[胸外科覆盖、加固和密封材料的现状及未来展望]。

Q4 Medicine
Hideo Ichimura, Takahiro Yanagihara
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引用次数: 0

摘要

在胸外科领域中,有各种类型的不同成分和结构的覆盖材料、增强材料和密封剂。但是,材料的感染、粘连、变形等并发症,以及出血引起的血肿、淋巴渗漏引起的乳糜胸、漏气引起的气胸或脓胸,仍有一定的发生率。这些问题表明,目前可用的材料的功能还不能完全满足胸外科医生的需要。在本文中,我们概述了目前在日本批准使用的材料的分类、特性和限制。此外,我们还介绍了新材料开发的最新进展,特别是外科密封剂,包括我们正在共同开发的用于临床应用的阿拉斯加鳕鱼明胶密封剂。在新材料的开发过程中,物理性能的改进,以及不同配方(如液体和片状)的可用性,有望扩大其临床适用性。每种材料的性质和局限性是密切相关的,对两者的透彻理解对于最佳材料选择和适当的临床使用是必不可少的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Current Status and Future Prospects of Covering, Reinforcement, and Sealant Materials in Thoracic Surgery].

Various types of covering materials, reinforcement materials, and sealants with different compositions and structures are available in the field of thoracic surgery. However, complications such as infection, adhesion, and deformation of the materials, as well as hematoma caused by bleeding, chylothorax from lymphatic leakage, and pneumothorax or empyema due to air leaks, still occur at a certain rate. These issues indicate that the functions of currently available materials do not yet fully meet the needs of thoracic surgeons. In this article, we provide an overview of the classification, characteristics, and limitations of materials currently approved for use in Japan. Furthermore, we introduce recent advances in the development of novel materials-particularly surgical sealants-including an Alaska pollock gelatin sealant that we are co-developing for clinical application. In the development of new materials, improvements in physical properties, along with the availability of different formulations-such as liquid and sheet types-are expected to broaden their clinical applicability. The properties and limitations of each material are closely interrelated, and a thorough understanding of both is essential for optimal material selection and appropriate clinical use.

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