Magnetic Resonance in Chemistry最新文献

{"title":"The Effect of Homogeneous and Inhomogeneous Electric Fields on NMR Properties of Imidazole and Pyrrole Under","authors":"R. M. Gester,&nbsp;G. F. Quinteiro Rosen,&nbsp;A. R. Cunha,&nbsp;V. Manzoni,&nbsp;G. I. Pagola,&nbsp;P. F. Provasi","doi":"10.1002/mrc.70118","DOIUrl":"10.1002/mrc.70118","url":null,"abstract":"<div>\u0000 \u0000 <p>In this study, we examine the influence of homogeneous and highly inhomogeneous electric fields (HIEFs) on NMR parameters such as isotropic spin–spin couplings and nuclear magnetic shieldings. The model compounds imidazole and pyrrole were chosen because of their distinct symmetries with respect to the applied fields. Calculations were performed at the CAM-B3LYP and second-order polarization propagator approximation (SOPPA) levels using the aug-cc-pVTZ-J basis set. The results show that the influence of the external HIEF is comparable in magnitude with that produced by solvation in water. The coupling constants exhibit angular dependence that partially resembles Karplus-type relationships, with a slight asymmetry, with nitrogen nuclei showing the most pronounced responses. One-bond couplings are mainly governed by their Fermi contact contributions, so that the isotropic coupling is almost indistinguishable from the Fermi contact term. In contrast, the two-bond couplings display a clear separation between the Fermi contact and the isotropic values, influenced by paramagnetic spin–orbit or spin–dipolar contributions. The nuclear shieldings, in turn, exhibit a more harmonic dependence, following the variations of the applied field.</p>\u0000 </div>","PeriodicalId":18142,"journal":{"name":"Magnetic Resonance in Chemistry","volume":"64 9","pages":"768-784"},"PeriodicalIF":2.1,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147964174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pure Gaussian Apodisation Reduces Integral Crosstalk Sensitivity in Quantitative NMR","authors":"A. Flook,&nbsp;C. S. Raman,&nbsp;G. C. Lloyd-Jones","doi":"10.1002/mrc.70113","DOIUrl":"10.1002/mrc.70113","url":null,"abstract":"<p>Exponential apodisation is routinely applied in quantitative NMR measurements to increase signal-to-noise ratio (SNR) and integral precision, with a peak broadening effect. However, apodisation suitability is typically evaluated using SNR and peak broadening metrics and does not consider how apodisation alters peak area distribution. Here, we assess how exponential apodisation extends peak wings and relocates area away from the peak centre. This necessitates larger integral regions to account for the same area, increasing the potential for peak overlap and introducing variability in the trueness of the measurement. As an alternative, we show that a pure Gaussian apodisation can deliver comparable SNR improvements to the common exponential apodisation when tuned to a matched broadening criterion, reducing overlap of peak wings and improving robustness of finite-window integration. As a result, the narrower line width prior to apodisation can be used to guide appropriate integral region choice. Overall, a pure Gaussian apodisation is demonstrated to be a robust alternative to exponential apodisation, especially in conjunction with complex 1D NMR spectra.</p>","PeriodicalId":18142,"journal":{"name":"Magnetic Resonance in Chemistry","volume":"64 9","pages":"748-757"},"PeriodicalIF":2.1,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mrc.70113","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enabling Quantitative Benchtop 13C NMR Spectroscopy in Fast Continuous Flow","authors":"Sarah Mross,&nbsp;Hans Hasse,&nbsp;Kerstin Münnemann","doi":"10.1002/mrc.70119","DOIUrl":"10.1002/mrc.70119","url":null,"abstract":"&lt;p&gt;Continuous-flow benchtop NMR spectroscopy is highly attractive for quantitative reaction and process monitoring. Although \u0000&lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;msup&gt;\u0000 &lt;mrow&gt;&lt;/mrow&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mn&gt;1&lt;/mn&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;/msup&gt;&lt;/math&gt;H NMR spectroscopy is widely used, signal overlap frequently compromises quantitative analysis. In principle, this limitation can be addressed by \u0000&lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;msup&gt;\u0000 &lt;mrow&gt;&lt;/mrow&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mn&gt;13&lt;/mn&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;/msup&gt;&lt;/math&gt;C NMR spectroscopy; however, its application is restricted by the inherently low sensitivity of \u0000&lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;msup&gt;\u0000 &lt;mrow&gt;&lt;/mrow&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mn&gt;13&lt;/mn&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;/msup&gt;&lt;/math&gt;C nuclei. This limitation is further aggravated by insufficient polarization buildup in benchtop NMR spectroscopy in fast continuous flow, as the compact design provides only short residence times in the premagnetization zone. We demonstrate here that the latter limitation can be overcome by paramagnetic relaxation enhancement (PRE). Furthermore, we demonstrate that applying PRE is particularly effective when combined with a method that enhances weak \u0000&lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;msup&gt;\u0000 &lt;mrow&gt;&lt;/mrow&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mn&gt;13&lt;/mn&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;/msup&gt;&lt;/math&gt;C polarization, such as \u0000&lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;msup&gt;\u0000 &lt;mrow&gt;&lt;/mrow&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mn&gt;1&lt;/mn&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;/msup&gt;&lt;/math&gt;H to \u0000&lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;msup&gt;\u0000 &lt;mrow&gt;&lt;/mrow&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mn&gt;13&lt;/mn&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;/msup&gt;&lt;/math&gt;C polarization transfer. For this, we used PENDANT. We report the first application of PRE (with and without PENDANT) for quantitative analysis of mixtures with continuous-flow \u0000&lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;msup&gt;\u0000 &lt;mrow&gt;&lt;/mrow&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mn&gt;13&lt;/mn&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;/msup&gt;&lt;/math&gt;C benchtop NMR spectroscopy. Experiments were carried out for common solvents (acetonitrile, 1,4-dioxane, and ethanol) as well as binary and ternary mixtures of these solvents over a wide range of flow rates. The results demonstrate that PRE, especially when combined with PENDANT, enables robust quantitative analysis with \u0000&lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;msup&gt;\u0000 &lt;mrow&gt;&lt;/mrow&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mn&gt;13&lt;/mn&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;/msup&gt;&lt;/math&gt;C NMR spectroscopy even at high flow rates, significantly expanding the applicability of benchtop NMR instruments for quantitative reaction and pr","PeriodicalId":18142,"journal":{"name":"Magnetic Resonance in Chemistry","volume":"64 9","pages":"758-767"},"PeriodicalIF":2.1,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mrc.70119","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147941894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Field-Cycling NMR Relaxometry in Tire Elastomer Science","authors":"Francesca Nardelli,&nbsp;Michele Pierigé,&nbsp;Elisa Carignani,&nbsp;Marco Geppi,&nbsp;Francesca Martini,&nbsp;Lucia Calucci","doi":"10.1002/mrc.70117","DOIUrl":"10.1002/mrc.70117","url":null,"abstract":"<p>Field-cycling (FC) NMR relaxometry is an ideal tool to investigate multiscale polymer dynamics since it can give access to longitudinal relaxation rates (<i>R</i>₁(<i>ω</i>)) over a broad Larmor frequency range, which can be further extended by employing the frequency–temperature superposition principle. Applications of FC NMR on elastomers of interest for tire industry (i.e., <i>cis</i>-1,4-polyisoprene, <i>cis</i>-1,4-polybutadiene, and co-poly [styrene-butadiene]), aimed to obtain information on segmental and polymer dynamics over different regimes as a function of chain length in polymer melts and in dependence on cross-linking degree and addition of fillers or additives in rubbers, are here reviewed for the first time. After a brief presentation of theoretical tools used in data analysis, studies on polymer melts at variable temperature are reported allowing theories for polymer dynamics, such as tube reptation and renormalized Rouse models, to be tested in the entanglement regime through characteristic dependences of <i>R</i>₁(<i>ω</i>) on Larmor frequency. Then, studies on rubbers and elastomer compounds are illustrated, highlighting the effects of curing conditions (i.e., temperature, concentration of sulfur and accelerant), and the presence of reinforcing fillers and additives (e.g., tackifying resins) on segmental dynamics, related to macroscopic properties as glass transition temperature, and on collective polymer dynamics. Issues connected with the application of FC NMR relaxometry to polymeric systems with increasing structural and compositional complexity are critically discussed.</p>","PeriodicalId":18142,"journal":{"name":"Magnetic Resonance in Chemistry","volume":"64 9","pages":"801-820"},"PeriodicalIF":2.1,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mrc.70117","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Synergistic Approach to the Structural Characterization of 2-(Morpholin-4-yl)quinoline-3-carbaldehyde by Solution and Solid-State NMR Spectroscopy, Supported by Single-Crystal X-Ray Diffraction and DFT Calculations.","authors":"Srinivasa, Nivedita R Desai, P A Suchetan, Swamy Sreenivasa, Tadimety Madhu Chakrapani Rao, Shivakumar, Udayakumar Dalimba, D B Aruna Kumar","doi":"10.1002/mrc.70136","DOIUrl":"https://doi.org/10.1002/mrc.70136","url":null,"abstract":"<p><p>Heterocyclic building blocks incorporating quinoline and morpholine units are central to the synthesis of a wide range of biologically active molecules, where conformational preferences and solid-state organization can directly influence the reactivity and functional performance. In this study, the molecular structure of 2-(morpholin-4-yl)quinoline-3-carbaldehyde (abbreviated as MQ3CA), a key intermediate for quinoline-, morpholine-, and piperazine-based drug scaffolds, is examined using a synergistic combination of solution and solid-state NMR spectroscopy, complemented by single-crystal X-ray diffraction (SC-XRD) and density functional theory (DFT) calculations. Complete resonance assignments, including chemical shifts, scalar coupling constants, and through-bond and through-space correlations, were achieved using 2D J-resolved, COSY, NOESY, HSQC, and HMBC experiments, enabling an unambiguous description of molecular connectivity and conformation in solution. Solid-state ¹³C CPMAS-TOSS and two-dimensional ¹H-¹³C HETCOR NMR measurements provided atomic-level insight into the solid-state organization of MQ3CA. The observed differences between the solid- and solution-state ¹³C chemical shifts indicate the influence of crystal packing and weak intermolecular interactions, consistent with the crystallographic analysis. PXRD analysis further confirmed the absence of polymorphic phases in the investigated sample. The SC-XRD information supports that the morpholine ring adopts a chair conformation with the quinoline ring positioned in the equatorial plane, whereas C-H···O hydrogen bonds and π···π interactions dominate the crystal packing. DFT-derived electronic descriptors further support the experimentally observed structural stability. This work demonstrates the effectiveness of integrated magnetic resonance approaches for resolving structure-packing relationships in pharmaceutically relevant intermediates.</p>","PeriodicalId":18142,"journal":{"name":"Magnetic Resonance in Chemistry","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148630849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of ERETIC-Based ¹H-NMR for the Simultaneous Quantification of Cannabinoids in Complex Cannabis sativa Extracts.","authors":"Rocío Figueroa, Federico Arrighi, Mauricio Cattaneo, Miguel Gilabert","doi":"10.1002/mrc.70135","DOIUrl":"https://doi.org/10.1002/mrc.70135","url":null,"abstract":"<p><p>Chromatographic methods for cannabinoid analysis currently face limitations, including lengthy procedures, artifact formation, and reliance on reference standards. This study establishes a robust quantitative ¹H-NMR methodology for simultaneous analysis of acidic and neutral cannabinoids (THCA, CBDA, Δ⁹-THC, CBD, and CBN) in Cannabis sativa extracts. Two validated strategies, internal standard (butylated hydroxytoluene [BHT]) and ERETIC calibration, were compared, with diagnostic signals identified in interference-free spectral regions. The method demonstrated high precision (RSD < 5%), accuracy (recoveries 97%-102%), and low detection limits (MLOD 0.07 mg/mL). ERETIC outperformed traditional calibration by eliminating physical standards while maintaining equivalency. Successful chemotypic classification (THC:CBD ratios) confirmed practical applicability. The ERETIC-based NMR approach provides a rapid and reproducible alternative for comprehensive cannabinoid quantification without derivatization.</p>","PeriodicalId":18142,"journal":{"name":"Magnetic Resonance in Chemistry","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148561940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"nh-PHIP Hyperpolarization for Biological Mixture Analysis.","authors":"Kerti Ausmees, Indrek Reile","doi":"10.1002/mrc.70133","DOIUrl":"https://doi.org/10.1002/mrc.70133","url":null,"abstract":"<p><p>Non-hydrogenative parahydrogen-induced polarization (nh-PHIP) is an NMR sensitivity enhancement technique that is particularly suitable for studying biological samples. It can provide up to three orders of magnitude signal enhancements for a continuously expanding range of valuable analyte classes like drugs, vitamins, nucleobases, nucleosides and nucleotides, amino acids, oligopeptides, etc. The strengths of nh-PHIP lay in its modest instrumental requirements over a standard commercial NMR spectrometer, its simple operating workflow that is similar to traditional NMR spectroscopy, and its proven capability to offer quantitative information from below the sensitivity barrier of regular NMR. This tutorial will give an overview of the background, the principles, and the present application scope of nh-PHIP hyperpolarization. We provide guidelines for setting up an nh-PHIP experiment, from sample preparation to optimizing the hyperpolarization for a particular analyte class. This includes the description of the basic experimental setup and outlining the considerations for method development. An overview of different available nh-PHIP pulse sequences will be given to assist the reader in implementing nh-PHIP.</p>","PeriodicalId":18142,"journal":{"name":"Magnetic Resonance in Chemistry","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148520402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differentiation of Plant and Animal-Derived Cholesterol Using irm-13C NMR and IRMS","authors":"Anika M. Singh,&nbsp;Subir Chakraborty,&nbsp;Remington X. Poulin,&nbsp;R. Thomas Williamson","doi":"10.1002/mrc.70112","DOIUrl":"10.1002/mrc.70112","url":null,"abstract":"<p>In the European Union, animal products for human consumption are regulated as products of animal origin (POAO), while those not intended for human consumption are considered animal by-products (ABPs). Both POAO and ABP are subject to strict regulations to ensure animal and public health, and they are controlled through various EU directives and regulations. Consumer demand for plant-derived cosmetics, botanicals, and nutraceuticals has also increased sharply over the past decade. Ensuring the origin of ingredients, starting materials, and excipients used in these complex consumer products can be challenging, even when certified reference standards are available. Herein, we report a reliable approach for identifying the origin of cholesterol, a common ingredient in cosmetics and beauty products, using irm-¹³C NMR and IRMS to differentiate plant versus animal-derived cholesterol. Further, we show that we can also discriminate semi-synthetic cholesterol from plant and animal-derived varieties.</p>","PeriodicalId":18142,"journal":{"name":"Magnetic Resonance in Chemistry","volume":"64 8","pages":"701-708"},"PeriodicalIF":2.1,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mrc.70112","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facilitating Total Lineshape Analysis of Complex NMR Spectra With FOMA and ANATOLIA-X Multiplet Fitting Tools, Exemplified by the Vinyl Norbornene Case","authors":"A. I. Nichugovskiy,&nbsp;V. V. Zamalyutin,&nbsp;V. R. Flid,&nbsp;D. A. Cheshkov","doi":"10.1002/mrc.70111","DOIUrl":"10.1002/mrc.70111","url":null,"abstract":"<div>\u0000 \u0000 <p>To facilitate the total lineshape analysis of the NMR spectra of complex multispin systems, which is challenging for existing NMR software, two novel tools, first-order multiplet analyzer (FOMA) and ANATOLIA-X, are introduced. FOMA is a first-order multiplet analyzer designed for total lineshape fitting of a single complex first-order multiplet, while ANATOLIA-X is a modified version of our previous program ANATOLIA with X-factorization of the spin Hamiltonian, allowing for the analysis of individual strongly coupled multiplets. These tools are targeted at the analysis of subspectra to generate initial parameter sets for the total lineshape fitting procedure. The efficiency of FOMA is demonstrated through its successful application to the analysis of complex multiplets. Both tools were employed in a total lineshape analysis of the high-resolution NMR spectra of vinylnorbornene, enabling the precise determination of absolute values of all proton–proton spin–spin coupling constants.</p>\u0000 </div>","PeriodicalId":18142,"journal":{"name":"Magnetic Resonance in Chemistry","volume":"64 8","pages":"690-700"},"PeriodicalIF":2.1,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distinguishing Hydrogen Bonding in Structurally Similar Pharmaceutical Compounds With 1H-14N HMQC MAS NMR at 100 kHz","authors":"Chaithanya Hareendran,&nbsp;T. G. Ajithkumar","doi":"10.1002/mrc.70109","DOIUrl":"10.1002/mrc.70109","url":null,"abstract":"<div>\u0000 \u0000 <p>Solid-state NMR experiments provide valuable insights into the structure of pharmaceutical compounds, many of which contain nitrogen. Recent literature indicates that the indirect detection of ¹⁴N offers significant advantages for structural analysis, particularly when using two-dimensional ¹H-¹⁴N HMQC experiments. The advantage of these experiments is that they allow us to rapidly collect information about the hydrogen bonding interaction with a minimal amount of the compound. In our study, we have carried out ¹H-¹⁴N HMQC experiments on structurally similar pharmaceutical compounds sorafenib and regorafenib monohydrate to explore the hydrogen bonding interactions and differentiate different nitrogen signals which are difficult to obtain using ¹⁵N solid-state NMR experiments on unlabeled compounds. Our findings enable us to distinguish between intramolecular and intermolecular hydrogen bonding interactions and identify different nitrogen atoms in their structures. Thus, our results show that the ¹H-¹⁴N HQMC experiments provide a rapid and effective method for distinguishing different hydrogen bonding interactions.</p>\u0000 </div>","PeriodicalId":18142,"journal":{"name":"Magnetic Resonance in Chemistry","volume":"64 8","pages":"682-689"},"PeriodicalIF":2.1,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147774630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}