Jurnal Biodjati最新文献_第2页

Genetic Characteristics of Chloropsis cochinchinensis Gmelin, 1789 Based on The Mitochondrial DNA COI Gene 基于线粒体 DNA COI 基因的 Chloropsis cochinchinensis Gmelin, 1789 的遗传特征

Jurnal Biodjati Pub Date : 2023-05-30 DOI: 10.15575/biodjati.v8i1.20260

Jarulis Jarulis, Apin Saputra, R. H. Wibowo

{"title":"Genetic Characteristics of Chloropsis cochinchinensis Gmelin, 1789 Based on The Mitochondrial DNA COI Gene","authors":"Jarulis Jarulis, Apin Saputra, R. H. Wibowo","doi":"10.15575/biodjati.v8i1.20260","DOIUrl":"https://doi.org/10.15575/biodjati.v8i1.20260","url":null,"abstract":"The rate of illegal poaching of blue-winged leafbirds (Chloropsis cochinchinensis) throughout Indonesia, particularly Bengkulu, is quite high. However, only minimal molecular information is available for this species. We performed mtDNA COI gene sequencing to explore genetic characters (conservative site, variable site, parsimony site, and singleton site) of blue-winged leafbirds. Using Qiagen's DNeasy® Blood and Tissue Kit based on the Spin-Column Protocol, total DNA was isolated, and PCR amplification methods were performed. DNA derived from a PCR reaction was forwarded to PT. First Base Malaysia for sequencing. Using MEGA 10.0 and BIOEDIT, the COI gene nucleotide sequence data were assembled, edited, and analyzed to explore of single nucleotide polymorphism, genetic distance, and phylogeny. The 616 bp COI genes contained 566 conservative sites (C), 50 variation sites (V), 24 information parsimony sites (Pi), and 26 singleton sites (S), as indicated by the results. The greatest nucleotide base composition was cytosine (34.1–34.9%), while the lowest was guanine (15.7–16.2%). The proportion of adenine-thymine nucleotide base pairs was greater than that of guanine-cytosine (50.3%). There were 26 barcode-specific mutation sites, 17 transition substitution mutation sites, and 9 transverse substitution mutation sites. The average genetic distance between C. cochinchinensis individuals was 2.2%, but the average genetic difference between species was 9.0%. All C. cochinchinensis individuals in our sample clustered within the same clade and were distinguished from other species within the same genus. The COI gene sequences of C. cochinchinensis that we acquired are novel and can be utilized for molecular identification of the species.","PeriodicalId":17683,"journal":{"name":"Jurnal Biodjati","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139372451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic Variation of Structural and Functional Genes of SARS-CoV-2 Isolates Circulating in Banyumas (Indonesia) 印度尼西亚巴纽马地区流行的 SARS-CoV-2 分离株结构基因和功能基因的遗传变异

Jurnal Biodjati Pub Date : 2023-05-30 DOI: 10.15575/biodjati.v8i1.25132

Anwar Rovik, Clearensia Ade Bina Noviani

{"title":"Genetic Variation of Structural and Functional Genes of SARS-CoV-2 Isolates Circulating in Banyumas (Indonesia)","authors":"Anwar Rovik, Clearensia Ade Bina Noviani","doi":"10.15575/biodjati.v8i1.25132","DOIUrl":"https://doi.org/10.15575/biodjati.v8i1.25132","url":null,"abstract":"Scientists are performing various measurements to overcome the COVID-19 pandemic. The genomic mutations of SARS-CoV-2 can change their pathogenicity, infectivity, transmission, and antigenicity. This present study aimed to know a) the genetic variation of structural and functional genes of SARS-CoV-2 circulating in Banyumas and b) the potential of the Cilacap’s Harbour as a human mobility portal on the genetic variations of SARS-CoV-2 circulating in Banyumas, Central Java (Indonesia). Genomic sequence of SARS-CoV-2 isolates were taken from the Global Initiative on Sharing All Influenza Data (GISAID) and the National Center for Biotechnology Information (NCBI) online platforms. A gene cut was carried out from Wuhan reference isolate, fifteen isolates from Banyumas, and two isolates from Cilacap (Central Java) using Unipro UGENE v. 33.0 software, considering the annotation of the Wuhan-1 isolate. Genetic variations were detected among SARS-CoV-2 isolates circulating in Banyumas. The structural protein (envelope, membrane, nucleocapsid) encoding gene and the RdRp gene were highly conserved to Wuhan reference genome (Wuhan-Hu-1). Meanwhile, the ORF and the spike-encoding genes were less identical to the Wuhan reference genome. This study also proposed that human mobility from outside Central Java through Cilacap’s Harbour did not affect the genetic variation of SARS-CoV-2 isolates circulating in Banyumas (Central Java).","PeriodicalId":17683,"journal":{"name":"Jurnal Biodjati","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139372505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leaf Anatomy Profile of Begonia Section Platycentrum Sphenanthera Group From Java and Sumatera, Indonesia 印度尼西亚爪哇和苏门答腊岛海棠科 Platycentrum Sphenanthera 组的叶片解剖概况

Jurnal Biodjati Pub Date : 2023-05-30 DOI: 10.15575/biodjati.v8i1.20190

I. Q. Lailaty, Muhammad Efendi

{"title":"Leaf Anatomy Profile of Begonia Section Platycentrum Sphenanthera Group From Java and Sumatera, Indonesia","authors":"I. Q. Lailaty, Muhammad Efendi","doi":"10.15575/biodjati.v8i1.20190","DOIUrl":"https://doi.org/10.15575/biodjati.v8i1.20190","url":null,"abstract":"Anatomical studies have been used in the classification and identification of Begonia species. However, the research on Indonesian native Begonia is still limited. This study focused to evaluate the importance of leaves’ anatomy character for the identification and classification purpose of the Sphenanthera group in Java and Sumatra. A total of six individuals of four Begonia species used in this study, namely Begonia multangula, B. longifolia, B. pseudoscottii, and B. robusta. This study aimed to describe the anatomical characters of the leaves that are useful in the identification and grouping of Begonia section Platycentrum–Sphenanthera. The anatomical preparations used the paraffin method for the cross-section of leaves and the semi-permanent method for paradermal observations. In general, the epidermal cells of paradermal Begonia leaves are polygonal in shape. Consistently, Begonias have single-type stomata with an anisocytic type which are only present on the abaxial leaves. Begonia Sphenanthera group has a thin cuticle (less than 2 µm), both in the abaxial and adaxial surfaces. The lower epidermis cells are smaller than the upper epidermis cells. The mesophyll is differentiated into palisade and spongy tissue. The number and form of mesophyll tissue are varied, therefore useful for diagnosing an important character in the grouping of Begonias from this section.","PeriodicalId":17683,"journal":{"name":"Jurnal Biodjati","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139372671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Growth, Food Efficiency, and Enzyme Activities in Yellow Rasbora (Rasbora lateristriata) at Different Feeding Frequencies 不同喂食频率下黄鲈的生长、食物效率和酶活性

Jurnal Biodjati Pub Date : 2023-05-30 DOI: 10.15575/biodjati.v8i1.25029

U. Susilo, Yulia Sistina, Eko Setio Wibowo, Hanan Hassan Alsheikh Mahmoud, Hana Hana, F. Rachmawati

{"title":"Growth, Food Efficiency, and Enzyme Activities in Yellow Rasbora (Rasbora lateristriata) at Different Feeding Frequencies","authors":"U. Susilo, Yulia Sistina, Eko Setio Wibowo, Hanan Hassan Alsheikh Mahmoud, Hana Hana, F. Rachmawati","doi":"10.15575/biodjati.v8i1.25029","DOIUrl":"https://doi.org/10.15575/biodjati.v8i1.25029","url":null,"abstract":"Many studies have been conducted on the feeding frequency in fish, but there is no information on R. lateristriata. Therefore, this study aimed to determine yellow rasbora growth performance, feed efficiency, and digestive enzyme activity at different feeding frequencies. This research was conducted experimentally with four treatments and three replications. The treatments include: P1 fish were fed two times/day; P2 fish were fed three times/day; P3 fish were fed four times/day; and P4 fish were fed five times/day. In this experiment, 420 two-month-old yellow rasboras were used. The experimental results showed that body weight gain, RGR, SGR, CF, FCR, PER, body lipid & protein levels, protein and lipid retention, protease, and amylase activity were not significantly different (p>0.05) between different feeding frequencies. However, lipase and alkaline phosphatase activities differed significantly among the different feeding frequencies. Growth performance, feed efficiency, protease activity, and yellow rasbora amylase are not affected by feeding frequency between two to five times a day. Still, the highest lipase and alkaline phosphatase activity were achieved at the feeding frequency four times a day, but no effect on growth. So, feeding twice a day is considered quite efficient for the culture of yellow rasbora. The results of this study can contribute to the development of fish farming, especially the yellow rasbora, in the future.","PeriodicalId":17683,"journal":{"name":"Jurnal Biodjati","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139372683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effective Combination of Nigella sativa and Trigonella foenum-graecum Seed Extract on Wound Healing in Diabetic Mice 黑麦草和川芎籽提取物的有效复方制剂对糖尿病小鼠伤口愈合的影响

Jurnal Biodjati Pub Date : 2023-05-30 DOI: 10.15575/biodjati.v8i1.19968

Retno Susilowati, Ulfa Maynisa Rohmanningrum

{"title":"Effective Combination of Nigella sativa and Trigonella foenum-graecum Seed Extract on Wound Healing in Diabetic Mice","authors":"Retno Susilowati, Ulfa Maynisa Rohmanningrum","doi":"10.15575/biodjati.v8i1.19968","DOIUrl":"https://doi.org/10.15575/biodjati.v8i1.19968","url":null,"abstract":"High levels of free radicals in diabetic wounds often cause chronic inflammation. Nigella sativa and Trigonella foenum-graecum seed extracts are rich in antioxidants and have anti-inflammatory effects. Trigonella foenum-graecum seed extracts can also accelerate the reepithelialization process in wound healing. This study aimed to determine the combination of ethanol extract of Nigella sativa and Trigonella foenum-graecum seeds on wound length and the number of neutrophils, macrophages, fibroblasts, and collagen density in the incision wound of diabetic mice induced by streptozotocin. T. This study used three types of controls, namely Normal (Normal mice, HPMC 3%), DM (Diabetic mice, HPMC 3%), and Iodine (Diabetic mice, Povidone Iodine 10%). Topical treatment with 70% ethanol extract ointment combined with Nigella sativa and Trigonella foenum-graecum in various variations, namely N (20%:0%), T (0%:10%), NT (10%:5%), Observations of the wound healing process were carried out on 3rd, 7th and 14th day. Data were analyzed using the One Way ANOVA and Duncan Multiple Range Test. The study's results by observing the morphology of the wound length on day 7th day showed that the combination treatment of extracts of Nigella sativa and Trigonella foenum-graecum resulted in the shortest wound, which was significantly different from the wound in untreated diabetic mice. In addition, diabetic wounds without treatment showed infection, and on the contrary, the infection did not occur in wounds treated with a combination of extracts of Nigella sativa and Trigonella foenum-graecum. The results of wound histology observations showed that the combination treatment of extracts of Nigella sativa and Trigonella foenum-graecum showed a decrease in inflammation which was indicated by a significant decrease in the number of neutrophil cells, macrophages, and accelerated reepithelialization of wound healing as indicated by a significant increase in the number of fibroblasts and collagen density since the third day of treatment.","PeriodicalId":17683,"journal":{"name":"Jurnal Biodjati","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139372544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Extracellular Pectinase from ISH16 Bacteria Isolated Induced by Coffee Pulp Waste Substrate 咖啡渣底物诱导的ISH16菌胞外果胶酶

Jurnal Biodjati Pub Date : 2022-11-30 DOI: 10.15575/biodjati.v7i2.20279

Kahar Muzakhar, Farah Salma Elida, Ramdhan Putrasetya, S. Siswoyo, Rudju Winarsa, H. T. Wiyono

{"title":"An Extracellular Pectinase from ISH16 Bacteria Isolated Induced by Coffee Pulp Waste Substrate","authors":"Kahar Muzakhar, Farah Salma Elida, Ramdhan Putrasetya, S. Siswoyo, Rudju Winarsa, H. T. Wiyono","doi":"10.15575/biodjati.v7i2.20279","DOIUrl":"https://doi.org/10.15575/biodjati.v7i2.20279","url":null,"abstract":"An α-1,4-glycosidic bonds galactoses pectin, mainly composed of a D-galacturonic acid chain, are important biomaterial widely used in industries. Utilizing this material, a bioprocess, including the biocatalysis pectinase, is often needed. Pectinase production was optimized in 7 days SSF at 37°C, and the pectinase activities were daily measured by the method of Somogy-Nelson. The optimum pectinase production was 0.166 U/ml on the fourth day SSF. Purification using open column ion exchange chromatography DEAE cellulose DE-52 resulted in 1030.9 folds of pectinase purity with a yield of 25.9%. The enzyme was at optimal activity at pH six and attended stable in the pH range of 5.5-8, while optimal activity at a temperature of 50°C and was stable in the range of 30-45°C. The pectinase activity increased by 120% with the addition of 10 mM Mg2+, and 95% retained when 10 mM Ca2+ was added. The presence of 10 mM Na+, K+, and Fe2+ resulted in a slight effect of activity at 85%, 83%, and 78%. However, it was strongly inhibited by 10 mM Al3+ and retained 25%. Based on the results above, the microbial utilization of coffee pulp waste by ISH16 bacteria pectinolytic is one opportunity to produce valuable pectinase with low-cost production, so comprehensive examination in large-scale production is needed too. In this paper, all research detail steps were described.","PeriodicalId":17683,"journal":{"name":"Jurnal Biodjati","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84389389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Allopurinol Induction on Histopathological Structure of the Liver in Male Mice (Mus musculus) 别嘌呤醇对雄性小鼠肝脏组织病理结构的诱导作用

Jurnal Biodjati Pub Date : 2022-11-30 DOI: 10.15575/biodjati.v7i2.18616

D. Lestari, Fatimatuzzahra Fatimatuzzahra, Agnes Petra Sianipar, Shahnaz Shabrina Wulansari

{"title":"Allopurinol Induction on Histopathological Structure of the Liver in Male Mice (Mus musculus)","authors":"D. Lestari, Fatimatuzzahra Fatimatuzzahra, Agnes Petra Sianipar, Shahnaz Shabrina Wulansari","doi":"10.15575/biodjati.v7i2.18616","DOIUrl":"https://doi.org/10.15575/biodjati.v7i2.18616","url":null,"abstract":"Allopurinol is used to reduce total uric acid levels in the body into oxypurinol which can inhibit xanthine oxidase. Allopurinol inhibits the precursors of uric acid formation, xanthine, and hypoxanthine. However, consumption of the drugs can cause side effects on the liver. The aim of the research was to determine the effect of allopurinol induction on the liver histopathology of male mice (Mus musculus) DDY strain. The method used in this research was an experimental design used post-test only that was divided into 4 groups of 4 mice per group. The control group (P0) was given 0.5% Na-CMC, and groups I, II, and III (P1, P2, and P3) were induced by allopurinol at 10 mg/kg BW, 20 mg/kg BW, and 30 mg/kg BW for 14 days. Allopurinol induction was performed by oral gavage. The results of the research showed that treatment with allopurinol caused changes in the mice’s body weight, liver index, liver morphology, and histological structure of the liver tissue, including necrosis, steatosis, leukocyte infiltration, binuclear hepatocytes, hepatocyte swelling, congestion, sinusoid dilatation, and hemorrhage. The level of liver damage increased in line with the dose used. This research indicated that the higher the allopurinol level, the higher the level of alteration in the liver section structure. Long-term use of allopurinol can cause damage to the structure of mice liver (liver toxicity). ","PeriodicalId":17683,"journal":{"name":"Jurnal Biodjati","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82666498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Soil Contamination in Randukuning Landfill: Morphological-Physiological Responses of Celosia argentea L. and Cleome rutidosperma D.C. 兰杜库宁垃圾填埋场土壤污染的形态与生理响应

Jurnal Biodjati Pub Date : 2022-11-30 DOI: 10.15575/biodjati.v7i2.18524

A. P. Nugroho, Dwi Puji Hayati

引用次数: 0

The Epilithic Diatom Community as a Bioindicator of water quality Brangkal Subwatershed in the Mojokerto Area Mojokerto地区Brangkal小流域浅层硅藻群落作为水质生物指标的研究

Jurnal Biodjati Pub Date : 2022-11-30 DOI: 10.15575/biodjati.v7i2.20439

B. Prahardika, Widi Muhammad Lutsfi Dwi Styawan

{"title":"The Epilithic Diatom Community as a Bioindicator of water quality Brangkal Subwatershed in the Mojokerto Area","authors":"B. Prahardika, Widi Muhammad Lutsfi Dwi Styawan","doi":"10.15575/biodjati.v7i2.20439","DOIUrl":"https://doi.org/10.15575/biodjati.v7i2.20439","url":null,"abstract":"Diatoms are widely used as bioindicators of water quality because of their short life cycle and sensitivity to changes of environmental conditions in waters. One type of diatom that is used as a bioindicator is an epilithic diatom. Epilithic diatoms are one of the diatom microalgae communities attached to rock, so they are difficult to be carried away by currents. This study aimed to determine the type, composition, abundance, diversity, and dominance of epilithic diatoms found in the waters of the Brangkal subwatershed, and to determine the quality of water in the Brangkal subwatershed based on the epilithic diatom tropic index. Epilithic diatom samples were taken from 4 stations in the Brangkal subwatershed, Mojokerto Regency at the beginning of the dry season (July-August). The analysis carried out includes abundance, diversity index, dominance index, and Diatom Trophic Index (TDI). Based on the results of the study, 17 genera of epilithic diatoms were found, with the highest abundance of epilithic diatoms, including Navicula, Cocconeis, Nitszchia, and Gomphonema. The diversity index of all stations was in the medium category, with a value between 1.206 to 1.882. The lowest dominance index at station 1 was 0.167 and the highest was at station 4 with 0.373. In addition, the observed water quality is based on the Diatom Trophic Index (TDI), stations 1 to 3 are in a good category, and stations 4 are in a bad category. ","PeriodicalId":17683,"journal":{"name":"Jurnal Biodjati","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74664798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Passiflora foetida on the Number of Purkinje Cells in the Cerebellum of Albino Rats 西番莲对白化大鼠小脑浦肯野细胞数量的影响

Jurnal Biodjati Pub Date : 2022-11-30 DOI: 10.15575/biodjati.v7i2.14298

R. Susilowati, Budi Hartono

{"title":"Effects of Passiflora foetida on the Number of Purkinje Cells in the Cerebellum of Albino Rats","authors":"R. Susilowati, Budi Hartono","doi":"10.15575/biodjati.v7i2.14298","DOIUrl":"https://doi.org/10.15575/biodjati.v7i2.14298","url":null,"abstract":" Permot (Passiflora foetida) is one type of plant that has been used as a mosquito coil. Besides being effective at killing Aedes aegypti mosquitoes, mosquito coils made from permot leaf extract are also effective at killing German cockroaches and house flies. Until now there have been no reports stating the side effects of using permot leaf extract in humans. This study was designed to demonstrate the harmful side effects of inhalation of smoked mosquito coils made from permot leaf extract on the cerebellar cortex of adult male rats. Thirty-five adult male rats were used in this study. Rats were divided into 7 groups, namely group 1 as a negative control (without exposure), group 2 as a positive control (transfluthrin exposure 3000 ppm), groups 3 to 7 were treatment groups of permot leaf extract with graded doses (500 ppm, 1000 ppm, 2000 ppm, 3000 ppm, and 4000 ppm), and was treated for 12 weeks. All rats were sacrificed in a timely manner and cerebellar specimens were taken, prepared and observed using a light microscope. Previously, rats were weighed periodically to determine the effect of toxicity. The results showed that exposure to mosquito coil smoke made from 3000 ppm Transflutrin and 4000 ppm permot leaf extract caused weight loss in rats. Likewise on the weight of the rat cerebellum. The effect of decreasing the number of Purkinje cells also occurred in the group exposed to mosquito coils made from Transflutrin 3000 ppm and permot leaf extract 4000 ppm. Therefore, the safe and effective dose of mosquito coils made from permot leaves is less than 4000 ppm, because exposure to doses of more than 4000 ppm can cause degenerative changes in the cerebellar cortex.","PeriodicalId":17683,"journal":{"name":"Jurnal Biodjati","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77777577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0