Materiale Plastice最新文献

{"title":"In Vitro Evaluation of PEGDA-Based RGD Hydrogels forAttenuating Antiphospholipid Antibodies-Induced PlateletAggregation and Trophoblast Dysfunction","authors":"NAN SHENG, YI TANG, JIAHUI QIAN, Jingwen Xu, Yunzhao Xu","doi":"10.37358/mp.2026.070673","DOIUrl":"https://doi.org/10.37358/mp.2026.070673","url":null,"abstract":"","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://revmaterialeplastice.ro/pdf_online/RevChim_MP_70673.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148672253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative Localized Nanoparticle Delivery Combined withGene Therapy for Colorectal Cancer Recurrence Suppression","authors":"JUN ZHU, FAJING CHEN, WEI CAO, YULU DING, LI MING, ZHENYU FAN, HAIPENG GE, YANG YANG, HONG SHEN, XIAODI YAN","doi":"10.37358/mp.25.4.68423","DOIUrl":"https://doi.org/10.37358/mp.25.4.68423","url":null,"abstract":"Background: Postoperative recurrence remains a major challenge in colorectal cancer due to residual tumor cells that survive surgical resection.Systemic chemotherapy is often insufficient for complete local control and causes systemic toxicity.Combining local chemotherapy with gene silencing may offer a more effective and targeted strategy.Methods: We developed PLGA-based nanoparticles co-loaded with irinotecan and Bcl-2-targeting siRNA.The nanoparticles were characterized for morphology, encapsulation efficiency, release kinetics, cellular uptake, cytotoxicity, gene silencing efficiency, and in vivo efficacy using a murine tumor resection model.Results: The dual-loaded nanoparticles exhibited uniform spherical morphology, high encapsulation efficiencies (82.3% for irinotecan and 69.5% for siRNA), and sustained release of both agents.Conclusion: This localized combinatorial delivery system provides a synergistic approach for eliminating residual tumor cells and preventing recurrence after colorectal cancer surgery, demonstrating high therapeutic potential and translational value.","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":"62 4","pages":"22-33"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://revmaterialeplastice.ro/pdf/3. RevChim_MP_68423.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147880012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response Surface Optimization of the Alkaline ExtractionProcess of Ganoderma lucidum Polysaccharides and PreliminaryStudy on Their Immunological Activity","authors":"CHUANLI JIN, Ruijuan Ma, Chen Chen, ZE DANG, Tong Yu, Yu Fu, Juan Du","doi":"10.37358/mp.25.3.5780","DOIUrl":"https://doi.org/10.37358/mp.25.3.5780","url":null,"abstract":"Objective: To investigate and optimize the alkaline extraction process of Ganoderma lucidum polysaccharides, and to preliminarily explore their immunological activity.Methods: Ganoderma lucidum was used as the raw material for the extraction of polysaccharides.A single-factor experiment was conducted to examine the effects of NaOH concentration, temperature, and extraction time on the total sugar content of the polysaccharides.Based on these results, response surface methodology was applied to optimize the extraction process.The total polysaccharide content, uronic acid content, monosaccharide composition, molecular weight, and cell viability were measured.Results: The optimal extraction conditions were found to be a temperature of 93 C, NaOH concentration of 0.40 mol/L, and extraction time of 172 min, yielding a total polysaccharide content of 47.66%.The monosaccharide composition of the extracted polysaccharides included mannose, glucuronic acid, glucose, galactose, arabinose, and fucose.Molecular weight analysis revealed two average molecular weights, 3.15 10 4 Da and 1.014 10 4 Da, indicating the polysaccharides were relatively small.Infrared spectroscopy showed the presence of -type glycosidic linkages in the polysaccharides.In the cell viability assay, GLCP-1 enhanced the viability of RAW264.7 cells and significantly inhibited the viability of HepG2 cells.However, the specific regulatory mechanism remains unclear.Conclusion: The study successfully optimized the alkaline extraction of Ganoderma lucidum polysaccharides and demonstrated their potential immunological activity, providing a foundation for the future exploration of their bioactivity and industrial production.","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":"62 3","pages":"55-71"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://revmaterialeplastice.ro/pdf/RevChim_MP_68457.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147884263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polyethylene Terephthalate Nanofiber Mats for BarrierMembranes in Guided Bone Regeneration","authors":"MINGZHOU WU, JINJIE CHU, Jiang Li, ZHAOJUN WANG, Tingting Xu, Feng Su, WENCHAO ZHOU, Huanhuan Feng, Lei Gu, Pan Hu","doi":"10.37358/mp.25.3.68419","DOIUrl":"https://doi.org/10.37358/mp.25.3.68419","url":null,"abstract":"Background: Barrier membranes prevent soft tissue invasion while promoting bone healing, suggesting a potential significance in guided bone regeneration (GBR).However, many resorbable membranes lack adequate mechanical strength and long-term stability.Polyethylene terephthalate (PET), a biostable polymer, exhibits promising properties for GBR but remains underexplored.Methods: Electrospun PET nanofiber membranes (PET-1 to PET-4) were fabricated by systematically varying solution concentrations and processing conditions.Their morphology was analyzed by scanning electron microscopy (SEM), and mechanical properties were assessed via tensile testing.Surface wettability was reflected by the water contact angle.In vitro biocompatibility was evaluated using the CCK-8 assay using L929 mouse fibroblasts.Barrier function was tested by Transwell and time-course fibroblast migration assays.Results: All PET membranes exhibited uniform nanofiber structures with good mechanical integrity.PET-4 showed the highest tensile strength (13.5 MPa) and elastic modulus (190 MPa).Contact angles ranged from 85 to 93 , which indicated moderate hydrophobicity.Cytocompatibility was high across all the groups, with PET-4 representing nearly 100% cell viability.In migration assays, PET-4 significantly suppressed fibroblast invasion over 48 h.Conclusion: Electrospun PET nanofiber membranes demonstrated excellent mechanical performance, cytocompatibility, and barrier function.PET-4 emerged as a particularly promising candidate for GBR application, offering effective long-term soft tissue exclusion and bone regeneration support.","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":"62 3","pages":"23-33"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://revmaterialeplastice.ro/pdf/RevChim_MP_68419.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147887197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Sliding Speed and Glass Bead Concentration on 3D Roughness Parameters","authors":"L. Deleanu, Laura Maftei, G. Ojoc, Alina Ceoromila, L. C. Titire, C. Georgescu","doi":"10.37358/mp.23.4.5691","DOIUrl":"https://doi.org/10.37358/mp.23.4.5691","url":null,"abstract":"\u0000This paper presents an analysis of 3D amplitude and functional parameters for worn surfaces of composites with polyamide 6 as matrix and different glass bead concentrations (0%, 2.5%, 5%, 10%, 20%, 30% and 50%wt). The worn surfaces after dry sliding of a steel pin on a disk, for 10 km, at constant velocity (0.5 m/s, 1 m/s and 1.5 m/s) and under an average pressure of 1 MPa. There were done two tests under the same conditions. On each worn track, there were investigated three surfaces of 500 μm x 500 μm with a contact profilometer. The number of points on the scan line was 200 points and the step between lines was 5μm. The following amplitude parameters were measured and calculated for assessed surfaces: the arithmetic mean deviation, Sa, the root mean square deviation, Sq, the maximum height of surface prominence, Sp, the maximum surface depth, Sv, the maximum height, St, the skewness factor, Ssk and the kurtosis, Sku. The discussed functional parameters are the reduced peak height, Spk, the height of the core of the surface, Sk and the depth of the valley zone, Svk. The comparison of their values makes posible to evaluate if the worn surface could function in a new running or the replacement of the component is recommended. Considering that machine components have intermittent operation, these worn surfaces becoming initial surfaces for the following cycle of contact operation. Based on the average values of amplitude and functional parameters, it was found that a relatively good surface quality is preserved for concentrations of 10...30%wt glass beads, for v=0.5...1 m/s (Sa and Sq having similar trend); for lower concentrations and for 50% glass beads, the parameter values increase but without identifying a distinct relationship with the working regime, especially for 2.5 and 5% glass beads.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":"37 3","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Removal of Aromatic Amino-derivatives from Aqueous Solutions Using Polymeric Supports Functionalized with Aminophosphonated/aminoacid-phosphonated Groups","authors":"R. Ardelean, Adriana Popa, Ecaterina-Stela Dragan, C. Davidescu","doi":"10.37358/mp.23.4.5685","DOIUrl":"https://doi.org/10.37358/mp.23.4.5685","url":null,"abstract":"\u0000Aromatic amines are the significant compounds used as intermediates in the organic synthesis, for obtaining such as azo dyes, antioxidants, fuel additives, corrosion inhibitors, pesticides, antiseptic agents, poultry medicine, and pharmaceutical synthesis. However, the presence of aromatic amines in water, even at very low concentrations, is extremely harmful to aquatic life and human health. Pollution of natural waters by aromatic amines is a serious environmental concern. The aim of this work was to obtain new adsorbents for use in the removal of aromatic amines from aqueous solutions. Styrene-15%divinylbenzene copolymers grafted with aminophosphonate groups (code: AP-S15%DVB) and amino acid-phosphonate groups (code: AM-S15%DVB) were used for the removal of pollutants such as: aniline, 2-methyl-aniline and 4-methyl-aniline. The adsorption capacity and the adsorption kinetic using the pseudo-first order and pseudo-second order equations were examined. From a kinetic point of view, it was established that the adsorption of the studied amino derivatives on the used adsorbents took place according to the pseudo-second order model. It was found that the adsorption rate constant increased with the increase of temperature, so the speed of the adsorption process increased. The obtained results confirm that the polymer adsorbents studied can be successfully used for the removal of aromatic amino derivatives from aqueous solutions for the purpose of wastewater treatment.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":"55 4","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical Properties of PMMA and PLA Modified Epoxy Resins","authors":"Ana Miroznicenco, Gabriel Saracu, V. Bria, M. Gorovei, A. Cîrciumaru","doi":"10.37358/mp.23.4.5696","DOIUrl":"https://doi.org/10.37358/mp.23.4.5696","url":null,"abstract":"\u0000Last years research in polymers registered an increase of interest regarding polymer mixtures aiming to obtain materials with properties of the mixed polymers. In this respect many studies are pointing the mixtures between a thermoset polymer and a thermoplastic polymer. It is known the fact that thermoplastic polymers are much more malleable than the thermoset ones and the goal is to obtain a mixture with the general properties of the thermoset polymer and with a machining ability proper to the thermoset polymer. The vitrimers are this type of polymers and, some of them, can be obtained by mixing polymers form the two categories. This study is about using solutions of two thermoset polymers to modify the basic properties of three epoxy resins. The results show that the presence of PMMA, respectively, PLA inside the epoxy resin matrix determines changes of the mechanical properties of the formed materials. Without analysing the adhesive properties of new materials is hard to decide about their value from the composites applications point of view.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":"65 12","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139450067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Phenolic Resin Coating Thickness on Mechanical Properties and Corrosion Resistance of Metal Materials","authors":"Diyao Zhang, L. Yuan, Jingkun Yu","doi":"10.37358/mp.23.4.5684","DOIUrl":"https://doi.org/10.37358/mp.23.4.5684","url":null,"abstract":"\u0000In the realm of petrochemical and other industries, metal materials face threats such as impact and high-temperature electrochemical corrosion. Consequently, there has been significant attention towards organic coatings that effectively attenuate impact forces while simultaneously providing a barrier against corrosive agents. The thermosetting phenolic resin 2130, known for the facile curing process, exceptional thermal stability, water resistance, corrosion resistance, and superior mechanical properties post-curing, finds extensive applications in the field of coatings. To address the challenge of depositing a complete and uniform resin coating on complex workpieces, coatings with varying thicknesses on the surface of 304 stainless steel were deposited via rotary evaporation combined with long-term low-temperature drying. The relationship between coating thickness and mechanical properties, as well as corrosion resistance, was investigated and analyzed through a comprehensive approach involving mechanical testing, electrochemical analysis, and long-term service weight loss assessment. The results demonstrated that the coatings deposited on the metal surface exhibited excellent integrity and compactness. Moreover, an increase in coating thickness led to a significant reduction in material corrosion rate. The coatings exhibited excellent substrate adhesion and flexibility, thereby providing effective protection against impact on the metal substrate. The relationship between the thickness of the coating and the surface roughness was evident, while the flexibility of the coating first increased and then decreased with the increase of coating thickness. When the coating thickness was 7 μm, the maximum surface roughness of the coating measured 0.44 μm. Under these conditions, the impact toughness of the coating reached the peak, exhibiting a ductile fracture mode and showcasing superior comprehensive mechanical properties. The findings of this study will offer theoretical support for the investigation and formulation of resin coatings in subsequent industrial production.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":"62 9","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Finite Element Modeling of the Thermomechanical Behavior of Polyethylene","authors":"Sana Ben Khlifa, Ltaief Lammari, Wajdi Chtourou, H. Kharroubi","doi":"10.37358/mp.23.4.5686","DOIUrl":"https://doi.org/10.37358/mp.23.4.5686","url":null,"abstract":"\u0000This article presents a finite element study based on tests of characterizations to find the properties of the materials studied, the injection-blowing technique, chosen in this case, is characterized by the bi-axial of the material, and one benefits from the orientation of the macromolecules in the directions of use of the material. The objective of this work is to link all the mechanical and thermal parameters during the treatment of molten polymer materials subjected to high-stress rates that can lead to significant temperature increases due to viscous heating in the order of 200�C. Predicting the temperature range is essential for good temperature control and is a major factor in determining the quality of the final product. This forces us to choose an adequate law of behavior, capable of translating the mechanical evolution under the thermal effect while explaining the rheological response of the viscoelastic metal. So this process is usually accompanied by geometric defects resulting from the original residual stresses cooling speed and the process itself. In the packaging of food products, as in this case, the bottles require to have a stable filling and a certain storage capacity.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":"58 10","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PLGA - gallic Acid Advanced Drug Delivery System as New Functional Material","authors":"Anne-Marie Beatrice Poenariu, Roberto Angelo Postelnicu, M. Ciocîlteu, Gabriela Rau, Mariana Popescu, A. Simionescu, Ionela Andreea Neacsu, C. Nicolicescu, D. Amzoiu","doi":"10.37358/mp.23.4.5688","DOIUrl":"https://doi.org/10.37358/mp.23.4.5688","url":null,"abstract":"\u0000Combining polimers with polyphenols such as gallic acid opens up new directions in healthcare system. By encapsulating secondary metabollites within PLGA nanoparticles, we tried to enhance their stability, solubility, and obtain a targeted delivery system. In this study, we synthesized a PLGA-gallic acid sustained release system, using the solvent evaporation method. This approach improved the therapeutic efficacy of gallic acid. The numerical distribution showed that most PLGA-GA nanoparticles have a size of 10 nm. Through the method of solvent evaporation, an incorporation efficiency of 49% was obtained.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":"95 11","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139450272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}