Kidney MedicinePub Date : 2025-06-17eCollection Date: 2025-08-01DOI: 10.1016/j.xkme.2025.101048
Rajavee A Panchal, Heather Rytting, Amirtha V Chinnadurai, Larry A Greenbaum
{"title":"Dietary Oxalate Nephropathy Due to Pureed Feeds.","authors":"Rajavee A Panchal, Heather Rytting, Amirtha V Chinnadurai, Larry A Greenbaum","doi":"10.1016/j.xkme.2025.101048","DOIUrl":"10.1016/j.xkme.2025.101048","url":null,"abstract":"<p><p>An 8-year-old boy with a 5q14.3 deletion presented with an elevated serum creatinine level of 1.8 mg/dL. A kidney biopsy demonstrated tubular injury and extensive oxalate crystals. His serum and urinary oxalate levels were elevated, but genetic testing for primary hyperoxaluria was negative. The patient depended on pureed foods for nutrition, and his mother consistently used a large amount of spinach and nuts when preparing his blenderized feeds. Hence, his dietary intake of oxalate was extremely high. After dietary modification, his serum and urinary oxalate levels decreased, but his serum creatinine levels had increased to 2.1 mg/dL. Unfortunately, the reported outcome of secondary oxalate nephropathy is poor, with no patients having a full recovery and the majority developing kidney failure. Children on pureed foods are at risk of hyperoxaluria if there is a chronic high intake of foods with elevated oxalate content, and caregivers may not realize that healthy foods such as spinach and nuts are high in oxalate. Nutritional counseling of children on pureed foods should include screening for excessive oxalate intake, especially if there is a decrease in kidney function or kidney stones.</p>","PeriodicalId":17885,"journal":{"name":"Kidney Medicine","volume":"7 8","pages":"101048"},"PeriodicalIF":3.4,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12304925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kidney MedicinePub Date : 2025-06-17eCollection Date: 2025-08-01DOI: 10.1016/j.xkme.2025.101052
Wannasit Wathanavasin, Charat Thongprayoon, Paul W Davis, Wisit Cheungpasitporn
{"title":"The Efficacy and Safety of Technology-Guided Dry Weight Adjustment Among Dialysis Patients: A Meta-analysis of Randomized Controlled Trials.","authors":"Wannasit Wathanavasin, Charat Thongprayoon, Paul W Davis, Wisit Cheungpasitporn","doi":"10.1016/j.xkme.2025.101052","DOIUrl":"10.1016/j.xkme.2025.101052","url":null,"abstract":"<p><strong>Rationale & objective: </strong>Recently, various instrumental techniques adjunct to standard clinical evaluation have been used to improve fluid balance and guide dry weight adjustments in dialysis populations. We aimed to explore the efficacy and safety of using technology-guided dry weight adjustment among dialysis patients.</p><p><strong>Study design: </strong>Systematic review and meta-analysis of randomized controlled trials (RCTs). The search was conducted in PubMed, Scopus, and Cochrane Central Register of Controlled Trials for relevant RCTs published until April 28, 2024.</p><p><strong>Setting & participants: </strong>Adult patients with kidney failure with replacement therapy.</p><p><strong>Exposure: </strong>Studies with patients receiving technology-guided dry weight adjustments.</p><p><strong>Outcomes: </strong>Studies were selected if they reported at least 1 outcome of interest (eg, mortality, cardiovascular [CV] events, hospitalization, intradialytic hypotension, hypovolemic events, cardiac arrhythmia, or vascular access problems).</p><p><strong>Analytical approach: </strong>Random-effects meta-analyses were conducted, with risk of bias within studies assessed using version 2 of the Cochrane risk-of-bias tool for randomized trials.</p><p><strong>Results: </strong>A total of 21 RCTs involving 4,239 dialysis patients were analyzed. The meta-analysis revealed that the incorporating technology-guided dry weight adjustment not only was associated with a significant 21% reduction in CV events (relative risk, 0.79; 95% confidence interval [CI], 0.71-0.88) but also resulted in a significant 9% increase in muscle cramps (rate ratio, 1.09; 95% CI, 1.02-1.16). In a subgroup analysis, using bioelectrical impedance analysis was associated with a significant reduction in mortality (relative risk, 0.67; 95% CI, 0.51-0.89). In addition, the intervention led to a significant reduction in pulse wave velocity (mean difference, -2.43 m/s; 95% CI, -4.64 to -0.21).</p><p><strong>Limitations: </strong>Large number of studies with some concerns or a high risk of bias.</p><p><strong>Conclusions: </strong>Technology-guided strategies for dry weight adjustment significantly reduce CV events and may lower all-cause mortality in dialysis patients. These benefits are particularly evident with bioelectrical impedance analysis--guided interventions. Nonetheless, clinicians should be aware of a modestly increased risk of muscle cramps.</p>","PeriodicalId":17885,"journal":{"name":"Kidney Medicine","volume":"7 8","pages":"101052"},"PeriodicalIF":3.4,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kidney MedicinePub Date : 2025-06-16eCollection Date: 2025-08-01DOI: 10.1016/j.xkme.2025.101044
Alexander L Bullen, Ashutosh Tamhane, Dena E Rifkin, Pranav S Garimella, Simon B Ascher, Michael G Shlipak, Edward D Siew, Byron C Jaeger, Joseph V Bonventre, Felipe A Guerrero, Jesse Seegmiller, Henry E Wang, Orlando M Gutierrez, Joachim H Ix
{"title":"Markers of Kidney Tubule Secretion and Future Risk of Sepsis-Associated Acute Kidney Injury Among REGARDS Participants.","authors":"Alexander L Bullen, Ashutosh Tamhane, Dena E Rifkin, Pranav S Garimella, Simon B Ascher, Michael G Shlipak, Edward D Siew, Byron C Jaeger, Joseph V Bonventre, Felipe A Guerrero, Jesse Seegmiller, Henry E Wang, Orlando M Gutierrez, Joachim H Ix","doi":"10.1016/j.xkme.2025.101044","DOIUrl":"10.1016/j.xkme.2025.101044","url":null,"abstract":"","PeriodicalId":17885,"journal":{"name":"Kidney Medicine","volume":"7 8","pages":"101044"},"PeriodicalIF":3.4,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kidney MedicinePub Date : 2025-06-16eCollection Date: 2025-08-01DOI: 10.1016/j.xkme.2025.101045
Benjamin Grobman, Ruth-Alma Turkson-Ocran, Mingyu Zhang, Stephen P Juraschek
{"title":"Socioeconomic Status and Chronic Kidney Disease Among Black and White Adults: An Analysis of 2017-2020 NHANES.","authors":"Benjamin Grobman, Ruth-Alma Turkson-Ocran, Mingyu Zhang, Stephen P Juraschek","doi":"10.1016/j.xkme.2025.101045","DOIUrl":"10.1016/j.xkme.2025.101045","url":null,"abstract":"<p><strong>Rationale & objective: </strong>Chronic kidney disease (CKD) disproportionately affects Black adults and those with lower socioeconomic status in the United States. The aim of this study was to examine the associations between socioeconomic status and CKD, albuminuria/stage 1-2 CKD, and stage 3-5 CKD, and to assess differences between Black and White adults.</p><p><strong>Study design: </strong>We used data from the 2017-2020 National Health and Nutrition Examination Survey. CKD was defined as an estimated glomerular filtration rate of <60 mL/min/1.73 m<sup>2</sup> based on the race-free CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equation (stage 3-5 CKD) and/or a urinary albumin-creatinine ratio of >30 mg/g (albuminuria/stage 1-2 CKD).</p><p><strong>Setting & participants: </strong>Respondents to the 2017-2020 National Health and Nutrition Examination Survey with Black or White race.</p><p><strong>Exposure: </strong>Measures of socioeconomic status (income to poverty ratio, insurance status, education, employment status, and health care access).</p><p><strong>Analytical approach: </strong>We examined the relationship between measures of socioeconomic status and CKD, albuminuria/stage 1-2 CKD, and stage 3-5 CKD using survey-weighted Poisson regressions controlling for age, sex, and medical comorbid conditions.</p><p><strong>Results: </strong>The weighted sample (<i>N</i> = 182,622,525) was 52.2% women and 15.5% Black, with a mean age of 49.1 years. The prevalence of CKD was 15.6% in the overall sample, 20.9% among Black adults, and 14.7% among White adults. Higher income, higher education levels, and having health insurance were associated with a lower prevalence of CKD in the overall sample and among White adults, but not among Black adults. This pattern was consistent for those with albuminuria/stage 1-2 CKD, but not for those with stage 3-5 CKD.</p><p><strong>Limitations: </strong>This study is limited by its cross-sectional design. In addition, data were based on single measurements and thus may be less precise in estimating the prevalence of chronic disease.</p><p><strong>Conclusions: </strong>Higher socioeconomic status was inversely associated with albuminuria/stage 1-2 CKD and CKD among White but not Black adults. Future work should investigate the mechanisms by which albuminuria/stage 1-2 CKD remains independent of socioeconomic status among Black adults.</p>","PeriodicalId":17885,"journal":{"name":"Kidney Medicine","volume":"7 8","pages":"101045"},"PeriodicalIF":3.4,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kidney MedicinePub Date : 2025-06-14eCollection Date: 2025-08-01DOI: 10.1016/j.xkme.2025.101046
Annemarie Albert, Ulrich Paul Hinkel, Theresa Bohlender, Philipp Stieger, Rüdiger C Braun-Dullaeus, Christian Albert
{"title":"Paradoxical Inadequate Parathyroid Hormone Secretion Secondary to Severe Hypomagnesemia: A Review of the Literature.","authors":"Annemarie Albert, Ulrich Paul Hinkel, Theresa Bohlender, Philipp Stieger, Rüdiger C Braun-Dullaeus, Christian Albert","doi":"10.1016/j.xkme.2025.101046","DOIUrl":"10.1016/j.xkme.2025.101046","url":null,"abstract":"<p><p>Hypocalcemia is a common manifestation frequently encountered secondary to hypomagnesemia. Both calcium and magnesium are essential for maintaining normal cellular physiology, and magnesium plays a pivotal role in modulating neuronal excitation, intracardiac conduction, and myocardial contraction by regulating several ion transporters. Associated disorders may include cardiac arrhythmia, heart failure due to insufficient contractility, and neuromuscular and central nervous system conditions with seizures. One of the most important factors underlying hypocalcemia in hypomagnesemia conditions is the impaired secretion of parathyroid hormone (PTH), referred to as paradoxical hypoparathyroidism. Because there is a positive functional correlation and association between serum magnesium and calcium concentrations, clinical hypocalcemia in cases of magnesium deficiency cannot be sufficiently corrected by supplementation with calcium, vitamin D, or both. In contrast to the clinical relevance of a rapid, consequent and effective detection, differential diagnosis, and subsequent initiation of an appropriate therapy, this phenomenon and underlying pathophysiology are not well understood. In this review we summarize on calcium and magnesium homeostasis through modulation of PTH and vitamin D and elaborate on the mechanism underlying the rare condition of paradoxical inadequate PTH secretion. Based on the relevant literature, our review includes interdisciplinary diagnostic and therapeutic recommendations.</p>","PeriodicalId":17885,"journal":{"name":"Kidney Medicine","volume":"7 8","pages":"101046"},"PeriodicalIF":3.4,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kidney MedicinePub Date : 2025-06-14eCollection Date: 2025-08-01DOI: 10.1016/j.xkme.2025.101047
Shane A Bobart, Enshuo Hsu, Thomas Potter, Luan Truong, Amy Waterman, Stephen Jones, Tariq Shafi
{"title":"Development of a Natural Language Processing Model for Extracting Kidney Biopsy Pathology Diagnoses.","authors":"Shane A Bobart, Enshuo Hsu, Thomas Potter, Luan Truong, Amy Waterman, Stephen Jones, Tariq Shafi","doi":"10.1016/j.xkme.2025.101047","DOIUrl":"10.1016/j.xkme.2025.101047","url":null,"abstract":"<p><strong>Rationale & objective: </strong>Kidney biopsy reports are in a nonindexed text format, and the diagnosis requires labor-intensive manual abstraction. Natural language processing (NLP) has not been rigorously tested for kidney biopsy diagnosis extraction. Our objective was to develop an accurate model to extract the biopsy diagnosis from free-text reports.</p><p><strong>Study design: </strong>Text classification using NLP.</p><p><strong>Setting & participants: </strong>2,666 patients with 3,042 native kidney biopsy reports in the Portable Document Format, from June 2016 to December 2023.</p><p><strong>Predictor: </strong>Kidney biopsy diagnosis.</p><p><strong>Outcomes: </strong>The performance of the NLP algorithm for all and the 20 most common diagnoses based on precision, recall, F1 score, and area under the receiver operating curve (AUROC).</p><p><strong>Analytical approach: </strong>A domain expert manually abstracted the diagnosis, and a renal pathologist validated a random subset (n = 200). Structured Query Language server and Python processed reports into machine-readable free text. We used PubMed Bidirectional Encoder Representations from Transformers to develop our NLP algorithm. We randomly split the reports into training (80%; n = 2,434) and testing (20%; n = 608) sets to train the NLP system. We further divided the testing set into 20% validation and 80% fine-tuning sets.</p><p><strong>Results: </strong>The median age was 57 years, with 50% female, 29% African Americans, and 23% Hispanic participants. The 5 most frequent glomerular diagnoses were diabetic kidney disease (23.7%), focal segmental glomerulosclerosis (15.5%), lupus nephritis (9.7%), immunoglobulin A nephropathy (8.9), and membranous nephropathy (7.2%). The Cohen kappa coefficient for interrater reliability was 0.76. PubMed Bidirectional Encoder Representations from Transformers fine-tuned with a training set showed the average AUROC for NLP performance in the testing set of 0.95 across all diagnoses with an F1 score of 0.57. For the 20 most common diagnoses, the AUROC was 0.97 with an F1 score of 0.72. Limitations: Single centered; sample size and use limited to research purposes.</p><p><strong>Conclusions: </strong>We demonstrate an accurate and scalable NLP system to extract the primary diagnosis from free-text kidney biopsy reports, which can facilitate epidemiologic studies and identify patients for clinical trial recruitment.</p>","PeriodicalId":17885,"journal":{"name":"Kidney Medicine","volume":"7 8","pages":"101047"},"PeriodicalIF":3.4,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12311501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kidney MedicinePub Date : 2025-06-03eCollection Date: 2025-08-01DOI: 10.1016/j.xkme.2025.101043
Jing Wu, Sufang Shi, Xujie Zhou, Lijun Liu, Jicheng Lv, Li Zhu, Suxia Wang, Hong Zhang
{"title":"The Proportion of New-Onset Microangiopathic Lesions in IgA Nephropathy is Increased After COVID-19 Pandemic in China.","authors":"Jing Wu, Sufang Shi, Xujie Zhou, Lijun Liu, Jicheng Lv, Li Zhu, Suxia Wang, Hong Zhang","doi":"10.1016/j.xkme.2025.101043","DOIUrl":"10.1016/j.xkme.2025.101043","url":null,"abstract":"<p><strong>Rationale & objective: </strong>New-onset IgA nephropathy (IgAN) and thrombotic microangiopathy (TMA) cases were reported after COVID-19 pandemic. This study investigated the prevalence and characteristics of IgAN-MA lesions in IgAN after the COVID-19 pandemic in China.</p><p><strong>Study design: </strong>A cross-sectional study.</p><p><strong>Setting & participants: </strong>A total of 22,123 biopsied patients, mainly in northern China from June 1, 2018, to May 31, 2024 were enrolled.</p><p><strong>Exposure: </strong>COVID-19 pandemic in China.</p><p><strong>Analytical approach: </strong>Cochran-Armitage trend test was used to detect trends of IgAN and MA lesions after COVID-19 pandemic. Stage 1 represented no COVID-19 infection (including Stage 1A); Stage 2 represented possible COVID-19 infection and vaccination implemented; Stage 3 represented COVID-19 infection (including Stage 3A and Stage 3B). Multivariate logistic regression was used to analyze risk factors of MA lesions.</p><p><strong>Results: </strong>The proportion of IgAN in total biopsies and MA lesions in IgAN showed an increasing trend over time. In Stage 1, IgAN comprised 22.6% of total biopsies, significantly lower than the proportion in Stage 3 (24.5%; <i>P</i> = 0.01) after bias adjusted. The MA lesions increased notably from 3.6% in Stage 1 to 10.1% in Stage 2 and continued to increase to 15.4% in Stage 3 (<i>P</i> <i><</i> 0.001). Immunofluorescence showed a progressive increase in C3 deposition in patients with IgAN and patients with MA in Stage 1A, Stage 3A, and Stage 3B (all <i>P</i> < 0.05). Multivariable logistic regression identified pandemic exposure, increased mean arterial pressure, lower estimated glomerular filtration rate, S1 lesions, and T1/T2 lesions as risk factors for the development of MA lesions.</p><p><strong>Limitations: </strong>Proportion based on patients in northern China, diagnosis from medical records without re-evaluation, lack of exact data on vaccination status and COVID-19 infection, lack of prognosis.</p><p><strong>Conclusions: </strong>COVID-19 may promote the proportion of IgAN in total biopsy and MA lesions in IgAN. Complement activation may play an important role in the development of IgAN and MA lesions.</p>","PeriodicalId":17885,"journal":{"name":"Kidney Medicine","volume":"7 8","pages":"101043"},"PeriodicalIF":3.4,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12311513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kidney MedicinePub Date : 2025-06-02eCollection Date: 2025-08-01DOI: 10.1016/j.xkme.2025.101042
Benjamin Lazarus, Sradha Kotwal, Martin Gallagher, Kathryn Higgins, Sarah Coggan, Nicholas A Gray, Girish Talaulikar, Kevan R Polkinghorne
{"title":"Prophylactic Antibiotics Before Insertion of Tunneled Hemodialysis Catheters: A Nationwide Cohort Study.","authors":"Benjamin Lazarus, Sradha Kotwal, Martin Gallagher, Kathryn Higgins, Sarah Coggan, Nicholas A Gray, Girish Talaulikar, Kevan R Polkinghorne","doi":"10.1016/j.xkme.2025.101042","DOIUrl":"10.1016/j.xkme.2025.101042","url":null,"abstract":"<p><strong>Rationale & objective: </strong>It is unknown whether administration of prophylactic systemic antibiotics immediately before tunneled catheter insertion can prevent early hemodialysis catheter-related bloodstream infections (HDCRBSI). We aimed to estimate the effect of systemic prophylactic antibiotics on early HDCRBSI.</p><p><strong>Study design: </strong>An observational secondary analysis using data from the nationwide REDUcing the burden of dialysis Catheter ComplicaTIOns: a National approach trial.</p><p><strong>Setting & participants: </strong>Adults with an incident hemodialysis catheter inserted in one of 37 Australian nephrology services from December 2016 to March 2020.</p><p><strong>Exposure: </strong>Service-wide policy of systemic prophylactic antibiotic use before tunneled catheter insertion determined by response to a prestudy survey.</p><p><strong>Outcome: </strong>HDCRBSI within 14 days of catheter insertion, independently adjudicated by a blinded panel using modified Infectious Diseases Society of America criteria.</p><p><strong>Analytical approach: </strong>Multilevel logistic regression to compare outcomes among antibiotic-using and nonusing services.</p><p><strong>Results: </strong>Six services (900 patients) used prophylactic antibiotics, and 23 services (3,702 patients) did not. Among the 1,196 tunneled catheters that were inserted in antibiotic-using services, 4 (0.3%) had HDCRBSI and another 10 (0.8%) had infectious removal within 14 days of insertion. Among the 5,027 tunneled catheters inserted in nonantibiotic-using services, 40 (0.8%) had HDCRBSI and another 41 (0.8%) had infectious removal within 14 days. The odds of early HDCRBSI were not significantly different between antibiotic-using and nonusing services in the unadjusted (OR, 0.42; 95% CI, 0.15-1.17) or adjusted models (adjusted OR, 0.59; 95% CI, 0.20-1.80).</p><p><strong>Limitations: </strong>Prophylactic systemic antibiotic use was determined at a service level and was not randomly assigned to individuals.</p><p><strong>Conclusions: </strong>In Australia, less than 1% of tunneled catheters had confirmed HDCRBSI within 14 days of insertion. Routine administration of prophylactic antibiotics before insertion of tunneled cuffed catheters was not associated with a reduced occurrence of early HDCRBSI within 14 days.</p>","PeriodicalId":17885,"journal":{"name":"Kidney Medicine","volume":"7 8","pages":"101042"},"PeriodicalIF":3.4,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12304927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kidney MedicinePub Date : 2025-06-01DOI: 10.1016/j.xkme.2025.101034
Samuel Moen MPH, James Pankow PhD, Sanaz Sedaghat PhD
{"title":"Reply: Comment on “Kidney Function and Incident Stroke and Dementia Using an Updated Estimated Glomerular Filtration Rate Equation Without Race: The Multi-Ethnic Study of Atherosclerosis”","authors":"Samuel Moen MPH, James Pankow PhD, Sanaz Sedaghat PhD","doi":"10.1016/j.xkme.2025.101034","DOIUrl":"10.1016/j.xkme.2025.101034","url":null,"abstract":"","PeriodicalId":17885,"journal":{"name":"Kidney Medicine","volume":"7 6","pages":"Article 101034"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kidney MedicinePub Date : 2025-06-01DOI: 10.1016/j.xkme.2025.101032
Maxime Ingwiller MD , Thierry Hannedouche MD, PhD
{"title":"Response to the letter by Ito","authors":"Maxime Ingwiller MD , Thierry Hannedouche MD, PhD","doi":"10.1016/j.xkme.2025.101032","DOIUrl":"10.1016/j.xkme.2025.101032","url":null,"abstract":"","PeriodicalId":17885,"journal":{"name":"Kidney Medicine","volume":"7 6","pages":"Article 101032"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}