Kyobu geka. The Japanese journal of thoracic surgery最新文献

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[Current Status of Implantable Ventricular Assist Device]. 植入式心室辅助装置的现状
Yangsin Lee, Masahiko Ando, Minoru Ono
{"title":"[Current Status of Implantable Ventricular Assist Device].","authors":"Yangsin Lee, Masahiko Ando, Minoru Ono","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Implantable ventricular assist device( iVAD) was initially approved in Japan as bridge-to-transplantation( BTT) indication in 2011. Since then, 1,458 iVAD implants were performed as BTT, and this number per year is rapidly increasing, especially after the approval of iVAD implant as destination therapy (DT) indication in 2021. Some of DT patients will be eventually registered for heart transplantation, once their exclusion criteria are cleared, thus extending waiting time of BTT patients in the setting of serious donor shortage in Japan. Therefore, to improve the outcome of iVAD patients, both BTT and DT, it is imperative to manage device-associated complications that can occur during prolonged longterm iVAD support. In the present review, we summarize the recent updates on the iVAD treatment in Japan, in terms of device-associated complications, especially driveline infection, right ventricular failure and aortic regurgitation.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 4","pages":"244-248"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Long-term Outpatient Management and Shared Care Practices to Prevent Rehospitalization and Improve Quality of Life in Patients with Implantable Ventricular Assist Device]. [长期门诊管理和共享护理实践预防再住院和提高植入式心室辅助装置患者的生活质量]。
Yuichiro Kishimoto, Yasushi Yoshikawa
{"title":"[Long-term Outpatient Management and Shared Care Practices to Prevent Rehospitalization and Improve Quality of Life in Patients with Implantable Ventricular Assist Device].","authors":"Yuichiro Kishimoto, Yasushi Yoshikawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>According to a statistical report from the Japanese registry for Mechanically Assisted Circulatory Support, the readmission rate is 85% at three years, mainly due to driveline infection. The prevention of adverse events such as driveline infections is important to improve the quality of life of patients, an issue that needs to be emphasized more in these days when longer waiting periods for transplantation and destination therapy are becoming more common. In addition to monthly outpatient visits, we provide weekly e-mail consultations and promote collaboration with shared care facilities. Our driveline infection rate was 20% at three years, and the readmission rate was an excellent 27% at three years. The results suggest that our long-term outpatient management may have contributed to the improvement of quality of life by reducing adverse events such as driveline infections and preventing rehospitalization.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 4","pages":"267-273"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Driveline Infection of Implantable Left Ventricular Assist Devices]. [植入式左心室辅助装置传动系统感染]。
Haruki Tanaka, Tatsuichiro Seto
{"title":"[Driveline Infection of Implantable Left Ventricular Assist Devices].","authors":"Haruki Tanaka, Tatsuichiro Seto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In Japan, the median waiting period from implantable left ventricular assist device( iLVAD) implantation to heart transplantation is 5.1 years, with driveline infections occurring in approximately 20% of cases within the first year. At our institution, we implemented the triple tunnel method and a structured care protocol to mitigate infection risk. This protocol includes meticulous monitoring, the use of sterilized kits, chlorhexidine, and caregiver training. Among 25 patients, driveline infections occurred in 12% (three cases), but none progressed to pump infections. Kaplan-Meier analysis showed infection-free rates of 100% at one year and 85% at three years, slightly surpassing national benchmarks. These outcomes highlight the importance of early detection, multidisciplinary follow-up, and consistent care in ensuring successful long-term management of iLVAD patients.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 4","pages":"286-291"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Long-term Management of Implantable Left Ventricular Assist Device for Maintaining Quality of Life]. [植入式左心室辅助装置维持生活质量的长期管理]。
Hitoshi Inafuku
{"title":"[Long-term Management of Implantable Left Ventricular Assist Device for Maintaining Quality of Life].","authors":"Hitoshi Inafuku","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The outcomes of implantable left ventricular assist device( iVAD) treatment in Japan are favorable; however, the high rate of re-hospitalization due to complications remains a significant issue. This report details the procedures for iVAD treatment conducted at our hospital. Specifically, we focus on:1. driveline( DL) infection, 2. stroke, and 3. right heart failure. 1. As part of DL infection control, the DL was assumed to enter through the upper umbilicus, and an incision was made from the right side, passing through the left rectus abdominis muscle to the left side. All patients are treated with a simple omental covering, and a new disinfectant, Prontosan, which contains both a surfactant and an antibacterial agent, is used to manage exit site infections involving biofilm. 2. To prevent stroke, all patients are provided with a CoaguChek XS device at discharge, which is adjusted to extend the time required to reach target prothrombin time-international normalized ratio (PT-INR) values. 3. As an innovative approach to treating right heart failure, we have developed a simple or unidirectional valved anastomosis between the superior vena cava and the right pulmonary artery, allowing blood to flow into the pulmonary artery under elevated venous pressure. This procedure is part of a collaborative research project with the School of Science and Engineering at Waseda University( TWIns).</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 4","pages":"312-317"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Outcomes of Implantable Left Ventricular Assist Device for Treating Advanced Heart Faire in Our Institute and Outlook for Long-term Use]. [植入式左心室辅助装置在我院治疗晚期心衰的疗效及长期应用前景]。
Masahiko Ezure
{"title":"[Outcomes of Implantable Left Ventricular Assist Device for Treating Advanced Heart Faire in Our Institute and Outlook for Long-term Use].","authors":"Masahiko Ezure","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>From 2011, 13 patients with implantable ventricular assist device (VAD) have followed in our institute, 11 as a bridge to transplant (BTT), and two as destination therapy (DT). All patients were implanted left VAD (LVAD) in INTERMACS profile level 2 to 4, except two as a bridge to bridge (BTB) cases. The EVAHEART LVAD was selected in four, Jarvic2000 was in four, and HeartMate3 was in five patients. There were no major complications in perioperative period. Outpatient cares were provided by VAD team members every week. Of the 13 patients, six underwent transplant, two died during support and five are ongoing. Support averaged 38 months( three cases over 60 months). Eight patients required rehospitalization for more than one time. First three patients had cerebral hemorrhages in four, 10 and 25 months. One patient suffered severe right heart faire, and was repeatedly hospitalized( 22 times). There was no driveline infection, and no aortic regurgitation over moderate level. Several patients have continued cardiac rehabilitation, and improved physical strength and ventilatory power. Complications caused implantable VAD have been decreasing due to progressions of the device and appropriate managements for outpatient care. The current implantable LVAD can be used safely in advanced heart failure patients not only as BTT but also as DT. We can look forward to improve the technology of implantable VAD system in the future too. However, aging changes will be considered for long term follow-up of the DT patients.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 4","pages":"307-311"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Prevention of Driveline Infection in the HeartMate 3 Era]. [心脏伴侣3时代传动系统感染的预防]。
Tomo Yoshizumi, Masato Mutsuga
{"title":"[Prevention of Driveline Infection in the HeartMate 3 Era].","authors":"Tomo Yoshizumi, Masato Mutsuga","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The current European and United States durable left ventricular assist device( LVAD) registry with HeartMate 3 did not show the improvement of device related infection in the long-term period, even though the early result was getting better because of the improvement of patient selections and surgical techniques. Driveline management protocol was crucial to prevent long-term driveline infection, however, there is no common one and each facility needs to make own protocol. We present our own driveline management protocol derived from our historical experiences and evaluate the effectiveness of our protocol for the prevention of driveline infections.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 4","pages":"279-284"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Current State of Right Heart Failure after Implantable Ventricular Assist Device]. [植入式心室辅助装置后右心衰的现状]。
Naoki Eguchi, Akira Sezai, Masashi Tanaka
{"title":"[Current State of Right Heart Failure after Implantable Ventricular Assist Device].","authors":"Naoki Eguchi, Akira Sezai, Masashi Tanaka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Japanese registry for Mechanically Assisted Circulatory Support (J-MACS) reports on the results of implantable ventricular assist devices (VADs) in Japan show that the survival rates have stabilized at 93% at one year, 90% at two years and 81% at four years. However, the incidence of neurological dysfunction, hemorrhage and infection, the three major complications, has not been resolved, although it has decreased. Right heart failure has also been improved by implantable left VAD (iLVAD) in patients with preoperative biventricular failure. The J-MACS reported right heart failure free rates of 95% at 90 days, 92% at one year, 90% at two years and 84% at four years. Most cases are in the acute phase after iLVAD and often improve with nitric oxide( NO), drugs or a temporary right VAD( RVAD). In Japan, the waiting period for heart transplantation is long due to the shortage of donors, and the period of RVAD support is much longer than in the West. Right heart failure is sometimes observed in the remote period after iLVAD. Severe cases requiring RVAD and biventricular assist device( BiVAD) are treated with early cardiac transplantation in Europe and the United States of America (USA), while cases requiring long-term BiVAD therapy are extremely rare. Therefore, there are currently no clear standards for the indications and management of RVAD. In this report, we discuss domestic and foreign reports on right heart failure after left VAD (LVAD) and report a valuable case in which RVAD was performed three and a half years after iLVAD in our department, and BiVAD management was required for more than one year for heart transplantation.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 4","pages":"293-299"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Durable Left Ventricular Assist Device Therapy for Patients with a Prior MitraClip or Impella Intervention]. 既往有MitraClip或Impella介入的患者的持久左心室辅助装置治疗。
Tomoki Ushijima, Takeo Fujino, Shogo Matsunaga, Satoshi Kimura, Hiromichi Sonoda, Akira Shiose
{"title":"[Durable Left Ventricular Assist Device Therapy for Patients with a Prior MitraClip or Impella Intervention].","authors":"Tomoki Ushijima, Takeo Fujino, Shogo Matsunaga, Satoshi Kimura, Hiromichi Sonoda, Akira Shiose","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Some patients have undergone implantation of a durable left ventricular assist device( LVAD) following heart failure treatment with Impella( Abiomed) or MitraClip( Abbott). Impella may carry a potential risk of de novo aortic insufficiency (AI), while MitraClip may pose hemodynamic issues under LVAD circulation. In this report, we present the outcomes of durable LVAD therapy in patients with these prior treatments. Seventeen patients had previously received Impella support, and five had undergone MitraClip implantation. Among the 17 post-Impella patients, seven underwent aortic valvuloplasty during LVAD implantation, and one required surgical intervention due to AI progression 10 months postoperatively. Of the nine non-interventional patients, one with moderate AI underwent heart transplantation without intervention five years after the LVAD implantation, while the remaining eight patients had mild or less AI. Four of the five post-MitraClip patients underwent mitral valve replace ment with a bioprosthetic valve during LVAD implantation. The remaining non-interventional patient experienced no hemodynamic problems. The number of LVAD therapies for patients with a prior Impella or MitraClip intervention is expected to increase in the future. It is essential to establish an appropriate therapeutic strategy based on detailed and careful evaluations of individual cases.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 4","pages":"249-254"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Treatment Strategy for Implantable Ventricular Assist Device Infections:Is Omental Flap Useful?] 植入式心室辅助装置感染的治疗策略:网膜瓣有用吗?]
Masaomi Fukuzumi
{"title":"[Treatment Strategy for Implantable Ventricular Assist Device Infections:Is Omental Flap Useful?]","authors":"Masaomi Fukuzumi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Infection of implantable ventricular assist device( iVAD) is one of the serious complications for which there is still no established treatment strategy. We evaluated the usefulness of omental flap for device infections. Five of 20 patients of iVAD underwent omental flap for device infections extending to the pump site. Two patients underwent simultaneous omental flap and iVAD exchange, and three patients underwent device sparing. All of the device-sparing cases eventually required iVAD exchange due to recurrent infection. By covering the new pump with an omental flap at the time of iVAD exchange, there were no recurrent infections in any of the cases. Isolated omental flap is difficult to cure the device infections that extend the pump site alone, and iVAD exchange should also be performed, however, it might prevent recurrence of infection on new devices.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 4","pages":"274-278"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[How to Avoid Reoperation for Complications Associated with Durable Mechanical Circulatory Support Therapy]. 如何避免持久机械循环支持治疗相关并发症的再手术。
Tomonori Ooka, Taro Minamida, Hiroshi Sugiki, Yasushige Shingu, Satoru Wakasa
{"title":"[How to Avoid Reoperation for Complications Associated with Durable Mechanical Circulatory Support Therapy].","authors":"Tomonori Ooka, Taro Minamida, Hiroshi Sugiki, Yasushige Shingu, Satoru Wakasa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Since April 2011, durable mechanical circulatory support (DMCS) has been used for bridge to transplant (BTT-DMCS) in Japan, with its success leading to insurance coverage for destination therapy (DT-DMCS) in 2021. Despite advancements, managing DMCS-related complications remains challenging, with high readmission rates impacting patients' quality of life and healthcare facilities' workloads. Key complications include de novo aortic insufficiency (dnAI), driveline infections (DLI), and external outflow graft obstruction( EOGO). dnAI contributes significantly to chronic right heart failure, with no consensus on optimal intervention timing. Techniques such as bioprosthetic aortic valve replacement (bioAVR) and central aortic valve closure( CAVC) are employed, each with distinct benefits and limitations. DLI, often caused by mechicillin-resistant Staphylococcus aureus (MRSA), multidrug-resistant bacteria, or Mycobacterium abscessus, necessitates advanced wound management, driveline translocation, and prolonged antibiotic therapy. Imaging modalities like 18-FDG PET/CT are crucial for accurate diagnosis and treatment planning. EOGO, frequently caused by seroma compression, can lead to circulatory failure and often requires surgical intervention or catheter-based treatments. Preventing reoperations, optimizing intervention timing, and ensuring multidisciplinary collaboration are essential strategies for improving patient outcomes and enhancing the long-term effectiveness of DMCS therapy.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 4","pages":"318-323"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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