MEDICAL SCIENCES JOURNAL最新文献_第6页

COVID- 19: disease, progress, control and their relation with sex COVID- 19:疾病、进展、控制及其与性别的关系

MEDICAL SCIENCES JOURNAL Pub Date : 2022-03-01 DOI: 10.52547/iau.32.1.1

N. Bahador, Niusha Baseri Salehi, Paniz Baseri Salehi, Masoumeh Samimi, Mitra Adib

{"title":"COVID- 19: disease, progress, control and their relation with sex","authors":"N. Bahador, Niusha Baseri Salehi, Paniz Baseri Salehi, Masoumeh Samimi, Mitra Adib","doi":"10.52547/iau.32.1.1","DOIUrl":"https://doi.org/10.52547/iau.32.1.1","url":null,"abstract":"Worldwide epidemic had a specific role on human health and economic;Corona, for example, as a huge pandemic had an expand effect on human health, social relation, economic, politic and environment with severe respiratory disorder and high mortality rate in the world. Due to importance of SARS-Cov-2, the present paper deals with the route of transmission, their relation with sex, prevention and control. Research shows that sex-linked immunological differences as well as sex hormones are effective in responding to infectious diseases. Since COVID- 19 is a critical global treat, therefore, in this article, factors such as restricting populations, appropriate medicine, forestry, population growth control, global ban on wildlife trade and nutrition, which are important factors in the spread of this organism are discussed. Results illustrated thatsex hormones and presence of ACE2 receptors in male are the most important factors for developing the disease. Hence, it is recommended that they take more responsibility for the use of masks, regular hand washing with disinfectants, reducing the use of cigarettes and alcohol, and using foods containing vitamins such as A, C, E, zinc, Selenium and omega-3s and reduced presence in populations can prevent virus transmission.","PeriodicalId":18492,"journal":{"name":"MEDICAL SCIENCES JOURNAL","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83414734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive rehabilitation of attention and working memory in patients with chronic bipolar disorder using RehaCom software 应用RehaCom软件对慢性双相情感障碍患者注意力和工作记忆的认知康复

MEDICAL SCIENCES JOURNAL Pub Date : 2022-03-01 DOI: 10.52547/iau.32.1.75

Atefe Saeb, Peyman Hassani-Abharian, Shahram Zarrabian

{"title":"Cognitive rehabilitation of attention and working memory in patients with chronic bipolar disorder using RehaCom software","authors":"Atefe Saeb, Peyman Hassani-Abharian, Shahram Zarrabian","doi":"10.52547/iau.32.1.75","DOIUrl":"https://doi.org/10.52547/iau.32.1.75","url":null,"abstract":"Background: Chronic bipolar disorder (CBD) impairs cognition, leads to depression, and deteriorates patients’ quality of life. This study assessed the usefulness of RehaCom cognitive rehabilitation software on attention and working memory functions in patients with CBD. Materials and methods: This was a pre-test, post-test, quasi-experimental study. In this study, 50 patients with CBD at Mahan Rehabilitation Center, Tehran, Iran were selected using purposive sampling technique and were randomly divided into the control and intervention group. Both groups were pre-tested using Beck Depression Inventory, SDMT, PASAT, and n-BACK tests. The intervention group received 10 sessions (45 min each) of RehaCom software intervention. The participants in the control group were waiting-list controls. Data analyzed using descriptive statistics and multivariate analysis of covariance. Significance level was set at 0.05. Results: Cognitive rehabilitation by RehaCom software improved attention (F = 13.92, P = 0.006,  = 0.53) and working memory (F = 43.58, P = 0.002,  = 0.77) as compared to the control group. Conclusion: The results showed that cognitive rehabilitation program by RehaCom software can be used to improve attention function and working memory in patients with chronic bipolar disorder. Therefore, in order to use the software to improve cognitive functions, it is suggested that more detailed studies be conducted on a larger number of these types of patients.","PeriodicalId":18492,"journal":{"name":"MEDICAL SCIENCES JOURNAL","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75214555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of compassion-focused therapy on death anxiety and quality of life among women with multiple sclerosis 以同情为中心的治疗对多发性硬化症妇女死亡焦虑和生活质量的影响

MEDICAL SCIENCES JOURNAL Pub Date : 2022-03-01 DOI: 10.52547/iau.32.1.92

H. Aboutalebi, Nafiseh Yazdchi, hadi Smkhani akbarinejhad

{"title":"Effectiveness of compassion-focused therapy on death anxiety and quality of life among women with multiple sclerosis","authors":"H. Aboutalebi, Nafiseh Yazdchi, hadi Smkhani akbarinejhad","doi":"10.52547/iau.32.1.92","DOIUrl":"https://doi.org/10.52547/iau.32.1.92","url":null,"abstract":"Background: Because multiple sclerosis (MS) affects both the body and the mind, in addition to pharmacological and physiological interventions, psychological interventions should be considered in the treatment of these patients. The aim of this study was to determine the effectiveness of compassion-focused therapy on death anxiety and quality of life in women with multiple sclerosis. Materials and methods: This study was a semi-experimental with a pre-test, post-test control group design. This study consisted of all women with MS in Esfahan who were members of the MS Society in 2019. In total, 30 women were selected and randomly divided into two groups by a purposive sampling method. Members of the experimental group received their treatment in eight sessions of 1.5 hours; however, the control group did not receive any treatment. Data were analyzed using ANOVA with repeated measures. Results: In the pre-test, mean and standard deviation of death anxiety score and quality of life were not significantly different in the experimental and control groups (p>0.05). Compassion-focused therapy reduced patients' death anxiety post-test, and increased their quality of life (p<0.001). At the follow-up stage, the effect of this treatment was lasting (p<0.001). Conclusion: Compassion-focused therapy can reduce death anxiety and thus better cope with the disease and increase the quality of life of women with MS.","PeriodicalId":18492,"journal":{"name":"MEDICAL SCIENCES JOURNAL","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74266659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of different strain mice during in vitro fertilization and embryo development in response to superovulation 不同品系小鼠体外受精和胚胎发育对超排卵反应的评价

MEDICAL SCIENCES JOURNAL Pub Date : 2022-03-01 DOI: 10.52547/iau.32.1.53

J. Shakerzadeh, M. Movahedin, A. Eidi, N. Hayati Roodbari, K. Parivar

{"title":"Evaluation of different strain mice during in vitro fertilization and embryo development in response to superovulation","authors":"J. Shakerzadeh, M. Movahedin, A. Eidi, N. Hayati Roodbari, K. Parivar","doi":"10.52547/iau.32.1.53","DOIUrl":"https://doi.org/10.52547/iau.32.1.53","url":null,"abstract":"Background: Mice are the most commonly used animal in reproductive research and following the urgent need for these type of studies and also due to the increased interest in the ethical principle of animal rights, four various inbred and outbred strains of the laboratory mouse were evaluated to select the more efficient one for reproductive research. Materials and methods: 60 female and 16 male of strains (C57, CD1, NMRI, and Balb/c) weighing 25 to 30g and aged 6 to 8 weeks were evaluated under same conditions at different stages of mature oocyte collection, fertilization and in vitro embryo development up to the blastocyst stage. The data were analyzed using a chi-square test, and the selected significance level was p<0.05. Results: Among the four strains, the highest to lowest fetal survival rates were for the CD1, NMRI, Balb /C and C57 mice, respectively and their values were 38.9, 14.4, 9.1 and 3.1%, individually. Conclusion: Considering the results, we conclude that it is not possible to obtain optimal results for some strains due to using same instructions. The results showed that the highest rate of fertilization and embryo development up to the 8-cell stage was observed in the outbred CD1 mice. It seems that this strain is more applicable than others for reproductive research. In addition, we believe that using different medium during fertilization and embryo development as well as laboratory conditions, probably assist in improving the embryo production while minimized the required number of animals and allowed the achievement of the desired result.","PeriodicalId":18492,"journal":{"name":"MEDICAL SCIENCES JOURNAL","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82033344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of serum level of vitamin D in patients with acute myocardial infarction 急性心肌梗死患者血清维生素D水平的评价

MEDICAL SCIENCES JOURNAL Pub Date : 2022-03-01 DOI: 10.52547/iau.32.1.102

Nazanin Baghaipour, M. Mohammadi, Yasamin Khosravani-Nezhad

{"title":"Evaluation of serum level of vitamin D in patients with acute myocardial infarction","authors":"Nazanin Baghaipour, M. Mohammadi, Yasamin Khosravani-Nezhad","doi":"10.52547/iau.32.1.102","DOIUrl":"https://doi.org/10.52547/iau.32.1.102","url":null,"abstract":"Background: Vitamin D deficiency is related to acute myocardial infarction (MI) directly and indirectly. Therefore, this study evaluated serum level of vitamin D in patients with acute MI. Materials and methods: This is a cross-sectional and descriptive study on 84 patients with acute MI in Amiralmomenin hospital since May 2018 to May 2019. The demographic information of patients including risk factors for MI as: age, gender, body mass index, hypertension, hyperlipidemia, diabetes, cigarettes use or drugs abuse, history of cardiovascular diseases, inpatient time, and vitamin D status are gathered as questionnaires. The data was added to SPSS version 25, and the P-value of 0.05 was considered significant. Results: 52.4% of patients were female. All the patients were 36 to 90 years old, and the mean (±standard deviation) age was 67.51±12.90 years old. 25% of the patients had vitamin D deficiency, 23.8% insufficiency, 11.9% severe deficiency, and 51.2% normal value. However, none of the risk factors were related to the vitamin D status significantly. Conclusion: In this study, none of the risk factors were related to vitamin D status in MI patients, yet cohort studies with major samples are required because there are several studies confirm that vitamin D status has an important role in development of acute MI.","PeriodicalId":18492,"journal":{"name":"MEDICAL SCIENCES JOURNAL","volume":"140 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77748662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of rs2274907 polymorphism of omentin gene with type 2 diabetes in Iranian population 伊朗人群中网膜基因rs2274907多态性与2型糖尿病的关系

MEDICAL SCIENCES JOURNAL Pub Date : 2022-03-01 DOI: 10.52547/iau.32.1.44

Arezoo Nazari, M. Mohammadi, Masoumeh Nezhadali Lamfjani, T. Naji

{"title":"Association of rs2274907 polymorphism of omentin gene with type 2 diabetes in Iranian population","authors":"Arezoo Nazari, M. Mohammadi, Masoumeh Nezhadali Lamfjani, T. Naji","doi":"10.52547/iau.32.1.44","DOIUrl":"https://doi.org/10.52547/iau.32.1.44","url":null,"abstract":"Background: Diabetes is one of the most common chronic metabolic diseases in the world that is caused by decreased insulin secretion or insulin resistance and fat accumulation in visceral adipose tissue (IR). Omentin is a protein inferred from adipose tissue that is associated with the rate of diabetes. The aim of this study was to investigate the relationship between rs2274907 polymorphism of amentine-1 gene with diabetes. Materials and methods: This case-control study was conducted on 70 patients with diabetes and 70 healthy individuals as control. FBS, TG, CHOL, HDL, and LDL were measured in the subjects and genotype determination was performed using PCR-RFLP. Results: Age, body mass index, LDL, cholesterol, triglyceride, fasting high sugar and insulin resistance were significantly different between patients and healthy individuals (p<0.05). No significant difference was observed in omentin level in diabetic compared to control patients (p>0.05). Omentin levels in different genotypes rs2274907 were different in healthy subjects, but the difference was not significant. Omentin levels in different genotypes rs2274907 were different in healthy subjects (p<0.05). Genotype regression analysis showed that genotypes in rs2274907 polymorphism were not related to diabetes (p>0.05). Conclusion: This study revealed that there was no significant relationship between rs2274907 genotype and type 2 diabetes.","PeriodicalId":18492,"journal":{"name":"MEDICAL SCIENCES JOURNAL","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85022053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation on cross-linked nanomicrobial cellulose properties as modern wound dressing 交联纳米微生物纤维素作为现代创面敷料性能的研究

MEDICAL SCIENCES JOURNAL Pub Date : 2022-03-01 DOI: 10.52547/iau.32.1.11

Sahar Abbasi Geravand, R. Khajavi, M. Rahimi, Manouchehr Shamsini Ghiyasvand, A. Meftahi

{"title":"Investigation on cross-linked nanomicrobial cellulose properties as modern wound dressing","authors":"Sahar Abbasi Geravand, R. Khajavi, M. Rahimi, Manouchehr Shamsini Ghiyasvand, A. Meftahi","doi":"10.52547/iau.32.1.11","DOIUrl":"https://doi.org/10.52547/iau.32.1.11","url":null,"abstract":"Background: Nanomicrobial cellulose is an important biopolymer with a three-dimensional structure that is produced by some microorganisms and has been widely used in medicine. One of the unique properties of microbial cellulose is its very high water absorption, which can be used to produce modern wound dressings. But after drying, it’s three-dimensional structure collapses and the amount of water reabsorption decreases. Accordingly, the aim of this project was to preserve the three-dimensional structure of nanomicrobial cellulose by networking it and improving the water reabsorption properties of this biopolymer. In addition, the cell viability, proliferation, and cell growth of the modified structure and untreated microbial cellulose were also studied. Materials and methods: In this study, microbial cellulose was produced, purified, and neutralized using stationary culture. The samples were then treated with different concentrations of citric acid/sodium hypophosphite and crosslinked. Finally, the characteristics of treated and raw samples were studied by various tests including ATR-FTIR, MTT, SEM, water absorption and in vitro and in vitro tests. Results: According to the results, it was found that the cross-linking operation prevents the collapse of the structure and not only does not cause toxicity, but in addition to increasing water uptake, it also increases viability, adhesion, and cell proliferation in the modified cellulose. Conclusion: Cross-linked nanomicrobial cellulose has high potential as a modern wound dressing.","PeriodicalId":18492,"journal":{"name":"MEDICAL SCIENCES JOURNAL","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79086020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effects of GW9508 small molecule on oxidative stress enzymes in colorectal cancer and non-cancerous HUVEC cells GW9508小分子对结直肠癌和非癌性HUVEC细胞氧化应激酶的影响

MEDICAL SCIENCES JOURNAL Pub Date : 2022-03-01 DOI: 10.52547/iau.32.1.31

Behnoosh Rafienia, E. Hoveizi, A. Shahriari

{"title":"Effects of GW9508 small molecule on oxidative stress enzymes in colorectal cancer and non-cancerous HUVEC cells","authors":"Behnoosh Rafienia, E. Hoveizi, A. Shahriari","doi":"10.52547/iau.32.1.31","DOIUrl":"https://doi.org/10.52547/iau.32.1.31","url":null,"abstract":"Background: In this study, we aimed to evaluate the effects of GW9508 as an unsaturated fatty acid on inducing oxidative stress in HT-29 cancer cell line and non-cancer HUVEC cells. Materials and methods: The effects of GW9508 on cell viability were determined by performing MTT assay after 1, 3 and 5 days. The anti-oxidant superoxide dismutase (SOD) and catalase enzymes' assay was performed to evaluate the apoptosis. Moreover, inverted microscope and DAPI staining were applied to measure the changes in cell and nucleus morphology. Results: The IC50 dose of GW9508 was 500 μM in both cancer and normal cells. Results of enzymatic activity assay exhibited the increscent of activity of catalase and SOD in treated cells led to promoting apoptosis in cells. The amount of activities of SOD and catalase in HT-29 treated cells that were calculated 1.254 and 0.338 mU/mg respectively, which had a significant increase compared to activities of these two enzymes in control cells (0.85 and 0.206 mU/mg, respectively) (p≤0.05). There was also a significant increase in the activities of SOD and catalase in HUVEC treated cells (1.111 and 0.517 mU/mg) compared to the activities of the two enzymes in the control group, which were calculated 0.755 and 0.184 mU/mg, respectively. Conclusion: GW9508 small molecule induces oxidative stress and ROS production in HT-29 and HUVEC cells, leading to cytotoxicity and thus promoting apoptotic cell death in cancer cells. However, these effects are contingent upon dose and the type of cell lineages.","PeriodicalId":18492,"journal":{"name":"MEDICAL SCIENCES JOURNAL","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79463317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phytosynthesis of silver nanoparticles with the aqueous extract of portulaca oleracea and its antimicrobial and antioxidant effect against gram-positive and gram-negative bacteria 马齿苋水提物合成纳米银及其对革兰氏阳性和革兰氏阴性细菌的抗菌和抗氧化作用

MEDICAL SCIENCES JOURNAL Pub Date : 2022-03-01 DOI: 10.52547/iau.32.1.21

N. Elyasi, S. Nabizadeh, Z. Shafiei

{"title":"Phytosynthesis of silver nanoparticles with the aqueous extract of portulaca oleracea and its antimicrobial and antioxidant effect against gram-positive and gram-negative bacteria","authors":"N. Elyasi, S. Nabizadeh, Z. Shafiei","doi":"10.52547/iau.32.1.21","DOIUrl":"https://doi.org/10.52547/iau.32.1.21","url":null,"abstract":"Background: Due to the importance of investigating nosocomial infections and drug resistance in bacteria causing these infections, the use of herbs can be very helpful in treatment. In the present study, the effect of silver nanoparticles obtained from portulaca oleracea extract on bacteria causing nosocomial infections and effective parameters in the synthesis of these nanoparticles were investigated. Materials and methods: First, an aqueous extract of portulaca oleracea was added to a 1 mM silver nitrate solution. The extract was used as a reducing and stabilizing agent for nanoparticles. The effect of effective parameters for the optimization of silver nanoparticles was evaluated by ultraviolet-visible spectroscopy and transmission electron microscopy. The antioxidant and antibacterial effect of the synthesized nanoparticles was determined by studying the activity of catalase, MIC, MBC, disk, and well method. Results: The results showed the effect of alkaline pH as well as silver salt concentration on the quality of synthesized nanoparticles. Also, the results of the antimicrobial test showed that gram-negative bacteria revealed significant sensitivity to synthetic nanoparticles and Staphylococcus aureus showed the highest resistance to nanoparticles. Antioxidant properties were also observed against gram-negative strains. Conclusion: The results showed that silver nanoparticles synthesized with portulaca oleracea had antibacterial and antioxidant properties. Therefore, photosynthesis of nanoparticles can be a good option for the treatment of infectious diseases caused by gram-negative bacteria.","PeriodicalId":18492,"journal":{"name":"MEDICAL SCIENCES JOURNAL","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75586477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychometrics of the self-efficacy instrument of clean intermittent urinary catheterization in patients with neural bladder admitted to rehabilitation hospitals in Tehran in 2019 2019年德黑兰康复医院清洁间歇导尿患者自我效能仪的心理测量

MEDICAL SCIENCES JOURNAL Pub Date : 2021-12-01 DOI: 10.52547/iau.31.4.450

Afsaneh Mostagim Ahmadabadi, F. Sahbaeiroy, S. Hejazi

{"title":"Psychometrics of the self-efficacy instrument of clean intermittent urinary catheterization in patients with neural bladder admitted to rehabilitation hospitals in Tehran in 2019","authors":"Afsaneh Mostagim Ahmadabadi, F. Sahbaeiroy, S. Hejazi","doi":"10.52547/iau.31.4.450","DOIUrl":"https://doi.org/10.52547/iau.31.4.450","url":null,"abstract":"Background: The incidence of neural bladder is increasing today and these people need catheterization. Intermittent clean urinary catheterization is a low-risk method for the patients. Materials and methods: This was a descriptive methodological and validation research. For content validity, 10 people were selected by purposive method. For face validity, 25 people were chosen by convenience method Aimed at structural validity, gradual method was used from sounding conductors. For the reliability of the questionnaire, 10 people completed the questionnaire. Results: First, a draft was developed and two qualitative and quantitative methods were used for face validity. The effect scores of the items were not less than 1.5. None of the items less than 62% were deleted according to the table. In construct validity, exploratory factor analysis and varimax rotation methods were used and the adequacy of sample size was 0.78 by KMO test, and the results of Bartlett sphericity test were significant (4017/486 p <0.001). 5 items with a share of less than 0.4 were removed and factor analysis was performed again and the number of factors was reduced to four with a variance of 40.136. The results of internal consistency of Cronbach's alpha coefficient of the whole questionnaire with 32 items were equal to 0.862 and 0.859 for women and men respectively. The results of the stability of the verification tools and the result of the ICC test (0.949) showed a good correlation coefficient for each structure. Conclusion: The tools designed in this study are valid and reliable and can be used in various studies.","PeriodicalId":18492,"journal":{"name":"MEDICAL SCIENCES JOURNAL","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89691057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0