术前中性粒细胞-淋巴细胞比值作为袖胃切除术术后体重减轻和糖尿病改善的预测指标的影响

The journal of medical investigation : JMI Pub Date : 2020-12-21 DOI:10.21203/rs.3.rs-131065/v1

H. Kashihara, M. Shimada, K. Yoshikawa, Jun Higashijima, T. Tokunaga, M. Nishi, C. Takasu, T. Yoshimoto, Shohei Eto

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引用次数: 0

摘要

目的探讨袖式胃切除术(SG)中中性粒细胞与淋巴细胞比值(NLR)的影响。方法15例肥胖患者入组;平均体重(BW) 127.5kg;平均体重指数(BMI) 46.7kg/m2。其中10人是接受了SG的糖尿病患者。研究了术前NLR对术后1年超重减重百分比(%EWL)和糖尿病缓解的影响。结果术后1年EWL为46.3%。术后1年糖尿病的改善也很明显:完全缓解(CR) 40%，部分缓解(PR) 20%，改善40%。比较术前EWL<50%和术后1年≧50%的NLR， <50%为2.64，≧50%为2.03。CR和PR组的NLR显著低于改善组。结论术前NLR可能是SG术后体重减轻和糖尿病改善的预测指标。中华医学杂志，2016,31(2):444 - 444。

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The Impact of the Pre-operative Neutrophil-lymphocyte Ratio as the Predictive Marker of Post-operative Weight Loss and Improving Diabetes in Sleeve Gastrectomy.

PURPOSE The aim was to investigate the impact of the neutrophil-lymphocyte ratio (NLR) in sleeve gastrectomy (SG). METHODS 15 obese patients were enrolled in this study ; mean body weight (BW) 127.5kg ; mean body mass index (BMI) 46.7kg/m2. 10 of these were diabetics who underwent a SG. The impact of the pre-operative NLR on the percentage of excess weight loss (%EWL) and remission of diabetes 1 year post-operative were examined. RESULTS The %EWL at 1 year post-operative were 46.3%. Improvements were also evident in the diabetes at 1 year post-operative : complete remission (CR) 40%, partial remission (PR) 20% and Improve 40%. Comparing pre-operative NLR in %EWL<50% and ≧50% in 1 year post-operative, <50% was 2.64 and ≧50% was 2.03. The NLR in CR and PR was significantly lower than that in Improve. CONCLUSIONS The pre-operative NLR may be a predictive marker of weight loss and improving diabetes after SG. J. Med. Invest. 70 : 140-144, February, 2023.

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The journal of medical investigation : JMI

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