{"title":"[THE SYSTEMIC IMMUNITY CELLULAR LINK REACTION IN PATIENTS WITH TRAUMATIC ILLNESS].","authors":"I M Plehutsa, R I Sydorchuk, O M Plehutsa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of trauma on parameters of cellular immunity changes is studied. The study includes 52 patients with various forms of traumatic illness, aged 18-69 years (37.91-4.28). The control group consisted of 16 patients who underwent routine surgery not related to the pathology of musculoskeletal system. All patients of the main group were divided into 3 groups according to severity of the condition. Analysis of parameters of cellular link of immune system was performed by defining subpopulations of T-lymphocytes in indirect immunofluorescence method using a panel of monoclonal antibodies for CD3, CD4, CD8, CD22 lymphocytes' receptors and calculation of integrated indicators. The highest expression (immune disorders of II-III grades) of changes of cellular immunity observed in patients with severe traumatic: illness (expand clinical picture). Surgical intervention, even without traumatic injury significantly impact cellular immunity, but in patients with traumatic illness immunity violation were significantly higher than in comparison groups patients except immunoregulatory index.</p>","PeriodicalId":18100,"journal":{"name":"Likars'ka sprava","volume":" ","pages":"26-32"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33426334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[THE EFFECTIVENESS OF A 10-DAY DRUG THERAPY IN CHILDREN WITH CHRONIC GASTRODUODENAL PATHOLOGY ASSOCIATED WITH CAGA-POSITIVE STRAINS OF HELICOBACTER PYLORI].","authors":"V M Dudnyk, G M Rudenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The results of triple Helicobacter-therapy (omeprazole, amoxicillin, nifuratel) in the treatment of chronic gastroduodenal pathology in children depending on the duration of it's use. The effectiveness of drug therapy was evaluated in terms of eradication of Helicobacter pylori and dynamics of pain, dyspeptic syndrome and astenovegetative syndrome.</p>","PeriodicalId":18100,"journal":{"name":"Likars'ka sprava","volume":" ","pages":"147-8"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33424696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L A Sivak, N N Maidanevich, S A Lyalkin, E M Aleksik, A V Askolskiy, M Y Klimanov, N V Kasap
{"title":"[THE TOXIC EFFECTS OF CHEMOTHERAPY ON THE GASTROINTESTINAL TRACT].","authors":"L A Sivak, N N Maidanevich, S A Lyalkin, E M Aleksik, A V Askolskiy, M Y Klimanov, N V Kasap","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chemotherapy in modern oncology is one of the main methods of treatment, along with surgery and radiotherapy techniques. More than 60% of patients receiving chemotherapy at different stages of treatment. Recently, modern chemotherapy has become more urgent personal approach to the choice of drugs and their doses, aimed at reducing the toxicity of chemotherapy. Complications of chemotherapy significantly degrade the effectiveness of the treatment of patients with malignant tumors, because they require lower doses of anticancer drug, or lengthening the intervals between cycles of chemotherapy, which affects treatment outcomes and quality of life.</p>","PeriodicalId":18100,"journal":{"name":"Likars'ka sprava","volume":" ","pages":"108-12"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33425756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[CHILDREN WITH COMMUNITY-ACQUIRED PNEUMONIA HAVE DEFICIENCY OF VITAMINS].","authors":"S L Nyankovskyy, I V Babik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In Ukraine about 90 thousand children and adolescents under the age of 17 years are sick with pneumonia every year. Community-acquired pneumonia continues to be a common and serious illness. In this open single center study involved 120 children of both sexes. We received deficient content of the serum trace elements.</p>","PeriodicalId":18100,"journal":{"name":"Likars'ka sprava","volume":" ","pages":"153-4"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33426163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[GENETIC ASPECTS OF CHRONIC GLOMERULONEPHRITIS].","authors":"V Dudnyk, A Zvenigorodska, G Guminska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of our work was to determine the the gene polymorphism of IL-1β in children with chronic glomerulonephritis. there has been defined the frequency of combinations of allelic variants of cytokines genes of IL-1β and IL-10 in chronic glomerulonephritis in children and found the connection of allelic polymorphism with the disease course, indices of hemopoiesis and IL-1β in serum. The presence of C/T genotype is associated with increased production of interleukin-1β in serum. Genetic polymorphism of genes of interleukin can be a new marker of progression of chronic kidney disease.</p>","PeriodicalId":18100,"journal":{"name":"Likars'ka sprava","volume":" ","pages":"159-60"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33426169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[FEATURES OF TREATMENT OF EOSINOPHILIC ESOPHAGITIS IN SCHOOLCHILDREN].","authors":"M I Horodylovska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The inclusion of probiotic L. reuteri into the complex therapy of eosinophilic esophagitis significantly affect the outcomes of children--there was significant decrease in the number of eosinophils in the esophageal mucosa of children.</p>","PeriodicalId":18100,"journal":{"name":"Likars'ka sprava","volume":" ","pages":"144-5"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33424697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[PLEURECTOMY--AS THE LEADING METHOD OF FUNCTIONAL PATIENTS REHABILITATION WITH CHRONIC TUBERCULOUS PLEURISY].","authors":"I D Duzhiy, I Y Gresko, R Z Elastal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors are analyzing the epidemic situation in Ukraine and the epidemiology of chronic tuberculous pleuritis (CTP). They are suggesting 206 pleurectomy results of operated patiens. Restrictive type of venting disorders before surgery occurred are in 26.4% cases, 36.2% and 100%, respectively at 1; 2 and 3 stages of CTP. Reducing the number of patients with this type of violations occurred if 6.9 times, 11.7 times and 3.3 times respectively to operated in case of 1, 2 and 3 stages of CTP. Improvements and other positive functional parameters are submitted. The authors conclusion: pleurectomy is the method of functional rehabilitation at CTP cases.</p>","PeriodicalId":18100,"journal":{"name":"Likars'ka sprava","volume":" ","pages":"77-80"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33425748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[OPTIMIZING PROPHYLAXIS OF BEHAVIORAL RISK FACTORS IN THE PRACTICE OF A HEALTH PRACTITIONER].","authors":"A S Biduchak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A functionally organizational model of the work of a medical worker has been elaborated on the basis of the prophylaxis of diseases of the circulatory system whose basis is a correction of behavioral risk factors.</p>","PeriodicalId":18100,"journal":{"name":"Likars'ka sprava","volume":" ","pages":"112-5"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33425752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[THE VALUE OF RECURRENT BRONCHIAL OBSTRUCTION ASSOCIATED WITH RESPIRATORY INFECTIONS IN INFANTS].","authors":"O O Yukhimenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It is shown that recurrent bronchial obstruction with nonallergic genesis is a significant problem for young children. Further researches of this disease are needed in order to develop differentiated therapies.</p>","PeriodicalId":18100,"journal":{"name":"Likars'ka sprava","volume":" ","pages":"150-1"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33426160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[BCL1 POLYMORPHISM OF GLUCOCORTICOID RECEPTOR GENE AND RESPIRATORY DISEASES].","authors":"L N Prystupa, V Yu Garbuzova, V V Kmyta","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The article analyses the results of investigating the connection between BCL1-polymorphism of glucocorticoid receptor gene and respiratory diseases. Its role in increasing sensitivity to glucocorticoids is proved here. The authors investigated the association of Bcl1 polymorphism with predisposition to bronchial asthma, chronic obstructive pulmonary disease, with the nicotine addiction degree and with progressing disorders of pulmonary function in cystic fibrosis.</p>","PeriodicalId":18100,"journal":{"name":"Likars'ka sprava","volume":" ","pages":"43-8"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33426338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}