The journal of medical investigation : JMI最新文献_第6页

Clinical Significance of High-intensity Zone for Discogenic Low Back Pain: A Review. 椎间盘源性腰痛高强度区临床意义综述。

The journal of medical investigation : JMI Pub Date : 1900-01-01 DOI: 10.2152/jmi.63.1

S. C. Jha, Kosaku Higashino, T. Sakai, Y. Takata, Mitsunobu Abe, Kazuta Yamashita, Masatoshi Morimoto, S. Fukuta, A. Nagamachi, K. Sairyo

{"title":"Clinical Significance of High-intensity Zone for Discogenic Low Back Pain: A Review.","authors":"S. C. Jha, Kosaku Higashino, T. Sakai, Y. Takata, Mitsunobu Abe, Kazuta Yamashita, Masatoshi Morimoto, S. Fukuta, A. Nagamachi, K. Sairyo","doi":"10.2152/jmi.63.1","DOIUrl":"https://doi.org/10.2152/jmi.63.1","url":null,"abstract":"High-intensity zone (HIZ) was originally described as a high-intensity signal on T2-weighted magnetic resonance (MR) images, located in the posterior annulus fibrosus, clearly separated from the nucleus pulposus. Among symptomatic patients with low back pain, HIZ is present in 28-59% of cases. In morphologically abnormal discs, high sensitivity and specificity of 81% and 79%, respectively, were reported for HIZs and concordant pain during discography. In contrast, another report indicated low rates. Although most papers reported high sensitivity and specificity for this relationship, it remains controversial. Regarding the pathology of HIZs, inflammatory granulation tissues are found at sites showing HIZs. Such inflammatory tissues produce pro-inflammatory cytokines and mediators, which sensitize the nociceptors within the disc and cause pain. An effective treatment for this condition is yet to be established. Recently, minimally invasive surgery using percutaneous endoscopic discectomy (PED) under local anesthesia was introduced. After removal of the degenerated disc material, the HIZ is identified with the endoscope and then coagulated and modulated with a bipolar radio pulse. This technique is called thermal annuloplasty. In conclusion, HIZs is an important sign of painful intervertebral disc disruption, if identified precisely based on factors such as location and intensity.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114793288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 31

The Effect of Laparoscopic Sleeve Gastrectomy on Obesity and Obesity-related Disease : the Results of 10 Initial Cases. 腹腔镜袖式胃切除术治疗肥胖及肥胖相关疾病10例初步结果

The journal of medical investigation : JMI Pub Date : 1900-01-01 DOI: 10.2152/jmi.66.289

H. Kashihara, M. Shimada, K. Yoshikawa, Jun Higashijima, T. Miyatani, T. Tokunaga, M. Nishi, C. Takasu, Y. Hamada

{"title":"The Effect of Laparoscopic Sleeve Gastrectomy on Obesity and Obesity-related Disease : the Results of 10 Initial Cases.","authors":"H. Kashihara, M. Shimada, K. Yoshikawa, Jun Higashijima, T. Miyatani, T. Tokunaga, M. Nishi, C. Takasu, Y. Hamada","doi":"10.2152/jmi.66.289","DOIUrl":"https://doi.org/10.2152/jmi.66.289","url":null,"abstract":"Introduction : The number of patients who undergo laparoscopic sleeve gastrectomy (LSG) has been increasing. Department of Surgery, Tokushima University performed the first LSG in 2013. The aim of this study was to report the results of the initial ten cases who underwent a LSG. Patients and methods : Ten obese patients : five males and five females ; age range from thirty-three years to fifty-six years (mean age 42.2 years) ; mean body mass index (BMI) 50.3 ; five with diabetes ; nine with hypertension (HT) ; four with hyperlipidemia (HL) ; eight with sleep apnea syndrome (SAS) who underwent LSG were enrolled in this study. The data was analyzed retrospectively and included short- and long-term outcomes. Results : There were no post-operative complications in this study. The %EWL at three and six months and one year post-operative were 44.2%, 50.2% and 48.6% respectively. In three months post-operative the non-alcoholic fatty liver (NAFLD) and non-alcoholic steatohepatitis (NASH) had improved transaminase (AST/ALT), liver to spleen ratio in plain CT value. Improvements were also evident in the obesity-related diseases : diabetes 80% (4/5) ; HT 67% (6/9) ; HL 75% (3/4) ; and SAS 88% (7/8). Conclusion : LSG is a promising option for the treatment of morbid obesity and obesity-related diseases. J. Med. Invest. 66 : 289-292, August, 2019.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127000627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Short-Term Outcomes of Laparoscopic Distal Gastrectomy for Advanced Gastric Cancer. 腹腔镜胃远端切除术治疗晚期胃癌的近期疗效。

The journal of medical investigation : JMI Pub Date : 1900-01-01 DOI: 10.2152/jmi.63.68

Masakazu Goto, H. Okitsu, Y. Yuasa, S. Kuramoto, A. Tomibayashi, Daisuke Matsumoto, Yuri Masuda, H. Edagawa, Ryotaro Tani, Osamu Mori, Y. Matsuo

{"title":"Short-Term Outcomes of Laparoscopic Distal Gastrectomy for Advanced Gastric Cancer.","authors":"Masakazu Goto, H. Okitsu, Y. Yuasa, S. Kuramoto, A. Tomibayashi, Daisuke Matsumoto, Yuri Masuda, H. Edagawa, Ryotaro Tani, Osamu Mori, Y. Matsuo","doi":"10.2152/jmi.63.68","DOIUrl":"https://doi.org/10.2152/jmi.63.68","url":null,"abstract":"The purpose of this study was to investigate the oncologic outcomes of laparoscopic distal gastrectomy (LDG) for advanced gastric cancer (AGC). Between April 2003 and March 2014, LDG was performed for 392 patients, 91 patients (23.2%) had histopathologically diagnosed AGC beyond T2 depth. The clinicopathological features, postoperative outcomes, mortality, morbidity, recurrence rate, and survivals of those patients were reviewed. The TNM stages of the tumor were IB in 26 patients (28.5%), IIA in 20 (21.9%), IIB in 18 (19.7%), IIIA in 13 (14.2%), IIIB in 6 (6.5%), IIIC in 6 (6.5%), and IV in 2 (2.1%). Major morbidity occurred in 14 patients (15.3%), with no postoperative mortality. Median follow-up was 24.5 months; 10 patients developed recurrence during the follow-up period, and 10 patients died, including 6 cancer deaths. The 5-year overall and disease-free survival rates were 76.8% and 72.6%, respectively. By stage, OS/DFS was 92.3%/91.8% in stage IB, 85.4%/85.4% in stage II, and 49.3%/26.9% in stage III. Oncologic outcomes were good in patients with AGC, especially with stage IB-IIB, who underwent LDG. LDG appears to be an effective approach for treating stage IB and II gastric cancer.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125121207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Sonographic evaluation of cervical nerve roots in ALS and its clinical subtypes. 肌萎缩侧索硬化症颈神经根及其临床亚型的超声评价。

The journal of medical investigation : JMI Pub Date : 1900-01-01 DOI: 10.2152/jmi.63.54

A. Mori, H. Nodera, N. Takamatsu, Keiko Maruyama-Saladini, Y. Osaki, Y. Shimatani, M. Oda, Y. Izumi, R. Kaji

{"title":"Sonographic evaluation of cervical nerve roots in ALS and its clinical subtypes.","authors":"A. Mori, H. Nodera, N. Takamatsu, Keiko Maruyama-Saladini, Y. Osaki, Y. Shimatani, M. Oda, Y. Izumi, R. Kaji","doi":"10.2152/jmi.63.54","DOIUrl":"https://doi.org/10.2152/jmi.63.54","url":null,"abstract":"Morphological assessment of peripheral nerves in amyotrophic lateral sclerosis (ALS) has been available by sonography. Detection of possible axonal atrophy could be important in predicting progression. Research on correlation between sonographic findings and clinical presentation has been sparse. The aim of the study was to assess possible motor axon loss in patients with ALS by sonography and to correlate the imaging features with clinical subtypes. Patients with either definite or probable ALS and control subjects had sonographic evaluation of the cervical nerve roots (C5, C6, and C7). Each diameter and their sums were measured. The ALS patients were classified by their clinical onset and progression (arm-onset, leg-onset, bulbar, and flail-arm variant) and the sonographic features were compared. Overall, the cervical nerve roots were thinner in ALS than in the controls, but the diagnostic sensitivity was low. The patients with arm dysfunctions tended to show thinner nerve roots than those with normal or relatively preserved arm functions. The four ALS subtypes showed similar diameters of the nerve roots. There was no correlation between the disease duration and the diameters of the nerve roots. Sonography of the cervical nerve roots showed axonal atrophy in ALS and potentially reflects subtle arm dysfunctions.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125172546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Treatment with DHA/EPA ameliorates atopic dermatitis-like skin disease by blocking LTB4 production. DHA/EPA治疗通过阻断LTB4的产生改善特应性皮炎样皮肤病。

The journal of medical investigation : JMI Pub Date : 1900-01-01 DOI: 10.2152/jmi.63.187

S. Yoshida, K. Yasutomo, Toshiyuki Watanabe

{"title":"Treatment with DHA/EPA ameliorates atopic dermatitis-like skin disease by blocking LTB4 production.","authors":"S. Yoshida, K. Yasutomo, Toshiyuki Watanabe","doi":"10.2152/jmi.63.187","DOIUrl":"https://doi.org/10.2152/jmi.63.187","url":null,"abstract":"Atopic dermatitis (AD) is caused by both dysregulated immune responses and an impaired skin barrier. Although leukotriene B4 (LTB4) is involved in tissue inflammation that occurs in several disorders, including AD, therapeutic strategies based on LTB4 inhibition have not been explored. Here we demonstrate that progression of an AD-like skin disease in NC/Nga mice is inhibited when docosahexaenoic acid (DHA)/eicosapentaenoic acid (EPA) is administered together with FK506. Treatment with DHA/EPA and FK506 decreases the clinical score of dermatitis in NC/Nga mice and lowers local LTB4 concentrations. The treatment also suppressed the infiltration of T cells, B cells, eosinophils and neutrophils, and promoted reduced serum IgE levels. Secretion of IL-13 and IL-17A in CD4(+) T cells was lower in DHA/EPA- and FK506-treated mice than in mice treated with FK506 alone. The inhibition of disease progression induced by DHA/EPA was reversed by local injection of LTB4, suggesting that the therapeutic effect of DHA/EPA is LTB4-dependent. Our results demonstrate that treatment of AD with DHA/EPA is effective for allergic skin inflammation and acts by suppressing LTB4 production. J. Med. Invest. 63: 187-191, August, 2016.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124332120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

Association of habitual high-fat intake and desire for protein and sweet food. 习惯性高脂肪摄入与对蛋白质和甜食的渴望有关。

The journal of medical investigation : JMI Pub Date : 1900-01-01 DOI: 10.2152/jmi.63.241

Hiroshi Tatano, H. Yamanaka-Okumura, Bei Zhou, Chisaki Adachi, Yuka Kawakami, T. Katayama, Masashi Masuda, E. Takeda, Y. Taketani

{"title":"Association of habitual high-fat intake and desire for protein and sweet food.","authors":"Hiroshi Tatano, H. Yamanaka-Okumura, Bei Zhou, Chisaki Adachi, Yuka Kawakami, T. Katayama, Masashi Masuda, E. Takeda, Y. Taketani","doi":"10.2152/jmi.63.241","DOIUrl":"https://doi.org/10.2152/jmi.63.241","url":null,"abstract":"Reducing dietary calorie density (CD) is useful in body weight management. This study investigates the association between dietary habits and preferences for different CDs. We conducted a randomized crossover study of 232 healthy subjects who consumed packed lunch boxes containing a control, high-meat and low-rice, low-vegetable, medium-fat and low-vegetable, high-fat, and high-fat and low-vegetable meals over six sessions. The subjective levels of sensory properties were assessed over time using a visual analog scale and the area under the curve. Subjects were assessed for dietary habits using a brief-type self-administered diet history questionnaire (BDHQ) and were divided into two groups based on a daily fat energy ratio ≥ 25% (high fat [HF], n=116) and < 25% (normal, n=116) that was matched for age, body mass index, and sex ratio. Our findings indicate that the desire for sweetness was higher in the HF group than in the normal group, regardless of the meals consumed. Particularly, among the 500-kcal low-CD meals, a high-protein meal provided greater fullness and satisfaction and lower prospective consumption in the HF group than in the normal group. Therefore, our study demonstrates that postprandial appetite sensation is associated with dietary habits of fat intake. J. Med. Invest. 63: 241-247, August, 2016.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122061399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Analysis of the Prognostic Factors of Extensive Disease Small-Cell Lung Cancer Patients in Tokushima University Hospital. 德岛大学医院广泛性小细胞肺癌患者预后因素分析。

The journal of medical investigation : JMI Pub Date : 1900-01-01 DOI: 10.2152/jmi.63.286

H. Ogino, M. Hanibuchi, S. Kakiuchi, Atsuro Saijo, Toshifumi Tezuka, Yuko Toyoda, Makoto Tobiume, K. Otsuka, Satoshi Sakaguchi, H. Goto, K. Arisawa, Y. Nishioka

{"title":"Analysis of the Prognostic Factors of Extensive Disease Small-Cell Lung Cancer Patients in Tokushima University Hospital.","authors":"H. Ogino, M. Hanibuchi, S. Kakiuchi, Atsuro Saijo, Toshifumi Tezuka, Yuko Toyoda, Makoto Tobiume, K. Otsuka, Satoshi Sakaguchi, H. Goto, K. Arisawa, Y. Nishioka","doi":"10.2152/jmi.63.286","DOIUrl":"https://doi.org/10.2152/jmi.63.286","url":null,"abstract":"BACKGROUND\u0000Small-cell lung cancer (SCLC) presents aggressive clinical behavior, and its prognosis is still poor. Previously, performance status (PS), or the existence of brain, bone, or liver metastasis were reported to be unfavorable prognostic factors. Given the recent progress of treatment modalities such as radiotherapy techniques and bone modifying agents, the prognostic factors might be different from previous findings. Therefore, we analyzed the prognostic factors of extensive disease SCLC (ED-SCLC) in recent years.\u0000\u0000\u0000METHODS\u0000ED-SCLC patients treated in Tokushima University Hospital between 2010 and 2016 were analyzed. Log-rank test and the Cox proportional hazards regression model was used in univariate and multivariate analysis, respectively.\u0000\u0000\u0000RESULTS\u0000Totally, 79 patients were analyzed. In the univariate analysis, age, PS, interstitial pneumonia (IP), liver metastasis, pleural dissemination, neutrophil counts, hypoalbuminemia, hypercalcemia and several liver and biliary enzymes were identified as poor prognostic factors. In the multivariate analysis, age, PS, IP, and liver and biliary enzymes were identified. Moreover, the PS in patients with liver metastasis was significantly worsened.\u0000\u0000\u0000CONCLUSIONS\u0000In this study, we newly demonstrated that IP was a significant poor prognostic factor of ED-SCLC. Although liver metastasis was not extracted in multivariate analysis, it may have an impact on the prognosis of ED-SCLC. J. Med. Invest. 63: 286-293, August, 2016.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"30 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123158628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

The risk of hemorrhage in stereotactic biopsy for brain tumors. 脑肿瘤立体定向活检出血的风险。

The journal of medical investigation : JMI Pub Date : 1900-01-01 DOI: 10.2152/jmi.66.314

Y. Mizobuchi, Kohei Nakajima, Toshitaka Fujihara, K. Matsuzaki, H. Mure, S. Nagahiro, Y. Takagi

{"title":"The risk of hemorrhage in stereotactic biopsy for brain tumors.","authors":"Y. Mizobuchi, Kohei Nakajima, Toshitaka Fujihara, K. Matsuzaki, H. Mure, S. Nagahiro, Y. Takagi","doi":"10.2152/jmi.66.314","DOIUrl":"https://doi.org/10.2152/jmi.66.314","url":null,"abstract":"Objective : One major complication associated with STB is intratumoral hematoma, which is also the most common cause of morbidity related to permanent paralysis and mortality in STB. The risk of perioperative hemorrhage is generally between 1% and 10%, but this could be an underestimation since it is not common for many neurosurgeons to perform CT scans after uncomplicated STBs. In this study, we describe the incidence of cerebral hemorrhage, including asymptomatic cerebral hemorrhage. Methods : We recently reviewed data on the diagnosis rate and occurrence of complications, including symptomatic and asymptomatic cerebral hemorrhage, in 80 patients who underwent STB at our facility between 2005 and 2014. Results : Histological diagnosis was established for 75 cases (93.8%), glioma was the most frequently encountered tumor. Symptomatic hemorrhage was observed in two cases (2.6%), with the symptoms subsiding within two days. The morbidity and mortality rate was 0%. However, asymptomatic hemorrhages were observed in 23 cases (28.8%). Conclusion : Stereotactic biopsy is a less invasive procedure for obtaining samples of brain tumors for diagnosis. The bleeding of the tissue-resection cavity that includes asymptomatic hemorrhage occurs at a constant rate. It is important to reduce the symptomatic bleeding associated with stereotactic biopsy. J. Med. Invest. 66 : 314-318, August, 2019.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"66 3.4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130672760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 29

Evaluation of the use of intraoperative real-time virtual sonography with sonazoid enhancement for detecting small liver metastatic lesions after chemotherapy in hepatic resection. 术中实时虚拟超声在肝切除化疗后小肝转移病灶检测中的应用评价。

The journal of medical investigation : JMI Pub Date : 1900-01-01 DOI: 10.2152/jmi.66.319

K. Araki, N. Harimoto, Ryo Muranushi, K. Hoshino, K. Hagiwara, Takahiro Yamanaka, Norihiro Ishii, Mariko Tsukagoshi, T. Igarashi, A. Watanabe, N. Kubo, K. Shirabe

{"title":"Evaluation of the use of intraoperative real-time virtual sonography with sonazoid enhancement for detecting small liver metastatic lesions after chemotherapy in hepatic resection.","authors":"K. Araki, N. Harimoto, Ryo Muranushi, K. Hoshino, K. Hagiwara, Takahiro Yamanaka, Norihiro Ishii, Mariko Tsukagoshi, T. Igarashi, A. Watanabe, N. Kubo, K. Shirabe","doi":"10.2152/jmi.66.319","DOIUrl":"https://doi.org/10.2152/jmi.66.319","url":null,"abstract":"Background : Systemic chemotherapy can drastically downsize metastatic liver tumors and these small liver lesions could sometimes be difficult for surgeons to detect during hepatectomy. We assessed the usefulness of intraoperative real-time virtual sonography (RVS) with contrast-enhanced ultrasonography (CEUS) using 'Sonazoid' contrast agent (RVS-CEUS). Methods : We performed the intraoperative RVS-CEUS technique on 10 tumor lesions in six cases, which were scheduled for hepatic resection of < 10 mm in diameter in our liver metastases series. These lesions were preoperatively diagnosed by contrast enhanced-computed tomography (CE-CT) or Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (EOB-MRI). We assessed the detectability of a tumor with RVS-CEUS during surgery and compared it with that of preoperative CE-CT or EOB-MRI. Results : Detectability of RVS-CEUS for 10 small lesions was 90% (n = 9/10) and that of other preoperative modalities were 50% (n = 5/10, CE-CT) and 100% (n = 10/10, EOB-MRI). Minimum tumor size detected was 3.0 mm in diameter, and maximum depth of detection with RVS-CEUS was 43.5 mm ; these results could be an advantage when compared with other intraoperative diagnostic modalities. Conclusion : Intraoperative RVS-CEUS was useful for detecting small metastatic liver lesions after chemotherapy and could be an effective intraoperative diagnostic technique for hepatic resection of a size < 10 mm. J. Med. Invest. 66 : 319-323, August, 2019.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"265 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132387360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

A case of Gross E esophageal atresia discovered following a unique clinical course. 一个特殊的临床过程后发现的食管闭锁病例。

The journal of medical investigation : JMI Pub Date : 1900-01-01 DOI: 10.2152/jmi.69.141

N. Yokota, H. Ishibashi, K. Suga, H. Mori, A. Kitamura, R. Nakagawa, M. Shimada

{"title":"A case of Gross E esophageal atresia discovered following a unique clinical course.","authors":"N. Yokota, H. Ishibashi, K. Suga, H. Mori, A. Kitamura, R. Nakagawa, M. Shimada","doi":"10.2152/jmi.69.141","DOIUrl":"https://doi.org/10.2152/jmi.69.141","url":null,"abstract":"The patient was a 15 months-old boy who had been diagnosed CHARGE syndrome, which is a multiple congenital anomaly syndrome caused by mutations in the CHD7 gene. Mechanical ventilation management was initiated 2 hours after birth for dysphagia and respiratory failure, and tracheotomy was performed 3 months after birth for dysphagia and failed extubation. He was repeatedly hospitalized due to pneuomoniae. Approximately 1 year after birth, the boy had two consecutive episodes of sudden ventilatory insufficiency while replacing the tracheotomy cannula. A bronchoscopic examination under general anesthesia revealed a tracheoesophageal fistula directly below the tracheostomy. The patient was diagnosed with Gross E esophageal atresia, and we speculated that the cannula migrated to the esophagus via the fistula during tracheostomy cannula replacement. Gross E esophageal atresia is a rare disease. Its diagnosis is often delayed, and it is discovered by recurrent pneumonia in many cases. A tracheoesophageal fistula may also be found in children with deformities of the respiratory system. Furthermore, tracheoesophageal fistulae are often found in the neck. Therefore, when sudden ventilatory insufficiency occurs in a child with a tracheostomy after replacing the tracheostomy cannula, caution must be exercised since the cannula may have migrated to the esophagus via a fistula. J. Med. Invest. 69 : 141-144, February, 2022.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124842773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0