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Outstanding Contributions to Aerosol Pulmonary Drug Delivery. 对气溶胶肺给药的杰出贡献。
IF 2.7 4区 材料科学
KONA Powder and Particle Journal Pub Date : 2026-01-10 Epub Date: 2025-06-21 DOI: 10.14356/kona.2026011
Anthony J Hickey, Erik S Pena, Sara E Maloney Norcross
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引用次数: 0
Discrete Particle Modeling and Simulation of Granular Flow—Pioneering Development of Numerical Prediction of Granular Flow and Fluid–Solid Multiphase Flow— 颗粒流动的离散颗粒建模与模拟-颗粒流动与流固多相流数值预测的开创性发展
4区 材料科学
KONA Powder and Particle Journal Pub Date : 2025-07-28 DOI: 10.14356/kona.2026015
Toshitsugu Tanaka, Toshihiro Kawaguchi, Takuya Tsuji, Kimiaki Washino
{"title":"Discrete Particle Modeling and Simulation of Granular Flow—Pioneering Development of Numerical Prediction of Granular Flow and Fluid–Solid Multiphase Flow—","authors":"Toshitsugu Tanaka, Toshihiro Kawaguchi, Takuya Tsuji, Kimiaki Washino","doi":"10.14356/kona.2026015","DOIUrl":"https://doi.org/10.14356/kona.2026015","url":null,"abstract":"Discrete Element Method (DEM) was proposed by Cundall and Strack (1979) and gained traction in the field of powder engineering during the late 1980s. In the 1990s, various applications of DEM were conducted in the powder technology field, and the capability of DEM for predicting powder behavior was acknowledged. In the 2000s and 2010s, advancements in computing technology and the availability of general-purpose software led to the widespread adoption of numerical simulation as a prevalent tool in industrial applications. The authors have been engaged in discrete particle modeling of gas–solid two-phase flows and the development of DEM–CFD models for the numerical analysis of both dense gas–solid two-phase flows and gas–liquid–solid three-phase flows. Thus, this paper aims to provide a comprehensive description of the pioneering development of discrete particle models and simulations conducted by the authors.","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":"43 0","pages":"3-21"},"PeriodicalIF":0.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147886417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Formulation of Bacteriophage for Inhalation to Treat Multidrug-Resistant Pulmonary Infections. 用于吸入治疗耐多药肺部感染的噬菌体制剂。
IF 2.6 4区 材料科学
KONA Powder and Particle Journal Pub Date : 2025-01-01 Epub Date: 2024-08-14 DOI: 10.14356/kona.2025016
Vaibhav Pathak, Hak-Kim Chan, Qi Tony Zhou
{"title":"Formulation of Bacteriophage for Inhalation to Treat Multidrug-Resistant Pulmonary Infections.","authors":"Vaibhav Pathak, Hak-Kim Chan, Qi Tony Zhou","doi":"10.14356/kona.2025016","DOIUrl":"10.14356/kona.2025016","url":null,"abstract":"<p><p>Rapid development of antibiotic resistance in pathogenic bacteria and a decline in the pharmaceutical development of new antibiotics are pushing the research community to explore alternative antimicrobials that can replace or complement antibiotics. Bacteriophages (or, phages) are naturally occurring viruses that can kill bacteria with high specificity and can evolve to target resistant bacteria. Phages have been historically employed as antimicrobial agents, but they were overshadowed by the emergence of antibiotics. With a renewed focus on phages, it is important to study their clinical efficacy, safety, and formulation. Pulmonary infections have a large burden of global morbidity and frequently involve multidrug-resistant pathogens such as <i>Acinetobacter baumannii</i>, <i>Klebsiella pneumoniae</i>, <i>Mycobacterium tuberculosis</i>, and <i>Pseudomonas aeruginosa</i>. Therefore, this can be an important area of application of phages. Dry powder inhalers can be an effective strategy to deliver phages to the lungs because they are easy-to-use, portable, and capable of delivering a higher lung dose than oral or intravenous route. They also have longer shelf life and lower cold storage requirements than solutions. Therefore, the aim of the current review is to summarize recent findings on bacteriophage dry powder formulations, particularly focusing on the effect of various excipients and manufacturing factors on phage titer preservation.</p>","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":"42 ","pages":"200-212"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The 54th Symposium on Powder Technology and Special Lecture for the 30th Anniversary of the Establishment of HPTF 第54届粉末技术研讨会暨建校30周年专题讲座
IF 4.1 4区 材料科学
KONA Powder and Particle Journal Pub Date : 2023-01-10 DOI: 10.14356/kona.2023018
{"title":"The 54th Symposium on Powder Technology and Special Lecture for the 30th Anniversary of the Establishment of HPTF","authors":"","doi":"10.14356/kona.2023018","DOIUrl":"https://doi.org/10.14356/kona.2023018","url":null,"abstract":"","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":"6 1","pages":""},"PeriodicalIF":4.1,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77004184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The KONA Award 2021 2021年KONA奖
IF 4.1 4区 材料科学
KONA Powder and Particle Journal Pub Date : 2023-01-10 DOI: 10.14356/kona.2023019
{"title":"The KONA Award 2021","authors":"","doi":"10.14356/kona.2023019","DOIUrl":"https://doi.org/10.14356/kona.2023019","url":null,"abstract":"","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":"41 1","pages":""},"PeriodicalIF":4.1,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81721388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editor’s Preface 编者前言
IF 4.1 4区 材料科学
KONA Powder and Particle Journal Pub Date : 2023-01-10 DOI: 10.14356/kona.2023017
M. Naito
{"title":"Editor’s Preface","authors":"M. Naito","doi":"10.14356/kona.2023017","DOIUrl":"https://doi.org/10.14356/kona.2023017","url":null,"abstract":"","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":"184 3","pages":""},"PeriodicalIF":4.1,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72441958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
General Information 一般信息
4区 材料科学
KONA Powder and Particle Journal Pub Date : 2023-01-10 DOI: 10.14356/kona.2023020
{"title":"General Information","authors":"","doi":"10.14356/kona.2023020","DOIUrl":"https://doi.org/10.14356/kona.2023020","url":null,"abstract":"","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136326421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Intelligence and Evolutionary Approaches in Particle Technology 粒子技术中的人工智能和进化方法
IF 4.1 4区 材料科学
KONA Powder and Particle Journal Pub Date : 2023-01-01 DOI: 10.14356/kona.2024011
C. Thon, Marvin Röhl, Somayeh Hosseinhashemi, A. Kwade, C. Schilde
{"title":"Artificial Intelligence and Evolutionary Approaches in Particle Technology","authors":"C. Thon, Marvin Röhl, Somayeh Hosseinhashemi, A. Kwade, C. Schilde","doi":"10.14356/kona.2024011","DOIUrl":"https://doi.org/10.14356/kona.2024011","url":null,"abstract":"","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":"10 1","pages":""},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81774459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Applying Bubbling Fluidized-Bed Reactors for Strongly Exothermic Reactions: Focus on Methanation 鼓泡流化床反应器在强放热反应中的应用:以甲烷化为重点
IF 4.1 4区 材料科学
KONA Powder and Particle Journal Pub Date : 2023-01-01 DOI: 10.14356/kona.2024009
Philipp Riechmann, T. Schildhauer
{"title":"Applying Bubbling Fluidized-Bed Reactors for Strongly Exothermic Reactions: Focus on Methanation","authors":"Philipp Riechmann, T. Schildhauer","doi":"10.14356/kona.2024009","DOIUrl":"https://doi.org/10.14356/kona.2024009","url":null,"abstract":"","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":"11 1","pages":""},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84655784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simulation of the Classification of Manufactured Sands in the Throat Air Classifier 喉部空气分级机对砂的分级模拟
IF 4.1 4区 材料科学
KONA Powder and Particle Journal Pub Date : 2023-01-01 DOI: 10.14356/kona.2024006
H. A. Petit, E. Irassar
{"title":"Simulation of the Classification of Manufactured Sands in the Throat Air Classifier","authors":"H. A. Petit, E. Irassar","doi":"10.14356/kona.2024006","DOIUrl":"https://doi.org/10.14356/kona.2024006","url":null,"abstract":"","PeriodicalId":17828,"journal":{"name":"KONA Powder and Particle Journal","volume":"1 1","pages":""},"PeriodicalIF":4.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88430648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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