Sağlık Bilimleri Dergisi最新文献

ANTIPROLIFERATIVE AND ANTIOXIDANT EFFECTS OF CARNOSIC ACID ON HUMAN LIVER CANCER CELLS 肉豆蔻酸对人类肝癌细胞的抗增殖和抗氧化作用

Sağlık Bilimleri Dergisi Pub Date : 2024-02-22 DOI: 10.34108/eujhs.1313433

Ugur Akin, Elçin Bakır, Aysun ÖKÇESİZ HACISEYİTOĞLU, A. Eken

{"title":"ANTIPROLIFERATIVE AND ANTIOXIDANT EFFECTS OF CARNOSIC ACID ON HUMAN LIVER CANCER CELLS","authors":"Ugur Akin, Elçin Bakır, Aysun ÖKÇESİZ HACISEYİTOĞLU, A. Eken","doi":"10.34108/eujhs.1313433","DOIUrl":"https://doi.org/10.34108/eujhs.1313433","url":null,"abstract":"The purpose of the study was to investigate the cytotoxic effects of carnosic acid alone and in combination with cisplatin on human liver cancer cells and their capacity to scavenge reactive oxygen species induced in the presence or absence of hydrogen peroxide.Cytotoxic effects of agents on human liver cancer cells for 24 and 48 hours were evaluated by methyl-thiazol tetrazolium-bromide assay. Mitochondrial membrane potential were detected JC-1 kit. The intracellular reactive oxygen species levels were determined using 2’-7’dichlorofluorescin diacetateassay. According to our findings, both carnosic acid alone and in combination with cisplatin showed cytotoxic effects in human liver cancer cells at 24 and 48 hours of exposure. In particular, it was seen that the cell viability significantly decreased in a dose-dependent manner at 48 hours of exposure, and the combined treatment was found to have a more pronounced cytotoxic effect. In addition, all carnosic acid concentrations alone and in combination with cisplatin were identified to significantly reduce mitochondrial membrane potential. We observed that both carnosic acid alone and in combination with cisplatin lowered intracellular reactive oxygen species levels in the presence or absence of hydrogen peroxide. The results suggested that carnosic acid alone or in combination with cisplatin might be a promising agent in the treatment of liver cancer.","PeriodicalId":184686,"journal":{"name":"Sağlık Bilimleri Dergisi","volume":"25 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140440502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A VIEW ON PATIENT SAFETY: ASSESSMENT OF NURSES’ INFORMATION SECURITY AWARENESS LEVEL 病人安全观：评估护士的信息安全意识水平

Sağlık Bilimleri Dergisi Pub Date : 2024-02-22 DOI: 10.34108/eujhs.1327158

B. Özlük, Melek Çakir

{"title":"A VIEW ON PATIENT SAFETY: ASSESSMENT OF NURSES’ INFORMATION SECURITY AWARENESS LEVEL","authors":"B. Özlük, Melek Çakir","doi":"10.34108/eujhs.1327158","DOIUrl":"https://doi.org/10.34108/eujhs.1327158","url":null,"abstract":"Bu çalışmada, hemşirelerin bilgi güvenliği farkındalık düzeyini belirlemek amaçlandı. Tanımlayıcı tipteki çalışma, Ankara ilindeki bir eğitim ve araştırma hastanesinde çalışan 294 hemşire ile Haziran-Ağustos 2022 tarihleri arasında gerçekleştirildi. Veriler, Tanıtıcı Özellikler Formu ve Bilgi Güvenliği Ölçeği ile toplandı. Veri analizinde tanımlayıcı istatistikler, bağımsız örneklem t testi ve tek yönlü varyans analizi kullanıldı. Hemşirelerin %47.3’ünün bilgi güvenliğine yönelik bir eğitim almadığı ve %97.6’sının hastane bilgi sistemine girişte şifre kullandığı saptandı. Ayrıca hemşirelerin %33.3’ünün diğer kliniklerdeki hastalara ait bilgilere kolaylıkla ulaşabildiği ve %39.1’inin ise hastalara ait olan bilgilerin paylaşımı için hastadan onam almadığı belirlendi. Tanıtıcı Özellikler Formu ve Bilgi Güvenliği Ölçeği’nden alınan toplam puan ortalaması (3.21±0.53), hemşirelerin bilgi güvenliği farkındalığının orta düzeyde olduğunu gösterdi. Ölçek alt boyutlarından en yüksek puan hizmet sunumu (3.50±0.85), en düşük puan ise güvenlik politikası alt boyutundan (2.93±0.85) alındı. Hemşirelerin yaş, cinsiyet, eğitim durumu ve çalışma şekli gibi tanıtıcı özellikleriile Tanıtıcı Özellikler Formu ve Bilgi Güvenliği Ölçeği toplam ve alt boyut puan ortalamalarının karşılaştırılması sonucunda istatistiksel olarak anlamlı bir farkın olmadığı belirlendi (p>0.05).Hemşirelerin bilgi güvenliği farkındalığının orta düzeyde olması, veri güvenliğini tehdit etmekte ve sağlık hizmet kalitesini olumsuz etkilemektedir. Hemşirelerin bilgi güvenliği farkındalığını artırmak, kaliteli ve güvenli sağlık bakım hizmet sunumunu sağlamak için hizmet içi eğitimler düzenlenmelidir.","PeriodicalId":184686,"journal":{"name":"Sağlık Bilimleri Dergisi","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140441745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

METACOGNITION AND RUMINATIVE THOUGHT IN DEPRESSED INDIVIDUALS 抑郁症患者的元认知和反刍思维

Sağlık Bilimleri Dergisi Pub Date : 2024-02-21 DOI: 10.34108/eujhs.1382283

M. Evli, Nuray Şimşek, Tülay YILMAZ BİNGÖL, Zehra Su Topbaş

引用次数: 0

LIFE ADJUSTMENT ANALYSES OF THE PEOPLE WITH CORONA VIRUS IN TURKEY. A CROSS-SECTIONAL STUDY 土耳其科罗娜病毒感染者的生活适应分析。横断面研究

Sağlık Bilimleri Dergisi Pub Date : 2024-02-16 DOI: 10.34108/eujhs.1317206

Selma Kahraman, Arzu Ti̇muçi̇n, Zeynep İbaer

{"title":"LIFE ADJUSTMENT ANALYSES OF THE PEOPLE WITH CORONA VIRUS IN TURKEY. A CROSS-SECTIONAL STUDY","authors":"Selma Kahraman, Arzu Ti̇muçi̇n, Zeynep İbaer","doi":"10.34108/eujhs.1317206","DOIUrl":"https://doi.org/10.34108/eujhs.1317206","url":null,"abstract":"We aimed to determine the life adjustment process of people who have had coronavirus andthe factors affecting this process, to investigate the long-term effects related to this disease and reportthem for the first time.In thiscross-sectional study conductedbetween March and December 2021, 202 participants who previously had coronavirus infection, identified by reverse transcription polymerase chain reaction test, were enrolled. The data was collected online using the Hacettepe Personality Inventoryandevaluatedusing descriptive statistics, survival analyses and Kaplan–Meier survival analyses in SPSS software. According to the Hacettepe personality inventory, the mean total adjustment score of the participants was 91.97±16.9, the mean social adjustment score was 45.47±9.7 and the mean personal adjustment score was 46.49±8.7. According to the hazard function graphs, it was calculated that the mean general adjustment month of the participants was 13.59±0.64, the mean social adjustment month was 13.89±0.65 and the mean personal adjustment month was 11.83±0.52. It has been observed that the coronavirus disease has a negative impact on life and social and personal adjustment, while the mean time for people to adjust to life is 1 year.","PeriodicalId":184686,"journal":{"name":"Sağlık Bilimleri Dergisi","volume":"328 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140454523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ERGENLERDE COVID-19 FOBISI VE UYKU KALİTESİ covid-19恐惧症与青少年的睡眠质量

Sağlık Bilimleri Dergisi Pub Date : 2024-02-13 DOI: 10.34108/eujhs.1269206

Yeşim Zülkar, Gokce Demir

引用次数: 0

A REVIEW ON HEALTHCARE QUALITY INDICATORS AND UNEXPECTED EVENTS APPROACHES IN GERMANY AND TURKEY 德国和土耳其医疗质量指标和突发事件处理方法综述

Sağlık Bilimleri Dergisi Pub Date : 2024-02-11 DOI: 10.34108/eujhs.1332514

Oğuzhan Özmen, Hatice Semrin TİMLİOĞLU İPER

{"title":"A REVIEW ON HEALTHCARE QUALITY INDICATORS AND UNEXPECTED EVENTS APPROACHES IN GERMANY AND TURKEY","authors":"Oğuzhan Özmen, Hatice Semrin TİMLİOĞLU İPER","doi":"10.34108/eujhs.1332514","DOIUrl":"https://doi.org/10.34108/eujhs.1332514","url":null,"abstract":"Evaluation of quality studies in order to ensure patient safety is possible by measuring quality. \"Quality Indicators\" are used for this. In order to determine indicators and for realistic measurements, detecting and reporting unexpected events that have arisen on the basis of these indicators reveal invaluable results for the development of health systems.Germany, which is a developed country and a member of the European Union, and Turkey, which is a developing country on the way to the European Union, were compared in the focus of quality indicators and unexpected events in focus of “Quality Practices in Healthcare” in study.It is aimed to recognize the Quality of Health Care as a result of comparative evaluation, to discuss the positive and negative aspects of the two countries' quality indicators and their approaches to unexpected events, and to suggest alternative methods for application updates.In conclusion; In Germany, the Quality Program can be defined as a \"Data-Based Quality Program with Wide Participation\". Hospitals are encouraged for Unexpected Event Notifications in Germany, they are directed towards quality, and quality competition which created in healthcare services. However, when the payments and financial concerns are taken into consideration, it is felt that this competition cannot be achieved only by publishing the quality indicators to the public. Although a very good level has been achieved in the system that will enable the use of quality indicators in Turkey, there are problems in unexpected event notification, use of quality indicators and sharing of results.","PeriodicalId":184686,"journal":{"name":"Sağlık Bilimleri Dergisi","volume":"16 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140458734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DIAGNOSTIC AND PROGNOSTIC ROLE OF PERIOSTIN IN RESPIRATORY SYSTEM DISEASE COMPLEX IN CALVES 犊牛呼吸系统疾病综合征中包膜生长因子的诊断和预后作用

Sağlık Bilimleri Dergisi Pub Date : 2024-02-08 DOI: 10.34108/eujhs.1367430

Derviş Baran, İhsan Keleş

{"title":"DIAGNOSTIC AND PROGNOSTIC ROLE OF PERIOSTIN IN RESPIRATORY SYSTEM DISEASE COMPLEX IN CALVES","authors":"Derviş Baran, İhsan Keleş","doi":"10.34108/eujhs.1367430","DOIUrl":"https://doi.org/10.34108/eujhs.1367430","url":null,"abstract":"The purpose of this study was to compare the amounts of serum amyloid a, haptoglobin, fibrinogen, and periostin in calves with respiratory system disease complex before and after treatment. Three groups were used in the study: an acute group (n=10) made up of calves with acute respiratory system disease complex symptoms, a chronic group made up of calves with chronic respiratory system disease complex symptoms, and a control group made up of disease-free, healthy calves. Before and after therapy (day 0, 7 and 14), clinical examinations were performed and blood samples were taken from the acute and chronic groups. Calves in the control group only had one clinical evaluation and blood sample collection. Results showed that both the acute and chronic groups exhibited clinical improvement after treatment. Before treatment, the concentrations of fibrinogen, serum amyloid A, and haptoglobin in the acute and chronic groups were significantly higher than those in the control group (p0.05).Based on the findings, it can be concluded that haptoglobin, serum amyloid A, and fibrinogen values, rather than periostin, play an important role in supporting the diagnosis and prognosis of respiratory system disease complex in calves.","PeriodicalId":184686,"journal":{"name":"Sağlık Bilimleri Dergisi","volume":"51 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140460000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE EFFECT OF FUTURE EXPECTATION ON HAPPINESS AND HEALTHY LIFESTYLE BELIEF IN ADOLESCENTS: A STRUCTURAL EQUALITY MODEL 未来预期对青少年幸福感和健康生活方式信念的影响：结构平等模型

Sağlık Bilimleri Dergisi Pub Date : 2024-02-05 DOI: 10.34108/eujhs.1376049

Necmettin Çi̇ftci̇, A. Sarman

引用次数: 0

ACİL SERVİS HEMŞİRELERİNİN YORGUNLUK DÜZEYİNİ VE DEVİR TESLİM ETKİNLİĞİNİ ETKİLEYEN FAKTÖRLER ÜZERİNE BİR DEĞERLENDİRME 对影响急诊科护士疲劳程度和交接班效率的因素进行评估

Sağlık Bilimleri Dergisi Pub Date : 2024-01-24 DOI: 10.34108/eujhs.1325592

Ali Kaplan

引用次数: 0

ÇOCUK DİŞ HEKİMLERİNİN PROBİYOTİKLERLE İLGİLİ BİLGİ, GÖRÜŞ VE TUTUMLARININ DEĞERLENDİRİLMESİ 评估儿科牙医对益生菌的认识、看法和态度

Sağlık Bilimleri Dergisi Pub Date : 2024-01-22 DOI: 10.34108/eujhs.1376821

Ecem AKBEYAZ ŞİVET, İrem Gümüşkaya, Betul Kargul

{"title":"ÇOCUK DİŞ HEKİMLERİNİN PROBİYOTİKLERLE İLGİLİ BİLGİ, GÖRÜŞ VE TUTUMLARININ DEĞERLENDİRİLMESİ","authors":"Ecem AKBEYAZ ŞİVET, İrem Gümüşkaya, Betul Kargul","doi":"10.34108/eujhs.1376821","DOIUrl":"https://doi.org/10.34108/eujhs.1376821","url":null,"abstract":"Probiyotiklerin ağız sağlığı üzerindeki etkileri üzerine araştırmalar artmaktadır. Fakat dişhekimlerinin probiyotik ürünlere ilişkin bilgi ve tutumları ve bunların probiyotik ürünlerin tüketimi üzerindeki etkisi hakkındaki bilgi sınırlıdır. Bu çalışmanın amacı Türkiye'deki çocuk diş hekimlerinin probiyotiklerle ilgili bilgi, görüş ve tutumlarının değerlendirilmesidir.Ankete 100 çocuk diş hekimi (80 kadın, 20 erkek) katılmıştır. Katılımcıların %44'ü çocuk diş hekimliği alanında doktora veya uzmanlık öğrencileri iken; 15 yılı aşkın mesleki deneyimi olanların oranı %24'tür. Çalışmaya katılanların %83'ü probiyotiklerle ilgili tanımlamayı doğru işaretlerken; %30'u probiyotiklerin sadece bakteriler olduğunu ifade etmiştir. Çocuk diş hekimlerinin %66'sı probiyotiklerleilgili kendilerinin \"orta\", \"iyi\" veya \"çok iyi\" bilgi düzeyine sahip olduğunu belirtmiştir ve bu oran, çocuk diş hekimliğialanındaki akademik derece ile istatistiksel olarak anlamlı bulunmamıştır (p=0.077). Çocuk diş hekimlerinin %64'ü probiyotik ürünlerin kullanımını hastalarına önermiştir ve en çok (%79.4) antibiyotik tedavisi sırasında koruyucu amaçla tavsiye etmişlerdir.Bu çalışmaya katılan çocuk diş hekimlerinin probiyotikler hakkındaki bilgi düzeyinin yeterli olduğu sonucuna varılmıştır. Katılımcılar probiyotik kullanımıyla ilgili olumlu görüşe sahiplerdir ancak hastalara probiyotik kullanımını önerme konusunda daha düşük bir oran bulunmuştur.","PeriodicalId":184686,"journal":{"name":"Sağlık Bilimleri Dergisi","volume":"58 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140499685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0