Liver最新文献_第6页

Glafenine-associated hepatic injury: 38 or 5 cases? glafenine相关性肝损伤:38例还是5例?

Liver Pub Date : 1987-02-01 DOI: 10.1111/j.1600-0676.1987.tb00316.x

G Danan, J P Benhamou

引用次数: 1

Ketoconazole-induced hepatitis: a case with a definite cause-effect relationship. 酮康唑致肝炎:1例有明确因果关系的病例。

Liver Pub Date : 1987-02-01 DOI: 10.1111/j.1600-0676.1987.tb00311.x

G van Parys, C Evenepoel, B van Damme, V J Desmet

引用次数: 13

Congenital intrahepatic cholestasis with pigment deposits and abnormal bile acid metabolism. A variant of Dubin-Johnson's syndrome? 先天性肝内胆汁淤积症伴色素沉积及胆汁酸代谢异常。杜宾-约翰逊综合症的变种?

Liver Pub Date : 1987-02-01 DOI: 10.1111/j.1600-0676.1987.tb00312.x

A Bremmelgaard, L Ranek, E Hage, N Tygstrup

引用次数: 3

Biliary lipid composition in patients with non-cirrhotic portal fibrosis--a comparison with compensated cirrhosis of the liver. 非肝硬化门脉纤维化患者的胆脂组成——与代偿性肝硬化的比较

Liver Pub Date : 1987-02-01 DOI: 10.1111/j.1600-0676.1987.tb00313.x

S K Sarin, K Lal, G Sachdeva, R Nanda, R K Tandon

引用次数: 6

Portal tract lipogranulomas in liver biopsies. 肝活检显示门静脉脂肪肉芽肿。

Liver Pub Date : 1987-02-01 DOI: 10.1111/j.1600-0676.1987.tb00309.x

J K Delladetsima, T Horn, H Poulsen

引用次数: 15

Relationship of histologic grade of hepatocellular carcinoma (HCC) to tumor size, and demonstration of tumor cells of multiple different grades in single small HCC. 肝细胞癌(HCC)的组织学分级与肿瘤大小的关系，以及单个小肝癌中多个不同级别肿瘤细胞的表现。

Liver Pub Date : 1987-02-01 DOI: 10.1111/j.1600-0676.1987.tb00310.x

K Kenmochi, S Sugihara, M Kojiro

{"title":"Relationship of histologic grade of hepatocellular carcinoma (HCC) to tumor size, and demonstration of tumor cells of multiple different grades in single small HCC.","authors":"K Kenmochi, S Sugihara, M Kojiro","doi":"10.1111/j.1600-0676.1987.tb00310.x","DOIUrl":"https://doi.org/10.1111/j.1600-0676.1987.tb00310.x","url":null,"abstract":"The histologic features of 65 surgically resected cases of hepatocellular carcinoma (HCC) were studied, and the cellular differentiation was graded from I to IV according to Edmondson-Steiner's classification. HCC cells of 2 or more grades were seen in 31 (47.7%) of the 65 cases. There was no significant difference in the proportion of HCC composed of tumor cells of more than one histologic grade between HCCs with association with liver cirrhosis and without cirrhosis. Among these 31 cases, extremely well-differentiated HCC, corresponding to Edmondson-Steiner's grade I carcinoma, was found in 9 of 11 tumors smaller than 3 cm in diameter, but it was not seen in 20 tumors larger than 3 cm in diameter. In the 34 HCCs with a uniform histologic pattern, all of two minute tumors smaller than 1 cm in diameter consisted of extremely well-differentiated HCC, but there were no cases consisting of extremely well-differentiated HCC in tumors larger than 2 cm in diameter. Taken together, these findings suggest that HCCs originate as relatively well-differentiated tumors, which may be difficult to distinguish from adenomatous regenerative nodules, and become progressively less differentiated at a later stage of their development.","PeriodicalId":18183,"journal":{"name":"Liver","volume":"7 1","pages":"18-26"},"PeriodicalIF":0.0,"publicationDate":"1987-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1600-0676.1987.tb00310.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14166092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 218

Spontaneous and antibody-dependent cellular immune reactions to ethanol-altered hepatoma cells. 对乙醇改变的肝癌细胞的自发和抗体依赖性细胞免疫反应。

Liver Pub Date : 1987-02-01 DOI: 10.1111/j.1600-0676.1987.tb00315.x

T Poralla, T H Hütteroth, A Knuth, M Staritz, H P Dienes, K H Meyer zum Büschenfelde

引用次数: 3

Steroids in chronic B-hepatitis. A randomized, double-blind, multinational trial on the effect of low-dose, long-term treatment on survival. A trial group of the European Association for the Study of the Liver. 类固醇治疗慢性乙型肝炎。一项随机、双盲、多国试验，研究低剂量、长期治疗对生存率的影响。欧洲肝脏研究协会的一个试验组。

Liver Pub Date : 1986-08-01

引用次数: 0

Glafenine-associated hepatic injury. Analysis of 38 cases and review of the literature. glafenine相关的肝损伤。38例病例分析及文献复习。

Liver Pub Date : 1986-04-01

B H Stricker, A P Blok, F B Bronkhorst

引用次数: 0

Alpha-1-antitrypsin (AAT) and its stimulation in the liver of PiMZ phenotype individuals. A "recruitment-secretory block" ("R-SB") phenomenon. α -1抗胰蛋白酶(AAT)及其在PiMZ表型个体肝脏中的刺激作用。“招聘-秘书阻碍”(R-SB)现象。

Liver Pub Date : 1984-10-01

F Callea, J Fevery, G Massi, C Lievens, J de Groote, V J Desmet

{"title":"Alpha-1-antitrypsin (AAT) and its stimulation in the liver of PiMZ phenotype individuals. A \"recruitment-secretory block\" (\"R-SB\") phenomenon.","authors":"F Callea, J Fevery, G Massi, C Lievens, J de Groote, V J Desmet","doi":"","DOIUrl":"","url":null,"abstract":"PiMZ individuals in conditions of clinical stimulation show a peculiar immunohistochemical staining pattern for alpha-1-antitrypsin (AAT) in the liver: 1) the positivity involves large zones of parenchyma (up to 100% of hepatocytes); 2) in zone 2 and zone 3 hepatocytes the positivity appears in the form of crescents or rectilinear arrays along the sinusoids. This new pattern is designated type II, in contrast to type I which occurs in periportal hepatocytes in the form of inclusions spread over the whole cytoplasm. This peculiar staining pattern is associated with serum elevation of AAT and is considered to be an expression of liver reactivity. Type II positivity marks the hepatocytes which are newly recruited for the synthesis of AAT; owing to its defective export, the Z AAT is retained within the cell and detectable by immunohistochemistry. Thus this staining pattern is an expression of both recruitment for synthesis and block of secretion (\"Recruitment-Secretory Block\" \"R-SB\" phenomenon). In PiMZ individuals, the secretory block affects selectively and exclusively the Z fraction of AAT. At the EM level the vast majority of the retained protein is found in the RER, which represents the major and the earliest site of storage. Viewed in the framework of present knowledge of glycoprotein biosynthesis, the results of this study shed further light on the nature and cellular site of the Z AAT defect.","PeriodicalId":18183,"journal":{"name":"Liver","volume":"4 5","pages":"325-37"},"PeriodicalIF":0.0,"publicationDate":"1984-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17395409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0