Brazilian Journal of Clinical Medicine and Review最新文献_第9页

Relationship Between Functional and Breathing Abilities in Institutionalized Elderly: A Cohort Study 机构老年人功能与呼吸能力的关系:一项队列研究

Brazilian Journal of Clinical Medicine and Review Pub Date : 2023-02-05 DOI: 10.52600/2965-0968.bjcmr.2023.1.2.3-8

Camila Raquel de Castro Silva, Carina dos Santos Cavalcante, Cláudia Stefanny de Menezes Souza, Luana Maria Farias, Amanda C. A. Almeida, José Evaldo Gonçalves Lopes Júnior, Cesário Rui Callou-Filho, Juliana Pinto Montenegro

{"title":"Relationship Between Functional and Breathing Abilities in Institutionalized Elderly: A Cohort Study","authors":"Camila Raquel de Castro Silva, Carina dos Santos Cavalcante, Cláudia Stefanny de Menezes Souza, Luana Maria Farias, Amanda C. A. Almeida, José Evaldo Gonçalves Lopes Júnior, Cesário Rui Callou-Filho, Juliana Pinto Montenegro","doi":"10.52600/2965-0968.bjcmr.2023.1.2.3-8","DOIUrl":"https://doi.org/10.52600/2965-0968.bjcmr.2023.1.2.3-8","url":null,"abstract":"Aging is a natural process with a wide range of profiles, and its changes can be physiological or pathological, even if people have the same chronological age. Here, we analyze the relationship between functional and respiratory capacities in institutionalized elderly. This research is defined as a cross-sectional, descriptive, prospective study, with a quantitative approach, carried out at the Shelter Unit for the Elderly in Fortaleza. The study consisted of 26 institutionalized elderly people able to participate in the sample. We identified that male participants predominated in this study, with an average age of 74 years with a history of smoking and alcoholism, where the majority did not undergo physical therapy. The average execution time of the Timed Up and Go Test was 18.2 seconds. When analyzing the difference in the cirtometry means, a variation was found for the axillary, xiphoid and umbilical measurements. Mean of inspiratory muscle strength of 35.2 cmH2O and expiratory 51.4 cm H2O were evaluated. When evaluating the quality of life, the physical domain was detected as the greatest value. It is concluded that the variation in functional capacity and mobility through the TUG has no correlation with the respiratory capacity assessed through cirtometry and manovacuometry.","PeriodicalId":176982,"journal":{"name":"Brazilian Journal of Clinical Medicine and Review","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125192308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From Science to Clinical 从科学到临床

Brazilian Journal of Clinical Medicine and Review Pub Date : 2023-02-05 DOI: 10.52600/2965-0968.bjcmr.2023.1.1.1-2

H. Ribeiro-Junior

引用次数: 0

HIV Vulnerability Associated with Dementia in Non-Elderly Individuals: An Integrative Review HIV易感性与非老年人痴呆相关:一项综合综述

Brazilian Journal of Clinical Medicine and Review Pub Date : 2023-02-01 DOI: 10.52600/2965-0968.bjcmr.2023.1.1.46-49

Cesário Rui Callou Filho, Rithielly Tavares dos Santos, José Evaldo Gonçalves Lopes-Júnior, Juliana Pinto Montenegro, Denise Gonçalves Moura Pinheiro, Cristiane Gomes de Sousa Campos, Helayne Martins Menezes, Edislane Silva Souza, S. S. Pinheiro

{"title":"HIV Vulnerability Associated with Dementia in Non-Elderly Individuals: An Integrative Review","authors":"Cesário Rui Callou Filho, Rithielly Tavares dos Santos, José Evaldo Gonçalves Lopes-Júnior, Juliana Pinto Montenegro, Denise Gonçalves Moura Pinheiro, Cristiane Gomes de Sousa Campos, Helayne Martins Menezes, Edislane Silva Souza, S. S. Pinheiro","doi":"10.52600/2965-0968.bjcmr.2023.1.1.46-49","DOIUrl":"https://doi.org/10.52600/2965-0968.bjcmr.2023.1.1.46-49","url":null,"abstract":"Acquired Immunodeficiency Syndrome (AIDS) was discovered in the 1980s as a sexually transmitted infectious disease and considered a major public health problem. HIV presents very accentuated neurotropism, leading to the appearance of neurological syndromes, mainly in more chronic phases of the infectious process. The most frequent alterations are vacuolar myelopathy and a picture of cerebral atrophy, progressive dementia, and peripheral neuropathies, all related to the action of HIV and the immune system itself in the central and peripheral nervous tissue. HIV-associated dementia contributes to the morbidity of the infection and is a risk factor for mortality. Prior to the use of antiretroviral therapy, over 15% of individuals with AIDS had dementia and over 15% of minor motor cognitive impairment. Advanced infection is a risk factor for the development of dementia both in the pre- and post-pharmacological treatment era. Considering the aspects, the present study aimed to carry out an integrative literature review on the pathophysiological aspects of the relationship between dementia and HIV carriers.","PeriodicalId":176982,"journal":{"name":"Brazilian Journal of Clinical Medicine and Review","volume":"39 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121230220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of Autonomic Modulation in Patients with Chronic Obstructive Pulmonary Disease 慢性阻塞性肺疾病患者自主神经调节的分析

Brazilian Journal of Clinical Medicine and Review Pub Date : 2023-01-31 DOI: 10.52600/2965-0968.bjcmr.2023.1.1.37-45

Claudia Cavalcante Campos, Dianne Dielly de Vasconcelos Ferreira, Marcilene Alves Brasil, Mayara de Sousa Carlos Aires, Guilherme Pinheiro Ferreira Silva, Amanda C. A. Almeida, José Evaldo Gonçalves Lopes-Júnior, Cesário Rui Callou-Filho, Juliana Pinto Montenegro

{"title":"Analysis of Autonomic Modulation in Patients with Chronic Obstructive Pulmonary Disease","authors":"Claudia Cavalcante Campos, Dianne Dielly de Vasconcelos Ferreira, Marcilene Alves Brasil, Mayara de Sousa Carlos Aires, Guilherme Pinheiro Ferreira Silva, Amanda C. A. Almeida, José Evaldo Gonçalves Lopes-Júnior, Cesário Rui Callou-Filho, Juliana Pinto Montenegro","doi":"10.52600/2965-0968.bjcmr.2023.1.1.37-45","DOIUrl":"https://doi.org/10.52600/2965-0968.bjcmr.2023.1.1.37-45","url":null,"abstract":"The aim of this study was to analyze autonomic modulation and factors that may be associated in patients with COPD. We carried out a cross-sectional, observational study of a quantitative nature, from the recruitment of 11 individuals with COPD, assisted by a specialized hospital in the state of Ceará. For data collection, the following were used: an evaluation form containing demographic and clinical data, prepared by the researchers; a cardiofrequency meter to measure the heart rate during and after the walk test; the Duke Activity Status Index (DASI) questionnaire to assess the capacity functional scale, the London Chest Activity of Daily Living (LCADL) scale to check the level of dyspnea and the State-Trait Anxiety Inventory (STAI) and Beck Anxiety Inventory (BAI) to analyze the level of anxiety. We identified the LCADL scale was significantly correlated with the BAI (r= 0.847; p=0.001). Also, we found that the DASI scale was negatively correlated with the BAI (r= -0.632; p=0.037), and it was verified that the lower the score, the greater the anxiety and the lower the performance in activities of daily living (ADLs). In this context, we observed that anxiety significantly impacts ADLs in the evaluated population.","PeriodicalId":176982,"journal":{"name":"Brazilian Journal of Clinical Medicine and Review","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122884168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis of Temporomandibular Disorders by Magnetic Resonance: a narrative review 磁共振诊断颞下颌疾病:叙述回顾

Brazilian Journal of Clinical Medicine and Review Pub Date : 2023-01-29 DOI: 10.52600/2965-0968.bjcmr.2023.1.1.30-36

Jaqueline Moreira Silva, Marly Barbosa Maia Souza, Regina Paula Soares Diego

{"title":"Diagnosis of Temporomandibular Disorders by Magnetic Resonance: a narrative review","authors":"Jaqueline Moreira Silva, Marly Barbosa Maia Souza, Regina Paula Soares Diego","doi":"10.52600/2965-0968.bjcmr.2023.1.1.30-36","DOIUrl":"https://doi.org/10.52600/2965-0968.bjcmr.2023.1.1.30-36","url":null,"abstract":"The temporomandibular joint (TMJ) is extremely important and complex for the organism, since it is responsible for joining the skull to the mandible. Therefore, any alteration due to injury or dysfunction can cause signs and symptoms that characterize temporomandibular joint dysfunction (TMD). Based on a narrative review, this study sought to analyze the effectiveness of the diagnosis of temporomandibular disorders by magnetic resonance imaging, through a literature review. It was evidenced that, among radiodiagnosis exams, magnetic resonance imaging (MRI) offers essential data and information regarding the mapping of the TMJ, especially in cases of dysfunction due to disk displacement. of the joint, also having the advantage of not exposing the patient to ionizing radiation, as in the case of computed tomography, for example. Thus, it is impossible not to link the benefits offered by MRI for the diagnosis of TMD. With high-resolution images, the MRI technique allows detailed and precise anatomical and functional observation, providing exclusive information on the studied segments, results that only the MRI device can achieve. Although it has limitations like any method, its incomparable advantages stand out, taking MRI to an unattainable level in relation to other techniques available for studying the TMJ.","PeriodicalId":176982,"journal":{"name":"Brazilian Journal of Clinical Medicine and Review","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115539185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is Klotho Gene a Biomarker to Pathogenesis of Myelodysplastic Syndrome in Elderly Patient? A New Hypothesis Klotho基因是老年骨髓增生异常综合征发病机制的生物标志物吗?一个新的假设

Brazilian Journal of Clinical Medicine and Review Pub Date : 2023-01-29 DOI: 10.52600/2965-0968.bjcmr.2023.1.1.3-6

H. L. Ribeiro Júnior, J. V. C. Goes

{"title":"Is Klotho Gene a Biomarker to Pathogenesis of Myelodysplastic Syndrome in Elderly Patient? A New Hypothesis","authors":"H. L. Ribeiro Júnior, J. V. C. Goes","doi":"10.52600/2965-0968.bjcmr.2023.1.1.3-6","DOIUrl":"https://doi.org/10.52600/2965-0968.bjcmr.2023.1.1.3-6","url":null,"abstract":"An important new biomarker for cancer is the Klotho, an anti-aging target, associated to proliferation and apoptosis of tumor cells. In this study, we hypothesized that the Myelodysplastic syndrome (MDS) pathogenesis, an elderly hematopoietic disease, can be affect by block of the Klotho expression, increasing ROS production in the medullary microenvironment, attenuating the DNA damage in HSCs, and leading to reduced count of blood cell precursors, characterizing the cytopenic profile of MDS patient. The absence or negative regulation of Klotho may be a poor prognostic marker of MDS, especially when patients are stratified by age. We believed that younger adult MDS patients show a higher Klotho expression while compared to old adults MDS patients, demonstrating that its expression is decreased with increasing age, representing a more aggressive disease. To confirm this hypothesis, an extensive clinical case-control study can be performed on bone marrow cell samples of MDS patients to show differential expression of Klotho gene and protein, and as this target can be modulate in this disease (based on promoter region methylation analysis). These approaches may define the Klotho as a new pathologic marker to MDS in elderly and improve future potential therapies.","PeriodicalId":176982,"journal":{"name":"Brazilian Journal of Clinical Medicine and Review","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117301748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Applicability of the Magnetic Resonance Technique during the Gestational Period: a narrative review 磁共振技术在妊娠期的适用性:叙述性回顾

Brazilian Journal of Clinical Medicine and Review Pub Date : 2023-01-29 DOI: 10.52600/2965-0968.bjcmr.2023.1.1.7-23

Guilherme Freire da Silveira Oliveira, Regina Paula Soares Diego, A. C. Oliveira

{"title":"Applicability of the Magnetic Resonance Technique during the Gestational Period: a narrative review","authors":"Guilherme Freire da Silveira Oliveira, Regina Paula Soares Diego, A. C. Oliveira","doi":"10.52600/2965-0968.bjcmr.2023.1.1.7-23","DOIUrl":"https://doi.org/10.52600/2965-0968.bjcmr.2023.1.1.7-23","url":null,"abstract":"Over the last few decades, fetal imaging has led to significant improvements in prenatal counseling and postnatal therapy options, as obstetric MRI examination mainly plays a complementary role to the morphological ultrasound study when there is any diagnostic doubt or even to confirm If there is any abnormal finding in the conventional ultrasound exam. It is worth noting that there is no evidence that MRI causes biological effects in the fetus, the exams should be reserved for patients in the second and third trimester of pregnancy. Here, we performed a literature review to point out the importance of the applicability of gestational Magnetic Resonance for the identification of changes in embryonic development, gestational pathologies, maternal diseases, sequelae of infections, fetal malformations, diagnosis of placental deficiency and creation of three-dimensional prototypes for surgical planning and fetal visualization. From this narrative review it was possible to identify that the applicability of gestational MRI is related to the identification of alterations in embryonic development, gestational pathologies in general, maternal diseases, sequelae of infections, fetal malformations, diagnosis of placental deficiency and creation of prototypes three-dimensional (3D) models for surgical planning and fetal visualization.","PeriodicalId":176982,"journal":{"name":"Brazilian Journal of Clinical Medicine and Review","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129310950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison by Gender of Muscle Power of Knee Extensors and Flexors of Athletics Athletes from the National Training and Athletics Center of the University of Fortaleza, Ceará, Brazil 巴西福塔莱萨大学国家训练与运动中心运动员膝关节伸屈肌力量的性别比较

Brazilian Journal of Clinical Medicine and Review Pub Date : 2023-01-29 DOI: 10.52600/2965-0968.bjcmr.2023.1.1.24-29

Francisco Rafael Oliveira Silva, Danilo Figueiredo Lima, M. Pinheiro

引用次数: 0