{"title":"[Extracorporeal Membrane Oxygenation( ECMO) as an Emerging Technology:Present and Future].","authors":"Masaki Anraku","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Extracorporeal membrane oxygenation (ECMO) has become an essential therapeutic modality for severe respiratory and circulatory failure. Recent technological advances have lowered the operational threshold for ECMO by enabling safer, more portable, and user-friendly systems. This article reviews the latest developments in ECMO-related technologies from the perspective of practicing clinicians. Key topics include the miniaturization and transportability of devices, improvements in centrifugal pumps and membrane lungs, and the incorporation of real-time monitoring and automatic control. Surface coatings using phosphorylcholine or hydrophilic polymers have enhanced biocompatibility and extended device longevity. Artificial intelligence and deep learning are being explored to assist in real-time decision-making and survival prediction. Furthermore, the potential for long-term implantable oxygenators is gaining attention. Our group has demonstrated prolonged in vivo function of a novel silicone membrane lung with methacryloyloxyethyl phosphorylcholine (MPC) polymer coating in large animal models, achieving thrombosis-free support for up to 100 days. The early conceptual framework for an implantable intrathoracic artificial lung, proposed by Mortensen in 1994, is gradually becoming technically feasible thanks to material and design innovations. These multifaceted advancements promise to broaden the future clinical applications of ECMO and improve outcomes across both acute and chronic indications.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 10","pages":"736-739"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Medical Diagnostic Imaging].","authors":"Terunaga Inage, Hidemi Suzuki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Significant advancements in medical imaging technology have been made over the years. Currently, several commercial post-processing software solutions-such as Synapse Vinsent and Ziostation-are available to facilitate the creation of photorealistic three-dimensional (3D) images. Three-dimensional lung reconstruction with virtual modeling offers the opportunity to visualize tumors within the target segment or lobe and to confirm the bronchovascular anatomy, thereby enabling optimal surgical planning. Cross reality (XR)-which includes virtual reality (VR), augmented reality (AR), and mixed reality (MR)-enables surgeons to interact with computer-generated environments based on reality. In thoracic surgery, XR tools support anatomical assessment, surgical training through lifelike procedural simulations, preoperative planning, and intraoperative guidance. Lung perfusion scintigraphy with single photon emission computed tomography (SPECT-CT) allows for quantification of lobar perfusion during preoperative assessment of lung cancer candidates and provides a more accurate prediction of postoperative residual pulmonary function. Fractional flow reserve computed tomography (FFRCT) analysis is a non-invasive diagnostic tool used to determine the physiological impact of coronary artery disease (CAD) in patients with symptoms suggestive of CAD. The FFRCT has been demonstrated to reduce the necessity for invasive coronary angiography that shows no significant CAD. Coronary computed tomography angiography (CCTA) is a highly sensitive method of evaluating vascular anatomy, coronary plaque, calcification and stenosis. The pericoronary fat attenuation index (FAI), a new imaging biomarker derived from CCTA, assesses vascular inflammation by detecting respective gradients in coronary perivascular adipose tissue attenuation. Several studies have shown that elevated pericoronary FAI is associated with vascular inflammation and increased risk of cardiac events.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 10","pages":"757-763"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The Management Methods for Cardiopulmonary Bypass and Control Features in the Modern Heartlung Machines].","authors":"Koichi Kashiwa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>While it may seem that there have been no significant changes in the field of cardiopulmonary bypass (CPB) over the past decade, there have been advances in management concepts, such as coagulation management strategies and the use of oxygen delivery index (DO2i) and carbon dioxide (CO2)-derived variables during CPB. It will be important to examine what changes in outcomes are observed as a result of advances in management methods. The development of a variety of monitoring devices is expected if better outcomes are observed as a result of advances in CPB management. In addition, the introduction and study of different perfusion-assist functions are hoped to lead to the automation of operations in CPB.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 10","pages":"787-792"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Pulmonary Nontuberculous Mycobacteriosis and Cancer at the Same Site:Report of a Case].","authors":"Toshio Nishikawa, Takahiro Inoue, Seiichi Nagahisa, Youko Kuyama, Masahiko Takahashi, Masanobu Mori, Motoki Matsuura, Yasuaki Kamikawa, Fumiyuki Inoue","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 73-year-old man was referred to our hospital for abnormal shadow. Chest computed tomography (CT) showed a tumor with a cavity in S10 of the left lung. Fluorodeoxyglucose-positron emission tomography (FDG-PET) showed the accumulation in the tumorous lesion of the cavity wall. Although the culture of the lavage fluid was positive for acid-fast bacilli and polymerase chain reaction (PCR) was positive for M. intracellulare, coexistence of cancer could not be denied. Therefore, he underwent surgery. Histopathological findings showed squamous cell carcinoma adjacent to epithelioid cell granulomatous lesion of nontuberculous mycobacteriosis.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 9","pages":"723-726"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Surgical Treatment Strategy for Pyothorax in Maintenance Hemodialysis Patients].","authors":"Yoshitaka Tanaka, Yoshio Tsunezuka, Naoki Tsuboniwa, Naoto Izawa, Yuichi Sasaki, Yoshihiko Fu, Ikuho Koyama, Hideki Tsukazaki, Takashi Tsukazaki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Patients on dialysis with end-stage renal failure often develop pleural effusion, which is typically managed by dehydration. However, distinguishing empyema from pleural effusion is crucial, since empyema may not present with typical symptoms like fever, leading to potential misdiagnosis. This study examines the surgical treatment of empyema in dialysis patients. Between 2021 and 2024, among 404 dialysis patients, 5(1.2%)developed empyema. The patients(4 males, 1 female)had a mean age of 69.8 years, and all had diabetic nephropathy-induced renal failure. Two patients presented with asymptomatic pleural effusion, while three patients had fever and leukocytosis. Two patients had encapsulated effusions requiring early surgery. Surgery was performed in four cases after antibiotic treatment, while one received drainage and antibiotics alone. All underwent thoracoscopic procedures, with one patient requiring fenestration for recurrent multidrug-resistant empyema.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 9","pages":"658-663"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Current Status and Future Prospects of Covering, Reinforcement, and Sealant Materials in Thoracic Surgery].","authors":"Hideo Ichimura, Takahiro Yanagihara","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Various types of covering materials, reinforcement materials, and sealants with different compositions and structures are available in the field of thoracic surgery. However, complications such as infection, adhesion, and deformation of the materials, as well as hematoma caused by bleeding, chylothorax from lymphatic leakage, and pneumothorax or empyema due to air leaks, still occur at a certain rate. These issues indicate that the functions of currently available materials do not yet fully meet the needs of thoracic surgeons. In this article, we provide an overview of the classification, characteristics, and limitations of materials currently approved for use in Japan. Furthermore, we introduce recent advances in the development of novel materials-particularly surgical sealants-including an Alaska pollock gelatin sealant that we are co-developing for clinical application. In the development of new materials, improvements in physical properties, along with the availability of different formulations-such as liquid and sheet types-are expected to broaden their clinical applicability. The properties and limitations of each material are closely interrelated, and a thorough understanding of both is essential for optimal material selection and appropriate clinical use.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 10","pages":"764-769"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Aortic Subannular Left Ventricular Pseudoaneurysm with Mitral Valve Regurgitation Due to Infective Endocarditis:Report of a Case].","authors":"Tomohiro Odate, Takashi Miura, Shunsuke Taguchi, Yoichi Hisata, Takafumi Yamada","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The patient was a 40-year-old male. His main complaints were fever and heart failure. Methicillin-sensitive Staphylococcus aureus was isolated from the patient's blood culture. He was diagnosed with a left ventricular pseudoaneurysm by contrast-enhanced computed tomography (CT). Severe mitral insufficiency and vegetation on the anterior mitral valve were observed on echocardiography. The patient went into shock and intratracheal intubation was performed. An intraaortic balloon pumping was started, and percutaneous cardiopulmonary support were established for cardiogenic shock. Mitral valve replacement with a mechanical valve and autologous pericardium patch closure were performed in an urgent surgery. Antibiotics were administered until his inflammatory response was negative. The patient had no recurrence of endocarditis or malfunction of the prosthetic valve and no leakage of the patchplasty for two years post-surgery.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 9","pages":"698-701"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Uniportal Robotic Assisted Pulmonary Resection].","authors":"Naoko Ose, Kaichi Shigetsu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>We introduced the uniportal robotic assisted thoracic surgery (URATS) using da Vinci Xi in 2023 after notification to and approval by the Highly Difficult and New Medical Technology Review Division of the Osaka University Hospital. In our department, URATS is indicated for c-stage 1 lung cancer, metastatic lung tumors, and benign diseases.</p><p><strong>Methods: </strong>The cross-shaped center guide point is aligned with the dorsal surface of the window. The most dorsal arm is not used, and the camera is placed on the dorsal side. The assistant checks which arm is interfering and adjusts the position and height of the port to find a point where there is no interference. It is also important to select a field of view that allows safe manipulation of the target structure without interference, rather than sticking to one field of view.</p><p><strong>Discussion: </strong>One of the advantages of the URATS is that it allows for a close view. While this allows for highly accurate surgery, it also has disadvantages in terms of cost and learning curve. We plan to continue to accumulate and validate cases, as this may be a beneficial treatment option for patients.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 10","pages":"843-848"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Evolution and Future Prospects of Transcatheter Aortic Valve Implantation].","authors":"Hiromichi Sonoda, Akira Shiose","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>With the aging population, the prevalence of aortic stenosis (AS) is increasing, and transcatheter aortic valve implantation (TAVI) has become a promising treatment, particularly for high-risk patients. Over the past decade, TAVI technology has advanced rapidly, and three major devices-SAPIEN (balloon-expandable), Evolut (self-expanding), and Navitor (self-expanding)-are now widely used in Japan. Each device offers unique structural and procedural characteristics: SAPIEN provides precise positioning and strong anti-paravalvular leak features; Evolut offers excellent hemodynamics, especially in small annuli; and Navitor features a flexible delivery system and enhanced sealing via NaviSeal. Long-term data show favorable outcomes for all devices, though each has distinct advantages and limitations. Recent concerns include the management of younger patients and the rise in TAVI explant procedures. Thus, selecting the optimal device based on patient anatomy, risk profile, and future reintervention potential is increasingly emphasized. This review summarizes the key features and clinical outcomes of these devices and discusses future directions toward personalized treatment strategies, including lifetime management approaches. As TAVI expands to lower-risk and younger populations, balancing durability, procedural safety, and reintervention strategies will be essential to ensuring long-term clinical success.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 10","pages":"826-832"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[da Vinci Single-port Esophagectomy via the Subcostal Approach].","authors":"Hiroyuki Daiko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The introduction of the da Vinci SP system has led to the classification of surgical robotic platforms into multiple-port and single-port systems. Esophagectomy for esophageal cancer can now be performed through various approaches, including transthoracic, transcervical, transhiatal, and subcostal routes. Future studies are warranted to determine which robotic system is most suitable for each approach and provides optimal short- and long-term outcomes.</p>","PeriodicalId":17841,"journal":{"name":"Kyobu geka. The Japanese journal of thoracic surgery","volume":"78 10","pages":"888-891"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}