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Measurement Techniques最新文献

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Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen. 鉴定内质网腔的 ERAD 依赖性脱胶子。
Measurement Techniques Pub Date : 2024-08-05 DOI: 10.1101/2023.06.21.546000
Rachel Sharninghausen, Jiwon Hwang, Devon D Dennison, Ryan D Baldridge
{"title":"Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen.","authors":"Rachel Sharninghausen, Jiwon Hwang, Devon D Dennison, Ryan D Baldridge","doi":"10.1101/2023.06.21.546000","DOIUrl":"10.1101/2023.06.21.546000","url":null,"abstract":"<p><p>Degrons are minimal protein features that are sufficient to target proteins for degradation. In most cases, degrons allow recognition by components of the cytosolic ubiquitin proteasome system. Currently, all of the identified degrons only function within the cytosol. Using <i>Saccharomyces cerevisiae</i>, we identified the first short linear sequences that function as degrons from the endoplasmic reticulum (ER) lumen. We show that when these degrons are transferred to proteins, they facilitate proteasomal degradation through the ERAD system. These degrons enable degradation of both luminal and integral membrane ER proteins, expanding the types of proteins that can be targeted for degradation in budding yeast and mammalian tissue culture. This discovery provides a framework to target proteins for degradation from the previously unreachable ER lumen and builds toward therapeutic approaches that exploit the highly-conserved ERAD system.</p>","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11326120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72929070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of operation models of complex technical systems 复杂技术系统运行模式分析
IF 0.5
Measurement Techniques Pub Date : 2023-12-08 DOI: 10.1007/s11018-023-02248-z
D. Ershov, A. V. Malakhov, A. V. Talalai, R. Khayrullin
{"title":"Analysis of operation models of complex technical systems","authors":"D. Ershov, A. V. Malakhov, A. V. Talalai, R. Khayrullin","doi":"10.1007/s11018-023-02248-z","DOIUrl":"https://doi.org/10.1007/s11018-023-02248-z","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"12 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138589576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The results of navigation spacecraft observations with asymmetry of the amplitude patterns of onboard antenna feed systems 机载天馈系统振幅模式不对称的导航航天器观测结果
IF 0.5
Measurement Techniques Pub Date : 2023-12-07 DOI: 10.1007/s11018-023-02253-2
A. Zavgorodnii, V. Voronov, I. V. Ryabov, A. A. Chigvincev
{"title":"The results of navigation spacecraft observations with asymmetry of the amplitude patterns of onboard antenna feed systems","authors":"A. Zavgorodnii, V. Voronov, I. V. Ryabov, A. A. Chigvincev","doi":"10.1007/s11018-023-02253-2","DOIUrl":"https://doi.org/10.1007/s11018-023-02253-2","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"59 26","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138592870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of the variable geometry of the flow switch nozzle exit on the metrological characteristics of a calibration unit with weighing devices 流量开关喷嘴出口的可变几何形状对带有称重装置的校准装置计量特性的影响
IF 0.5
Measurement Techniques Pub Date : 2023-12-07 DOI: 10.1007/s11018-023-02250-5
A. A. Korneev, A. Shchelchkov, R. A. Korneev
{"title":"Influence of the variable geometry of the flow switch nozzle exit on the metrological characteristics of a calibration unit with weighing devices","authors":"A. A. Korneev, A. Shchelchkov, R. A. Korneev","doi":"10.1007/s11018-023-02250-5","DOIUrl":"https://doi.org/10.1007/s11018-023-02250-5","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"4 8","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138592530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infrared visibility and infrared visibility range: practical significance and a measurement method 红外线能见度和红外线能见度范围：实际意义和测量方法
IF 0.5
Measurement Techniques Pub Date : 2023-12-07 DOI: 10.1007/s11018-023-02254-1
V. P. Khodunkov
{"title":"Infrared visibility and infrared visibility range: practical significance and a measurement method","authors":"V. P. Khodunkov","doi":"10.1007/s11018-023-02254-1","DOIUrl":"https://doi.org/10.1007/s11018-023-02254-1","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"60 17","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138592686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GET 200-2023 State Primary Standard of the transmitted (received) information (data) unit and the units of packet network parameters GET 200-2023 发送（接收）信息（数据）单位和分组网络参数单位的国家主要标准
IF 0.5
Measurement Techniques Pub Date : 2023-12-07 DOI: 10.1007/s11018-023-02247-0
A. Aprelev, V. S. Belyaev, Y. Suddenok, V. N. Shorin
{"title":"GET 200-2023 State Primary Standard of the transmitted (received) information (data) unit and the units of packet network parameters","authors":"A. Aprelev, V. S. Belyaev, Y. Suddenok, V. N. Shorin","doi":"10.1007/s11018-023-02247-0","DOIUrl":"https://doi.org/10.1007/s11018-023-02247-0","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"48 16","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138592071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strain gauge dynamometer for measuring the boundary layer friction force on the walls of wind tunnels 用于测量风洞壁上边界层摩擦力的应变计测力计
IF 0.5
Measurement Techniques Pub Date : 2023-12-07 DOI: 10.1007/s11018-023-02251-4
E. N. Anokhina, A. Gorbushin
{"title":"Strain gauge dynamometer for measuring the boundary layer friction force on the walls of wind tunnels","authors":"E. N. Anokhina, A. Gorbushin","doi":"10.1007/s11018-023-02251-4","DOIUrl":"https://doi.org/10.1007/s11018-023-02251-4","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"47 14","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138593088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of effective thickness of cemented steel layer 确定水泥钢层的有效厚度
IF 0.5
Measurement Techniques Pub Date : 2023-12-07 DOI: 10.1007/s11018-023-02255-0
S. G. Sandomirski, A. L. Val’ko, S. P. Rudenko
{"title":"Determination of effective thickness of cemented steel layer","authors":"S. G. Sandomirski, A. L. Val’ko, S. P. Rudenko","doi":"10.1007/s11018-023-02255-0","DOIUrl":"https://doi.org/10.1007/s11018-023-02255-0","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"8 3","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138589997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
State primary voltage standard of the fourth generation 第四代国家一次电压标准
IF 0.5
Measurement Techniques Pub Date : 2023-12-07 DOI: 10.1007/s11018-023-02246-1
A. S. Katkov, V. I. Shevtsov, Ju. A. Gromova
{"title":"State primary voltage standard of the fourth generation","authors":"A. S. Katkov, V. I. Shevtsov, Ju. A. Gromova","doi":"10.1007/s11018-023-02246-1","DOIUrl":"https://doi.org/10.1007/s11018-023-02246-1","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"23 6","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138594159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automated system for measuring electrophysical parameters of semiconductor structures 测量半导体结构电物理参数的自动化系统
IF 0.5
Measurement Techniques Pub Date : 2023-12-07 DOI: 10.1007/s11018-023-02252-3
E. Pecherskaya, O. V. Karpanin, D. Tuzova, M. A. Nelyutskov, V. V. Antipenko
{"title":"Automated system for measuring electrophysical parameters of semiconductor structures","authors":"E. Pecherskaya, O. V. Karpanin, D. Tuzova, M. A. Nelyutskov, V. V. Antipenko","doi":"10.1007/s11018-023-02252-3","DOIUrl":"https://doi.org/10.1007/s11018-023-02252-3","url":null,"abstract":"","PeriodicalId":18352,"journal":{"name":"Measurement Techniques","volume":"53 10","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138591930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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