Global Medical and Health Communication (GMHC)最新文献

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Clinical Characteristics, Comorbidities, Length of Stay, and Mortality of COVID-19 Patients in RSUD Cideres, Majalengka, West Java 西爪哇Majalengka地区RSUD医院COVID-19患者的临床特征、合并症、住院时间和死亡率
Global Medical and Health Communication (GMHC) Pub Date : 2021-12-31 DOI: 10.29313/gmhc.v9i3.8586
H. Garna, Dika Rifky Fernanda, Gibran Bramasta Dirgavansya, Heru Haerudin, Z. Zulmansyah, Samsudin Surialaga, L. Yuniarti
{"title":"Clinical Characteristics, Comorbidities, Length of Stay, and Mortality of COVID-19 Patients in RSUD Cideres, Majalengka, West Java","authors":"H. Garna, Dika Rifky Fernanda, Gibran Bramasta Dirgavansya, Heru Haerudin, Z. Zulmansyah, Samsudin Surialaga, L. Yuniarti","doi":"10.29313/gmhc.v9i3.8586","DOIUrl":"https://doi.org/10.29313/gmhc.v9i3.8586","url":null,"abstract":"Until now, the world is still facing the COVID-19 pandemic caused by SARS-CoV-2. The number of deaths of COVID-19 patients in Indonesia is quite large when compared to other countries. Clinical manifestations, comorbidities, length of stay, and the mortality of COVID-19 vary widely in each study. This study analyzes clinical characteristics, comorbidities, length of stay, and mortality of COVID-19 patients in RSUD Cideres, Majalengka, West Java. This study is an observational study with total sampling and purposive sampling. Subjects were patients with nasal swabs confirmed SARS-CoV-2 and hospitalized at RSUD Cideres from January to July 2021. Clinical manifestations, comorbidities, length of stay, and mortality of COVID-19 patients aged ≥17 years old, were extracted from medical records. Results showed that the majority of 213 COVID-19 patients were age 41–60 years 114 (53.5%), female 114 (53.5%), with an upper respiratory tract in 207 (97.1%), and shortness of breath in 203 (95.3%) patients. 153 (71.8%) patients had a fever, while headache, diarrhea, and anosmia respectively 49 (23.0%), 19 (8.9%), and 10 (4.6%), respectively. Vital signs were the Glasgow Coma Scale (GCS) normal in 190 (89.2%) patients. Most of patients had respiration rate >20/min in 201 (94.3%), oxygen saturation <90% in 98 (46.0%), and chest x-rays: bronchopneumonia 134 (62.9%) and pneumonia 23 (10.7%). Comorbidities were hypertension, diabetes mellitus, and chronic heart failure in 74 (34.7%), 56 (26.2%), and 46 (11.7%) patients, respectively. The length of stay who died for 1–7 days (22 patients) and 8–14 days (9 patients); means almost all patients (29 of 32) died during the length of stay for 1–14 days. In conclusion, the majority of COVID-19 patients at RSUD Cideres are female, aged 41–60 years, had upper respiratory tract/shortness of breath, GCS normal, saturation oxygen <90%, chest x-rays: bronchopneumonia and pneumonia, comorbidities: hypertension, and length of stay for patients who died 1–7 days. KARAKTERISTIK KLINIS, KOMORBITAS, LAMA RAWAT, DAN MORTALITAS PASIEN COVID-19 DI RSUD CIDERES, MAJALENGKA, JAWA BARATHingga saat ini, dunia masih menghadapi pandemi COVID-19 yang disebabkan oleh SARS-CoV-2. Jumlah kematian pasien COVID-19 di Indonesia cukup besar jika dibanding dengan negara lain. Manifestasi  klinis, komorbid, lama rawat, dan mortalitas pasien COVID-19 sangat bervariasi pada setiap penelitian. Tujuan penelitian ini menganalisis karakteristik klinis, komorbiditas, lama rawat, dan mortalitas pasien COVID-19 di RSUD Cideres, Majalengka, Jawa Barat. Penelitian ini adalah penelitian observasional dengan total sampling dan purposive sampling. Subjek adalah pasien dengan nasal swab terkonfirmasi SARS-CoV-2 dan dirawat di RSUD Cideres periode Januari hingga Juli 2021. Data manifestasi klinis, komorbid, lama rawat, dan mortalitas pasien COVID-19 usia ≥17 diambil dari rekam medik. Hasil menunjukkan bahwa mayoritas 213 pasien COVID-19 berusia 41–60 tahun 114 (53,5%) ","PeriodicalId":178376,"journal":{"name":"Global Medical and Health Communication (GMHC)","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129604728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Factors Associated to Growth Disorder in Children with Thalassemia Major 重度地中海贫血儿童生长障碍相关因素
Global Medical and Health Communication (GMHC) Pub Date : 2021-08-29 DOI: 10.29313/gmhc.v9i2.7674
Nurbaiti Annisaa Soegiharto, Meiyanti Meiyanti
{"title":"Factors Associated to Growth Disorder in Children with Thalassemia Major","authors":"Nurbaiti Annisaa Soegiharto, Meiyanti Meiyanti","doi":"10.29313/gmhc.v9i2.7674","DOIUrl":"https://doi.org/10.29313/gmhc.v9i2.7674","url":null,"abstract":"Growth disorders in short stature are often found in patients with β-thalassemia major. It is caused by several factors such as hypoxia, hemosiderosis, deficiency of nutritional intake, and micronutrient. Disorder in growth will affect the patient's quality of life. This study aims to determine the prevalence of growth disorders and analyze the factors associated with thalassemia child growth disorders. This study used an observational analytic study with a cross-sectional design on 167 patients with β-thalassemia major at the Palang Merah Indonesia Hospital, Bogor, West Java, in October–December 2018. Data was collected using a transfusion compliance questionnaire and the Morisky Medication Adherence Scale (MMAS-8), while growth was assessed using the CDC 2000 height/age curve. Data analysis used SPSS for Windows version 21.0. Of 167 subjects, 86 subjects (51.5%) were not adherent to transfusion, 97 subjects (58.1%) had low consumption of chelation iron, and 146 subjects (87.4%) had growth problems. The results of bivariate data analysis using the chi-square test for transfusion compliance and parental education on growth obtained p=0.000 and p=0.032. Likewise, for compliance with iron chelation consumption and parents' income to growth, the p value=0.000 was obtained. It was concluded that the prevalence of growth disorders was 87.4%, and there was a relationship between transfusion compliance, parental education level, parents' income, and compliance with iron chelation consumption on growth disorders in thalassemia children. FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN GANGGUAN PERTUMBUHAN PADA ANAK TALASEMIA MAYORGangguan pertumbuhan berupa perawakan pendek sering ditemukan pada penderita talasemia β mayor. Hal ini disebabkan oleh beberapa faktor seperti hipoksia, hemosiderosis, kekurangan asupan nutrisi, dan mikonutrien. Gangguan pertumbuhan akan memengaruhi kualitas hidup pasien. Penelitian ini bertujuan mengetahui prevalensi gangguan tumbuh kembang dan menganalisis faktor-faktor yang berhubungan dengan gangguan tumbuh kembang anak talasemia. Penelitian ini menggunakan jenis penelitian observasional analitik dengan desain cross-sectional pada 167 pasien talasemia β mayor di RS Palang Merah Indonesia, Bogor, Jawa Barat pada bulan Oktober–Desember 2018. Pengumpulan data dilakukan dengan menggunakan kuesioner kepatuhan transfusi dan Morisky Medication Adherence Scale (MMAS-8), sedangkan pertumbuhan dinilai menggunakan kurva tinggi/usia CDC 2000. Analisis data menggunakan SPSS for Windows versi 21.0. Dari 167 subjek, 86 subjek (51,5%) tidak patuh pada transfusi, 97 subjek (58,1%) memiliki konsumsi kelasi besi rendah, dan 146 subjek (87,4%) mengalami gangguan pertumbuhan. Hasil analisis data bivariat menggunakan uji chi-square untuk kepatuhan transfusi dan pendidikan orangtua tentang pertumbuhan diperoleh p=0,000 dan p=0,032. Begitu pula untuk kepatuhan konsumsi kelasi besi dan pendapatan orangtua terhadap pertumbuhan diperoleh p=0,000. Disimpulkan ba","PeriodicalId":178376,"journal":{"name":"Global Medical and Health Communication (GMHC)","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127195177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Depression Leads to Physical Inactivity in Patients with Beta-Thalassemia Major 抑郁症导致重度β -地中海贫血患者缺乏运动
Global Medical and Health Communication (GMHC) Pub Date : 2021-08-29 DOI: 10.29313/gmhc.v9i2.7598
Faza Nurul Wardhani, Susanti Dharmmika, H. S. Rathomi
{"title":"Depression Leads to Physical Inactivity in Patients with Beta-Thalassemia Major","authors":"Faza Nurul Wardhani, Susanti Dharmmika, H. S. Rathomi","doi":"10.29313/gmhc.v9i2.7598","DOIUrl":"https://doi.org/10.29313/gmhc.v9i2.7598","url":null,"abstract":"Beta-thalassemia major (BTM) is difficult to treat chronic disease, causing physical and psychological burdens for the patient. Several studies have confirmed a decrease in physical activity and depression in thalassemia patients, but limited studies examine the relationship between these two conditions. This study aims to analyze the relationship between depression and physical activity in BTM patients in Bandung city. It was analytical observational research with a cross-sectional design. Data were collected during September–December 2018 by interviewing 65 patients selected by simple random sampling from 300 thalassemia patients registered at the Association of Parents with Thalassemia Indonesia/Perhimpunan Orangtua Penderita Thalassemia Indonesia (POPTI) Bandung city. The instruments used were the Global Physical Activity Questionnaire (GPAQ) to measure physical activity and the Beck Depression Inventory (BDI) to assess depressive symptoms. Data were analyzed by chi-square test using SPSS for Windows ver. 23.0. The results showed that most BTM patients in Bandung city were depressed (52%) and had low physical activity levels (65%). Furthermore, there was a statistically significant relationship between depression and physical activity in thalassemia patients in Bandung city (p=0.04, p<0.05). Therefore, it can be concluded that BTM patients in Bandung city with depression have lower physical activity. DEPRESI BERDAMPAK PADA AKTIVITAS FISIK YANG RENDAH PADA PASIEN TALASEMIA BETA MAYORTalasemia beta mayor merupakan penyakit kronis yang sulit disembuhkan sehingga menimbulkan beban fisik dan psikologis bagi pasien. Beberapa penelitian telah mengonfirmasi penurunan aktivitas fisik dan depresi pada pasien talasemia, namun studi yang mengkaji hubungan antara kedua kondisi ini masih terbatas jumlahnya. Penelitian ini bertujuan menganalisis hubungan antara kondisi depresi dan tingkat aktivitas fisik pada penderita talasemia beta mayor di Kota Bandung. Desain penelitian bersifat observasional analitik dengan rancangan potong lintang. Pengambilan data dilakukan selama September–Desember 2018 dengan mewawancarai 65 pasien yang dipilih secara simple random sampling dari 300 pasien talasemia yang terdaftar di Perhimpunan Orangtua Penderita Thalassemia Indonesia (POPTI) Kota Bandung. Instrumen yang digunakan adalah Global Physical Activity Questionnaire (GPAQ) untuk mengukur aktivitas fisik dan Beck Depression Inventory (BDI) untuk menilai gejala depresi. Data dianalisis dengan uji chi-square menggunakan SPSS for Windows ver. 23.0. Hasil penelitian menunjukkan mayoritas penderita talasemia beta mayor di Kota Bandung mengalami depresi (52%) dan memiliki tingkat aktivitas fisik rendah (65%). Selanjutnya, terdapat hubungan bermakna secara statistik antara depresi dan aktivitas fisik pada penderita talasemia di Kota Bandung (p=0,04; p<0,05). Oleh karena itu, dapat disimpulkan bahwa penderita talasemia beta mayor di Kota Bandung yang mengalami depresi memiliki ak","PeriodicalId":178376,"journal":{"name":"Global Medical and Health Communication (GMHC)","volume":"252 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131651518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of Patients with Type 2 Diabetes Mellitus in Al-Ihsan Regional General Hospital Al-Ihsan地区总医院2型糖尿病患者的特点
Global Medical and Health Communication (GMHC) Pub Date : 2021-08-29 DOI: 10.29313/gmhc.v9i2.8123
S. A. D. Trusda, W. Purbaningsih, B. Budiman, Siti Salma Nurhaliza Fitriadi
{"title":"Characteristics of Patients with Type 2 Diabetes Mellitus in Al-Ihsan Regional General Hospital","authors":"S. A. D. Trusda, W. Purbaningsih, B. Budiman, Siti Salma Nurhaliza Fitriadi","doi":"10.29313/gmhc.v9i2.8123","DOIUrl":"https://doi.org/10.29313/gmhc.v9i2.8123","url":null,"abstract":"The prevalence of type 2 diabetes mellitus (T2DM) in Indonesia is high, contributing to the fourth mortality rate for non-communicable diseases in Indonesia. The population of T2DM patients spread across all provinces, including West Java, which is the most populous province in Indonesia. One of the referral hospitals in West Java is Al-Ihsan Regional General Hospital in Bandung regency. The purpose of this study was to describe the characteristics of T2DM patients who came to Al-Ihsan Regional General Hospital according to age, gender, and comorbidities parameters. It was a descriptive cross-sectional study using secondary data from medical records of T2DM patients between January 2017 and November 2020. The results were the highest prevalence and incidence of T2DM were in 2017 with as many as 5,051 and 653 respectively; the highest gender each year was female, range between 584–3,333, with the highest male: female ratio of 1:2 in 2017; the age group with the highest prevalence was 55–65 years which was 3,468 (39.53%); and top five comorbidities were hypertension (35.68%), cataracts (6.01%), osteoarthritis (3.58%), pulmonary tuberculosis (2.92%) and dyspepsia (2.91%). This study concluded that the prevalence and incidence of T2DM in Al-Ihsan Regional General Hospital were high, with the predominant female patients, elderly, and comorbid hypertension. KARAKTERISTIK PASIEN DIABETES MELITUS TIPE 2 DI RSUD AL-IHSANAngka kejadian diabetes melitus tipe 2 (DMT2) di Indonesia cukup tinggi, menyumbangkan angka kematian keempat penyakit tidak menular di Indonesia. Penderita DMT2 tersebar di seluruh provinsi, termasuk Jawa Barat yang merupakan provinsi terpadat di Indonesia. Salah satu rumah sakit rujukan di Jawa Barat adalah RSUD Al-Ihsan di Kabupaten Bandung. Tujuan penelitian ini adalah menggambarkan karakteristik pasien DMT2 yang datang ke RSUD Al-Ihsan dilihat dari usia, jenis kelamin, dan komorbid. Penelitian ini merupakan penelitian deskriptif cross-sectional menggunakan data sekunder berupa rekam medis pasien DMT2 periode Januari 2017 hingga November 2020. Didapatkan bahwa prevalensi dan insidensi DMT2 tertinggi pada tahun 2017 sebesar 5.051 dan 653 masing-masing; jenis kelamin terbanyak pada setiap tahun adalah wanita sebesar 584–3.333 dengan rasio pria:wanita tertinggi 1:2 pada tahun 2017; kelompok usia dengan prevalensi tertinggi adalah 55–65 tahun sebesar 3.468 (39,53%); dan lima komorbid tertinggi adalah hipertensi (35,68%), katarak (6,01%), osteoartritis (3,58%), tuberkulosis paru (2,92%), dan dispepsia (2,91%). Simpulan penelitian ini adalah prevalensi dan insidensi DMT2 di RSUD Al-Ihsan tinggi dengan pasien terbanyak wanita, lanjut usia, dan komorbid hipertensi.","PeriodicalId":178376,"journal":{"name":"Global Medical and Health Communication (GMHC)","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132552514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stakeholder Perception towards the Implementation of National Health Insurance Program 利益相关者对实施国家健康保险计划的看法
Global Medical and Health Communication (GMHC) Pub Date : 2021-08-29 DOI: 10.29313/gmhc.v9i2.8022
Y. Susanti, Tita Barriah Siddiq, S. N. Irasanti, R. Perdana, Yusuf Heriady
{"title":"Stakeholder Perception towards the Implementation of National Health Insurance Program","authors":"Y. Susanti, Tita Barriah Siddiq, S. N. Irasanti, R. Perdana, Yusuf Heriady","doi":"10.29313/gmhc.v9i2.8022","DOIUrl":"https://doi.org/10.29313/gmhc.v9i2.8022","url":null,"abstract":"Indonesian National Health Insurance (NHI) is a social protection program that ensures the fulfillment of basic needs for proper health by implementing a quality and cost control system. There are still differences in perceptions and complaints felt by patients regarding the implementation of the NHI program. The purpose of this study was to evaluate the implementation of the NHI program based on the perception of all stakeholders in the aspect of health equity, quality of service, and health financing. Quantitative research methods with survey techniques on 204 respondents were selected by stratified random sampling in Al-Ihsan Regional General Hospital West Java Province from January to May 2021. The data were analyzed by using the Kruskal-Wallis test and Mann-Whitney U test on the perception of the stakeholder groups. The results showed that the aspects of health equity, service quality, and health financing on the implementation of the NHI program were in a good category. The increase in Healthcare and Social Security Agency (HSSA) insurance premium was considered the lowest aspect. There were significant differences in the perception of stakeholder groups on the aspects of health equity, service quality, and health financing. There were significant differences in perceptions of health equity based on the ages groups and in perceptions of health financing based on income. This indicates that stakeholders' perceptions of the NHI program affected some conditions, including roles in services, ages, and income. PERSEPSI STAKEHOLDER TERHADAP IMPLEMENTASI PROGRAM JAMINAN KESEHATAN NASIONALJaminan Kesehatan Nasional (JKN) merupakan program perlindungan sosial yang menjamin pemenuhan kebutuhan dasar kesehatan yang layak melalui penerapan sistem kendali mutu dan biaya. Masih terdapat perbedaan persepsi dan keluhan yang dirasakan pasien terhadap pelaksanaan program JKN. Tujuan penelitian ini mengevaluasi pelaksanaan program JKN berdasar atas persepsi seluruh stakeholder pada aspek health equity (pemerataan), mutu layanan, dan pembiayaan kesehatan. Metode penelitian kuantitatif dengan teknik survei pada 204 responden yang dipilih secara stratified random sampling di RSUD Al-Ihsan Provinsi Jawa Barat periode Januari−Mei 2021. Analisis data menggunakan Uji Kruskal-Wallis dan Mann-Whitney U terhadap persepsi kelompok stakeholder. Hasil penelitian menunjukkan bahwa aspek health equity, mutu layanan, dan pembiayaan kesehatan pada implementasi program JKN berada dalam kategori baik. Kenaikan premi asuransi BPJS Kesehatan dinilai paling rendah. Terdapat perbedaan signifikan persepsi antara kelompok stakeholder pada aspek health equity, mutu layanan, dan pembiayaan kesehatan. Terdapat perbedaan signifikan persepsi terhadap health equity berdasar atas kelompok usia dan persepsi pada aspek pembiayaan kesehatan berdasar atas pendapatan. Hal ini menunjukkan bahwa persepsi stakeholder terhadap program JKN dipengaruhi beberapa kondisi, antara lain peran dalam layanan","PeriodicalId":178376,"journal":{"name":"Global Medical and Health Communication (GMHC)","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127265131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thirdhand Smoke Exposure Affects Mice Pancreas Microstructure 三手烟暴露对小鼠胰腺微观结构的影响
Global Medical and Health Communication (GMHC) Pub Date : 2021-08-29 DOI: 10.29313/gmhc.v9i2.8039
E. R. Indrasari, A. R. Furqaani, L. H. Siswanti, Ihsan Muhammad Nauval, Putra Zam Zam Rachmatullah
{"title":"Thirdhand Smoke Exposure Affects Mice Pancreas Microstructure","authors":"E. R. Indrasari, A. R. Furqaani, L. H. Siswanti, Ihsan Muhammad Nauval, Putra Zam Zam Rachmatullah","doi":"10.29313/gmhc.v9i2.8039","DOIUrl":"https://doi.org/10.29313/gmhc.v9i2.8039","url":null,"abstract":"Cigarette residue toxins can accumulate in the body, including the pancreas, which potentially reduces pancreas function. In addition, the active compounds in cigarettes are reporting to interfere with an elevation of reactive oxygen species, leading to disruption of pancreatic microstructures. Furthermore, pancreatic cell dysfunction is responsible for developing diabetes mellitus disease. The objective of this study was to analyze the effect of thirdhand smoke exposure on mice pancreatic microstructure image. It was an in vivo laboratory experimental study with a completely randomized design at the Medical Biology Laboratory of the Universitas Islam Bandung from November 2020–June 2021. The subjects were 20 adult male mice aged 8–10 weeks, weighing 25–30 grams, in good health condition, and randomly divided into two groups (control group and treatment group exposed to thirdhand cigarette smoke for four weeks). After the completion of the exposure period, pancreatic cells isolation was performing. The parameters observed in this study were the number and diameter islet of Langerhans. Data analysis used the independent t test parametric (α=5%). The results showed that the number and diameter islet of Langerhans in the treated group were significantly lower than the control group (p<0.05). The average number in the control group was 9.40±3.20, while in the treatment group was 4.90±2.74 (28% smaller). The average diameter of control was 225.96±50.15 mm, while treatment was 162±49.68 mm (50% lower). In conclusion, thirdhand smoke exposure alters the pancreas microstructure. The toxic compounds on thirdhand cigarette smoke are involving in generating an elevation of free radical levels, depletion of antioxidants, and alteration of signal transduction resulted in acceleration of apoptosis rate of the islet of Langerhans, especially pancreatic β-cells. PENGARUH PAPARAN ASAP ROKOK TERSIER PADA GAMBARAN MIKROSTRUKTUR PANKREAS MENCITToksik residu rokok dapat terakumulasi pada tubuh, termasuk pankeas sehingga dapat menurunkan fungsi pankreas. Selain itu, senyawa aktif dalam rokok dilaporkan meningkatkan radikal bebas yang menyebabkan kerusakan mikrostruktur pankreas. Selanjutnya, disfungsi sel pankreas meningkatkan risiko diabetes melitus. Penelitian ini bertujuan menganalisis pengaruh asap rokok tersier terhadap gambaran mikrostruktur pankreas mencit. Penelitian ini merupakan penelitian eksperimental laboratorium in vivo dengan rancangan acak lengkap di Laboratorium Biologi Medik Universitas Islam Bandung periode November 2020–Juni 2021. Subjek penelitian adalah 20 mencit jantan dewasa berumur 8–10 minggu, bobot 25–30 gram, kondisi sehat, dan dibagi secara acak menjadi dua kelompok (kelompok kontrol dan kelompok perlakuan yang mendapat paparan asap rokok tersier selama empat minggu). Setelah periode pemberian paparan selesai, dilakukan isolasi sel pankreas. Parameter yang diamati dalam penelitian ini adalah jumlah dan diameter pulau Langerhans (islet of L","PeriodicalId":178376,"journal":{"name":"Global Medical and Health Communication (GMHC)","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134105287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of Health Knowledge of Lung Function in Predicting Respiratory Disorders in Smokers 肺功能健康知识在预测吸烟者呼吸系统疾病中的作用
Global Medical and Health Communication (GMHC) Pub Date : 2021-08-29 DOI: 10.29313/gmhc.v9i2.7673
Amelia Lorensia, R. V. Suryadinata, Lalita Tirsa
{"title":"Identification of Health Knowledge of Lung Function in Predicting Respiratory Disorders in Smokers","authors":"Amelia Lorensia, R. V. Suryadinata, Lalita Tirsa","doi":"10.29313/gmhc.v9i2.7673","DOIUrl":"https://doi.org/10.29313/gmhc.v9i2.7673","url":null,"abstract":"Chronic obstructive pulmonary disease (COPD) is a high risk for active smokers. Early assessment of the condition of lung function is needed to prevent a decrease in lung function. Knowledge of self-management that determines lung health. The purpose of this study was to determine the knowledge of lung function health in predicting respiratory disorders. The study design was a case-control from August 2018 to January 2019. Data was collected through a questionnaire, namely a lung health knowledge questionnaire consisting of categories: risk factors, symptoms, and therapy for respiratory disorders. The research sample was adult men who work in the transportation sector in Surabaya city using purposive sampling. Data analysis using chi-square. The data obtained were 300 people, consisting of 126 people without lung function disorders and 174 people with pulmonary function disorders. The risk factor knowledge category showed a significant difference (p=0.000) between the group, with the most disorders at the low knowledge level (42.0%). The symptom knowledge category showed a significant difference (p=0.000) between groups, and most of the groups with disorders were at a low knowledge level (55.8%). The category of knowledge of respiratory symptoms showed a significant difference (p=0.000) between groups, with the knowledge level in both of them mostly at a sufficient level. Therefore, low lung function health knowledge reflects low lung function conditions. IDENTIFIKASI PENGETAHUAN KESEHATAN FUNGSI PARU DALAM MEMPREDIKSI GANGGUAN PERNAPASAN PADA PEROKOKPenyakit paru obstruktif kronik (PPOK) berisiko tinggi dialami oleh perokok aktif. Pengkajian dini terhadap kondisi fungsi paru diperlukan untuk mencegah penurunan fungsi paru. Pengetahuan tentang manajemen diri yang menentukan kesehatan paru. Tujuan penelitian ini adalah mengetahui pengetahuan kesehatan fungsi paru dalam memprediksi gangguan pernapasan. Desain penelitian adalah case-control dari Agustus 2018 hingga Januari 2019. Pengumpulan data dilakukan melalui kuesioner, yaitu kuesioner pengetahuan kesehatan paru yang terdiri atas kategori: faktor risiko, gejala, dan terapi gangguan pernapasan. Sampel penelitian adalah laki-laki dewasa yang bekerja di sektor transportasi di Kota Surabaya dengan menggunakan purposive sampling. Analisis data menggunakan chi-square. Data yang diperoleh sebanyak 300 orang, terdiri atas 126 orang tanpa gangguan fungsi paru dan 174 orang dengan gangguan fungsi paru. Kategori pengetahuan faktor risiko menunjukkan perbedaan yang bermakna (p=0,000) antarkelompok dengan gangguan terbanyak pada pengetahuan tingkat rendah (42,0%). Kategori pengetahuan gejala menunjukkan perbedaan yang bermakna (p=0,000) antarkelompok dan sebagian besar kelompok dengan gangguan berada pada pengetahuan tingkat rendah (55,8%). Kategori pengetahuan gejala pernapasan menunjukkan perbedaan yang bermakna (p=0,000) antarkelompok dengan tingkat pengetahuan keduanya sebagian besar pada tingkat cukup. ","PeriodicalId":178376,"journal":{"name":"Global Medical and Health Communication (GMHC)","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128391455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Association of Chest X-Rays Features with the Length of Stay in Suspected COVID-19 Status 胸部x线特征与疑似COVID-19患者住院时间的关系
Global Medical and Health Communication (GMHC) Pub Date : 2021-08-29 DOI: 10.29313/gmhc.v9i2.7905
Z. Zulmansyah, G. Nugraha, D. Agustian, D. A. Gurnida
{"title":"Association of Chest X-Rays Features with the Length of Stay in Suspected COVID-19 Status","authors":"Z. Zulmansyah, G. Nugraha, D. Agustian, D. A. Gurnida","doi":"10.29313/gmhc.v9i2.7905","DOIUrl":"https://doi.org/10.29313/gmhc.v9i2.7905","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is a new type of respiratory infection that first emerged in December 2019 in Wuhan, Hubei, China. COVID-19 is caused by a new variant of virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Examining the chest x-rays is one technique to diagnose COVID-19. This study aims to determine the association of chest x-rays features in suspected COVID-19 patients with the length of stay at Al-Ihsan Regional General Hospital West Java Province and Banten Regional General Hospital in June–November 2020. The subject was 29 COVID-19 people were confirmed, whereas 31 people were not. The statistical analysis used Pearson correlation and multi-linear regression. This study found that tuberculosis had a strong association with length of stay (p value=0.048, association=0.4), and also there is a robust association between bilateral pneumonia and duration of stay (p value=0.028, association=0.873). A linear regression model discovery of TB photo on the subject raises the treatment by 0.5867 days. In addition, the discovery of bilateral pneumonia increases the length of stay of treatment by 0.32218 days more than the discovery of unilateral pneumonia. In general, tuberculosis, bacterial pneumonia, viral pneumonia, and bilateral pneumonia together affected the outcome of length of stay of patients with suspected COVID-19. ASOSIASI GAMBARAN RONTGEN TORAKS DENGAN LAMA RAWAT PADA PASIEN SUSPEK COVID-19Coronavirus disease 2019 (COVID-19) adalah jenis infeksi saluran pernapasan baru yang pertama kali mewabah pada Desember 2019 di Wuhan, Hubei, Cina. COVID-19 disebabkan oleh varian virus baru yang disebut severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Pemeriksaan rontgen toraks merupakan salah satu teknik mendiagnosis COVID-19. Penelitian ini bertujuan mengetahui asosiasi gambaran rontgent toraks pada pasien suspek COVID-19 dengan lama rawat inap di RSUD Al-Ihsan Provinsi Jawa Barat dan RSUD Banten pada Juni–November 2020. Subjek penelitian adalah 29 orang terkonfirmasi COVID-19 dan 31 orang tidak. Analisis statistik menggunakan korelasi Pearson dan regresi multilinier. Penelitian ini menemukan bahwa tuberkulosis memiliki hubungan yang kuat dengan lama perawatan (p=0,048; asosiasi=0,4) dan juga terdapat hubungan yang kuat antara pneumonia bilateral dan lama perawatan (p=0,028; asosiasi=0,873). Penemuan model regresi linier foto TB pada subjek meningkatkan risiko perawatan 0,5867 hari lebih lama. Selain itu, penemuan pneumonia bilateral meningkatkan risiko perawatan 0,32218 hari lebih lama dibanding dengan penemuan pneumonia unilateral. Secara umum, tuberkulosis, pneumonia bakteri, pneumonia viral, dan pneumonia bilateral secara bersama-sama berpengaruh terhadap luaran lama rawat inap pasien suspek COVID-19.","PeriodicalId":178376,"journal":{"name":"Global Medical and Health Communication (GMHC)","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129793769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Relationship between Vitamin B9 (Folic Acid), Vitamin B12 (Cobalamin), and Peripheral Neuropathy in Children with Beta-Thalassemia Major 重度β -地中海贫血儿童维生素B9(叶酸)、维生素B12(钴胺素)与周围神经病变的关系
Global Medical and Health Communication (GMHC) Pub Date : 1900-01-01 DOI: 10.29313/gmhc.v9i2.8106
U. Gamayani, Titin Junaidi, N. Lailiyya, Nur Suryawan, N. Sekarwana
{"title":"Relationship between Vitamin B9 (Folic Acid), Vitamin B12 (Cobalamin), and Peripheral Neuropathy in Children with Beta-Thalassemia Major","authors":"U. Gamayani, Titin Junaidi, N. Lailiyya, Nur Suryawan, N. Sekarwana","doi":"10.29313/gmhc.v9i2.8106","DOIUrl":"https://doi.org/10.29313/gmhc.v9i2.8106","url":null,"abstract":"Vitamin B9 (folic acid) and B12 (cobalamin) are essential vitamins that play roles in the process of hematopoiesis and maintaining the function of peripheral nerves. Therefore, these deficiencies may create a risk for peripheral neuropathy in beta-thalassemia major patients. The purpose of this study is to determine the relationship between vitamin B9 level, vitamin B12 level, and peripheral neuropathy in beta-thalassemia major children. It was an observational analytical study with a case-control design has been conducted at Dr. Hasan Sadikin General Hospital Bandung, Indonesia, in May–July 2019. There were 47 beta-thalassemia major children with peripheral neuropathy (case) and 41 healthy children (control). All subjects completed a general demographic questionnaire, underwent neurological examination, and were tested for vitamin B9 and B12 serum levels. Data were then analyzed using the unpaired t test to compare the vitamin levels between both groups and Spearman’s rank correlation test to investigate the correlation between vitamin levels and the number of affected nerves in the case group. Comparison of folic acid levels in the case group (21.52±6.22 ng/mL) and the control group (23.81±7.51 ng/mL) showed no significant difference (p=0.19). In contrast, cobalamin in the case group (288.57±168.61 ng/mL) and the control group (385.95±197.48 ng/mL) showed a significant difference (p=0.01). In addition, there was a moderate correlation (p=0.004, r=0.41) between folic acid level and the number of motoric nerves affected in the case group. In conclusion, cobalamin level correlates with peripheral neuropathy in beta-thalassemia major patients, and folic acid level correlates with the number of affected nerves, especially motoric nerves. HUBUNGAN ANTARA VITAMIN B9 (ASAM FOLAT), VITAMIN B12 (KOBALAMIN), DAN NEUROPATI PERIFER PADA ANAK DENGAN TALASEMIA BETA MAYORVitamin B9 (asam folat) dan B12 (kobalamin) merupakan vitamin esensial yang berperan dalam proses hematopoiesis dan menjaga fungsi saraf tepi. Defisiensi vitamin ini dapat menimbulkan risiko neuropati perifer pada pasien talasemia beta mayor. Tujuan penelitian ini mengetahui hubungan antara kadar vitamin B9, vitamin B12, dan neuropati perifer pada anak talasemia beta mayor. Metode penelitian ini adalah analitik observasional dengan rancangan studi kasus kontrol yang dilakukan di RSUP Dr. Hasan Sadikin Bandung, Indonesia pada Mei–Juli 2019. Terdapat 47 anak talasemia beta mayor dengan neuropati perifer (kelompok kasus) dan 41 anak sehat (kelompok kontrol). Seluruh subjek penelitian mengisi kuesioner demografi umum, menjalani pemeriksaan fisis neurologis, serta dilakukan tes kadar vitamin B9 dan B12 serum. Uji t test tidak berpasangan digunakan untuk membandingkan kadar vitamin pada kedua kelompok dan uji korelasi Spearman untuk membandingkan kadar kedua vitamin tersebut dengan jumlah saraf yang terkena pada kelompok kasus. Perbandingan kadar asam folat kelompok kasus (21,52±6,22 ng/mL) dan kelo","PeriodicalId":178376,"journal":{"name":"Global Medical and Health Communication (GMHC)","volume":"105 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133103919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of Labor Camera on the Duration of the Second Stage Labor in Primipara 产程相机对初产妇第二产程持续时间的影响
Global Medical and Health Communication (GMHC) Pub Date : 1900-01-01 DOI: 10.29313/gmhc.v9i2.6993
Yetti Purnama, Kurnia Dewiani, Linda Yusanti
{"title":"Effect of Labor Camera on the Duration of the Second Stage Labor in Primipara","authors":"Yetti Purnama, Kurnia Dewiani, Linda Yusanti","doi":"10.29313/gmhc.v9i2.6993","DOIUrl":"https://doi.org/10.29313/gmhc.v9i2.6993","url":null,"abstract":"Fear and anxiety due to severe labor pains could also lead to prolonged labor. The efforts made to accelerate the second stage labor process are by providing emotional support with the support of a labor camera. The mother is allowed to observe the development state of her baby's head through video on a tablet or laptop screen. Furthermore, the mother's emotional level becomes more provoked and motivated to strain the labor process faster. This study aims to determine the effect of the labor cameras on the second state duration in primiparous. The design of this study was a posttest-only control group design experiment with a total sample of 30 primiparous of the second stage at independent midwife practice in Bengkulu city in November–December 2020. Each group consisted of 15 for treatment (with labor cameras) and 15 for control (without labor cameras)—the assessment of the labor duration by counting the labor time in seconds during the second state. The statistical results using the t test and chi-square test analysis showed that the intervention group's labor duration (1,393.3 seconds) was shorter than the control group's (2,340.6 seconds). The mean difference in the delivery time was 947.3 seconds or 15.7 minutes faster in the intervention group than in the control group. In conclusion, using a labor camera on the labor duration of the second stage in primiparous mothers is an effect of using a labor camera. PENGARUH KAMERA PERSALINAN TERHADAP DURASI PERSALINAN KALA II PADA PRIMIPARARasa takut dan cemas akibat nyeri persalinan yang berat juga dapat menyebabkan partus lama. Salah satu upaya yang dilakukan untuk mempercepat proses kala II persalinan adalah memberikan dukungan emosional dengan bantuan kamera persalinan. Ibu diberi kesempatan untuk melihat perkembangan pengeluaran kepala bayinya melalui video pada layar tablet atau laptop sehingga tingkat emosional ibu menjadi lebih terbangun dan termotivasi untuk mempercepat proses persalinan. Penelitian ini bertujuan mengetahui pengaruh kamera persalinan terhadap durasi persalinan kala II pada primipara. Desain penelitian adalah eksperimen posttest-only control group design dengan jumlah sampel 30 primipara kala II di bidan praktik mandiri Kota Bengkulu pada November–Desember 2020. Tiap-tiap kelompok berjumlah 15 untuk kelompok perlakuan (menggunakan kamera persalinan) dan 15 untuk kontrol (tidak menggunakan kamera persalinan). Penilaian durasi persalinan dengan menghitung detik selama kala II berlangsung. Pengujian statistik menggunakan analisis uji t dan uji chi-square menunjukkan bahwa durasi persalinan kelompok perlakuan (1.393,3 detik) lebih singkat daripada kelompok kontrol (2.340,6 detik). Selisih perbedaan waktu persalinan rerata selama 947,3 detik atau 15,7 menit lebih cepat pada kelompok intervensi dibanding dengan kelompok kontrol. Simpulan, terdapat pengaruh penggunaan kamera persalinan terhadap durasi persalinan kala II pada ibu primipara.","PeriodicalId":178376,"journal":{"name":"Global Medical and Health Communication (GMHC)","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127373147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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