Medical Journal of Australia最新文献

{"title":"Early-Onset Colorectal Cancer With Liver-Only Metastases: A Retrospective Cohort Study Integrating Prospectively Collected Real-World Clinical and Molecular Data From an Australian National Database (2009–2024) to Guide Treatment Planning","authors":"Savio G. Barreto, Christos S. Karapetis, Shahid Ullah, Matthew Burge, Susan Caird, Angus Campbell, Azim Jalali, Ross Jennens, Muhammad A. Khattak, Belinda Lee, Stephanie H. Lim, Shehara Mendis, Louise Nott, Timothy J. Price, Jeremy D. Shapiro, Jeanne Tie, Javier Torres, Colin Williams, Rachel Wong, Vanessa Wong, Peter Gibbs","doi":"10.5694/mja2.70266","DOIUrl":"https://doi.org/10.5694/mja2.70266","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To leverage the Treatment of Recurrent and Advanced Colorectal Cancer (TRACC) registry (an Australian cancer database) to explore the ideal timing and sequence of therapies and the factors influencing these decisions in colorectal cancer (CRC) patients with liver-only metastases to inform contemporary decision-making and future trials.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Type</h3>\u0000 \u0000 <p>Retrospective registry-based cohort study using the TRACC registry.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting and Participants</h3>\u0000 \u0000 <p>Consecutive patients with liver-only metastatic CRC enrolled in the TRACC registry.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main Outcome Measures</h3>\u0000 \u0000 <p>To explore cancer biology, intended treatment at presentation, actual treatment received and the resultant outcomes for early-onset CRC (EOCRC) (≤ 50 years) and late-onset CRC (LOCRC) (> 50 years) patients with liver-only metastases from a real-world perspective.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Between 14 January 2009 and 2 September 2024, 1691 patients with liver-only metastatic CRC were enrolled in TRACC. These included 276 EOCRC patients (16.3%) and 1415 LOCRC patients (83.7%). In the EOCRC subset, there were more females (48.2% vs. 34.5%, <i>p</i> < 0.001), less comorbidity (Charlson comorbidity index score 0, 90% vs. 59%, <i>p</i> < 0.001), more left-sided primaries (76.1% vs. 65.7%, <i>p</i> < 0.001), more synchronous disease (53.3% vs. 42.1%, <i>p</i> < 0.001) and <i>BRAF</i> V600E mutations (13.9% vs. 8.1%; <i>p</i> = 0.010). Overall, EOCRC patients had a longer median survival compared with LOCRC patients (3.20 vs. 2.38 years, <i>p</i> < 0.001). For the 662 patients (39.1%) undergoing liver resection, median survival was 5.99 years in EOCRC patients and 5.88 years in LOCRC patients. For all patients and for those undergoing resection, respectively, B-Raf proto-oncogene, serine/threonine kinase (<i>BRAF</i>) (hazard ratio, 1.97 [<i>p</i> < 0.001] and hazard ratio, 2.25 [<i>p</i> < 0.001]) and Kirsten rat sarcoma viral oncogene homologue (<i>KRAS</i>) mutations were associated with worse outcomes (hazard ratio, 1.29 [<i>p</i> < 0.001] and hazard ratio, 1.34 [<i>p</i> = 0.003]).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Differences in sex distribution, <i>BRAF</i> mutation rates, primary tumour site and over","PeriodicalId":18214,"journal":{"name":"Medical Journal of Australia","volume":"224 8","pages":""},"PeriodicalIF":6.8,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.5694/mja2.70266","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148784872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uneven Ground: Survival Differences Among Victorian Lung Cancer Patients by Location of Residence (2011–2023): A Retrospective Cohort Study","authors":"Evangeline Samuel, Eldho Paul, Mike Lloyd, Sanuki Tissera, Craig Underhill, Sagun Parakh, Phillip Parente, Inger Olesen, Javier Torres, Katharine See, Gavin M. Wright, David Langton, Thomas John, Matthew Conron, James Bartlett, Nicola Atkin, Nikolajs Zeps, Susan V. Harden, Wasek Faisal, John R. Zalcberg, Rob G. Stirling","doi":"10.5694/mja2.70268","DOIUrl":"https://doi.org/10.5694/mja2.70268","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Patients in regional and rural areas consistently experience poorer lung cancer survival rates compared with those in metropolitan centres, but the reasons remain unclear. This study examined survival differences in non-small cell lung cancer (NSCLC) across Victoria and identified key prognostic factors contributing to these differences.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Retrospective cohort study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting and Participants</h3>\u0000 \u0000 <p>NSCLC patients diagnosed between 1 July 2011 and 22 May 2023 identified from the Victorian Lung Cancer Registry (VLCR).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main Outcome Measures</h3>\u0000 \u0000 <p>Residential address and treatment institution were classified using the Modified Monash Model (MMM): Modified Monash (MM) category 1 (MM1) as metropolitan, MM2 as regional and MM3–MM7 as rural/remote. Demographic, socio-economic and cancer-specific factors were analysed as potential predictors of all-cause mortality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among 13,548 patients, 4244 (31%) lived in regional or rural/remote areas. Compared with metropolitan patients, these groups had higher smoking prevalence (metropolitan, 2848/9304 [31%] vs. regional, 366/1083 [34%] vs. rural, 1148/3161 [37%]) and were more likely to be Australian-born (metropolitan, 4919/9304 [53%] vs. regional, 873/1083 [81%] vs. rural, 2603/3161 [82%]; <i>p</i> < 0.001). Comorbidity burden was similar across groups (median, 1; interquartile range, 0.0–1.0; <i>p</i> = 0.19). Socio-economic disadvantage was more marked in regional and rural patients (median Index of Relative Socio-Economic Advantage and Disadvantage [IRSAD] deciles: metropolitan, 8.0 vs. regional, 5.0 vs. rural, 3.0; <i>p</i> < 0.001), and average travel times to treatment were longer (metropolitan, 0.4 vs. regional, 1.9 vs. rural, 2.8 h, respectively). Patients treated at regional institutions had poorer survival (hazard ratio [HR], 1.27; 95% confidence interval [CI], 1.19–1.35; <i>p</i> < 0.001). This difference persisted after adjustment for age, stage, performance status, smoking and comorbidities (HR, 1.11; 95% CI, 1.04–1.18; <i>p</i> = 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Regional, rural and remote patients with NSCLC face greater socio-economic disadvantage and travel burdens, and experie","PeriodicalId":18214,"journal":{"name":"Medical Journal of Australia","volume":"224 8","pages":""},"PeriodicalIF":6.8,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.5694/mja2.70268","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148783957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimating Eligibility for GLP-1 Receptor Agonists for Chronic Weight Management and Cardiovascular Disease in Australia: Cross-Sectional Analysis of National Health Survey Data","authors":"Jasmin Castrillon, Chris Schilling, Sharmala Thuraisingam, Michael W. Hii, Priya Sumithran, Peter F. Choong, Michelle M. Dowsey, Cade Shadbolt","doi":"10.5694/mja2.70253","DOIUrl":"10.5694/mja2.70253","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To estimate population-level eligibility for glucagon-like peptide-1 receptor agonist (GLP-1RA) medications among adults in Australia, according to Therapeutic Goods Administration-approved indications for chronic weight management and secondary prevention of cardiovascular disease in individuals with overweight or obesity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Type</h3>\u0000 \u0000 <p>Cross-sectional analysis of data from the Australian Bureau of Statistics 2022 National Health Survey.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting, Participants</h3>\u0000 \u0000 <p>Non-pregnant adults aged ≥ 18 years who were residents of Australia living in a private dwelling.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main Outcome Measures</h3>\u0000 \u0000 <p>Total number of adults eligible for GLP-1RA medications according to approved indications for chronic weight management and secondary prevention of cardiovascular disease in individuals with overweight or obesity, across subgroups defined by body mass index, weight-related comorbidities and/or sociodemographic factors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Overall, 39.7% (95% confidence interval [CI], 38.4%–41.0%) of adults were eligible for GLP-1RA use for chronic weight management, accounting for 7.8 million (95% CI, 7.6–8.1 million) individuals. Among those eligible, 2.9 million (95% CI, 2.7–3.1 million) adults had no weight-related comorbidities, 3.3 million (95% CI, 3.1–3.4 million) adults had one weight-related comorbidity and 1.7 million (95% CI, 1.6–1.8 million) adults had at least two weight-related comorbidities. The proportion of adults eligible under this indication varied across clinical and sociodemographic factors. Among those eligible under the chronic weight management indication, up to 338.9 thousand (95% CI, 271.3–406.5 thousand) adults also met the indication criteria for secondary prevention of cardiovascular disease.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>About 7.8 million Australian adults are eligible to access GLP-1RAs for chronic weight management, with up to 338.9 thousand adults also qualifying according to the indication for established cardiovascular disease. This study provides a valuable reference for policymakers to understand the number of adults in Australia who may access GLP-1RA medications based on approved indication criteria and under various coverage scenarios.</p>\u0000 ","PeriodicalId":18214,"journal":{"name":"Medical Journal of Australia","volume":"224 8","pages":""},"PeriodicalIF":6.8,"publicationDate":"2026-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.5694/mja2.70253","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148760553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Watchful Waiting Compared With Immediate Antibiotics for Urban Aboriginal and Torres Strait Islander Children With Uncomplicated Acute Otitis Media (WATCH): A Non-Inferiority Randomised Controlled Trial","authors":"Jennifer S. Reath, Hasantha Gunasekera, Sanja Lujic, Amanda J. Leach, Letitia Campbell, Robyn Walsh, Tim Usherwood, Geoffrey K. Spurling, Claudette A. Tyson, Deborah A. Askew, Kelvin Kong, Chelsea J. Watego, Peter Morris, Wendy Hu, Penelope A. Abbott","doi":"10.5694/mja2.70260","DOIUrl":"10.5694/mja2.70260","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Determine whether watchful waiting is non-inferior to immediate oral antibiotics for uncomplicated acute otitis media among urban Aboriginal and Torres Strait Islander children.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Type</h3>\u0000 \u0000 <p>Non-inferiority unblinded randomised controlled trial.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting and Participants</h3>\u0000 \u0000 <p>Eight Aboriginal Medical Services across three Australian states and territories between 25 August 2014 and 2 June 2023. Children (aged 1.5–16 years) with type B tympanograms and bulging tympanic membrane or acute pain/irritability were randomised by site and age (1.5–6 years and 7–16 years), with stratification using randomly allocated, permuted blocks of four and six in length.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main Outcome Measures</h3>\u0000 \u0000 <p>Watchful waiting compared with immediate oral antibiotics using modified intention-to-treat (using only available data) and per-protocol analyses of Day 7 clinical resolution with non-inferiority threshold set at 10 percentage points.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Children were randomly allocated to watchful waiting (134), six of whom were lost to follow-up or immediate antibiotics (129) with three lost to follow-up. Resolution occurred in 57/106 (53.8%) watchful waiting and 68/113 (60.2%) immediate antibiotic group of those with complete Day 7 data (−6.4 percentage points difference; 90% confidence interval [CI], −17.4 to 4.6) (modified intention-to-treat analysis). Per-protocol analysis similarly demonstrated reduced resolution in the watchful waiting group (49/97; 50.5%) compared with immediate antibiotics (67/112; 59.8%) with −9.3 percentage points difference (90% CI, −20.6 to 2.0). There was less Day 3 diarrhoea in watchful waiting (3/90; 3.3%) than in the immediate antibiotic group (13/93 [14.0%]; −10.7 percentage points difference; 95% CI, −18.6 to −2.7) but no other differences in vomiting, diarrhoea or rash (Days 3–14). Day 7 analgesia use was higher in the watchful waiting (53/107 [49.5%]) than immediate antibiotic group (37/116 [31.9%]; 17.6 percentage points difference; 95% CI, 4.9 to 30.1). There were no intervention-related severe adverse events or perforations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Although our results are numerically similar to those reported in other low-risk populations and no","PeriodicalId":18214,"journal":{"name":"Medical Journal of Australia","volume":"224 8","pages":""},"PeriodicalIF":6.8,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.5694/mja2.70260","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148726529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Case of Storage Mite Anaphylaxis in Infancy","authors":"Eliza Kluckow,&nbsp;Katie Frith","doi":"10.5694/mja2.70262","DOIUrl":"10.5694/mja2.70262","url":null,"abstract":"<div>\u0000 \u0000 <p>This is one of the first reported cases of storage mite anaphylaxis in Australia, occurring in an infant who had two episodes of severe anaphylaxis, triggered by previously tolerated foods. Both episodes occurred following extended periods of food storage, and in both instances, the child required two doses of intramuscular adrenaline. Skin prick testing was negative to implicated foods, but demonstrated sensitisation to house dust mite, and serum-specific IgE confirmed storage mite sensitisation. Clinician recognition of this condition is essential for timely diagnosis and implementation of preventive measures to reduce further episodes of life-threatening anaphylaxis in at-risk patients.</p>\u0000 </div>","PeriodicalId":18214,"journal":{"name":"Medical Journal of Australia","volume":"224 8","pages":""},"PeriodicalIF":6.8,"publicationDate":"2026-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148684967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Heat and Bushfire Smoke on Health System Utilisation in Australia","authors":"Hwan-Jin Yoon,&nbsp;Justin Boyle,&nbsp;Ibrahima Diouf,&nbsp;Rajiv Jayasena","doi":"10.5694/mja2.70261","DOIUrl":"10.5694/mja2.70261","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Objective&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;To characterise the associations of heat and bushfire smoke with health services utilisation and medication use at a national scale to support Australia's first National Climate Risk Assessment.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Design&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Cross-sectional, population study, covering health conditions with the highest burden of disease.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Setting and Participants&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;People in Australia accessing public health services between 2014 and 2020 for care related to cardiovascular, respiratory and mental health conditions.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Main Outcome Measures&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Relative risks of heat and bushfire smoke (particulate matter ≤ 2.5 μm in diameter [PM&lt;sub&gt;2.5&lt;/sub&gt;]) on health system utilisation and medication use, measured as emergency department (ED) presentations, hospital inpatient admissions, Medicare Benefits Schedule service claims in primary care and Pharmaceutical Benefits Scheme prescriptions dispensed. Relative risks (RRs) and 95% confidence intervals were estimated for short-term lags between exposure periods and health system usage.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Heat was most strongly associated with ED presentations, with a RR of 1.033 (95% CI, 1.023–1.043; &lt;i&gt;p&lt;/i&gt; &lt; 0.001) per degree temperature change for respiratory conditions and 1.023 (95% CI, 1.016–1.031; &lt;i&gt;p&lt;/i&gt; &lt; 0.001) for mental health conditions. PM&lt;sub&gt;2.5&lt;/sub&gt; at a 1-day lag had the highest association with hospital admissions, with a RR of 1.014 per 1 μg/m&lt;sup&gt;3&lt;/sup&gt; change in particulate density for both cardiovascular (&lt;i&gt;p&lt;/i&gt; = 0.001) and respiratory (&lt;i&gt;p&lt;/i&gt; = 0.002) conditions. Primary care visits for mental health conditions were strongly associated with levels of PM&lt;sub&gt;2.5&lt;/sub&gt; (RR, 1.049 [95% CI, 1.040–1.058]; &lt;i&gt;p&lt;/i&gt; &lt; 0.001) and with temperature (RR, 1.027 [95% CI, 1.014–1.039]; &lt;i&gt;p&lt;/i&gt; &lt; 0.001), while medication use increased across respiratory, cardiovascular and mental health categories in response to both exposures, with particulate matter showing stronger effects for cardiovascular, respiratory and mental health prescriptions. Mental health outcomes consistently showed vulnerability across all domains.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Heat was strongly associated with acute ED presentations, while particulate matter was stro","PeriodicalId":18214,"journal":{"name":"Medical Journal of Australia","volume":"224 8","pages":""},"PeriodicalIF":6.8,"publicationDate":"2026-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13444667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148679158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seven Vessel Spontaneous Coronary Artery Dissection and Concurrent Transient Global Amnesia After an Emotional Trigger","authors":"Michael J. Stewart,&nbsp;Tom R. Sutherland","doi":"10.5694/mja2.70257","DOIUrl":"10.5694/mja2.70257","url":null,"abstract":"","PeriodicalId":18214,"journal":{"name":"Medical Journal of Australia","volume":"224 8","pages":""},"PeriodicalIF":6.8,"publicationDate":"2026-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148679194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seven Vessel Spontaneous Coronary Artery Dissection and Concurrent Transient Global Amnesia After an Emotional Trigger","authors":"Virginia Barbour","doi":"10.5694/mja2.70258","DOIUrl":"10.5694/mja2.70258","url":null,"abstract":"","PeriodicalId":18214,"journal":{"name":"Medical Journal of Australia","volume":"224 8","pages":""},"PeriodicalIF":6.8,"publicationDate":"2026-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148679156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Getting on the Same Page: Why Australia Needs a National Maternity Early Warning System (MEWS) Chart","authors":"Briony A. Cutts,&nbsp;Lucy Bowyer,&nbsp;Nisha Khot,&nbsp;Sandra Lowe,&nbsp;Stefan C. Kane","doi":"10.5694/mja2.70256","DOIUrl":"10.5694/mja2.70256","url":null,"abstract":"<p>Observation charts are used to record and prompt responses for acutely deteriorating patients. Compared to non-pregnant observation charts, maternity charts reflect physiological changes of pregnancy and the immediate postpartum period. Maternity observation charts differ across Australian states and territories, resulting in a lack of comparable data, standardised care and optimisation of streamlining education and training. To improve maternity care across the country, we propose that the Australian Commission on Safety and Quality in Health Care, in the upcoming third edition of the <i>National Safety and Quality Health Service Standards</i>, review Standard 8 (recognising and responding to the acutely deteriorating patients) to generate a national Maternity Early Warning System (MEWS) Chart.</p>","PeriodicalId":18214,"journal":{"name":"Medical Journal of Australia","volume":"224 8","pages":""},"PeriodicalIF":6.8,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148673716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unshrouding Social Determinants: A Case for Standardised Data in Australia's Health Information Ecosystem","authors":"Christopher Ryan,&nbsp;Christine T. Shiner,&nbsp;Rebecca J. Harris,&nbsp;Carrie Lethborg,&nbsp;Vijaya Sundararajan","doi":"10.5694/mja2.70259","DOIUrl":"10.5694/mja2.70259","url":null,"abstract":"<p>Australia's health information system captures clinical and administrative data with precision but overlooks social determinants of health (SDoH), such as housing and education. This deficiency limits predictive accuracy of clinical and economic models and perpetuates health inequities. Despite significant investment in digital health reforms, Australia's current strategies for data interoperability lack SDoH standards. Drawing on international benchmarks, Australia should pursue a national framework to integrate standardised SDoH measures into electronic health records. Collaborative adoption via a phased approach focused on data sovereignty, interoperability and ethical AI governance has the potential to transform Australia's healthcare into a more person-centred, equitable system.</p>","PeriodicalId":18214,"journal":{"name":"Medical Journal of Australia","volume":"224 8","pages":""},"PeriodicalIF":6.8,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148673721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}