Laryngo-rhino-otologiePub Date : 2024-11-01Epub Date: 2024-11-04DOI: 10.1055/a-2365-9717
{"title":"Budesonid-Therapie bei chronischer Rhinosinusitis mit Nasenpolypen.","authors":"","doi":"10.1055/a-2365-9717","DOIUrl":"https://doi.org/10.1055/a-2365-9717","url":null,"abstract":"","PeriodicalId":17965,"journal":{"name":"Laryngo-rhino-otologie","volume":"103 11","pages":"769-770"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142576222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laryngo-rhino-otologiePub Date : 2024-11-01Epub Date: 2024-11-04DOI: 10.1055/a-2358-2040
Stefan Dazert, Timo Stöver, Andreas Neumann, Thomas Deitmer
{"title":"Liebe Leserinnen, liebe Leser der LRO.","authors":"Stefan Dazert, Timo Stöver, Andreas Neumann, Thomas Deitmer","doi":"10.1055/a-2358-2040","DOIUrl":"https://doi.org/10.1055/a-2358-2040","url":null,"abstract":"","PeriodicalId":17965,"journal":{"name":"Laryngo-rhino-otologie","volume":"103 11","pages":"764-765"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142576253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laryngo-rhino-otologiePub Date : 2024-11-01Epub Date: 2024-11-04DOI: 10.1055/a-2358-1873
J A Werner, J P Windfuhr
{"title":"Eingriffe an Larynx, Hypopharynx und Trachea.","authors":"J A Werner, J P Windfuhr","doi":"10.1055/a-2358-1873","DOIUrl":"https://doi.org/10.1055/a-2358-1873","url":null,"abstract":"","PeriodicalId":17965,"journal":{"name":"Laryngo-rhino-otologie","volume":"103 11","pages":"820-822"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142576227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laryngo-rhino-otologiePub Date : 2024-11-01Epub Date: 2024-11-04DOI: 10.1055/a-2365-9643
{"title":"Kommentar zu: Budesonid-Therapie bei chronischer Rhinosinusitis mit Nasenpolypen.","authors":"","doi":"10.1055/a-2365-9643","DOIUrl":"https://doi.org/10.1055/a-2365-9643","url":null,"abstract":"","PeriodicalId":17965,"journal":{"name":"Laryngo-rhino-otologie","volume":"103 11","pages":"770-771"},"PeriodicalIF":0.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142576249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Louis Jansen, Lisa Nachtsheim, Marcel Mayer, Christoph Arolt, Alexander Quaas, Jens Peter Klußmann, Philipp Wolber
{"title":"[Clinical and molecular epidemiology of malignant salivary gland tumors].","authors":"Louis Jansen, Lisa Nachtsheim, Marcel Mayer, Christoph Arolt, Alexander Quaas, Jens Peter Klußmann, Philipp Wolber","doi":"10.1055/a-2373-5741","DOIUrl":"https://doi.org/10.1055/a-2373-5741","url":null,"abstract":"<p><p>Salivary gland carcinomas are a rare and heterogeneous group of malignant tumors, accounting for 3-6% of all malignant tumors in the head and neck region. The 1-, 3- and 5-year survival rates are 83%, 69% and 63% respectively. Due to new molecular pathological and genetic findings, new entities are constantly being defined as part of the recurring WHO classification of salivary gland carcinomas, so that the incidence rates of the entities are subject to constant change. The only certain risk factor for the development of salivary gland carcinomas is ionizing radiation. In addition, large tumors, cervical lymph node involvement and perineural sheath involvement significantly worsen the prognosis. Today, molecular pathology is coming to the fore, with which potential targets have been identified that can offer prognosis-improving treatment options, particularly in recurrent or distant metastatic stages. Entity-specific tyrosine kinase inhibitors such as axitinib in adenoid cystic carcinoma or larotrectinib in secretory carcinoma and cross-entity therapies such as HER2 inhibition and androgen deprivation can prolong median and progression-free survival with a favorable side effect profile.</p>","PeriodicalId":17965,"journal":{"name":"Laryngo-rhino-otologie","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Schadensersatzansprüche bei nicht rechtzeitig geschlossener Zielvereinbarung.","authors":"Kim-Victoria Seibert","doi":"10.1055/a-2347-7765","DOIUrl":"https://doi.org/10.1055/a-2347-7765","url":null,"abstract":"","PeriodicalId":17965,"journal":{"name":"Laryngo-rhino-otologie","volume":"103 10","pages":"732-733"},"PeriodicalIF":0.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}