KONA Powder and Particle Journal最新文献_第4页

Verification of Polyhedral DEM with Laboratory Grinding Mill Experiments 多面体DEM的室内磨机实验验证

IF 4.1 4区材料科学

KONA Powder and Particle Journal Pub Date : 2022-01-10 DOI: 10.14356/KONA.2022013

Alberto M. Puga, N. Govender, R. Rajamani

{"title":"Verification of Polyhedral DEM with Laboratory Grinding Mill Experiments","authors":"Alberto M. Puga, N. Govender, R. Rajamani","doi":"10.14356/KONA.2022013","DOIUrl":"https://doi.org/10.14356/KONA.2022013","url":null,"abstract":"The simulation of grinding mills with the discrete element method (DEM) has been advancing. First, it emerged as a method for studying charge motion with spherical balls and predicting the power draw of the mill. Subsequently, studies on liner wear, charge motion with ellipsoidal and polyhedral shaped particles simulated with three dimensional DEM followed. Further, the impact energy spectra computed in the DEM algorithm is leading to the development of models for the breakage of brittle particles in mills. The core elements in such simulations are the shape of particles in the mill charge and the power draw of the mill due to operating variables. To advance the field, we present a set of experimental data and the corresponding DEM validation results for a 90 × 13 cm mill. The DEM algorithm uses the volume-overlap method which is more realistic for multifaceted irregular particle collisions. Further, we use the scanned shape of the rock media and multifaceted spherical shape for the grinding media to represent as close as possible the actual charge in the mill. First, we present DEM validation for spherical grinding media-only experiments, rock-only experiments, and a mixture of spherical grinding media and rocks, as well as aluminum cubes only to represent the theme of particle shape. Finally, a discussion of the contact mechanics parameters in the four modes of experiments is given. Since the feed ore to plant scale mills can vary in shape, mill simulations with scanned shape of typical particles are the future for more accurate results.","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81855839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Carbonation Kinetics of Fine CaO Particles in a Sound-Assisted Fluidized Bed for Thermochemical Energy Storage 声助流化床热化学储能中细小CaO颗粒的碳化动力学

IF 4.1 4区材料科学

KONA Powder and Particle Journal Pub Date : 2022-01-10 DOI: 10.14356/KONA.2022007

F. Raganati, P. Ammendola

{"title":"Carbonation Kinetics of Fine CaO Particles in a Sound-Assisted Fluidized Bed for Thermochemical Energy Storage","authors":"F. Raganati, P. Ammendola","doi":"10.14356/KONA.2022007","DOIUrl":"https://doi.org/10.14356/KONA.2022007","url":null,"abstract":"The calcium-looping process, relying on the reversible calcination/carbonation of CaCO 3 , is one of the most promising solution to perform thermochemical energy storage (TCES) for concentrating solar power (CSP) plants. Indeed, CaO precursors such as limestone can rely on the high energy density, low cost, large availability and nontoxicity. In this work, the study of the sound-assisted carbonation of fine CaO particles (< 50 μm) for TCES-CSP has been furthered. In particular, a kinetic study has been performed to analyse the effect of the particular carbonation conditions to be used in TCES-CSP applications, i.e. involving carbonation under high CO 2 partial pressure and at high temperature. All the experimental tests have been performed in a lab-scale sound-assisted fluidized bed reactor applying high intensity acoustic field with proper frequency (150 dB–120 Hz). The carbonation kinetics has been analysed by applying a simple kinetic model, able to properly describe the fast (under kinetic control) and slow (under diffusion control) stage of the of the reaction. In particular, the reaction rate, the intrinsic carbonation kinetic constant and the characteristic product layer thickness have been evaluated, also highlighting their dependence on the temperature between 800 and 845 °C; a value of 49 kJ mol –1 has been obtained for the activation energy. Finally, a good agreement between the conversion-time profiles, evaluated from the applied kinetic models, and the experimental data has been obtained.","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84805471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Continuous Synthesis of Precision Gold Nanoparticles Using a Flow Reactor 用流动反应器连续合成精密金纳米颗粒

IF 4.1 4区材料科学

KONA Powder and Particle Journal Pub Date : 2022-01-10 DOI: 10.14356/KONA.2022011

Jiaqi Dong, J. Lau, S. Svoronos, B. Moudgil

引用次数: 3

Advances in the Rheological Characterization of Slurries of Elongated Particles 细长颗粒浆料流变特性研究进展

IF 4.1 4区材料科学

KONA Powder and Particle Journal Pub Date : 2022-01-10 DOI: 10.14356/KONA.2022009

Saif Shaikh, Scott Strednak, Jason E. Butler

{"title":"Advances in the Rheological Characterization of Slurries of Elongated Particles","authors":"Saif Shaikh, Scott Strednak, Jason E. Butler","doi":"10.14356/KONA.2022009","DOIUrl":"https://doi.org/10.14356/KONA.2022009","url":null,"abstract":"Inherent challenges regarding the rheological characterization of slurries of elongated particles have necessitated the development of alternatives to standardized rheometers. These methods of measurement, and the associated advances in the quantification of shear and normal stress measurements, are described. Also, recent advances in modeling and predictive capabilities are summarized. During shearing flows, confinement substantially influences the orientation distribution of the particles; this change in the microstructure impacts the rheology, even as the smallest confining dimension exceeds seven particle lengths. The slow development of the orientation distributions renders additional difficulties in evaluating the rheology. Achievements of the measurement methods include a universal shear viscosity as a function of concentration for a wide range of particle lengths to diameters (aspect ratios). The jamming limit (divergence of the viscosity with concentration) of the suspensions has been also shown to scale differently than for spheres. More general dynamics of the suspensions and the additional needs for measurement improvements are discussed.","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88923892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

High Performance Nickel Based Electrodes in State-of-the-Art Lithium-ion Batteries: Morphological Perspectives 高性能镍基电极在最先进的锂离子电池:形态学的观点

IF 4.1 4区材料科学

KONA Powder and Particle Journal Pub Date : 2022-01-10 DOI: 10.14356/kona.2022015

A. Purwanto, S. S. Nisa, I. P. Lestari, M. Ikhsanudin, C. Yudha, H. Widiyandari

引用次数: 4

Contribution of Particle Design Research to the Development of Patient-Centric Dosage Forms 粒子设计研究对以病人为中心的剂型发展的贡献

IF 4.1 4区材料科学

KONA Powder and Particle Journal Pub Date : 2022-01-10 DOI: 10.14356/kona.2022017

H. Takeuchi

{"title":"Contribution of Particle Design Research to the Development of Patient-Centric Dosage Forms","authors":"H. Takeuchi","doi":"10.14356/kona.2022017","DOIUrl":"https://doi.org/10.14356/kona.2022017","url":null,"abstract":"A variety of dosage forms have been developed in order to achieve effective and safe drug delivery in topical or systemic drug administrations. In this review, formulation research and process issues related to a popular oral dosage form, the tablet, are introduced. Research on oral dosage forms, including orally disintegrating tablets (ODTs) and films (ODFs), which have recently been developed with an aim toward more patient-centric drug therapy, is also introduced. Another trend in recent drug therapy is an increase in the number of large bioactive molecules among the newly developed active pharmaceutical ingredients (APIs). To design dosage forms for these APIs, novel dosage form design and administration routes are required. For this purpose, we have tried to effectively use the polymer-coated liposomes in oral, pulmonary and ophthalmic administration. For example, suitable polymers were introduced for the design of specific administration routes, such as mucoadhesive liposomes for oral administration. The key point in these researches is the particle design for the component particles of final dosage forms, both in the case of coarse powder particle design for formulating solid dosage forms and in the case of colloidal particle design, such as the design of liposomes for peptide drug delivery.","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80219202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Review of Distribution and Segregation Mechanisms of Dockage and Foreign Materials in On-Farm Grain Silos for Central Spout Loading 农业粮食仓中央喷口装填堆积物与外来物分布与分离机制研究进展

IF 4.1 4区材料科学

KONA Powder and Particle Journal Pub Date : 2022-01-10 DOI: 10.14356/kona.2022014

F. Jian

引用次数: 4

General Information 一般信息

IF 4.1 4区材料科学

KONA Powder and Particle Journal Pub Date : 2022-01-10 DOI: 10.14356/kona.2022025

引用次数: 0

The Development of Thin-film Freezing and Its Application to Improve Delivery of Biologics as Dry Powder Aerosols 薄膜冷冻技术的发展及其在改善干粉气溶胶生物制剂输送中的应用

IF 4.1 4区材料科学

KONA Powder and Particle Journal Pub Date : 2022-01-10 DOI: 10.14356/KONA.2022010

Stephanie Hufnagel, Sawittree Sahakijpijarn, Chaeho Moon, Z. Cui, R. Williams

{"title":"The Development of Thin-film Freezing and Its Application to Improve Delivery of Biologics as Dry Powder Aerosols","authors":"Stephanie Hufnagel, Sawittree Sahakijpijarn, Chaeho Moon, Z. Cui, R. Williams","doi":"10.14356/KONA.2022010","DOIUrl":"https://doi.org/10.14356/KONA.2022010","url":null,"abstract":"While the formulation of pharmaceuticals as liquids is common practice, powders are associated with enhanced stability, avoidance of the cold chain, lower dosing requirements, and more convenient administration. These are particularly critical for proteins, as they are expensive and complicated to manufacture. Powders also have improved aerosol properties for pulmonary delivery. Conventional techniques for formulating powders include spray-drying, shelf freeze-drying, spray freeze-drying, and spray freezing into liquid, but they produce powders with poor aerosol performance and/or activity due to suboptimal powder properties. Thin-film freezing (TFF) is a new cryogenic technique that can engineer highly porous, brittle, powder matrices with excellent aerosol performance properties and stability. Herein, we describe TFF in comparison to other cryogenic techniques. Physical properties of TFF powders such as morphology, moisture sorption, stability, solubility, and dissolution, as well as aerosol properties are discussed. In addition, factors that significantly affect the physical and aerosol properties of dry powders prepared by TFF, such as solids content, drug loading, solvent system, excipient, and dry powder delivery device, are analyzed. Finally, we provide evidence supporting the applicability of using TFF to prepare dry powder formulations of protein-based pharmaceuticals, enabling their cold chain-free storage as well as efficient pulmonary delivery.","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75417937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

The Sevilla Powder Tester: A Tool for Measuring the Flow Properties of Cohesive Powders at High Temperatures 塞维利亚粉末测试仪:在高温下测量粘性粉末流动特性的工具

IF 4.1 4区材料科学

KONA Powder and Particle Journal Pub Date : 2022-01-10 DOI: 10.14356/KONA.2022008

R. Gannoun, J. Ebri, A. Pérez, J. Valverde

引用次数: 0