Medical Research Journal最新文献_第9页

Differences in symptoms and utility of MEWS score in geriatric patients with COVID-19 老年COVID-19患者MEWS评分的症状和效用差异

Medical Research Journal Pub Date : 2022-12-14 DOI: 10.5603/mrj.a2022.0052

Julia Gólska, Krzysztof Białkowski, T. Kłosiewicz

引用次数: 0

Nutritional and functional status as indices of short- and long-term prognosis in patients undergoing surgery due to colorectal cancer 营养和功能状况作为结直肠癌手术患者短期和长期预后的指标

Medical Research Journal Pub Date : 2022-12-14 DOI: 10.5603/mrj.a2022.0054

B. Szukay, K. Tojek, G. Kowalczyk, N. Mysiak, J. Budzyński

引用次数: 0

Percutaneous closure of the iatrogenic atrial septal defect following the transcatheter edge-to-edge mitral valve repair with MitraClip system led to instant improvement of hypoxemia — case report 经导管二尖瓣边缘到边缘修复术后经皮封闭医源性房间隔缺损可立即改善低氧血症-病例报告

Medical Research Journal Pub Date : 2022-12-14 DOI: 10.5603/mrj.a2022.0053

Jakub Ratajczak, A. Sukiennik, M. Woźnicki, J. Kubica

引用次数: 0

Synergistic effect of oxymatrine and 5-fluorouracil on the migratory potential in A549 non-small cell lung cancer cells 氧化苦参碱和5-氟尿嘧啶对A549非小细胞肺癌细胞迁移潜能的协同作用

Medical Research Journal Pub Date : 2022-11-29 DOI: 10.5603/mrj.a2022.0050

Agnieszka Mlicka, Wioletta Zielińska, Klaudia Mikołajczyk, Marta Hałas-Wiśniewska, M. Izdebska, A. Grzanka

引用次数: 0

Depressive and anxiety disorders in the cardiological conditions: psychological interventions 心脏病中的抑郁和焦虑障碍:心理干预

Medical Research Journal Pub Date : 2022-11-29 DOI: 10.5603/mrj.a2022.0051

R. Szczepanowski, M. Wójta-Kempa, A. Pawlak, Jolanta Kolasa, Izabella Uchmanowicz, M. Czapla, Tomasz Cyrkot

引用次数: 0

Firefighters’ knowledge of the knowledge of procedures for clearing the respiratory tract in an injured person with suspected infection with biological material (SARS-CoV-2) — a nationwide cross- -sectional study 消防员对疑似感染生物材料(SARS-CoV-2)的伤者呼吸道清理程序知识的了解情况——一项全国性的横断面研究

Medical Research Journal Pub Date : 2022-11-25 DOI: 10.5603/mrj.a2022.0049

Łukasz Dudziński, Piotr Konrad Leszczyński, Marcin Glinka, Marek Marzec, Michał Langner, Mariusz Feltynowski, M. Panczyk, P. Glinka

{"title":"Firefighters’ knowledge of the knowledge of procedures for clearing the respiratory tract in an injured person with suspected infection with biological material (SARS-CoV-2) — a nationwide cross- -sectional study","authors":"Łukasz Dudziński, Piotr Konrad Leszczyński, Marcin Glinka, Marek Marzec, Michał Langner, Mariusz Feltynowski, M. Panczyk, P. Glinka","doi":"10.5603/mrj.a2022.0049","DOIUrl":"https://doi.org/10.5603/mrj.a2022.0049","url":null,"abstract":"Introduction: The aim of the study was to assess the knowledge of the procedure for clearing the respiratory tract and updated qualified first aid (QFA) 1a and 2a procedures by firefighters serving in State Fire Service (SFS) rescue and firefighting units, and their knowledge of the transmission of the SARS-CoV-2 virus. Material and methods: The cross-sectional study covered 19 408 firefighters (officers serving in SFS rescue and firefighting units from all over Poland). The study was conducted using the diagnostic survey method, the Computer Assisted Web Interview (CAWI) technique consisting of a set of particulars regarding a specific officer and the appropriate medical part of the survey. Results: In the group of 19,408 respondents, 99.31% were men (n = 19,275), while women accounted for 0.69% (n = 133; p < 0.001). The age of the respondents was in the range of 18–66 years, and the average age was 35.88 ± 7.14 years. The length of service was 11.95 ± 6.44 years. The knowledge of procedures 1a and 2a declared by the respondents [OR = 1.51 (95% CI: 1.22–1.86), x 2 = 14.76], the ability to operate a suction unit [OR = 1.73 (95% CI: 1.44–2.08, x 2 = 34.58)], the frequency of airway clearance training (p < < 0.001, x 2 = 61.74). Only 15% of respondents used a suction unit on an injured person during operations. Conclusions: The knowledge of firefighters in the subject matter covered by the analysis is diverse, some firefighters have additional experience and practice from working in health care units. Professional development in the field of QFA supplemented with procedures 1a and 2a may translate into a lower risk of infection associated with airway clearing in the era of the pandemic. There is a visible need for constant training of SFS officers in terms of medical activities to maintain the knowledge of firefighters at a high initial level.","PeriodicalId":18485,"journal":{"name":"Medical Research Journal","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78563501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Granulocyte transfusion vs. neutropenia — is there a chance to win this battle? 粒细胞输注与中性粒细胞减少症——有机会赢得这场战斗吗?

Medical Research Journal Pub Date : 2022-11-22 DOI: 10.5603/mrj.a2022.0048

Artur Szumowski, P. Radziwon

引用次数: 0

Imported parasitosis as a diagnostic challenge in Primary Healthcare Clinic in the non-endemic region — a case study of schistosomiasis in English Division student 输入性寄生虫病对非流行地区初级卫生保健诊所诊断的挑战——英语科学生血吸虫病个案研究

Medical Research Journal Pub Date : 2022-11-18 DOI: 10.5603/mrj.a2022.0047

J. Gałązka, Dorota Starownik, B. Kasztelan-Szczerbińska, H. Cichoż-Lach

引用次数: 0

Post-COVID-19 rehabilitation (PCR-SIRIO 8) study. A rationale and protocol of the study covid -19后康复(PCR-SIRIO 8)研究。研究的基本原理和方案

Medical Research Journal Pub Date : 2022-10-26 DOI: 10.5603/mrj.a2022.0046

A. Kubica, P. Michalski, Łukasz Pietrzykowski, Alicja Rzepka-Cholasińska, A. Kosobucka-Ozdoba, Małgorzata Jasiewicz, E. Laskowska, Jacek Kryś, M. Ostrowska

引用次数: 1

Icaritin induces apoptosis and downregulates RhoA/ROCK pathway in the A549 adenocarcinoma cell line 淫羊藿苷诱导A549腺癌细胞凋亡，下调RhoA/ROCK通路

Medical Research Journal Pub Date : 2022-09-30 DOI: 10.5603/mrj.2022.0045

A. Żuryń, Adrian Krajewski

{"title":"Icaritin induces apoptosis and downregulates RhoA/ROCK pathway in the A549 adenocarcinoma cell line","authors":"A. Żuryń, Adrian Krajewski","doi":"10.5603/mrj.2022.0045","DOIUrl":"https://doi.org/10.5603/mrj.2022.0045","url":null,"abstract":"Introduction: Icaritin is a prenylflavonoid derivative from a traditional Chinese herb, Epimedium Genus. Icaritin exerts its anti-tumour effects in various cancers mainly by inhibiting cell proliferation, inducing cell differentiation and apoptosis, and suppressing cell migration and invasion. The study aimed to evaluate the effect of icaritin on apoptosis, cell cycle, and expression of selected cell cycle proteins: RhoA, ROCK1, and ROCK2 in the A549 cell line. Methods: Apoptosis and the cell cycle distribution were evaluated by flow cytometry. Protein expression was measured by conducting a western blot assay and immunofluorescence staining. Results and conclusions: The study revealed that icaritin induces apoptosis and cell cycle arrest in the G2/M phase in A549 cells. The authors showed that icaritin activates the p53 protein and downregulates Rho/ROCK pathway. Additionally, the decrease in expression of thrombospondin-1 was observed which can be part of the cytoprotective response of A549 cells on ICT treatment. The present study investigates the antitumour prop-erties of icaritin and conducts molecular analysis to show that ICT exerts its effect via the RhoA/ROCK pathway.","PeriodicalId":18485,"journal":{"name":"Medical Research Journal","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82643909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1