Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena最新文献_第10页

Folated curcumin-gold nanoformulations: A nanotherapeutic strategy for breast cancer therapy 叶酸姜黄素金纳米制剂:乳腺癌治疗的纳米治疗策略

Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena Pub Date : 2020-09-18 DOI: 10.1116/6.0000148

Sneha Mahalunkar, G. Kundu, S. Gosavi

{"title":"Folated curcumin-gold nanoformulations: A nanotherapeutic strategy for breast cancer therapy","authors":"Sneha Mahalunkar, G. Kundu, S. Gosavi","doi":"10.1116/6.0000148","DOIUrl":"https://doi.org/10.1116/6.0000148","url":null,"abstract":"Breast cancer is considered a leading health problem, especially in women, and is a major contributor to the annual worldwide cancer mortality rate. Various drawbacks and a range of side effects are faced by cancer patients undergoing the conventional cancer therapy methods that do not always result in positive and successful outcomes. Current research introducing nanomaterials into in vivo breast cancer therapy applications has revolutionized various aspects of these therapies. These include conjugating natural compounds onto nanoparticles (NPs) such as curcumin that exhibit chemopreventive activity, and controlled drug release targeting specific organs or tumor sites, thereby reducing the side effects otherwise caused by conventional cancer therapy. Recently, folate-tagged gold nanoparticles (AuNPs) are proving to be the leading nanocarriers used in cancer treatment and detection and can also be combined with different therapies such as chemotherapy, radiotherapy, and photothermal therapy. The development of such nano-based systems possessing enzyme mimetic properties, blood compatibility, and the ability to differentiate between normal cells and cancer cell properties deems them suitable for in vivo applications and have attracted enormous attention for devising early detection and diagnosis for breast cancer. In this review, we will discuss recent progress in the use of curcumin as a chemopreventive drug in cancer therapy and review the different routes in use for the synthesis and functionalization of Au NPs. Finally, we will review the current state of research with respect to curcumin and folic acid-conjugated Au NPs and their applications in detection, diagnosis, and treatment of breast cancer.","PeriodicalId":17652,"journal":{"name":"Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78686221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Transport dynamics in a high-brightness magneto-optical-trap Li ion source 高亮度磁光阱Li离子源的输运动力学

Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena Pub Date : 2020-09-15 DOI: 10.1116/6.0000394

J. Gardner, W. McGehee, M. Stiles, J. McClelland

引用次数: 2

Electrical characterization of Si-doped conductive AlInN films grown nearly lattice-matched to c-plane GaN on sapphire by metalorganic chemical vapor deposition 金属有机化学气相沉积法在蓝宝石上生长接近晶格匹配c面GaN的掺硅导电AlInN薄膜的电学特性

Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena Pub Date : 2020-09-11 DOI: 10.1116/6.0000284

M. Miyoshi, Taiki Nakabayashi, M. Yamanaka, T. Egawa, T. Takeuchi

引用次数: 2

Simple, low degree-of-freedom load-lock and in-vacuum sample transfer 简单，低自由度负载锁定和真空样品转移

Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena Pub Date : 2020-09-11 DOI: 10.1116/6.0000495

Catlin N. Schalk, David A. Turner, Ashley R. Gans-Forrest, Matthew M. Jobbins, S. Kandel

引用次数: 1

Ga-contamination-free scanning transmission electron microscope sample preparation by rectangular-shaped oxygen-ion-beam thinning using projection ion beam optical system 用投影离子束光学系统制备矩形氧离子束减薄法制备无砷污染扫描透射电镜样品

Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena Pub Date : 2020-09-09 DOI: 10.1116/6.0000297

H. Shichi, S. Tomimatsu

引用次数: 0

Direct molecular quantification of electronic disorder in N,N′-Di-[(1-naphthyl)-N,N′-diphenyl]-1,1′-biphenyl)-4,4′-diamine on Au(111) Au(111)上N,N ' -二-[(1-萘基)-N,N ' -二苯基]-1,1 ' -联苯)-4,4 ' -二胺中电子无序的直接分子定量

Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena Pub Date : 2020-08-28 DOI: 10.1116/6.0000401

Jiuyang Wang, Jingying Wang, D. Dougherty

引用次数: 3

Dry etching strategy of spin-transfer-torque magnetic random access memory: A review 自旋-转移-转矩磁随机存储器的干刻蚀策略研究进展

Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena Pub Date : 2020-08-12 DOI: 10.1116/6.0000205

R. Islam, B. Cui, G. Miao

{"title":"Dry etching strategy of spin-transfer-torque magnetic random access memory: A review","authors":"R. Islam, B. Cui, G. Miao","doi":"10.1116/6.0000205","DOIUrl":"https://doi.org/10.1116/6.0000205","url":null,"abstract":"The spin-based memory, spin transfer torque-magnetic random access memory (STT-MRAM), has the potential to enhance the power efficiency of high density memory systems. Its desirable characteristics include nonvolatility, fast operation, and long endurance. However, dry etching of MRAM structures remains a challenge as the industry is ramping up its production. In this paper, we explore the etching strategies that have been used to etch the MRAM structures. Several etching techniques have been developed to attain optimal device performance. These are reactive ion etching, time modulated plasma etching, atomic layer etching, and ion beam etching. Sidewall profile, sidewall contamination or damage, redeposition, selectivity, and noncorrosiveness are the main factors to consider while selecting the best etching methods. This paper starts with the fundamentals of MRAM reading, writing, and storing principles and finishes with the current approaches to solve the etch challenges. For etching, the most commonly used magnetic materials such as CoFeB, CoFe, and NiFe are covered in this article.","PeriodicalId":17652,"journal":{"name":"Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89355021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Angular dependence of secondary electron yield from microporous gold surfaces 微孔金表面二次电子产率的角依赖性

Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena Pub Date : 2020-08-10 DOI: 10.1116/6.0000346

J. Ludwick, A. Iqbal, D. Gortat, J. D. Cook, M. Cahay, Peng Zhang, T. Back, S. Fairchild, M. Sparkes, W. O'Neill

引用次数: 14

Anomalous minority carrier behavior induced by chemical surface passivation solution in p-type GaSb metal–oxide–semiconductor capacitors on Si substrates 化学表面钝化溶液诱导Si衬底p型GaSb金属氧化物半导体电容器的反常少数载流子行为

Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena Pub Date : 2020-08-05 DOI: 10.1116/6.0000169

S. Sasaki, K. Dropiewski, S. Madisetti, V. Tokranov, M. Yakimov, S. Oktyabrsky

{"title":"Anomalous minority carrier behavior induced by chemical surface passivation solution in p-type GaSb metal–oxide–semiconductor capacitors on Si substrates","authors":"S. Sasaki, K. Dropiewski, S. Madisetti, V. Tokranov, M. Yakimov, S. Oktyabrsky","doi":"10.1116/6.0000169","DOIUrl":"https://doi.org/10.1116/6.0000169","url":null,"abstract":"p-type GaSb metal–oxide–semiconductor capacitors with thin InAs surface capping layers were prepared on Si(001) substrates. Epitaxial structures with superlattice metamorphic buffer layers were grown by molecular beam epitaxy. Chemical surface treatment and atomic layer deposition methods were employed for a semiconductor surface passivation and Al2O3 high-k oxide fabrication, respectively. Capacitance-voltage measurements and scanning and transmission electron microscopies were used to correlate electrical properties with the oxide-semiconductor interface structure of the capacitors. Unexpectedly, fast minority carrier response present down to liquid nitrogen temperature was observed in the capacitors passivated by an ammonium sulfide solution. This fast response was found to be related to etch pitlike surface morphology developed upon chemical passivation at the surface steps formed by microtwins and antiphase domain boundaries. Preferential InAs etching by ammonium sulfide at the surface defects was confirmed by analytical TEM studies. Very low activation energy of minority carrier response suggests the presence of electron sources under the gate; they result from growth-related surface defects that give rise to potential fluctuations of as high as half the GaSb bandgap.","PeriodicalId":17652,"journal":{"name":"Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90501782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbonization of 3D printed polymer structures for CMOS-compatible electrochemical sensors 用于cmos兼容电化学传感器的3D打印聚合物结构的碳化

Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena Pub Date : 2020-08-04 DOI: 10.1116/6.0000266

M. A. Haque, N. Lavrik, A. Hedayatipour, D. Hensley, Dayrl P. Briggs, N. Mcfarlane

{"title":"Carbonization of 3D printed polymer structures for CMOS-compatible electrochemical sensors","authors":"M. A. Haque, N. Lavrik, A. Hedayatipour, D. Hensley, Dayrl P. Briggs, N. Mcfarlane","doi":"10.1116/6.0000266","DOIUrl":"https://doi.org/10.1116/6.0000266","url":null,"abstract":"Carbon based electrodes suitable for integration with CMOS readout electronics are of great importance for a variety of emerging applications. In this study, we have looked into the prerequisites for the optimized pyrolytic conversion of 3D printed polymer microstructures and nanostructures with the goal of developing sensing electrodes for a lab-on-CMOS electrochemical system. As a result, we identified conditions for a sequence of anneals in oxidative and inert environments that yield carbonized structures on metallized substrates with improved shape retention, while also providing electrical insulation of the surrounding metal stack. We demonstrated that titanium metal layers can be conveniently used to form electrically insulating titanium oxide on the substrate outside the carbonized structures in a self-aligned fashion. However, significant shrinkage of polymer structures formed by 3D printing or stereolithography is inevitable during their pyrolysis. Furthermore, the catalytically active titanium oxide present during initial stages of carbonization leads to additional loss of carbon and significant artifacts in the resulting structures. To minimize these adverse effects of titanium oxide on the shape retention of the carbonized structures, we developed an optimized processing sequence. Various processing steps in this sequence were characterized in terms of their effects on titanium oxide growth and geometrical changes in the 3D printed structures, while impedance and Raman spectroscopy were performed to evaluate their degree of pyrolytic conversion and, therefore, potential for electrochemical sensing.","PeriodicalId":17652,"journal":{"name":"Journal of Vacuum Science & Technology. B. Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78126433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4