan uji statistik chi-square. Hasil: Total sampel yang didapatkan adalah 129 pasien kanker endometrium. Usia paling banyak ditemukan pada usia 51-60 tahun (41,1%) dan paling sedikit pada usia <40 tahun (7,8%). Jumlah paritas paling banyak ditemukan yaitu paritas ≥2 (55,8%) dan yang paling sedikit adalah paritas 1 (15,5%). Hasil uji uji statistik chi-square usia dengan tipe karsinoma endometrium menunjukkan nilai p = 0,159 (p>0,05). Berdasarkan hasil analisis menunjukkan tidak ada hubungan yang bermakna antara usia dengan tipe kanker endometrium. Hasil uji uji statistik chi-square jumlah dengan tipe karsinoma endometrium menunjukkan nilai p = 0,02 (p<0,05). Berdasarkan hasil analisis menunjukkan ada hubungan yang bermakna antara jumlah paritas dengan tipe kanker endometrium. Kesimpulan: Tidak terdapat hubungan yang bermakna antara usia dengan tipe karsinoma endometrium dan terdapat hubungan yang bermakna antara jumlah paritas dengan tipe karsinoma endometrium di RSUD Prof. Dr. Margono Soekarjo.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135492874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medical and Health Science Journal Pub Date : 2023-08-11 DOI: 10.20884/1.mhj.2023.3.1.9424
Thianti Sylviningrum, Ismiralda Oke Putranti, Ferdi Wiweko Ardianto
{"title":"","authors":"Thianti Sylviningrum, Ismiralda Oke Putranti, Ferdi Wiweko Ardianto","doi":"10.20884/1.mhj.2023.3.1.9424","DOIUrl":"https://doi.org/10.20884/1.mhj.2023.3.1.9424","url":null,"abstract":"Background: Herpes zoster (HZ) is a vesicular eruptive disease affecting the skin and peripheral nerves due to the reactivation of the Varicella Zoster Virus (VZV). VZV reactivation can cause neuropathy and vesicular skin lesions distributed according to nerve dermatomes. Rarely encountered neuropathy of the enteric nervous system can take the form of intestinal pseudo-obstruction with clinical features of paralytic ileus. We report a case of HZ with a clinical picture resembling paralytic ileus which, if treated late, will increase the morbidity and mortality of the sufferer.&#x0D; Case Presentation: A 59-year-old man came to the hospital emergency room with complaints of abdominal hardness, wall tension, pain, and inability to fart and defecate followed by plentiful water contents from the abdomen to the right back. Physical examination showed decreased bowel sounds and eruption of vesicular lesions with erythematous skin base distributed dermatomal T8-10 dextra. Blood tests showed elevated monocytes and hyperglycemia, while abdominal radiology showed dilated colon and normal air distribution in the colon. Tzanck's test revealed multinucleated giant cells. The patient was diagnosed with HZ and showed improvement after being given orally acyclovir and gabapentin.&#x0D; Summary: Neuropathy of the enteric nervous system due to VZV infection needs to be considered in the paralytic ileus clinical manifestation accompanied by vesicular skin lesions pathognomonic for HZ","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"203 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135492879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PROFIL STRATEGI BELAJAR SRL KOMPONEN KOGNITIF DALAM MEMPERSIAPKAN UJIAN SOCA SELAMA MASA PEMBELAJARAN TATAP MUKA TERBATAS 在有限的面对面学习时间内准备SOCA考试的学习策略配置
Medical and Health Science Journal Pub Date : 2023-08-11 DOI: 10.20884/1.mhj.2023.3.1.7760
Catharina Widiartini, Arfi Nurul Hidayah, Marsya Bunga Dis Ardansyah
{"title":"PROFIL STRATEGI BELAJAR SRL KOMPONEN KOGNITIF DALAM MEMPERSIAPKAN UJIAN SOCA SELAMA MASA PEMBELAJARAN TATAP MUKA TERBATAS","authors":"Catharina Widiartini, Arfi Nurul Hidayah, Marsya Bunga Dis Ardansyah","doi":"10.20884/1.mhj.2023.3.1.7760","DOIUrl":"https://doi.org/10.20884/1.mhj.2023.3.1.7760","url":null,"abstract":"Latar Belakang: SOCA merupakan metode assessment yang menguji kemampuan berpikir kritis, penalaran klinis, dan komunikasi mahasiswa. Strategi belajar SRL (self-regulated learning) komponen kognitif merupakan komponen krusial yang berguna selama pemrosesan dan penyimpanan informasi dalam proses persiapan SOCA. SRL dipengaruhi oleh faktor presage berupa perubahan lingkungan belajar. Proses pembelajaran mengalami perubahan sejak pandemi COVID-19 yang semula daring penuh menjadi PTMT. Perubahan lingkungan ini berperan penting dalam proses persiapan SOCA, sehingga profil mengenai proses belajar ini penting untuk dijadikan bahan pemantauan dan evaluasi institusi dalam pembuatan kebijakan, serta menjadi bahan evaluasi diri bagi responden.&#x0D; Tujuan: Untuk mengetahui profil strategi belajar SRL komponen komponen kognitif dalam mempersiapkan ujian SOCA pada mahasiswa FK Unsoed Angkatan 2019, 2020, dan 2021 selama masa PTMT.&#x0D; Metode: Penelitian deskriptif observasional kuantitatif ini menggunakan data primer hasil pengisian kuesioner yang berjudul “Strategi Belajar SRL Dalam Masa Pembelajaran Tatap Muka Terbatas” oleh 199 responden mahasiswa Angkatan 2019, 2020, dan 2021”. Hasil analisis univariat disajikan dalam tabel dan diagram distribusi frekuensi berdasarkan sub komponen strategi belajar dan frekuensi penggunaannya.&#x0D; Hasil: Sebagian besar (70.35%) responden ialah wanita dengan rerata usia ialah 19.6 tahun. Mayoritas responden selalu menerapkan strategi belajar rehearsal dan cukup sering menerapkan strategi belajar elaboration, organizing, dan critical thinking. Proporsi jenis frekuensi penerapan terkecil ialah \"tidak pernah”.&#x0D; Kesimpulan: Jenis frekuensi penerapan “jarang/kadang-kadang” dan “tidak pernah” lebih sedikit daripada jenis frekuensi penerapan “selalu” dan “cukup sering”.&#x0D; &#x0D;","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"221 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135492881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medical and Health Science Journal Pub Date : 2023-08-11 DOI: 10.20884/1.mhj.2023.3.1.8891
Aditya Priagung Prakosa, Wienda Cinta Aliyyu, Nada Janardita Rosyadah, Saniyya Nur, Rahma Ika Amalia
{"title":"","authors":"Aditya Priagung Prakosa, Wienda Cinta Aliyyu, Nada Janardita Rosyadah, Saniyya Nur, Rahma Ika Amalia","doi":"10.20884/1.mhj.2023.3.1.8891","DOIUrl":"https://doi.org/10.20884/1.mhj.2023.3.1.8891","url":null,"abstract":"Diabetes mellitus is a chronic non-communicable disease caused by metabolic disorders in the pancreas organ characterized by an increase in blood sugar levels beyond normal. The Southeast Asian region, which includes Indonesia, is ranked 3rd in the world with a prevalence of diabetes mellitus reaching 11.3%. Meanwhile, Indonesia is ranked 7th out of 10 countries with the most diabetes mellitus sufferers, reaching 10.7 people. Diabetes mellitus can manifest into other diseases, one of which is abnormalities in the oral cavity. Common manifestations of diabetes mellitus in the oral cavity include Oral Infection (Candidiasis), Xerostomia, Periodontal Disease, Recurrent Dental Caries, Burning mouth sensation (related to xerostomia), Taste Dysfunction, Oral Mucosa Alteration (Lichen Planus), Poor Oral Wound Healing. This literature review describes the systemic disease of diabetes mellitus, diagnostic investigations and management of oral manifestations of diabetes mellitus. Management of oral manifestations of diabetes mellitus does not only focus on treating diseases in the oral cavity, but it is more important to eliminate etiological factors and avoid predisposing factors.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135492883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bahasa Indonesia 印度尼西亚语
Medical and Health Science Journal Pub Date : 2023-08-10 DOI: 10.20884/1.mhj.2023.3.1.7034
Nahwa Aulia Kartika Sari, Rani Afifah Nur Hestiyani, Nafiisah Nafiisah
{"title":"Bahasa Indonesia","authors":"Nahwa Aulia Kartika Sari, Rani Afifah Nur Hestiyani, Nafiisah Nafiisah","doi":"10.20884/1.mhj.2023.3.1.7034","DOIUrl":"https://doi.org/10.20884/1.mhj.2023.3.1.7034","url":null,"abstract":"Indonesia as a developing country still faces difficulties in dealing with various health problems, one of which is diarrhea, with the highest prevalence of incidence in the age group of children. Children tend to be indifferent to changes in their own body condition. This is the reason why the role of sufficient knowledge and skills are related to maternal diarrhea management, to reduce the high rate of disability and mortality due to diarrhea. Objective in this research is to determine the relationship between maternal knowledge and efforts to treat diarrhea in children in Banyumas District, Banyumas Regency.&#x0D; The Methods of this study is an observational analytic study with a cross-sectional design on an accessible population of mothers from kindergarteners in Banyumas District, Banyumas Regency. Selected respondents were 100 people using the snowball sampling method.&#x0D; The Result are total of mothers with “good” level of knowledge regarding diarrhea are (72%), and mothers with “sufficient” level are (28%). In terms of the level of diarrhea management, as much as (89%) are in the “good” category, and as much as (11%) are in the “lacking” category. The result of the data analysis test with the Fisher Exact Test shows the significance value of p = 0.631. So, the Conclusion of this research is There is no significant relationship between maternal knowledge of diarrhea management in kindergarteners in Banyumas District, Banyumas Regency.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"105 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135597341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychodynamic Overview of Generalized Anxiety Disorder in Young Adults 青少年广泛性焦虑障碍的心理动力学综述
Medical and Health Science Journal Pub Date : 2023-07-14 DOI: 10.33086/mhsj.v7i01.3558
E. Prasetya, Rizky Dwi Lestari, M. Mahyuddin, Ulaa’ Haniifah, O. Atsira
{"title":"Psychodynamic Overview of Generalized Anxiety Disorder in Young Adults","authors":"E. Prasetya, Rizky Dwi Lestari, M. Mahyuddin, Ulaa’ Haniifah, O. Atsira","doi":"10.33086/mhsj.v7i01.3558","DOIUrl":"https://doi.org/10.33086/mhsj.v7i01.3558","url":null,"abstract":"The Diagnostic and Statistical Manual of Mental Disorders (DSM-5) defines an anxiety disorder as an excessive feeling of fear that occurs in a person that interferes with daily activities. Generalized anxiety disorder causes a person to feel anxious about a wide range of situations and issues. Patients often experience anxiety, feelings of fear and constantly on edge, difficulty concentrating, difficulty sleeping, muscle tension, and frequent irritability. Based on data from the Indonesian Ministry of Health in 2007, there were 450 million people who had to live with mental disorders. The prevalence of adult individuals (aged 18 years and over) and the elderly, there were 11.6% who experienced emotional disorders, such as anxiety and depression. This case report discusses a 20-year-old woman with the main complaint of unclear anxiety, not knowing what to worry about, floating between things she worries about is death, fear of having a serious illness, breakup, fear of losing her job as a content creator, and feeling of being blamed that keeps on coming. Management in the form of giving SSRI antidepressants and psychodynamic psychotherapy is done to try to reinterpret feelings of guilt that often arise as a result of fixation in one phase of their growth and development.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"79 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88767137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traumatic Diaphragmatic Rupture with Visceral Herniation: A Case Report 外伤性膈破裂合并内脏疝1例
Medical and Health Science Journal Pub Date : 2023-07-14 DOI: 10.33086/mhsj.v7i01.3653
Widia Trilaksana Kusuma, Wayan Sindhu, Yudha Prasista
{"title":"Traumatic Diaphragmatic Rupture with Visceral Herniation: A Case Report","authors":"Widia Trilaksana Kusuma, Wayan Sindhu, Yudha Prasista","doi":"10.33086/mhsj.v7i01.3653","DOIUrl":"https://doi.org/10.33086/mhsj.v7i01.3653","url":null,"abstract":"Background: The diaphragm is a dome-shaped respiratory muscle located near the lower ribs, the exact location is below the chest. Diaphragmatic rupture is a medical condition caused by blunt or penetrating trauma, which often leads to herniation of the abdominal viscera into the thoracic cavity. \u0000Case: We presented a case in which a 39-year-old man complained of left chest pain and abdominal pain radiated to his back, after involed in a traffic accident. On physical examination, the left chest was left behind when breathing, a dull sound was found on percussion, with diffuse abdominal tenderness. Thoraco Abdomen CT-scan was performed and it concluded that there was a rupture of the left posterior diaphragm with a diameter of 15 cm which caused herniation of the gastric and intestines to the left of thoracic cavity, accompanied by a collapse of the left lung due to blunt trauma. The patient underwent an explore laparotomy with the aim of repairing his diaphragmatic rupture, and splenectomy procedure to remove the affected spleen. \u0000 Conclusion: Surgery is a mandatory action in order to repair the diaphragm. The choice of the approach to be used, either laparotomy or thoracotomy depends on other organ abnormalities, acute or latent cases, stable or unstable condition of the patient and also depends on the experience of the operator.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74450362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Risk Factors Use Personal Protection Equipment and Exposure to Sulphate Content with Irritant Contact Dermatitis in Car Washing Officers in Malang City 马郎市洗车人员刺激性接触性皮炎危险因素、个人防护装备使用及硫酸盐暴露比较
Medical and Health Science Journal Pub Date : 2023-07-14 DOI: 10.33086/mhsj.v7i01.3846
D. Pravitasari, Aliyyudestrina Windya Nerdenaesti, Syahdan Millenia Danurwendra, Anung Putri Illahika
{"title":"Comparison of Risk Factors Use Personal Protection Equipment and Exposure to Sulphate Content with Irritant Contact Dermatitis in Car Washing Officers in Malang City","authors":"D. Pravitasari, Aliyyudestrina Windya Nerdenaesti, Syahdan Millenia Danurwendra, Anung Putri Illahika","doi":"10.33086/mhsj.v7i01.3846","DOIUrl":"https://doi.org/10.33086/mhsj.v7i01.3846","url":null,"abstract":"Background: Irritant contact dermatitis (ICD) is an occupational disease that involves non-immunological inflammatory mechanisms of the skin, resulting from a response to exposure to irritants, physical, or biological. ICD disease often occurs in car wash employees who are exposed to laundry soap containing sulfate. Most of the factors that cause ICD are the length of exposure to chemicals or from the workers themselves such as knowledge, use of personal protective equipment, and personal hygiene. The purpose of this study was to determine the effect of using personal protective equipment (PPE) and exposure to sulfate content of car wash soap on the incidence of ICD in car wash employees in the city of Malang with and without a history of skin disease. \u0000Method: The research method uses an analytic observational research type with a cross sectional design. The samples studied were 84 respondents who were car wash employees in the city of Malang, both those who had a history of skin diseases (39 respondents) and those who did not have a history of skin diseases (45 respondents). Data were analyzed using univariate and bivariate tests with SPSS application. \u0000Results: The results of the chi square test showed that there were significant differences in risk factors (p < 0.05) on the incidence of ICD. \u0000Conclusion: The conclusion of this study is there is an effect of the use of PPE and exposure to sulfate content on the incidence of ICD in car wash employees in the city of Malang with and without a history of skin diseases.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85119142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Literature Review on Mantra Meditation 咒语禅修的文献综述
Medical and Health Science Journal Pub Date : 2023-07-14 DOI: 10.33086/mhsj.v7i01.3456
R. Saini, J. Sorout
{"title":"Literature Review on Mantra Meditation","authors":"R. Saini, J. Sorout","doi":"10.33086/mhsj.v7i01.3456","DOIUrl":"https://doi.org/10.33086/mhsj.v7i01.3456","url":null,"abstract":"Objective: Meditation has gained popularity in modern times as an adjunctive of therapeutic treatment. This study aimed to study meditation and use of mantra meditation in application of health problems.\u0000Materials and methods\u0000After searching literature through electronic databases, with regards to meditation and mantra meditation in accordance with PRISMA method was done.\u0000Conclusion: Meditation does not deal only spiritual aspect but it has various application as complimentary in various health related problems.\u0000 ","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76889358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biochemical Correlation of Sex Hormone Profile with Diabetes Mellitus Type 2 In Indian Men- A Case-Control Study 印度男性性激素水平与2型糖尿病的生化相关性——一项病例对照研究
Medical and Health Science Journal Pub Date : 2023-07-14 DOI: 10.33086/mhsj.v7i01.3532
Sandeep Kumar, J. Jain, A. Jain
{"title":"Biochemical Correlation of Sex Hormone Profile with Diabetes Mellitus Type 2 In Indian Men- A Case-Control Study","authors":"Sandeep Kumar, J. Jain, A. Jain","doi":"10.33086/mhsj.v7i01.3532","DOIUrl":"https://doi.org/10.33086/mhsj.v7i01.3532","url":null,"abstract":"Introduction:  India, the country with the highest prevalence of diabetes, has between 62,4 and 77,2 million diabetics and pre-diabetics.  The purpose of this study was to investigate the biological correlation between sex hormone profile and type 2 diabetes in Indian men. \u0000Methodology:  In this case-control study, total of 181 diabetic cases and 181 healthy controls were enrolled as per WHO norms. Along with clinic-demographical data, fasting blood glucose, Postprandial blood glucose, HBA1c, insulin, lipid profile and Testosterone, LH, FSH were measured and compared. \u0000Results:  A non-significant difference was observed [p=0.7831] between different ages among the study population's case and control groups. The FPG, HbA1c, total cholesterol, LDL, triglycerides were significantly elevated in cases as compared to controls, except HDL and SHBG, showing non-significant differences. The spearman correlation between Testosterone and different parameters, and all the correlations showed a significant negative correlation. However, Testosterone Vs. Testicular Volume (ml) [r=0.2981], Testosterone Vs. HDL cholesterol(mmol/l) [r=0.04884] and Testosterone Vs. Calculated Free Testosterone (mmol/L) [r=0.007494] respectively shows significant positive correlation. \u0000Conclusion:  Type 2 Diabetes male patients had lower testosterone levels. As a biomarker for Type 2 Diabetes, it is possible to measure changes in serum testosterone levels.","PeriodicalId":18554,"journal":{"name":"Medical and Health Science Journal","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86503511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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