Medical Science and Discovery最新文献

{"title":"Holistic Approach In Stroke Patients: A Clinical Trial","authors":"Abdulvahap Kaya, Ali Timucin Atayoglu","doi":"10.36472/msd.v10i10.1064","DOIUrl":"https://doi.org/10.36472/msd.v10i10.1064","url":null,"abstract":"Objective: This study aimed to explore the holistic relationship between personality types, coping attitudes, physical functioning, and cognitive levels in individuals diagnosed with stroke. Material and Methods: The research employed a single-group design and included 25 stroke patients. The participants, comprising 7 females and 12 males with a mean age of 54.211±8.979 years, underwent a comprehensive assessment. Physical function was assessed using the Berg Balance Scale and Timed Up and Go Tests, and cognitive levels were measured with the Montreal Cognitive Assessment Scale, coping strategies were evaluated through the COPE-R Coping Attitudes Evaluation Scale, and personality types were determined using the Enneagram Scale. Results: A significant correlation was identified between the Montreal Cognitive Assessment, Timed Up and Go, and Berg Balance Scales (p<0.05). However, no significant correlation was observed between COPE-R Coping Attitudes and Enneagram scales (p=0.503). Conclusion: This study underscores the interplay between cognitive and physical functioning in stroke survivors, highlighting the potential impact of cognitive levels on physical capabilities. Surprisingly, coping attitudes and personality types did not significantly influence cognitive or physical function.","PeriodicalId":18486,"journal":{"name":"Medical Science and Discovery","volume":"39 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135218426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliometric Study on Geriatric Emergencies: Intellectual Structure, Prominent Themes, and Future-Directing Topics","authors":"Feruza Turan Sönmez, Ayhan Tabur","doi":"10.36472/msd.v10i10.1076","DOIUrl":"https://doi.org/10.36472/msd.v10i10.1076","url":null,"abstract":"Objective: This study aims to identify the intellectual structure, prominent themes, and diseases associated with geriatric emergency care. Additionally, it seeks to establish research questions for future studies. Material and Methods: Co-citation and co-occurrence analyses were conducted for bibliometric evaluations. The Web of Science database was utilized. Diseases mentioned in 939 articles were identified through thematic coding analysis of abstracts and titles. Finally, questions for the future agenda were prepared. Bibliometric analyses were carried out using R-based Bibliometrix software. Results: Co-citation analysis revealed two main themes: \"Adverse Outcomes in Elderly Post-Emergency Service, Delirium Identification, and Multidisciplinary Interventions\" and \"Diagnosis and Management of Cognitive Dysfunction in Elderly Emergency Department Patients.\" Co-occurrence analyses indicate that the literature clusters around key themes such as \"risk and prevalence,\" \"management and epidemiology,\" \"physical performance,\" \"elderly care and outcomes,\" \"elderly and community,\" \"survival and prognosis,\" and \"stroke and related diseases.\" According to the list of diseases, the ten most frequently studied diseases in geriatric emergency articles are, in order, Cancer, Stroke, Dementia, Depression, Delirium, Alzheimer's, Carcinoma, Metabolic Syndrome, Type 2 Diabetes, and Heart Failure. Conclusion: Adopting a comprehensive approach is essential for improving older adults' quality of life and independenceHealthcare providers and decision-makers should take these findings into consideration, as they make significant contributions to the health and independence of the elderly population. Furthermore, questions for future research agendas have been formulated.","PeriodicalId":18486,"journal":{"name":"Medical Science and Discovery","volume":"27 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134973334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dental Anxiety in Children with Epilepsy: The Influence of Parental Anxiety and Medical History","authors":"Merve Abaklı İnci","doi":"10.36472/msd.v10i10.1083","DOIUrl":"https://doi.org/10.36472/msd.v10i10.1083","url":null,"abstract":"Objective: This study aims to investigate the impact of parental anxiety and a history of epilepsy on children's dental anxiety. Materials and Methods: The study involved 84 children aged 4 to 12 who visited the Pedodontics Department at Necmettin Erbakan University. The subjects were divided into two groups: children with no history of epilepsy (Group 1, n = 44) and children with a history of epilepsy (Group 2, n = 40). Before receiving dental treatment, each child was asked to independently complete the Children's Dental Anxiety Screening Scale (CFSS-DS) questionnaire. Parental dental anxiety was assessed using the Turkish version of the Modified Dental Anxiety Scale (MDAS), which categorizes dental anxiety into five levels. Results: There was no statistically significant difference in CFSS-DS total scores between Group 1 and Group 2 (p = 0.103). Pearson Correlation analysis revealed a statistically significant weak positive association between parental anxiety and children's dental anxiety (p = 0.008). Conclusion: This study found a significant and linear correlation between children's dental anxiety and their parents' dental anxiety. However, it could not establish a direct link between a child's medical history of epilepsy and their anxiety.","PeriodicalId":18486,"journal":{"name":"Medical Science and Discovery","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135218038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of The Effects of Dexmedetomidine against Carbontetracloride-Induced Nephrotoxicity via Oxidative Stress and Apoptosis","authors":"Eyup Dil, Levent Tumkaya, Tolga Mercantepe, Zehra Topal Suzan, Kerimali Akyildiz, Adnan Yilmaz","doi":"10.36472/msd.v10i10.1080","DOIUrl":"https://doi.org/10.36472/msd.v10i10.1080","url":null,"abstract":"Objective: The objective of this work is to investigate the histological and biochemical consequences of administering Dexmedetomidine (DEX), an alpha-2 adrenergic receptor agonist with notable sedative qualities as well as antioxidant and anti-inflammatory characteristics, in the context of Carbon tetrachloride (CCl4)-induced kidney injury. Materials and Methods: The experimental design involved the random allocation of 30 Sprague-Dawley rats into three distinct groups. The experimental group designated as Group 1 received a single intraperitoneal administration of 1ml of saline solution containing 0.09% NaCl. Group 2 received an intraperitoneal injection of carbon tetrachloride (CCl4) at a dosage of 2 milliliters per kilogram. Group 3, referred to as the CCl4+Dexmedetomidine group, received a solitary intraperitoneal (i.p.) dosage of 100 µg/kg dexmedetomidine one hour before the intraperitoneal administration of 2mL/kg CCl4. Results: Extensive necrosis and debris accumulation were observed in the tubules, particularly in the proximal tubules, within the CCl4-applied group. An elevation in malondialdehyde (MDA) concentrations and terminal deoxynucleotidyl transferase dUTP nick end labelling (TUNEL) positivity, along with a reduction in glutathione (GSH) levels, was found in the renal tissues of the CCl4 experimental group as compared to the control group. In contrast, the CCl4+DEX group exhibited a reduction in the quantity of necrotic tubular cells, levels of MDA, and TUNEL positive. Additionally, there was an elevation in GSH levels compared to the group treated with CCl4 alone. Conclusions: The administration of dexmedetomidine has been observed to potentially provide a protective effect against renal damage induced by CCl4. This phenomenon could potentially be linked to the modulation of tissue oxidative stress markers and the attenuation of apoptotic rate. The findings of our investigation provide evidence in favour of the utilization of dexmedetomidine as a promising therapeutic drug for mitigating renal injury.","PeriodicalId":18486,"journal":{"name":"Medical Science and Discovery","volume":"44 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare Medico Legal Cases of Pediatric Intensive Care Unit","authors":"Serbülent Kılıç, Arzu Oto","doi":"10.36472/msd.v10i10.1078","DOIUrl":"https://doi.org/10.36472/msd.v10i10.1078","url":null,"abstract":"Objective: While Multiple Life-threatening Conditions (MLCs) admitted to the Pediatric Intensive Care Unit represent a substantial healthcare burden, the risk factors, epidemiological data, and clinical manifestations of these cases have yet to be systematically and comprehensively documented. Material and Methods: This study was conducted in the Pediatric Intensive Care Unit at Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey, between January 1, 2017, and January 1, 2022. The study included 31 males (35.4%) and 17 females (64.6%) with an average age of 4.7 ± 4.1 years. MLCs were classified into nine groups, including Foreign Body Aspiration (FBA), Blunt Trauma (BT), Asphyxia (ASP), Firearm Injury (FI), Sharp and Penetrating Object Injury (SPOI), Electric Injury (EI), Sports-Related Injury (SRI), Animal Bite Injury (ABI), and Home Accident (HA). Results: Foreign Body Aspiration (FBA) was the most prevalent type of MLC in this study (29.1%). The average hospital stay for FBA cases in the general ward was 3 days (range: 1-11 days), and in the Pediatric Intensive Care Unit was 2 days (range: 1-8 days). Blunt Trauma (BT) cases had an average hospital stay of 4 days (range: 1-12 days) in the general ward and 3 days (range: 1-10 days) in the Pediatric Intensive Care Unit. Surgical intervention was required for 29.1% of patients (n=14). The mean cost of treating a case in our study was calculated to be 5744 ₺ (approximately US$308.57). The majority of MLCs were attributed to FBA (n=14, 43%), followed by BT (n=9, 18%), and ASP (n=8, 16%). Conclusion: The predominance of Multiple Life-threatening Conditions (MLCs) in the Pediatric Intensive Care Unit, with Foreign Body Aspiration (FBA) being the most common cause, underscores the need for heightened awareness and prevention efforts. Understanding the risk factors, clinical presentations, and healthcare costs associated with these cases is essential for healthcare professionals and policymakers in their pursuit of reducing the incidence of MLCs.","PeriodicalId":18486,"journal":{"name":"Medical Science and Discovery","volume":"19 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135461504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D Levels and Diabetes Mellitus: A Study on Age, Sex, and Body Mass Index","authors":"Enver Çiftel, Serpil Çiftel, Ramazan Dayanan, Hasan Atlı","doi":"10.36472/msd.v10i10.1073","DOIUrl":"https://doi.org/10.36472/msd.v10i10.1073","url":null,"abstract":"Objective: The correlation between Body Mass Index (BMI) and vitamin D levels has garnered considerable attention in contemporary medical investigations. Vitamin D, an essential fat-soluble micronutrient, significantly influences bone health, immune system functionality, and various other physiological functions. The bioavailability of vitamin D may be affected by adiposity, which might result in possible deficits in persons with elevated body mass indices. The objective of this retrospective study conducted at a single center was to examine the potential relationship between BMI and diabetes mellitus (DM) with vitamin D serum levels in a cohort of 680 individuals, comprising 511 females and 169 males. Methods: The present study utilized a methodology in which medical records from a single facility were comprehensively reviewed to collect relevant information on BMI and blood 25-hydroxyvitamin D [25(OH)D] levels. The participants were classified into four distinct groups based on their BMI categories, which included normal weight, overweight, obese, and morbidly obese. Statistical methods were employed to investigate the relationship between BMI, diabetes mellitus (DM), age, and 25-hydroxyvitamin D (25(OH)D) levels. Furthermore, multivariate regression analysis was conducted to account for potential confounding variables such as age and gender. Results: The study included a sample of 680 individuals, comprising 511 women (75.1%) with an average age of 41 (±12) and 169 men (24.9%) with an average age of 38 (±13). Vitamin D levels in women were found to be 14±7 ng/mL, while in men, the levels measured at 16.6±7 ng/mL. The study identified a statistically significant difference in vitamin D levels between women and men (p<0.001). The study's findings indicate that there was no significant correlation between vitamin D levels and age among all individuals (p=0.258). However, a significant albeit weak correlation was observed between vitamin D levels and BMI (p=0.002, R2=0.0141). The vitamin D levels of the obese group were measured to be 14±7 ng/mL, while the non-obese group had levels of 16±7 ng/mL. Statistical analysis revealed that vitamin D levels in the obese group were significantly lower compared to the non-obese group (p=0.012). When comparing vitamin D levels between individuals with and without diabetes mellitus (DM), it was observed that the mean vitamin D level was 13.8±6.3 ng/mL in the non-DM group and 16.6±7.6 ng/mL in the DM group. Statistical analysis revealed that vitamin D levels were significantly higher in the DM group (p=0.012). Conclusion: Our study's findings suggest a potential connection between low vitamin D levels and obesity, while factors such as diabetes, age, and gender do not seem to significantly impact this association.","PeriodicalId":18486,"journal":{"name":"Medical Science and Discovery","volume":"15 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135511666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid Isolation of Mononuclear Cells with High Yield from Minimal Blood Volumes: A Simplified and Robust Approach for Immunotherapeutic Applications","authors":"Sudhir Bhatia, Gudrun Baersch","doi":"10.36472/msd.v10i10.1062","DOIUrl":"https://doi.org/10.36472/msd.v10i10.1062","url":null,"abstract":"Objective: Currently, mononuclear cell (MNC) isolation is performed using density gradient methods, which are laborious and time-consuming, requiring a minimum of 10 ml of buffy coat or blood. This method is inadequate for isolating MNCs from small volumes, such as 100 µl. Therefore, we aimed to develop a straightforward, rapid, and cost-effective method for isolating MNCs from minute volumes of blood and buffy coat. Material and Methods: We utilized the MNC isolator to isolate MNCs from microvolumes, such as 100 µl and 500 µl of blood and buffy coat, by simple mixing and centrifugation. The isolated cells were cultured, and ligand-specific magnetic beads were employed to isolate CD4 and CD45 specific cells from the cultured cells. Results: In 15 experiments, the MNC isolator successfully isolated MNCs from small volumes of blood and buffy coat. The cell cultures were established and maintained for up to 3 years without contamination, with the cells remaining healthy. Successful isolations of CD4 and CD45 cells using magnetic beads were achieved, and the cells were successfully frozen and thawed. Conclusion: In this study, we have introduced a simple, cost-effective, and robust method for isolating MNCs from small volumes of buffy coat and blood, suitable for immunological applications and magnetic bead cell isolation. This method is user-friendly and can be adopted in cell culture laboratories worldwide, potentially opening new avenues for the development of novel antibodies, isolation of various cell populations using magnetic beads, and obtaining a large number of T-cells for immunotherapy development, such as CAR T-cell therapies. Keywords: mononuclear cell isolation, buffy coat, blood, CD4 positive cells, magnetic beads","PeriodicalId":18486,"journal":{"name":"Medical Science and Discovery","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135823801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protective Effect of Etanercept in Experimentally Generated Acute Kidney Failure","authors":"Mehmet Kara, Mehmet Fatih Sönmez, Hasan Basri Ulusoy","doi":"10.36472/msd.v10i10.1066","DOIUrl":"https://doi.org/10.36472/msd.v10i10.1066","url":null,"abstract":"Objective: Acute renal failure (ARF) is a clinical syndrome that causes a decrease in the glomerular filtration rate and leads to an accumulation of nitrogenous waste products and uremic toxins. This study investigated the protective effect of Etanercept on ARF. Materials and Methods: Experiments were done on Balb-C female mice. Acute renal failure was created with an intraperitoneal folic acid injection. Etanercept was injected with folic acid in doses of 0.7 mg/kg, 3.5 mg/kg, and 7 mg/kg in treatment groups. Blood urea nitrogen levels, creatinine and cystatin-c were measured on the 7th day of the study. The kidneys were examined histologically with hematoxylin-eosin staining and Tunel assay. Results: Etanercept improved kidney morphology damaged by folic acid. The apoptotic index was low, and there was less dilation in the renal tubules in the groups treated with Etanercept. Folic acid increased blood urea nitrogen levels. This increase was decreased gradually with increased doses of Etanercept. There were no differences in creatinine levels in all groups. Conclusion: This study investigated the protective effects of Etanercept in the context of Acute Renal Failure (ARF). The results demonstrated that Etanercept improved kidney morphology damaged by folic acid, reduced the apoptotic index, and gradually decreased elevated blood urea nitrogen levels. Although creatinine levels showed no significant differences among the treatment groups, the findings suggest that Etanercept may hold promise as a potential agent for the treatment of ARF. Further research and clinical studies are warranted to validate its effectiveness and safety in human subjects.","PeriodicalId":18486,"journal":{"name":"Medical Science and Discovery","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136079034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy and importance of Fine Needle Aspiration Cytology in the prediction of malignancy in thyroid nodules","authors":"Hasan Atlı, Ramazan Dayanan","doi":"10.36472/msd.v10i10.1065","DOIUrl":"https://doi.org/10.36472/msd.v10i10.1065","url":null,"abstract":"Objective: Since thyroid nodules have low malignant potential and thyroid cancers progress slowly, early diagnosis is important for a longer life expectancy. Fine needle aspiration (FNA) is a cost-effective method with an easy application, low complication rate and high diagnostic value. The aim of this study is to assess the diagnosis accuracy and prevalence of thyroid cancer by comparing the findings of FNA procedures performed in our center with definitive histopathology results of patients undergoing surgery after FNA and then comparing these results to the literature. Materials and Methods: Cytology reports of 1040 patients who underwent thyroid FNA between January 2021 and October 2022 were retrospectively evaluated. Definitive histopathology results of 146 patients who underwent total or subtotal thyroidectomy were compared with preoperative FNA cytology results. Thyroid cytological results were classified according to the 2017 Bethesda system diagnostic categories. Results: Cases with definitive histopathology results indicating malignancy accounted for 33.3% of non-diagnostic cases, 14.5% of benign, 18.5% of atypia or follicular lesion of undetermined significance (AUS)/FLUS, 33.3% of follicular neoplasm or suspected follicular neoplasm, 75.0% of suspected malignancy and 100% of malignant preoperative FNAC results. For malignant cases, FNA had a sensitivity of 47.5%, specificity of 98.1%, false-positive rate of 20.8%, false-negative rate of 17.2%, positive predictive value of 79.1%, negative predictive value of 82.8% and accuracy rate of 72.8%. Conclusion: In this study, the prevalence of thyroid cancer exceeded the cancer rates predicted by the 2017 Bethesda classification. Thyroid cancer may be predicted by the follow-up of patients with solitary or multiple nodules without a surgical indication, and a repeat FNA when necessary.","PeriodicalId":18486,"journal":{"name":"Medical Science and Discovery","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136079742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Turkish validity and reliability study of the Infection Prevention Behavior Scale of Individuals (IPBS-I)","authors":"Sibel Tunç Karaman, Gamze Keskin","doi":"10.36472/msd.v10i10.1057","DOIUrl":"https://doi.org/10.36472/msd.v10i10.1057","url":null,"abstract":"Objective: This study aimed to evaluate the validity and reliability of the Infection Prevention Behavior Scale of Individuals (IPBS-I) among Turkish individuals. Materials and Methods: This was a methodological validity and reliability study. A total of 309 individuals between the ages of 18-65 who met the inclusion criteria were enrolled. The IPBS-I was translated into Turkish using the translation-back-translation technique. Data were collected via the Personal Information Form (PIF), Turkish version of the IPBS-I (IPBS-I-TR), and Protective Behaviors Towards COVID-19 Scale (PBCS). Two weeks later, IPBS-I-TR evaluation was repeated. Confirmatory Factor Analysis (CFA) was performed for construct validity, and the PBCS was applied for criterion validity. Its reliability was evaluated using internal consistency, item analysis, and test-retest reliability. Statistical significance was set at p< 0.05. Results: In total, 309 individuals (183 women and 126 men) were enrolled in the study. The mean IPBS-I-TR was 4.09±0.64. The CFA results revealed ᵡ2=167.12, SD=51, and p=0.0001. It was determined that x²/SD was 3.277 in the model and that the model was compatible. The Standardized Root Mean Square Residual (S-RMR)=0.051, Comparative Fit Index (CFI)=0.929, Goodness of Fit Index (GFI)=0.917, and Root Mean Square Error of Approximation (RMSEA)=0.086 were determined to be within the acceptable range. The CFA supported the three-factor structure of the scale. The correlation coefficient with the PBCS was 0.639, confirming the criterion validity of the scale. The Cronbach's alpha coefficients of the entire scale and three subscales (“Blocking the Pathogen,” “Blocking Transmission,” and “Improving Immunity”) were 0.832, 0.826, and 0.725, respectively. The test-retest reliability of the entire scale and the three subscales was excellent (>0.80). Conclusion: The Turkish version of the IPBS-I was confirmed to have good reliability and validity for evaluating infection-prevention behaviors in Turkish society.","PeriodicalId":18486,"journal":{"name":"Medical Science and Discovery","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135968172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}