DIAGNOSTIC AND PROGNOSTIC ROLE OF PERIOSTIN IN RESPIRATORY SYSTEM DISEASE COMPLEX IN CALVES

The purpose of this study was to compare the amounts of serum amyloid a, haptoglobin, fibrinogen, and periostin in calves with respiratory system disease complex before and after treatment. Three groups were used in the study: an acute group (n=10) made up of calves with acute respiratory system disease complex symptoms, a chronic group made up of calves with chronic respiratory system disease complex symptoms, and a control group made up of disease-free, healthy calves. Before and after therapy (day 0, 7 and 14), clinical examinations were performed and blood samples were taken from the acute and chronic groups. Calves in the control group only had one clinical evaluation and blood sample collection. Results showed that both the acute and chronic groups exhibited clinical improvement after treatment. Before treatment, the concentrations of fibrinogen, serum amyloid A, and haptoglobin in the acute and chronic groups were significantly higher than those in the control group (p0.05).Based on the findings, it can be concluded that haptoglobin, serum amyloid A, and fibrinogen values, rather than periostin, play an important role in supporting the diagnosis and prognosis of respiratory system disease complex in calves.