The journal of medical investigation : JMI最新文献

Diaphragm-protective mechanical ventilation in acute respiratory failure. 急性呼吸衰竭的保护性膈膜机械通气。

The journal of medical investigation : JMI Pub Date : 2022-09-01 DOI: 10.3918/jsicm.29_510

T. Itagaki

{"title":"Diaphragm-protective mechanical ventilation in acute respiratory failure.","authors":"T. Itagaki","doi":"10.3918/jsicm.29_510","DOIUrl":"https://doi.org/10.3918/jsicm.29_510","url":null,"abstract":"Mechanical ventilation injures not only the lungs but also the diaphragm, resulting in dysfunction associated with poor outcomes. The chief mechanisms of ventilator-induced diaphragm dysfunction are : disuse atrophy due to insufficient contraction and excessive ventilatory support ; concentric load-induced injury due to excessive contraction and insufficient ventilatory support ; eccentric load-induced injury due to contraction during the expiratory phase ; and longitudinal atrophy caused by high positive end-expiratory pressure. To protect the diaphragm during mechanical ventilation, maintaining proper levels of diaphragm contraction is paramount ; thus, monitoring of respiratory effort and finely tuned ventilator settings are necessary. Furthermore, maintaining of synchronization between the patient and the ventilator is also important. As diaphragm dysfunction is more likely to occur in critically ill patients, diaphragm-protective mechanical ventilation strategies are essential to reduce the mortality rate of intensive care unit patients. This review outlines clinical evidence of ventilator-induced diaphragm dysfunction and its underlying mechanisms, and strategies to facilitate diaphragm-protective mechanical ventilation. J. Med. Invest. 69 : 165-172, August, 2022.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121360949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Impact of the Pre-operative Neutrophil-lymphocyte Ratio as the Predictive Marker of Post-operative Weight Loss and Improving Diabetes in Sleeve Gastrectomy. 术前中性粒细胞-淋巴细胞比值作为袖胃切除术术后体重减轻和糖尿病改善的预测指标的影响

The journal of medical investigation : JMI Pub Date : 2020-12-21 DOI: 10.21203/rs.3.rs-131065/v1

H. Kashihara, M. Shimada, K. Yoshikawa, Jun Higashijima, T. Tokunaga, M. Nishi, C. Takasu, T. Yoshimoto, Shohei Eto

{"title":"The Impact of the Pre-operative Neutrophil-lymphocyte Ratio as the Predictive Marker of Post-operative Weight Loss and Improving Diabetes in Sleeve Gastrectomy.","authors":"H. Kashihara, M. Shimada, K. Yoshikawa, Jun Higashijima, T. Tokunaga, M. Nishi, C. Takasu, T. Yoshimoto, Shohei Eto","doi":"10.21203/rs.3.rs-131065/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-131065/v1","url":null,"abstract":"PURPOSE\u0000The aim was to investigate the impact of the neutrophil-lymphocyte ratio (NLR) in sleeve gastrectomy (SG).\u0000\u0000\u0000METHODS\u000015 obese patients were enrolled in this study ; mean body weight (BW) 127.5kg ; mean body mass index (BMI) 46.7kg/m2. 10 of these were diabetics who underwent a SG. The impact of the pre-operative NLR on the percentage of excess weight loss (%EWL) and remission of diabetes 1 year post-operative were examined.\u0000\u0000\u0000RESULTS\u0000The %EWL at 1 year post-operative were 46.3%. Improvements were also evident in the diabetes at 1 year post-operative : complete remission (CR) 40%, partial remission (PR) 20% and Improve 40%. Comparing pre-operative NLR in %EWL<50% and ≧50% in 1 year post-operative, <50% was 2.64 and ≧50% was 2.03. The NLR in CR and PR was significantly lower than that in Improve.\u0000\u0000\u0000CONCLUSIONS\u0000The pre-operative NLR may be a predictive marker of weight loss and improving diabetes after SG. J. Med. Invest. 70 : 140-144, February, 2023.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130460316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of CKLF-like MARVEL transmembrane domain containing 6 (CMTM6) expression in gastric cancer. cklf样MARVEL跨膜结构域6 (CMTM6)表达在胃癌中的影响

The journal of medical investigation : JMI Pub Date : 2020-07-27 DOI: 10.21203/rs.3.rs-48504/v1

M. Nishi, M. Shimada, K. Yoshikawa, Jun Higashijima, T. Tokunaga, H. Kashihara, C. Takasu, Shohei Eto, T. Yoshimoto

{"title":"Impact of CKLF-like MARVEL transmembrane domain containing 6 (CMTM6) expression in gastric cancer.","authors":"M. Nishi, M. Shimada, K. Yoshikawa, Jun Higashijima, T. Tokunaga, H. Kashihara, C. Takasu, Shohei Eto, T. Yoshimoto","doi":"10.21203/rs.3.rs-48504/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-48504/v1","url":null,"abstract":"Background : CKLF-like MARVEL transmembrane domain containing 6 (CMTM6) is the master regulator of programmed cell death-ligand 1 (PD-L1). We aimed to clarify the significance of CMTM6 expression in gastric cancer (GC). Methods : A total of 105 patients who had undergone curative surgical resection for stage II / III GC at Tokushima University Hospital were included in this study. The expression of CMTM6 was examined by immunohistochemistry. Additionally, the relationship of each expression level to several prognostic factors was examined using univariate and multivariate analyses. Results : CMTM6 was not positively correlated with any of the factors examined. The overall survival (OS) rates were significantly poorer in the CMTM6 high-expression group than in the CMTM low-expression group (5-year OS : 57.2% vs. 79.2%, respectively ; p < 0.05). Disease-free survival (DFS) was significantly poorer in the CMTM high-expression group than in the CMTM6 low-expression group (5-year DFS : 52.8% vs. 72.4%, respectively ; p < 0.05). Multivariate analysis confirmed CMTM6 expression as an independent prognostic factor in DFS (p < 0.05). CMTM6 expression tended to be correlated with PD-L1 expression (p = 0.07). Conclusions : CMTM6 is associated with a poor prognosis and immunotolerance through PD-L1 in GC. J. Med. Invest. 68 : 362-367, August, 2021.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114735268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Regeneration of caudate lobe after living donor liver transplantation : Comparison with a surrogate model of left lobe graft. 活体肝移植后尾状叶的再生:与左叶移植替代模型的比较。

The journal of medical investigation : JMI Pub Date : 2020-06-12 DOI: 10.21203/rs.3.rs-34352/v1

Yu Saito, S. Imura, Y. Morine, T. Ikemoto, S. Yamada, M. Shimada

{"title":"Regeneration of caudate lobe after living donor liver transplantation : Comparison with a surrogate model of left lobe graft.","authors":"Yu Saito, S. Imura, Y. Morine, T. Ikemoto, S. Yamada, M. Shimada","doi":"10.21203/rs.3.rs-34352/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-34352/v1","url":null,"abstract":"Background : The aim of this study is to clarify the regeneration of the CL (caudate lobe) without any reconstructions of short hepatic veins (SHVr) after LDLT (living donor liver transplantation) and compare the regeneration of the CL after right hepatectomy (Rt. Hx), as the surrogate model of extended left lobe graft (Ex LLG) with complete SHVr. Methods : Eleven Ex LLGs with CL were included in this study. SHVr was not performed in all cases. The volumetry was performed before, one month and six months after LDLT. Seven patients who underwent Rt. Hx were also included in this study as the surrogate model. Results : In Ex LLGs with CL, the regeneration rate of the large CL (> 30 ml) was worse than that of small CL (< 30 ml). In the surrogate model, the regeneration rate of the CL was not worse than other segments. However, the regeneration rate of the large CL was also worse than that of small CL even in the presence of complete SHVr. Conclusions : The regeneration of the large CL was worse than that of the small CL regardless of the presence or absence of SHVr, indicating that SHVr in Ex LLG with CL might not be necessary. J. Med. Invest. 68 : 330-333, August, 2021.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125492862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Acute hypercalcemia and hypervitaminosis D associated with pulmonary tuberculosis in an elderly patient : A case report and review of the literature. 老年肺结核患者急性高钙血症和维生素D过多症:1例报告和文献复习。

The journal of medical investigation : JMI Pub Date : 2019-08-01 DOI: 10.2152/jmi.66.351

T. Wada, M. Hanibuchi, Atsuro Saijo

{"title":"Acute hypercalcemia and hypervitaminosis D associated with pulmonary tuberculosis in an elderly patient : A case report and review of the literature.","authors":"T. Wada, M. Hanibuchi, Atsuro Saijo","doi":"10.2152/jmi.66.351","DOIUrl":"https://doi.org/10.2152/jmi.66.351","url":null,"abstract":"An 80-year-old man was referred to our hospital for further examination of fever, cough and left pleural effusion. The laboratory findings showed acute inflammation, and the elevation of albumin-corrected serum calcium and 1,25-dihydroxyvitamin D3. A chest CT revealed centrilobular particulate opacity in the bilateral lung fields and left pleural effusion, indicating acute hypercalcemia and hypervitaminosis D associated with pulmonary tuberculosis. By the confirmation of Mycobacterium tuberculosis on polymerase chain reaction and cultures of the sputum and pleural effusion, a diagnosis of pulmonary tuberculosis was made. The patient successfully completed a 9-month course of the anti-tuberculosis treatment, and bilateral infiltrative shadows and left pleural effusion in chest X-ray disappeared. Symptoms progressively improved and serum level of albumin-corrected calcium and 1,25-dihydroxyvitamin D3 eventually normalized. While pulmonary tuberculosis is an infrequent cause of hypercalcemia, it should be considered in patients with hypercalcemia and elevated serum level of 1,25-dihydroxyvitamin D3. J. Med. Invest. 66 : 351-354, August, 2019.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133598621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Default mode network abnormalities in children with autism spectrum disorder detected by resting-state functional magnetic resonance imaging. 静息状态功能磁共振成像检测自闭症谱系障碍儿童默认模式网络异常。

The journal of medical investigation : JMI Pub Date : 2016-12-15 DOI: 10.2152/jmi.63.204

Y. Funakoshi, M. Harada, H. Otsuka, K. Mori, Hiromichi Ito, T. Iwanaga

{"title":"Default mode network abnormalities in children with autism spectrum disorder detected by resting-state functional magnetic resonance imaging.","authors":"Y. Funakoshi, M. Harada, H. Otsuka, K. Mori, Hiromichi Ito, T. Iwanaga","doi":"10.2152/jmi.63.204","DOIUrl":"https://doi.org/10.2152/jmi.63.204","url":null,"abstract":"PURPOSE\u0000The purpose of this study was to investigate changes in the functional connectivity of the default mode network (DMN) in normal aging and in children with autistic spectrum disorder (ASD) by using resting-state functional magnetic resonance imaging (rsfMRI) and independent component analysis.\u0000\u0000\u0000METHODS\u0000Thirty-one healthy controls (HC) in four age groups (1-3, 4-8, 20-29, and 50-59 years) and 14 childhood ASD cases (1-8 years of age) were examined by rsfMRI echo-planar imaging on a clinical 3-T MRI scanner. Imaging of all children (1-8 years) was conducted under sedation, while adults were scanned in the awake state with eyes closed.\u0000\u0000\u0000RESULTS\u0000The regions of DMN functional connectivity in the bilateral inferior parietal lobule and posterior cingulate cortex were smaller in HC children than in HC adults, and smaller in the ASD group than in the HC children.\u0000\u0000\u0000CONCLUSION\u0000It is possible to observe developmental and pathological changes in the DMN by rsfMRI. Reduced DMN functional connectivity in children may be a useful biomarker for ASD diagnosis. J. Med. Invest. 63: 204-208, August, 2016.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125115091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

The effect of dynamic stretching on hamstrings flexibility with respect to the spino-pelvic rhythm. 动态拉伸对腘绳肌柔韧性的影响。

The journal of medical investigation : JMI Pub Date : 2016-04-01 DOI: 10.2152/jmi.63.85

Kiyotaka Hasebe, Yu Okubo, K. Kaneoka, K. Takada, Daisuke Suzuki, K. Sairyo

{"title":"The effect of dynamic stretching on hamstrings flexibility with respect to the spino-pelvic rhythm.","authors":"Kiyotaka Hasebe, Yu Okubo, K. Kaneoka, K. Takada, Daisuke Suzuki, K. Sairyo","doi":"10.2152/jmi.63.85","DOIUrl":"https://doi.org/10.2152/jmi.63.85","url":null,"abstract":"OBJECTIVES\u0000To ascertain the dynamic stretch effects of flexibility of the hamstrings on lumbar spine and pelvic kinematics.\u0000\u0000\u0000BACKGROUND\u0000Tight hamstrings are positively correlated with low back pain. However, it is unclear how flexibility of the hamstrings affects spino-pelvic rhythm.\u0000\u0000\u0000METHODS\u0000Twelve healthy men participated in the study. The straight leg raising (SLR) angle, finger floor distance (FFD), and spino-pelvic rhythm was measured before and after the 6-week stretching protocol. The forward bending task was divided into 4 phases. The paired t-test was used to determine significant differences before and after the FFD, SLR angle, lumbar motion, and pelvic motion, and spino-pelvic rhythm in each phase (p<0.05).\u0000\u0000\u0000RESULTS\u0000After 6 weeks of stretching, significant improvements were seen in the FFD with maximum forward bending and in the SLR angle. Total pelvic rotation was also significantly increased in contrast to total lumbar flexion. A decreased spino-pelvic ratio was seen in the final phase.\u0000\u0000\u0000CONCLUSION\u0000Dynamic stretching could change the spino-pelvic rhythm to a pelvis-dominant motion, indicating that flexible hamstrings are important for preventing low back pain.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128014389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

Sp6 downregulation of follistatin gene expression in ameloblasts. Sp6下调成釉细胞卵泡抑素基因表达。

The journal of medical investigation : JMI Pub Date : 2008-02-01 DOI: 10.2152/JMI.55.303

Intan Ruspita, Keiko Miyoshi, T. Muto, K. Abe, Taigo Horiguchi, T. Noma

{"title":"Sp6 downregulation of follistatin gene expression in ameloblasts.","authors":"Intan Ruspita, Keiko Miyoshi, T. Muto, K. Abe, Taigo Horiguchi, T. Noma","doi":"10.2152/JMI.55.303","DOIUrl":"https://doi.org/10.2152/JMI.55.303","url":null,"abstract":"Sp6 is a member of the Sp family of transcription factors that regulate a wide range of cellular functions, such as cell growth and differentiation. Sp6, also called epiprofin, is specifically expressed in tooth germ, limb bud, and hair follicle, but there is little information on its function.To investigate the possible role of Sp6 in tooth development, first we established an Sp6-overproducing clone, CHA9, and analyzed the features of the cell, including cell proliferation and gene expression. The parental cells of CHA9 are the ameloblast-lineage G5 cells that we previously established from rat dental epithelia of lower incisor. Sp6 overproduction accelerated cell proliferation and induced the expression of ameloblastin mRNA, a marker of ameloblast differentiation. Second, we performed genome-wide screening of Sp6 target genes by microarray analysis. Out of a total 20,450 genes, 448 genes were up-regulated and 500 genes were down-regulated by Sp6. We found the expression of follistatin, a BMP antagonist, to be 22.4-fold lower in CHA9 than in control cells. Transfection of the Sp6-antisense construct into CHA9 cells restored follistatin expression back to equivalent levels seen in control cells, indicating that Sp6 regulates follistatin gene expression in ameloblasts. Our findings demonstrate that the follistatin gene is one of the Sp6 target genes in ameloblasts and suggest that Sp6 promotes amelogenesis through inhibition of follistatin gene expression.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131441604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 31

DNA adduct formation by 2-amino-3-methylimidazo [4,5-f] quinoline (IQ) in rat colon. 2-氨基-3-甲基咪唑喹啉[4,5-f]在大鼠结肠中形成DNA加合物。

The journal of medical investigation : JMI Pub Date : 2001-02-01 DOI: 10.11501/3180917

C. X. Lin, Y. Monden, A. Umemoto

引用次数: 1

Effect of amino acid mixtures on nasal allergic responses induced by toluene diisocyanate in mice. 氨基酸混合物对甲苯二异氰酸酯诱导小鼠鼻腔过敏反应的影响。

The journal of medical investigation : JMI Pub Date : 2000-08-01 DOI: 10.11501/3180850

T. H. Chen, K. Takeshita, K. Sakai, T. Komatsu, Y. Kishino, S. Yamamoto

{"title":"Effect of amino acid mixtures on nasal allergic responses induced by toluene diisocyanate in mice.","authors":"T. H. Chen, K. Takeshita, K. Sakai, T. Komatsu, Y. Kishino, S. Yamamoto","doi":"10.11501/3180850","DOIUrl":"https://doi.org/10.11501/3180850","url":null,"abstract":"We studied the effect of various amino acid mixtures on nasal allergy induced by the intranasal application of toluene diisocyanate (TDI) in mice. In Experiment 1 (Exp. 1), mice were fed a 25% casein, soy protein isolate (SPI), egg white protein (EW) or gluten diet. In Experiment 2 (Exp. 2), mice were fed a 25% amino acid mixture diets patterned after casein (AA-casein), SPI (AA-SPI), EW protein (AA-EW) or gluten (AA-gluten). In Experiment 3 3 (Exp. 3) we modified the glutamine/glutamic acid (Gln/Glu) concentrations in the amino acid mixtures. Mice were fed a 25% AA-SPI, low Gln/Glu AA-SPI (LG-AA-SPI), AA-EW or high Gln/Glu AA-EW (HG-AA-EW) diet. At the 5th week, mice were divided into sensitized (sen-) and non-sensitized (ns-) groups. The mice in sensitized groups were treated with two courses of intranasal application of toluene diisocyanate (TDI) in ethyl acetate for 5 consecutive days, separated by 9 days rest. The non-sensitized groups of mice were treated with a vehicle. Nine days after the second sensitization, all mice were provoked by TDI. Nasal responses and serum IgE concentration were studied. The findings of Exp. 1 showed that the sen-EW group exhibited a lower body weight gain, higher nasal symptom score and higher IgE concentration than the other sensitized groups. The findings dings of Exp. 2 showed that the sen-EW group had a lower body weight gain, higher nasal symptom score and higher IgE concentration than the other sensitized groups. In Exp. 3, the AA-EW group showed a higher total nasal score and IgE concentration than the HG-AA-EW group, however, the findings of LG-AA-SPI and AA-SPI were similar. These findings demonstrated that amino acid mixtures affect nasal allergy induced by the intranasal application of TDI in mice.","PeriodicalId":183570,"journal":{"name":"The journal of medical investigation : JMI","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125312502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1