Karbala International Journal of Modern Science最新文献_第5页

Synthesizing of Alginate Coated-Silver Nanoparticles Core-Shell for Detecting of S-naproxen Enantiomer in Pharmaceutical Formulation 海藻酸盐包覆银纳米粒子核壳的合成及其对s -萘普生对映体的检测

Karbala International Journal of Modern Science Pub Date : 2023-09-21 DOI: 10.33640/2405-609x.3314

Abdolrasol Barazandeh, Ghasem Najafpour-Darz, Afshar Alihossein, Sohrab Kazemi

{"title":"Synthesizing of Alginate Coated-Silver Nanoparticles Core-Shell for Detecting of S-naproxen Enantiomer in Pharmaceutical Formulation","authors":"Abdolrasol Barazandeh, Ghasem Najafpour-Darz, Afshar Alihossein, Sohrab Kazemi","doi":"10.33640/2405-609x.3314","DOIUrl":"https://doi.org/10.33640/2405-609x.3314","url":null,"abstract":"Core-shell nanoparticles were used in a unique direct UV-Vis spectrophotometric technique to detect the S-naproxen enantiomer. Silver nanoparticles (Ag NPs) covered with sodium alginate (Alg) shell, a naturally occurring biopolymer, made the core of the nanostructure. To name a few, TEM, FESEM, UV-Visible, DLS, ZP, AFM, XRD, EDX and FT-IR are among the analytical methods used to analyze the creation of the core-shell structure. Based on obtained results, spherical Ag@ Alg NPs with an average size of 27.4 nm (DTEM), hydrolytic size of 46 nm (DDLS) and surface charge of -60.9 mV were successfully synthesized. The effect of various reaction time and pH values on determining the s-naproxen enantiomer by Ag@ Alg NPs was investigated. Determining the maximum S-naproxen enantiomer was at a reaction time of 8 min and pH 8. According to the international council for the harmonization of technical requirements for pharmaceuticals for human use (ICH) guidelines, the detection limit and quantitative limit of S-naproxen enantiomer were determined to be 1.87x10-4 mol/L and 5.64 x 10-4 mol /L. This clearly indicates that the alginate-coated silver na-noparticle","PeriodicalId":17782,"journal":{"name":"Karbala International Journal of Modern Science","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136236717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eggshell-alginate composites (EACs) as eco-friendly adsorbents for Rhodamine B uptake from aqueous solutions 蛋壳-海藻酸盐复合材料(EACs)作为生态友好型吸附剂从水溶液中吸收罗丹明B

Karbala International Journal of Modern Science Pub Date : 2023-09-21 DOI: 10.33640/2405-609x.3317

Rusna di, Mar’atus Sholihah, Nurrahmi Handayani, Muhammad Ali Zulfikar

{"title":"Eggshell-alginate composites (EACs) as eco-friendly adsorbents for Rhodamine B uptake from aqueous solutions","authors":"Rusna di, Mar’atus Sholihah, Nurrahmi Handayani, Muhammad Ali Zulfikar","doi":"10.33640/2405-609x.3317","DOIUrl":"https://doi.org/10.33640/2405-609x.3317","url":null,"abstract":"The contamination of wastewater by Rhodamine B (RhB) poses a significant environmental concern due to its negative impacts on aesthetics, ecosystems, and human well-being. This study successfully synthesized eco-friendly egg-shell-alginate composites (EACs) as adsorbents by combining alginate solution, eggshell powder, and a 2% CaCl2 solu-tion. Characterization techniques including FTIR, SEM, TGA, and SAA were employed to analyze the EACs. FTIR analysis revealed characteristic absorption peaks corresponding to -OH groups, C=O groups, C-O groups, and the pres-ence of CO32-. The structural analysis confirmed the physical mixture of functional groups from eggshells and alginate, resulting in a homogeneous EACs mixture. TGA analysis demonstrated the decomposition of eggshell calcium car-bonate (CaCO3), yielding calcium oxide (CaO) and carbon dioxide (CO2) within the 700-800°C temperature range. SAA results indicated that EACs exhibited a mesoporous structure (average pore diameter: 20-500 Å) and a higher sur-face area (6.102 m2/g) compared to eggshells. The adsorption capacity of EACs for RhB was investigated by evaluating contact time, adsorbent dosage, pH, and initial concentration. Characterization results validated the successful synthesis of EACs with enhanced thermal resistance compared to Ca-alginate. Sorption studies demonstrated the potential of EACs as effective adsorbents for RhB removal from aqueous solutions, following the Langmuir isotherm model with a maximum adsorption capacity of 151.51 mg/g. Furthermore, adsorption kinetics exhibited a pseudo-second-order mod-el. Thermodynamic analysis indicated that RhB adsorption onto EACs was exothermic (negative ΔHo) and spontaneous (negative ΔGo). The results underscore the potency of EACs as highly efficient adsorbents for the remediation of RhB-contaminated water bodies.","PeriodicalId":17782,"journal":{"name":"Karbala International Journal of Modern Science","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136237714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple structural and functional annotations based in-silico characterization of Q9BRX8 protein 基于Q9BRX8蛋白的多种结构和功能注释的硅表征

Karbala International Journal of Modern Science Pub Date : 2023-09-09 DOI: 10.33640/2405-609x.3320

Eiman Zahid, Muhammad Farhan Sarwar

{"title":"Multiple structural and functional annotations based in-silico characterization of Q9BRX8 protein","authors":"Eiman Zahid, Muhammad Farhan Sarwar","doi":"10.33640/2405-609x.3320","DOIUrl":"https://doi.org/10.33640/2405-609x.3320","url":null,"abstract":"Numerous proteins found in humans are poorly understood because there is a dearth of experimental evidence. Hypothetical proteins (HPs) or uncharacterized proteins are the terms used to describe these proteins. In this work, one of these proteins, Q9BRX8, is investigated using in-silico or bioinformatics tools to reveal its significant properties. In this regard, NCBI for the sequence retrieval, ProtParam tool for analysis of physiochemical properties, SOPMA for secondary structure prediction, SWISS-Model for homology modelling, STRING for protein-protein interaction and HDOCK for protein-protein docking analysis among other tools, were incorporated. The physiochemical characteristics indicated that Q9BRX8, which has an instability score of 32.57, is a stable protein. It was identified in other cellular compartments, such as the cytosol, mitochondria, etc., where it may be betrothed in a variety of cellular functions, according to the sub-cellular localization studies. In addition, its secondary structure consists of high percentage of alpha helices (44.10%), among other components. Additionally, it was discovered through protein-protein interactions that this protein belongs to FAM213A family suggesting that it may function as antioxidant and affect bone resorption among other crucial functions. While, molecular docking analysis indicated that Q9BRX8 had a larger degree of similarity with the HLA-G protein, scoring -332.53kcal/mol. It can be hypothesized that the functions of Q9BRX8 and the HLA-G may be associated as a result of this similarity.","PeriodicalId":17782,"journal":{"name":"Karbala International Journal of Modern Science","volume":"120 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136192446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vitro antioxidant, anti-inflammatory, and photoprotective activities of aqueous extract of the endemic plant Hammada scoparia L. from Algeria 阿尔及利亚特有植物东莨菪水提取物的体外抗氧化、抗炎和光保护活性

Karbala International Journal of Modern Science Pub Date : 2023-09-03 DOI: 10.33640/2405-609x.3310

Benine Chaima, D. A. Boutlelis, Laiche Ammar Touhami, Tlili Hajer, Tliba Ali, B. Abdelkarim, Najjaa Hanen

引用次数: 0

Biogenesis Synthesis of ZnO NPs: Its adsorption and photocatalytic activity for removal of acid black 210 dye ZnO NPs的生物合成及其对酸性黑210染料的吸附和光催化活性

Karbala International Journal of Modern Science Pub Date : 2023-08-22 DOI: 10.33640/2405-609x.3315

Zahraa A. Najm, M. Atiya, A. K. Hassan

{"title":"Biogenesis Synthesis of ZnO NPs: Its adsorption and photocatalytic activity for removal of acid black 210 dye","authors":"Zahraa A. Najm, M. Atiya, A. K. Hassan","doi":"10.33640/2405-609x.3315","DOIUrl":"https://doi.org/10.33640/2405-609x.3315","url":null,"abstract":"Abstract This study investigated the treatment of textile wastewater contaminated with Acid Black 210 dye (AB210) using zinc oxide nanoparticles (ZnO NPs) through adsorption and photocatalytic techniques. ZnO NPs were synthesized using a green synthesis process involving eucalyptus leaves as reducing and capping agents. The synthesized ZnO NPs were characterized using UV-Vis spectroscopy, SEM, EDAX, XRD, BET, Zeta potential, and FTIR techniques. The BET analysis revealed a specific surface area and total pore volume of 26.318 m 2 /g. SEM images confirmed the crystalline and spherical nature of the particles, with a particle size of 73.4 nm. A photoreactor was designed to facilitate the photo-degradation process. The study investigated the influence of key variables on the adsorption and photocatalytic break-down of AB210. The results indicated that under optimal conditions (AB210 concentration: 5 mg/L, ZnO NPs dosage: 0.75 g/L, pH: 5, and temperature: 45 °C), the removal efficiency after 180 minutes of adsorption was 62%. However, in the case of photo-degradation, complete removal of 5 mg/L AB210 was achieved within 30 minutes at a pH of 7, UV intensity of 24 W/m 2 , and temperature of 45 °C. The adsorption process exhibited the best fit with the pseudo-second-order kinetic model. Various adsorption isotherms, including Freundlich, Langmuir, Temkin, and Dubinin models, were studied, and the Langmuir isotherm provided the best fit to the experimental data (see Supplementary Materials). Fur-thermore, thermodynamic analysis indicated that the adsorption process was spontaneous, endothermic, and favorable, with Δ G°, Δ H°, and Δ S° values of -0.782 kJ/mol, 26.93 kJ/mol, and 0.086 kJ.mol/K, respectively","PeriodicalId":17782,"journal":{"name":"Karbala International Journal of Modern Science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45295667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Online Data Transmission Reduction Scheme for Energy Conservation in Wireless Video Sensor Networks 无线视频传感器网络中节能的在线数据传输缩减方案

Karbala International Journal of Modern Science Pub Date : 2023-08-22 DOI: 10.33640/2405-609x.3318

Iman K. Abbood, A. Idrees

{"title":"Online Data Transmission Reduction Scheme for Energy Conservation in Wireless Video Sensor Networks","authors":"Iman K. Abbood, A. Idrees","doi":"10.33640/2405-609x.3318","DOIUrl":"https://doi.org/10.33640/2405-609x.3318","url":null,"abstract":"Abstract Wireless Video Sensor Networks (WVSNs) are networks of low-cost, low-power camera sensor nodes. These nodes communicate locally and process information to meet an application's goal. WVSNs are extensively used in diverse monitoring applications, such as security, military, industrial, medical, and environmental monitoring. However, the transmission of large amounts of data collected by video sensor nodes in WVSNs poses challenges in terms of energy consumption, bandwidth usage, and network congestion. Reducing energy for processing and transmitting data in WVSNs is difficult due to the huge amount of sensed data in real-time. To address this issue, this paper proposes an Online Data Transmission Reduction Scheme (ODaTReS) for energy conservation in WVSNs. The data reduction by the ODaTReS is based on two phases: the sensing phase and the transmission phase. ODaTReS adapts the frame rate to limit the number of video frames captured during the sensing phase. It does this by using three efficient techniques: ORB (Oriented FAST and Rotated BRIEF), Brute-Force (BF) Matcher, and Grid-based Motion Statistics (GMS). During the transmission phase, we use an adaptive transmission threshold that is responsible for deciding whether to transmit the current captured frame or remove it. Several experiments are conducted to demonstrate the effectiveness of the ODaTReS. The proposed ODaTReS outperforms the FRABID method in terms of data reduction and energy consumption. The results reveal that ODaTReS reduced the transmitted data by 80%, compared to 43% for the FRABID method. This reduction in data transmission contributes to a decrease in the total energy consumed, which is reduced to 141.22 joules compared to the FRABID method, which consumes 173.16 joules of energy.","PeriodicalId":17782,"journal":{"name":"Karbala International Journal of Modern Science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43230458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound assisted comparative study of fucolam and so-dium alginate and impact on their physiochemical proper-ties using Box-Behnken Design 采用Box-Behnken设计对岩藻胶和海藻酸钠的超声辅助比较研究及其对其理化性质的影响

Karbala International Journal of Modern Science Pub Date : 2023-08-18 DOI: 10.33640/2405-609x.3319

U. Bagale, A. Kadi, Artem Malinin, Varisha Anjum, I. Potoroko

{"title":"Ultrasound assisted comparative study of fucolam and so-dium alginate and impact on their physiochemical proper-ties using Box-Behnken Design","authors":"U. Bagale, A. Kadi, Artem Malinin, Varisha Anjum, I. Potoroko","doi":"10.33640/2405-609x.3319","DOIUrl":"https://doi.org/10.33640/2405-609x.3319","url":null,"abstract":"Abstract The article discusses about the possibility of comparing the impact of ultrasonic treatment on fucolam and sodium algi-nate. The purpose was to study the effect of micronization on the sulfated heteropolysaccharide fucolam, analyzing its dispersed state and accessibility by reducing its molecular weight and increasing antioxidant activity. The optimization of the micronization process was carried out using the Box-Behnken Design (BBD) method, with a sonication time ranging from 15 to 45 min, power ranging from 50 to 100 W/cm2, and temperature between 30 °C and 40 °C. The fixed lower fucolam concentration was 0.1%. The results illustrated that sonochemical treatment significantly decreased the molecular weight (Mw) of fucolam compared to sodium alginate. Using BBD, the ideal treatment conditions for fu-colam were 31 °C, 62 W/cm2, and 36 min, resulting in a lower molecular weight (180 kDa), particle size (231 nm), and antioxidant activity (AOA) of 81% compared to sodium alginate, which had an Mw of 2046 kDa and an AOA of 43%. Antioxidant activity tests showed a significant increase due to the sonication treatment. The findings suggest that soni-cation treatment may be a valuable strategy to lower fucolam levels with minimal structural damage, as observed in scanning microscope images","PeriodicalId":17782,"journal":{"name":"Karbala International Journal of Modern Science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45213571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep Learning-based CAD System for Predicting the COVID-19 X-ray Images 基于深度学习的新型冠状病毒x射线图像预测CAD系统

Karbala International Journal of Modern Science Pub Date : 2023-08-18 DOI: 10.33640/2405-609x.3316

Aqeel R. Talib, H. M. Ali

引用次数: 0

Mutation-Induced Changes in the Stability, B-Cell Epitope, and Antigenicity of the Sars-Cov-2 Variant Spike Protein: A Comparative Computational Stud Sars-Cov-2变异刺突蛋白稳定性、b细胞表位和抗原性的突变诱导变化:比较计算研究

Karbala International Journal of Modern Science Pub Date : 2023-08-11 DOI: 10.33640/2405-609x.3311

N. M. Wijayanti, M. H. Widyananda, L. Muflikhah, N. Widodo

{"title":"Mutation-Induced Changes in the Stability, B-Cell Epitope, and Antigenicity of the Sars-Cov-2 Variant Spike Protein: A Comparative Computational Stud","authors":"N. M. Wijayanti, M. H. Widyananda, L. Muflikhah, N. Widodo","doi":"10.33640/2405-609x.3311","DOIUrl":"https://doi.org/10.33640/2405-609x.3311","url":null,"abstract":"Abstract The spike (S) protein is a major antigenicity site that targets neutralizing antibodies and drugs. The growing number of S protein mutations has become a severe problem for developing effective vaccines. Here, we investigated four severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants that were the most infectious and widespread during the COVID-19 pandemic to determine the trends and patterns of mutation-induced changes in the stability, B-cell epitope, and antigenicity of the SARS-CoV-2 S protein. The data showed that the Beta and Gamma variants had three mutations on the receptor-binding domain (RBD), which is the specific site on the S protein for angiotensin-converting enzyme 2 (hACE2) binding. The Delta variant had only two mutations, whereas the Omicron variant had 15 mutations on the RBD. The results showed that the stability of the S protein varied and depended on the mutation type and that Gamma and Omicron are the most stable of the four variants analyzed. The S protein–hACE2 complexes of the Beta and Gamma variants were relatively stable after 20 ns of simulation compared with those of the Delta and Omicron variants. We predicted that the B-cell epitopes of the mutant S protein would be different from those of the wildtype. Moreover, the antigenicity of Omicron changed drastically compared with that of the other variants. Bioinformatics analysis and a molecular dynamic simulation revealed that the mutations affected the stability of the S protein. A large number of mutations do not always stabilize the S protein. Mutations in Omicron significantly altered the B-cell epitope and antigenicity, which decreased vaccine effectiveness. These findings provide insights into SARS-CoV-2 evolution for vaccine development.","PeriodicalId":17782,"journal":{"name":"Karbala International Journal of Modern Science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46648356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Representing quantum spins in different coordinate systems for modelling rigid body orientation 表示不同坐标系下的量子自旋以模拟刚体方向

Karbala International Journal of Modern Science Pub Date : 2023-08-06 DOI: 10.33640/2405-609x.3313

N. Zioui, Aicha Mahmoudi, M. Tadjine

引用次数: 0